| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Lu Zhang, Yi Na Sun, Yong Mei Li, Lai Xiang Lin, Yan Ye, Yu Qin Yan, Zu Pei Che. Effect of different iodine nutrition on cerebellum Pcp-2 in rat offspring during lactation. Biological trace element research. vol 143. issue 3. 2012-03-16. PMID:21344292. |
purkinje cell protein-2 is a cell-specific marker of the cerebellum purkinje cell and is a suitable indicator for observing the postnatal development of the cerebellum after birth. |
2012-03-16 |
2023-08-12 |
rat |
| Lu Zhang, Yi Na Sun, Yong Mei Li, Lai Xiang Lin, Yan Ye, Yu Qin Yan, Zu Pei Che. Effect of different iodine nutrition on cerebellum Pcp-2 in rat offspring during lactation. Biological trace element research. vol 143. issue 3. 2012-03-16. PMID:21344292. |
we measured the purkinje cell protein-2 mrna and protein levels in the rat cerebellum in the critical postnatal (14 days after birth) and maturation periods (28 days after birth) to determine the effect of different nutritional iodine levels on cerebellum growth in the offspring during lactation. |
2012-03-16 |
2023-08-12 |
rat |
| Lu Zhang, Yi Na Sun, Yong Mei Li, Lai Xiang Lin, Yan Ye, Yu Qin Yan, Zu Pei Che. Effect of different iodine nutrition on cerebellum Pcp-2 in rat offspring during lactation. Biological trace element research. vol 143. issue 3. 2012-03-16. PMID:21344292. |
however, mild iodine deficiency and excessive iodine maintained almost normal thyroid function in maternal and neonatal rats and normal purkinje cell protein-2 mrna and protein levels in offspring's cerebellum. |
2012-03-16 |
2023-08-12 |
rat |
| Lu Zhang, Yi Na Sun, Yong Mei Li, Lai Xiang Lin, Yan Ye, Yu Qin Yan, Zu Pei Che. Effect of different iodine nutrition on cerebellum Pcp-2 in rat offspring during lactation. Biological trace element research. vol 143. issue 3. 2012-03-16. PMID:21344292. |
we conclude that severe iodine deficiency could significantly reduce purkinje cell protein-2 mrna and its protein levels, indicating that the cerebellum development was retarded, but mild iodine deficiency and excessive iodine could maintain them at an approximately normal level by the mother's and offspring's compensations, especially by the mother's mammary glands. |
2012-03-16 |
2023-08-12 |
rat |
| Kjeld Andersen, Birgitte Bo Andersen, Bente Pakkenber. Stereological quantification of the cerebellum in patients with Alzheimer's disease. Neurobiology of aging. vol 33. issue 1. 2012-03-13. PMID:20728248. |
the cerebellum was divided into 5 regions and the purkinje and granule cell number and density, cortical volume, molecular and granular layer volume and thickness, white matter volume, surface area, and the purkinje cell gradient were stereologically estimated. |
2012-03-13 |
2023-08-12 |
human |
| Taisuke Miyazaki, Miwako Yamasaki, Kouichi Hashimoto, Maya Yamazaki, Manabu Abe, Hiroshi Usui, Masanobu Kano, Kenji Sakimura, Masahiko Watanab. Cav2.1 in cerebellar Purkinje cells regulates competitive excitatory synaptic wiring, cell survival, and cerebellar biochemical compartmentalization. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 32. issue 4. 2012-03-12. PMID:22279216. |
in the adult cerebellum, each purkinje cell (pc) is innervated by a single climbing fiber (cf) in proximal dendrites and 10(5)-10(6) parallel fibers (pfs) in distal dendrites. |
2012-03-12 |
2023-08-12 |
mouse |
