| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andrew McKeon, Jennifer A Tracy, Sean J Pittock, Joseph E Parisi, Christopher J Klein, Vanda A Lenno. Purkinje cell cytoplasmic autoantibody type 1 accompaniments: the cerebellum and beyond. Archives of neurology. vol 68. issue 10. 2011-11-23. PMID:21670387. |
to investigate the full extent of purkinje cell cytoplasmic autoantibody type 1 autoimmunity (classically associated with paraneoplastic cerebellar degeneration) from clinical, immunohistochemical, and neuropathological perspectives. |
2011-11-23 |
2023-08-12 |
Not clear |
| Seung-Hyuk Chung, Marco Calafiore, Jennifer M Plane, David E Pleasure, Wenbin Den. Apoptosis inducing factor deficiency causes reduced mitofusion 1 expression and patterned Purkinje cell degeneration. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:20974255. |
next, we investigated the cerebellar pathology of harlequin mice in an age-dependent fashion, and identified a striking process of progressive and patterned purkinje cell degeneration. |
2011-11-22 |
2023-08-12 |
mouse |
| Seung-Hyuk Chung, Marco Calafiore, Jennifer M Plane, David E Pleasure, Wenbin Den. Apoptosis inducing factor deficiency causes reduced mitofusion 1 expression and patterned Purkinje cell degeneration. Neurobiology of disease. vol 41. issue 2. 2011-11-22. PMID:20974255. |
we further showed that the patterned purkinje cell degeneration was dependent on caspase but not poly(adp-ribose) polymerase-1 (parp-1) activation, and confirmed the marked decrease of mfn1 in the harlequin cerebellum. |
2011-11-22 |
2023-08-12 |
mouse |
| Anett Jandke, Clive Da Costa, Rocio Sancho, Emma Nye, Bradley Spencer-Dene, Axel Behren. The F-box protein Fbw7 is required for cerebellar development. Developmental biology. vol 358. issue 1. 2011-11-22. PMID:21827743. |
this resulted in decreased cerebellar size, reduced purkinje cell number and defects in axonal arborisation. |
2011-11-22 |
2023-08-12 |
mouse |
| Ulf Edener, Veronica Bernard, Yorck Hellenbroich, Gabriele Gillessen-Kaesbach, Christine Zühlk. Two dominantly inherited ataxias linked to chromosome 16q22.1: SCA4 and SCA31 are not allelic. Journal of neurology. vol 258. issue 7. 2011-11-15. PMID:21267591. |
autosomal dominant spinocerebellar ataxias (scas) are heterogeneous neurological disorders characterised by cerebellar dysfunction mostly due to purkinje cell degeneration. |
2011-11-15 |
2023-08-12 |
Not clear |
| Rodrigo Alvarez-Icaza, Kwabena Boahe. Deep cerebellar neurons mirror the spinal cord's gain to implement an inverse controller. Biological cybernetics. vol 105. issue 1. 2011-11-14. PMID:21789607. |
here, to continue to validate our mapping, we propose that climbing fiber input into the deep cerebellar nucleus (dcn) triggers rebounds, primed by purkinje cell inhibition, implementing gain on io's signal to mirror the spinal cord reflex's gain thereby achieving inverse control. |
2011-11-14 |
2023-08-12 |
Not clear |
| Mariaelena Repici, Rosine Wehrlé, Xanthi Antoniou, Tiziana Borsello, Isabelle Dusar. c-Jun N-terminal kinase (JNK) and p38 play different roles in age-related Purkinje cell death in murine organotypic culture. Cerebellum (London, England). vol 10. issue 2. 2011-11-10. PMID:21191679. |
this cell death is age-dependent and has been proposed as indirect evidence for the programmed purkinje cell death occurring in in vivo cerebellum. |
2011-11-10 |
2023-08-12 |
mouse |
| Mariaelena Repici, Rosine Wehrlé, Xanthi Antoniou, Tiziana Borsello, Isabelle Dusar. c-Jun N-terminal kinase (JNK) and p38 play different roles in age-related Purkinje cell death in murine organotypic culture. Cerebellum (London, England). vol 10. issue 2. 2011-11-10. PMID:21191679. |
here, we studied whether c-jun n-terminal kinase (jnk) and p38 kinase pathways contribute to the purkinje cell death observed in cerebellar slice cultures obtained from p3 mice. |
2011-11-10 |
2023-08-12 |
mouse |
| A H Rajput, A Rajpu. Significance of cerebellar Purkinje cell loss to pathogenesis of essential tremor. Parkinsonism & related disorders. vol 17. issue 6. 2011-10-24. PMID:21636310. |
some recent studies indicate that most essential tremor (et) cases have cerebellar pathology characterized by purkinje cell (pc) loss and its sequelae. |
2011-10-24 |
2023-08-12 |
Not clear |
| Minyoung Shin, Setareh H Moghadam, Chris Sekirnjak, Martha W Bagnall, Kristine E Kolkman, Richard Jacobs, Michael Faulstich, Sascha du La. Multiple types of cerebellar target neurons and their circuitry in the vestibulo-ocular reflex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 30. 2011-10-07. PMID:21795530. |
the cerebellum influences behavior and cognition exclusively via purkinje cell synapses onto neurons in the deep cerebellar and vestibular nuclei. |
2011-10-07 |
2023-08-12 |
mouse |
| Minyoung Shin, Setareh H Moghadam, Chris Sekirnjak, Martha W Bagnall, Kristine E Kolkman, Richard Jacobs, Michael Faulstich, Sascha du La. Multiple types of cerebellar target neurons and their circuitry in the vestibulo-ocular reflex. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 30. 2011-10-07. PMID:21795530. |
