All Relations between cerebellum purkinje cell and cerebellum

Publication Sentence Publish Date Extraction Date Species
Joke Delbaere, Pieter Vancamp, Stijn L J Van Herck, Nele M A Bourgeois, Mary J Green, Richard J T Wingate, Veerle M Darra. MCT8 deficiency in Purkinje cells disrupts embryonic chicken cerebellar development. The Journal of endocrinology. vol 232. issue 2. 2017-06-14. PMID:27879339. electroporation of an mct8-rnai vector into the cerebellar anlage of a 3-day-old embryo allowed knockdown of mct8 in purkinje cell precursors. 2017-06-14 2023-08-13 human
Melanie D Mark, Jan Claudius Schwitalla, Michelle Groemmke, Stefan Herlitz. Keeping Our Calcium in Balance to Maintain Our Balance. Biochemical and biophysical research communications. vol 483. issue 4. 2017-06-06. PMID:27392710. the gene mutations responsible for half of the ea members and over 35 of the sca subtypes have been identified, and several have been found to be responsible for cerebellar atrophy, abnormal intracellular calcium levels, dysregulation of purkinje cell pacemaking, altered cerebellar synaptic transmission and/or ataxia in mouse models. 2017-06-06 2023-08-13 mouse
Barry E Kennedy, Amos S Hundert, Donna Goguen, Ian C G Weaver, Barbara Karte. Presymptomatic Alterations in Amino Acid Metabolism and DNA Methylation in the Cerebellum of a Murine Model of Niemann-Pick Type C Disease. The American journal of pathology. vol 186. issue 6. 2017-05-12. PMID:27083515. alterations in dna methylation were apparent in decreased expression of dna methyltransferase 3a and methyl-5'-cytosine-phosphodiester-guanine-domain binding proteins, reduced 5-methylcytosine immunoreactivity in the molecular and purkinje cell layers, demethylation of genome-wide repetitive line-1 elements, and hypermethylation in specific promoter regions of single-copy genes in npc1-deficient cerebellum at early stages of the disease. 2017-05-12 2023-08-13 mouse
Chan Chung, Matthew J Elrick, James M Dell'Orco, Zhaohui S Qin, Shanker Kalyana-Sundaram, Arul M Chinnaiyan, Vikram G Shakkottai, Andrew P Lieberma. Heat Shock Protein Beta-1 Modifies Anterior to Posterior Purkinje Cell Vulnerability in a Mouse Model of Niemann-Pick Type C Disease. PLoS genetics. vol 12. issue 5. 2017-05-12. PMID:27152617. many forms of cerebellar degeneration exhibit an anterior-to-posterior gradient of purkinje cell loss including niemann-pick type c1 (npc) disease, a lysosomal storage disorder characterized by progressive neurological deficits that often begin in childhood. 2017-05-12 2023-08-13 mouse
J W Finnie, P C Blumbergs, J Manavi. Temporal Sequence of Autolysis in the Cerebellar Cortex of the Mouse. Journal of comparative pathology. vol 154. issue 4. 2017-04-14. PMID:27156898. this study examined the temporal sequence of post-mortem changes in the cerebellar cortical granular and purkinje cell layers of mice kept at a constant ambient temperature for up to 4 weeks. 2017-04-14 2023-08-13 mouse
Elan D Loui. Linking Essential Tremor to the Cerebellum: Neuropathological Evidence. Cerebellum (London, England). vol 15. issue 3. 2017-03-06. PMID:26129713. these studies have systematically identified a broad range of structural, degenerative changes in the et cerebellum, spanning across all purkinje cell compartments. 2017-03-06 2023-08-13 Not clear
Nartnutda Morakotsriwan, Jintanaporn Wattanathorn, Woranan Kirisattayakul, Kowit Chaisiwamongko. Autistic-Like Behaviors, Oxidative Stress Status, and Histopathological Changes in Cerebellum of Valproic Acid Rat Model of Autism Are Improved by the Combined Extract of Purple Rice and Silkworm Pupae. Oxidative medicine and cellular longevity. vol 2016. 2017-03-03. PMID:27034733. the improvement of oxidative stress and purkinje cell loss was also observed in the cerebellum of vpa-treated rats. 2017-03-03 2023-08-13 rat
Chiara Di Pietro, Daniela Marazziti, Gina La Sala, Zeinab Abbaszadeh, Elisabetta Golini, Rafaele Matteoni, Glauco P Tocchini-Valentin. Primary Cilia in the Murine Cerebellum and in Mutant Models of Medulloblastoma. Cellular and molecular neurobiology. vol 37. issue 1. 2017-02-13. PMID:26935062. the mammalian g-protein-coupled receptor 37-like 1 is specifically expressed in cerebellar bergmann glia astrocytes and participates in regulating postnatal cerebellar granule neuron proliferation/differentiation and bergmann glia and purkinje neuron maturation. 2017-02-13 2023-08-13 mouse
Dario Cupolillo, Eriola Hoxha, Alessio Faralli, Annarita De Luca, Ferdinando Rossi, Filippo Tempia, Daniela Carull. Autistic-Like Traits and Cerebellar Dysfunction in Purkinje Cell PTEN Knock-Out Mice. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 41. issue 6. 2017-01-05. PMID:26538449. autistic-like traits and cerebellar dysfunction in purkinje cell pten knock-out mice. 2017-01-05 2023-08-13 mouse