| Javier S Recio, Manuel Álvarez-Dolado, David Díaz, Fernando C Baltanás, Marina Piquer-Gil, José R Alonso, Eduardo Weruag. Bone marrow contributes simultaneously to different neural types in the central nervous system through different mechanisms of plasticity. Cell transplantation. vol 20. issue 8. 2012-03-08. PMID:21294954. |
in contrast, this difference was not observed in the cerebellum, where purkinje cell degeneration had been completed. |
2012-03-08 |
2023-08-12 |
mouse |
| Sonja Janmaat, Yvette Akwa, Mohamed Doulazmi, Joëlle Bakouche, Vanessa Gautheron, Philippe Liere, Bernard Eychenne, Antoine Pianos, Paul Luiten, Ton Groothuis, Etienne-Emile Baulieu, Jean Mariani, Rachel M Sherrard, Florence Frédéri. Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival. Age (Dordrecht, Netherlands). vol 33. issue 4. 2012-02-21. PMID:21222044. |
age-related purkinje cell death is steroid dependent: rorα haplo-insufficiency impairs plasma and cerebellar steroids and purkinje cell survival. |
2012-02-21 |
2023-08-12 |
mouse |
| Sonja Janmaat, Yvette Akwa, Mohamed Doulazmi, Joëlle Bakouche, Vanessa Gautheron, Philippe Liere, Bernard Eychenne, Antoine Pianos, Paul Luiten, Ton Groothuis, Etienne-Emile Baulieu, Jean Mariani, Rachel M Sherrard, Florence Frédéri. Age-related Purkinje cell death is steroid dependent: RORα haplo-insufficiency impairs plasma and cerebellar steroids and Purkinje cell survival. Age (Dordrecht, Netherlands). vol 33. issue 4. 2012-02-21. PMID:21222044. |
to test this, we examined purkinje cell numbers, plasma sex steroids and cerebellar neurosteroid concentrations during normal ageing (wild-type mice, wt), in our model of precocious ageing (rora(+/sg), heterozygous staggerer mice in which expression of the neuroprotective factor rorα is disrupted) and after long-term hormone insufficiency (wt post-gonadectomy). |
2012-02-21 |
2023-08-12 |
mouse |
| Parthiv Haldipur, Upasna Bharti, Corinne Alberti, Chitra Sarkar, Geetika Gulati, Soumya Iyengar, Pierre Gressens, Shyamala Man. Preterm delivery disrupts the developmental program of the cerebellum. PloS one. vol 6. issue 8. 2012-02-15. PMID:21858122. |
the two groups were assessed on quantitative measures that included molecular markers of granule neuron, purkinje neuron and bergmann glia differentiation, as well as the expression of the sonic hedgehog signaling pathway, that is important for cerebellar growth. |
2012-02-15 |
2023-08-12 |
human |
| Dan-Anders Jirenhed, Germund Hesslo. Learning stimulus intervals--adaptive timing of conditioned purkinje cell responses. Cerebellum (London, England). vol 10. issue 3. 2012-01-13. PMID:21416378. |
according to the cerebellar cortical conditioning model, this conditioned purkinje cell response drives the overt blink. |
2012-01-13 |
2023-08-12 |
Not clear |
| Dan-Anders Jirenhed, Germund Hesslo. Learning stimulus intervals--adaptive timing of conditioned purkinje cell responses. Cerebellum (London, England). vol 10. issue 3. 2012-01-13. PMID:21416378. |
to test this prediction, in vivo recordings of purkinje cell activity were performed in decerebrate ferrets during conditioning, using direct stimulation of cerebellar mossy and climbing fibre afferents as conditioned and unconditioned stimuli. |
2012-01-13 |
2023-08-12 |
Not clear |
| Adrien Demilly, Stacey L Reeber, Samrawit A Gebre, Roy V Sillito. Neurofilament heavy chain expression reveals a unique parasagittal stripe topography in the mouse cerebellum. Cerebellum (London, England). vol 10. issue 3. 2012-01-13. PMID:20127431. |
