| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| James M Bowe. Model-founded explorations of the roles of molecular layer inhibition in regulating purkinje cell responses in cerebellar cortex: more trouble for the beam hypothesis. Frontiers in cellular neuroscience. vol 4. 2011-07-14. PMID:20877427. |
for most of the last 50 years, the functional interpretation for inhibition in cerebellar cortical circuitry has been dominated by the relatively simple notion that excitatory and inhibitory dendritic inputs sum, and if that sum crosses threshold at the soma the purkinje cell generates an action potential. |
2011-07-14 |
2023-08-12 |
Not clear |
| A M Kammon, R S Brar, S Sodhi, H S Banga, H S Sandh. Neuropathological studies of chickens following exposure to chlorpyrifos. Toxicology international. vol 17. issue 2. 2011-07-14. PMID:21170250. |
cerebellum showed congestion and hemorrhages in the granular layer and necrosis of purkinje cell. |
2011-07-14 |
2023-08-12 |
Not clear |
| Seung-Hyuk Chung, Chul-Tae Kim, Young-Gil Jeong, Nam-Seob Le. TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice. Anatomy & cell biology. vol 43. issue 1. 2011-07-14. PMID:21190007. |
tbr2-immunopsitive unipolar brush cells are associated with ectopic zebrin ii-immunoreactive purkinje cell clusters in the cerebellum of scrambler mice. |
2011-07-14 |
2023-08-12 |
mouse |
| Seung-Hyuk Chung, Chul-Tae Kim, Young-Gil Jeong, Nam-Seob Le. TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice. Anatomy & cell biology. vol 43. issue 1. 2011-07-14. PMID:21190007. |
scrambler mice exhibit severe cerebellum abnormalities, including the failure of embryonic purkinje cell dispersal and a complete absence of foliation due to a mutation in the disabled-1 adaptor protein. |
2011-07-14 |
2023-08-12 |
mouse |
| Seung-Hyuk Chung, Chul-Tae Kim, Young-Gil Jeong, Nam-Seob Le. TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice. Anatomy & cell biology. vol 43. issue 1. 2011-07-14. PMID:21190007. |
because scrambler mice closely mimic normal embryonic day 18 cerebellum, we examined whether tbr2-positive ubcs are associated with purkinje cell cluster markers such as zebrin ii, which is the most studied compartmentation marker in the cerebellum. |
2011-07-14 |
2023-08-12 |
mouse |
| Seung-Hyuk Chung, Chul-Tae Kim, Young-Gil Jeong, Nam-Seob Le. TBR2-immunopsitive unipolar brush cells are associated with ectopic zebrin II-immunoreactive Purkinje cell clusters in the cerebellum of scrambler mice. Anatomy & cell biology. vol 43. issue 1. 2011-07-14. PMID:21190007. |
in addition, tbr2-positive ubcs are found associated with ectopic zebrin ii-immunoreactive purkinje cell clusters in scrambler cerebellum. |
2011-07-14 |
2023-08-12 |
mouse |
| William Wisden, Andrew J Murray, Christina McClure, Peer Wulf. Studying Cerebellar Circuits by Remote Control of Selected Neuronal Types with GABA(A) Receptors. Frontiers in molecular neuroscience. vol 2. 2011-07-14. PMID:20076763. |
we found that chronic disruption of the mli-purkinje cell synapse strongly impaired cerebellar learning of the vestibular occular reflex (vor), presumably by disrupting the temporal patterns of purkinje cell activity. |
2011-07-14 |
2023-08-12 |
mouse |
| Osman Fikret Sonmez, Ersan Odaci, Orhan Bas, Süleyman Kapla. Purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 MHz electromagnetic field. Brain research. vol 1356. 2011-06-17. PMID:20691167. |
purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 mhz electromagnetic field. |
2011-06-17 |
2023-08-12 |
human |
| Osman Fikret Sonmez, Ersan Odaci, Orhan Bas, Süleyman Kapla. Purkinje cell number decreases in the adult female rat cerebellum following exposure to 900 MHz electromagnetic field. Brain research. vol 1356. 2011-06-17. PMID:20691167. |
therefore, it is suggested that long duration exposure to 900 mhz emf leads to decreases of purkinje cell numbers in the female rat cerebellum. |
2011-06-17 |
2023-08-12 |
human |
| Melanie D Mark, Takashi Maejima, Denise Kuckelsberg, Jong W Yoo, Robert A Hyde, Viral Shah, Davina Gutierrez, Rosa L Moreno, Wolfgang Kruse, Jeffrey L Noebels, Stefan Herlitz. Delayed postnatal loss of P/Q-type calcium channels recapitulates the absence epilepsy, dyskinesia, and ataxia phenotypes of genomic Cacna1a mutations. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 11. 2011-06-15. PMID:21411672. |
to visualize p/q-type ca(2+) channels and dissect their role in neuronal networks at distinct developmental stages, we created a novel conditional cacna1a knock-in mouse by inserting the floxed green fluorescent protein derivative citrine into the first exon of cacna1a and then crossed it with a postnatally expressing pcp2-cre line for delayed purkinje cell (pc) gene deletion within the cerebellum and sparsely in forebrain (purky). |
2011-06-15 |
2023-08-12 |
mouse |