using a combination of anatomical tracing and electrophysiological recordings in transgenic mouse lines, we identified several classes of neurons in the medial vestibular nucleus that receive purkinje cell synapses from the cerebellar flocculus. |
2011-10-07 |
2023-08-12 |
mouse |
| Megumi Kaneko, Kazuhiko Yamaguchi, Mototsugu Eiraku, Motohiko Sato, Norio Takata, Yoshimoto Kiyohara, Masayoshi Mishina, Hajime Hirase, Tsutomu Hashikawa, Mineko Kengak. Remodeling of monoplanar Purkinje cell dendrites during cerebellar circuit formation. PloS one. vol 6. issue 5. 2011-10-05. PMID:21655286. |
remodeling of monoplanar purkinje cell dendrites during cerebellar circuit formation. |
2011-10-05 |
2023-08-12 |
mouse |
| Kouichi Hashimoto, Mika Tsujita, Taisuke Miyazaki, Kazuo Kitamura, Maya Yamazaki, Hee-Sup Shin, Masahiko Watanabe, Kenji Sakimura, Masanobu Kan. Postsynaptic P/Q-type Ca2+ channel in Purkinje cell mediates synaptic competition and elimination in developing cerebellum. Proceedings of the National Academy of Sciences of the United States of America. vol 108. issue 24. 2011-09-29. PMID:21628556. |
postsynaptic p/q-type ca2+ channel in purkinje cell mediates synaptic competition and elimination in developing cerebellum. |
2011-09-29 |
2023-08-12 |
mouse |
| Andrew King, Satomi Maekawa, Istvan Bodi, Claire Troakes, Safa Al-Sarra. Ubiquitinated, p62 immunopositive cerebellar cortical neuronal inclusions are evident across the spectrum of TDP-43 proteinopathies but are only rarely additionally immunopositive for phosphorylation-dependent TDP-43. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 31. issue 3. 2011-09-22. PMID:21118398. |
in 11 of the tdp-43 proteinopathies (26%) there were numerous p62-positive cerebellar inclusions, predominantly within the granular layer, but also the molecular and purkinje cell layer. |
2011-09-22 |
2023-08-12 |
Not clear |
| Michelle Y Owens, Kedra L Wallace, Naila Mamoon, Josephine Wyatt-Ashmead, William A Bennet. Absence of neurotoxicity with medicinal grade terbutaline in the rat model. Reproductive toxicology (Elmsford, N.Y.). vol 31. issue 4. 2011-09-20. PMID:21262341. |
brains collected 24 h after last injection were used to determine corpus-callosum thickness, purkinje cell and neuronal number in the cerebellum. |
2011-09-20 |
2023-08-12 |
rat |
| Neal H Barmack, Vadim Yakhnits. Microlesions of the inferior olive reduce vestibular modulation of Purkinje cell complex and simple spikes in mouse cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 27. 2011-09-09. PMID:21734274. |
microlesions of the inferior olive reduce vestibular modulation of purkinje cell complex and simple spikes in mouse cerebellum. |
2011-09-09 |
2023-08-12 |
mouse |
| Cynthia J M Kane, Kevin D Phelan, Lihong Han, Renea R Smith, Jin Xie, James C Douglas, Paul D Dre. Protection of neurons and microglia against ethanol in a mouse model of fetal alcohol spectrum disorders by peroxisome proliferator-activated receptor-γ agonists. Brain, behavior, and immunity. vol 25 Suppl 1. 2011-08-08. PMID:21376806. |
furthermore, investigations using a newly developed mouse model of fasd and stereological cell counting methods in the cerebellum elucidate that ethanol administration to neonates is toxic to both purkinje cell neurons as well as microglia, and that in vivo administration of ppar-γ agonists protects these cells. |
2011-08-08 |
2023-08-12 |
mouse |
| Takashi Matsuwaki, Rei Asakura, Masatoshi Suzuki, Keitaro Yamanouchi, Masugi Nishihar. Age-dependent changes in progranulin expression in the mouse brain. The Journal of reproduction and development. vol 57. issue 1. 2011-08-04. PMID:20962456. |
in the wild-type mice, intense immunoreactivity was observed in several brain regions including the cingulate and piriform cortices, the pyramidal cell layer and dentate gyrus of the hippocampus, the amygdala, the ventromedial and arcuate nuclei of the hypothalamus and the purkinje cell layer in the cerebellum. |
2011-08-04 |
2023-08-12 |
mouse |
| Simona Foscarin, Danilo Ponchione, Ermira Pajaj, Ketty Leto, Maciej Gawlak, Grzegorz M Wilczynski, Ferdinando Rossi, Daniela Carull. Experience-dependent plasticity and modulation of growth regulatory molecules at central synapses. PloS one. vol 6. issue 1. 2011-08-02. PMID:21304956. |
accordingly, we found that in mutant mice lacking a crucial perineuronal net component, cartilage link protein 1, perineuronal nets around cerebellar neurons are disrupted and plasticity of purkinje cell terminal is enhanced. |
2011-08-02 |
2023-08-12 |
mouse |
| Lan Zhu, Tiziana Sacco, Piergiorgio Strata, Benedetto Sacchett. Basolateral amygdala inactivation impairs learning-induced long-term potentiation in the cerebellar cortex. PloS one. vol 6. issue 1. 2011-08-02. PMID:21304962. |
in the cerebellar vermis the parallel fibers (pf) to purkinje cell (pc) synapse is potentiated one day following fear learning. |
2011-08-02 |
2023-08-12 |
rat |