despite the general uniformity in cellular composition of the adult cerebellum (cb), the expression of proteins such as zebrinii/aldolasec and the small heat shock protein hsp25 reveal striking patterns of parasagittal purkinje cell (pc) stripes. |
2012-01-13 |
2023-08-12 |
mouse |
| Daniela Necchi, Selene Lomoio, Elda Scherin. Dysfunction of the ubiquitin-proteasome system in the cerebellum of aging Ts65Dn mice. Experimental neurology. vol 232. issue 2. 2011-12-20. PMID:21867700. |
searching for the cause of purkinje cell degeneration, we have studied the ubiquitin-proteasome system (ups) in the cerebellum of aging ts65dn mice. |
2011-12-20 |
2023-08-12 |
mouse |
| Yasushi Iwasaki, Keiko Mori, Masumi Ito, Maya Mimuro, Mari Yoshid. [An autopsied case of progressive supranuclear palsy, initially diagnosed as spinocerebellar degeneration with severe olivopontocerebellar involvement]. Rinsho shinkeigaku = Clinical neurology. vol 51. issue 10. 2011-12-20. PMID:22019867. |
the cerebellar dentate nucleus showed neuron loss with grumose degeneration and the purkinje neuron layer showed neuron loss and bergmann's gliosis with torpedoes. |
2011-12-20 |
2023-08-12 |
Not clear |
| Tatiana Hurtado de Mendoza, Carlos G Perez-Garcia, Todd T Kroll, Nien H Hoong, Dennis D M O'Leary, Inder M Verm. Antiapoptotic protein Lifeguard is required for survival and maintenance of Purkinje and granular cells. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 41. 2011-12-13. PMID:21957071. |
we found that lfg plays a role in cerebellar development by affecting cerebellar size, internal granular layer (igl) thickness, and purkinje cell (pc) development. |
2011-12-13 |
2023-08-12 |
mouse |
| Gauthami S Kondagari, Jessica Yang, Rosanne M Taylo. Investigation of cerebrocortical and cerebellar pathology in canine fucosidosis and comparison to aged brain. Neurobiology of disease. vol 41. issue 3. 2011-12-12. PMID:21056668. |
preclinical fucosidosis cerebral cortex and cerebellum revealed early increases in all neurodegenerative markers studied including apoptosis (2.1 fold), pyramidal neuronal loss (0.9 fold decrease) and purkinje cell loss (1.2 fold decrease) compared to age matched controls. |
2011-12-12 |
2023-08-12 |
Not clear |
| W Y Tam, C K Y Leung, K K Tong, K M Kwa. Foxp4 is essential in maintenance of Purkinje cell dendritic arborization in the mouse cerebellum. Neuroscience. vol 172. 2011-12-05. PMID:20951773. |
foxp4 is essential in maintenance of purkinje cell dendritic arborization in the mouse cerebellum. |
2011-12-05 |
2023-08-12 |
mouse |
| Baiping Wang, Wilbur Harrison, Paul A Overbeek, Hui Zhen. Transposon mutagenesis with coat color genotyping identifies an essential role for Skor2 in sonic hedgehog signaling and cerebellum development. Development (Cambridge, England). vol 138. issue 20. 2011-11-28. PMID:21937600. |
loss of skor2 leads to defective purkinje cell development, a severe reduction of granule cell proliferation and a malformed cerebellum. |
2011-11-28 |
2023-08-12 |
mouse |
| Andrew McKeon, Jennifer A Tracy, Sean J Pittock, Joseph E Parisi, Christopher J Klein, Vanda A Lenno. Purkinje cell cytoplasmic autoantibody type 1 accompaniments: the cerebellum and beyond. Archives of neurology. vol 68. issue 10. 2011-11-23. PMID:21670387. |
purkinje cell cytoplasmic autoantibody type 1 accompaniments: the cerebellum and beyond. |
2011-11-23 |
2023-08-12 |
Not clear |