| Tomoyuki Honda, Kan Fujino, Daisuke Okuzaki, Naohiro Ohtaki, Yusuke Matsumoto, Masayuki Horie, Takuji Daito, Masayuki Itoh, Keizo Tomonag. Upregulation of insulin-like growth factor binding protein 3 in astrocytes of transgenic mice that express Borna disease virus phosphoprotein. Journal of virology. vol 85. issue 9. 2011-06-14. PMID:21325425. |
furthermore, we demonstrated that insulin-like growth factor signaling is disturbed in the p-tg cerebellum, a factor that might be involved in the increased vulnerability of purkinje cell neurons in the brain. |
2011-06-14 |
2023-08-12 |
mouse |
| Michael H Myoga, Wade G Regeh. Calcium microdomains near R-type calcium channels control the induction of presynaptic long-term potentiation at parallel fiber to purkinje cell synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 31. issue 14. 2011-06-09. PMID:21471358. |
we focus on presynaptic ltp at parallel fiber to purkinje cell synapses in the cerebellum (pf-ltp), which is mediated by calcium/calmodulin-stimulated adenylyl cyclases. |
2011-06-09 |
2023-08-12 |
Not clear |
| C E Andreescu, F Prestori, F Brandalise, A D'Errico, M T G De Jeu, P Rossi, L Botta, G Kohr, P Perin, E D'Angelo, C I De Zeeu. NR2A subunit of the N-methyl D-aspartate receptors are required for potentiation at the mossy fiber to granule cell synapse and vestibulo-cerebellar motor learning. Neuroscience. vol 176. 2011-06-01. PMID:21185357. |
traditionally studies aimed at elucidating the molecular mechanisms underlying cerebellar motor learning have been focused on plasticity at the parallel fiber to purkinje cell synapse. |
2011-06-01 |
2023-08-12 |
mouse |
| Tobias Huth, Andrea Rittger, Paul Saftig, Christian Alzheime. β-Site APP-cleaving enzyme 1 (BACE1) cleaves cerebellar Na+ channel β4-subunit and promotes Purkinje cell firing by slowing the decay of resurgent Na+ current. Pflugers Archiv : European journal of physiology. vol 461. issue 3. 2011-05-20. PMID:21246381. |
β-site app-cleaving enzyme 1 (bace1) cleaves cerebellar na+ channel β4-subunit and promotes purkinje cell firing by slowing the decay of resurgent na+ current. |
2011-05-20 |
2023-08-12 |
mouse |
| Marissa C Blank, Inessa Grinberg, Emmanuel Aryee, Christine Laliberte, Victor V Chizhikov, R Mark Henkelman, Kathleen J Mille. Multiple developmental programs are altered by loss of Zic1 and Zic4 to cause Dandy-Walker malformation cerebellar pathogenesis. Development (Cambridge, England). vol 138. issue 6. 2011-05-02. PMID:21307096. |
zic mutant folial patterning abnormalities correlated with disrupted cerebellar anlage gene expression and purkinje cell topography during late embryonic stages; however, this phenotype was shh independent. |
2011-05-02 |
2023-08-12 |
mouse |
| Lisa Chakrabarti, Jeremiah Eng, Nishi Ivanov, Gwenn A Garden, Albert R La Spad. Autophagy activation and enhanced mitophagy characterize the Purkinje cells of pcd mice prior to neuronal death. Molecular brain. vol 2. 2011-05-02. PMID:19640278. |
as p62 levels were decreased in pcd cerebellum, our findings suggest that pcd purkinje cell neurons can execute effective autophagy. |
2011-05-02 |
2023-08-12 |
mouse |
| Toni L Uhlendorf, Brooke H Van Kummer, Ben B Yaspelkis, Randy W Cohe. Neuroprotective effects of moderate aerobic exercise on the spastic Han-Wistar rat, a model of ataxia. Brain research. vol 1369. 2011-04-21. PMID:21062622. |
histological examination of the cerebellum revealed a 62% increase in purkinje cell survival of the runners. |
2011-04-21 |
2023-08-12 |
rat |
| C Catharina Müller, Tam H Nguyen, Barbara Ahlemeyer, Mallika Meshram, Nishreen Santrampurwala, Siyu Cao, Peter Sharp, Pamela B Fietz, Eveline Baumgart-Vogt, Denis I Cran. PEX13 deficiency in mouse brain as a model of Zellweger syndrome: abnormal cerebellum formation, reactive gliosis and oxidative stress. Disease models & mechanisms. vol 4. issue 1. 2011-04-06. PMID:20959636. |
pex13 brain mutants exhibit defects in reflex and motor development that correlate with impaired cerebellar fissure and cortical layer formation, granule cell migration and purkinje cell layer development. |
2011-04-06 |
2023-08-12 |
mouse |
| M-C Le Guen, Chris I De Zeeu. Presynaptic plasticity at cerebellar parallel fiber terminals. Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232210. |
over recent decades, substantial research has been done to explore the mechanisms of postsynaptic changes that may sustain learning processes in the cerebellum, especially bidirectional plasticity at the parallel fiber to purkinje cell synapse. |
2011-04-05 |
2023-08-12 |
Not clear |
| M-C Le Guen, Chris I De Zeeu. Presynaptic plasticity at cerebellar parallel fiber terminals. Functional neurology. vol 25. issue 3. 2011-04-05. PMID:21232210. |
here we review the current models of granular layer processing in the framework of cerebellar functioning with special emphasis on the presynaptic modulations of operations at the parallel fiber to purkinje cell synapse. |
2011-04-05 |
2023-08-12 |
Not clear |