Heather K Titley, Christian Hanse. Asymmetries in Cerebellar Plasticity and Motor Learning. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25578035. synaptic plasticity at the parallel fiber to purkinje cell synapse has long been considered a cellular correlate for cerebellar motor learning. 2016-12-13 2023-08-13 Not clear
G Cheron, J Márquez-Ruiz, B Da. Oscillations, Timing, Plasticity, and Learning in the Cerebellum. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25808751. according to llinás's theory, the cerebellum acts as a control machine that uses the rhythmic activity of the inferior olive to synchronize purkinje cell populations for fine-tuning of coordination. 2016-12-13 2023-08-13 Not clear
G Cheron, J Márquez-Ruiz, B Da. Oscillations, Timing, Plasticity, and Learning in the Cerebellum. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:25808751. in contrast, the ito-marr-albus theory views the cerebellum as a motor learning machine that heuristically refines synaptic weights of the purkinje cell based on error signals coming from the inferior olive. 2016-12-13 2023-08-13 Not clear
Elan D Loui. Essential Tremor: A Common Disorder of Purkinje Neurons? The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry. vol 22. issue 2. 2016-12-13. PMID:26044399. this new formulation centers on the notion that et might be a disease of the cerebellum and, more specifically, the purkinje cell (pc) population. 2016-12-13 2023-08-13 Not clear
Andrei Khilkevich, Hunter E Halverson, Jose Ernesto Canton-Josh, Michael D Mau. Links Between Single-Trial Changes and Learning Rate in Eyelid Conditioning. Cerebellum (London, England). vol 15. issue 2. 2016-12-13. PMID:26112423. the discovery of single-trial learning effects, where the presence or absence (or the number) of climbing fiber inputs produces measureable changes in purkinje cell response and in behavior, represents a major breakthrough in cerebellar learning. 2016-12-13 2023-08-13 Not clear
James S Meabon, Bertrand R Huber, Donna J Cross, Todd L Richards, Satoshi Minoshima, Kathleen F Pagulayan, Ge Li, Kole D Meeker, Brian C Kraemer, Eric C Petrie, Murray A Raskind, Elaine R Peskind, David G Coo. Repetitive blast exposure in mice and combat veterans causes persistent cerebellar dysfunction. Science translational medicine. vol 8. issue 321. 2016-12-13. PMID:26764157. purkinje cell loss was most pronounced in the ventral cerebellar lobules, suggesting that early-stage breakdown of bbb integrity may be an important factor driving long-term brain changes. 2016-12-13 2023-08-13 mouse
Giorgio Grasselli, Qionger He, Vivian Wan, John P Adelman, Gen Ohtsuki, Christian Hanse. Activity-Dependent Plasticity of Spike Pauses in Cerebellar Purkinje Cells. Cell reports. vol 14. issue 11. 2016-12-13. PMID:26972012. our findings demonstrate that spike pauses can be regulated through an activity-dependent, exclusively non-synaptic, sk2 channel-dependent mechanism and suggest that pause plasticity-by altering the purkinje cell output-may be crucial to cerebellar information storage and learning. 2016-12-13 2023-08-13 mouse
Jan Voog. Deiters' Nucleus. Its Role in Cerebellar Ideogenesis : The Ferdinando Rossi Memorial Lecture. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26054378. this nucleus, however, should be considered as a cerebellar nucleus because it receives purkinje cell axons from the vermal b zone in its dorsal portion. 2016-10-21 2023-08-13 human
Jan Cendeli. Transplantation and Stem Cell Therapy for Cerebellar Degenerations. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26155762. in purkinje cell degeneration mice, lurcher mutant mice and mouse models of spinocerebellar ataxia type 1 and type 2 and niemann-pick disease type c. despite the lack of direct comparative studies, it appears that there might be differences in graft development and functioning between various types of cerebellar degeneration. 2016-10-21 2023-08-13 mouse
Roy V Sillito. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26255945. at the center of every zone is the purkinje cell, the principal cell type of the cerebellum and sole output of the cerebellar cortex. 2016-10-21 2023-08-13 mouse
Roy V Sillito. Mossy Fibers Terminate Directly Within Purkinje Cell Zones During Mouse Development. Cerebellum (London, England). vol 15. issue 1. 2016-10-21. PMID:26255945. the traced purkinje cell zones formed a zebrin-like pattern that was defined by the expression of neurofilament heavy chain (nfh), a marker of zones in the postnatal developing cerebellum. 2016-10-21 2023-08-13 mouse