| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Steven U Walkley, Jakub Sikora, Matthew Micsenyi, Cristin Davidson, Kostantin Dobreni. Lysosomal compromise and brain dysfunction: examining the role of neuroaxonal dystrophy. Biochemical Society transactions. vol 38. issue 6. 2011-03-14. PMID:21118103. |
as nad is found early in disease and thus may be a contributor to purkinje cell dysfunction and death, understanding its link to lysosomal compromise could lead to therapies designed to prevent its occurrence and thereby ameliorate cerebellar dysfunction. |
2011-03-14 |
2023-08-12 |
Not clear |
| M A Haque, M Khalil, M Khalil, S Z Sultana, S Mannan, M Rahman, A Ara, T Begum, S Choudhury, N Haqu. Morphometry of purkinje cell body of cerebellum in bangladeshi cadaver. Mymensingh medical journal : MMJ. vol 19. issue 4. 2011-03-10. PMID:20956889. |
morphometry of purkinje cell body of cerebellum in bangladeshi cadaver. |
2011-03-10 |
2023-08-12 |
human |
| Thomas Sangrey, Dieter Jaege. Analysis of distinct short and prolonged components in rebound spiking of deep cerebellar nucleus neurons. The European journal of neuroscience. vol 32. issue 10. 2011-02-28. PMID:21039958. |
overall, our results demonstrate that multiphasic dcn rebound properties could be elicited differentially by different levels of purkinje cell activation, and thus create a rich repertoire of potential rebound dynamics in the cerebellar control of motor timing. |
2011-02-28 |
2023-08-12 |
Not clear |
| Wolfgang Wagner, Stephan D Brenowitz, John A Hamme. Myosin-Va transports the endoplasmic reticulum into the dendritic spines of Purkinje neurons. Nature cell biology. vol 13. issue 1. 2011-02-28. PMID:21151132. |
extension of the endoplasmic reticulum (er) into dendritic spines of purkinje neurons is required for cerebellar synaptic plasticity and is disrupted in animals with null mutations in myo5a, the gene encoding myosin-va. we show here that myosin-va acts as a point-to-point organelle transporter to pull er as cargo into purkinje neuron spines. |
2011-02-28 |
2023-08-12 |
Not clear |
| Kwok-Keung Tai, Daniel D Truon. Memantine exacerbates myoclonic jerks in a rat model of posthypoxic myoclonus. Brain research. vol 1343. 2011-02-15. PMID:20434435. |
in contrast, the number of fluoro-jade b positive degenerating neurons in the purkinje cell layer of the cerebellum did not differ significantly between the memantine-treated and the saline-treated posthypoxic rats. |
2011-02-15 |
2023-08-12 |
rat |
| Kazuhiko Sawada, Hiromi Sakata-Haga, Yoshihiro Fuku. Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya. Brain research. vol 1343. 2011-02-15. PMID:20462503. |
alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive purkinje cell stripes in zebrin ii-defined transverse zone of the cerebellum of rolling mouse nagoya. |
2011-02-15 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Hiromi Sakata-Haga, Yoshihiro Fuku. Alternating array of tyrosine hydroxylase and heat shock protein 25 immunopositive Purkinje cell stripes in zebrin II-defined transverse zone of the cerebellum of rolling mouse Nagoya. Brain research. vol 1343. 2011-02-15. PMID:20462503. |
these results revealed an alternating array of th immunopositive purkinje cell subsets with hsp25 immunopositive purkinje cells in the zebrin ii-defined transverse zone of the rolling mouse cerebellum. |
2011-02-15 |
2023-08-12 |
mouse |
| Tatsuya Ohyama, Horatiu Voicu, Brian Kalmbach, Michael D Mau. A decrementing form of plasticity apparent in cerebellar learning. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 50. 2011-02-09. PMID:21159969. |
together, these observations suggest a plasticity mechanism in the cerebellum that is induced during training sessions and fades within 23 h. to formalize this hypothesis more specifically, we show that incorporating a short-lasting potentiation at the granule cell to purkinje cell synapses in a computer simulation of the cerebellum reproduces these behavioral effects. |
2011-02-09 |
2023-08-12 |
rabbit |
| Olga Gómez, Begoña Ballester-Lurbe, Enric Poch, José E Mesonero, José Terrad. Developmental regulation of glucose transporters GLUT3, GLUT4 and GLUT8 in the mouse cerebellar cortex. Journal of anatomy. vol 217. issue 5. 2011-02-03. PMID:20819112. |
however, the external granule cell layer, purkinje cell cytoplasm and cytoplasm of the other cerebellar cells lack glut3 expression. |
2011-02-03 |
2023-08-12 |
mouse |
| Yong-Sik Kim, G Jean Harry, Hong Soon Kang, David Goulding, Rob N Wine, Grace E Kissling, Grace Liao, Anton M Jette. Altered cerebellar development in nuclear receptor TAK1/ TR4 null mice is associated with deficits in GLAST(+) glia, alterations in social behavior, motor learning, startle reactivity, and microglia. Cerebellum (London, England). vol 9. issue 3. 2011-01-25. PMID:20393820. |
previously, deficiency in the expression of the nuclear orphan receptor tak1 was found to be associated with delayed cerebellar granule cell migration and purkinje cell maturation with a permanent deficit in foliation of lobules vi–vii, suggesting a role for tak1 in cerebellum development. |
2011-01-25 |
2023-08-12 |
mouse |
| Reza Tadayonnejad, Dustin Anderson, Michael L Molineux, W Hamish Mehaffey, Kusala Jayasuriya, Ray W Turne. Rebound discharge in deep cerebellar nuclear neurons in vitro. Cerebellum (London, England). vol 9. issue 3. 2011-01-25. PMID:20396983. |
neurons of the deep cerebellar nuclei (dcn) play a critical role in defining the output of cerebellum in the course of encoding purkinje cell inhibitory inputs. |
2011-01-25 |
2023-08-12 |
rat |
| Michael Ariel, Michael E Brow. Origin and timing of voltage-sensitive dye signals within layers of the turtle cerebellar cortex. Brain research. vol 1357. 2011-01-14. PMID:20707989. |
white matter microstimulation in sagittal slices (near the ventricular surface of the turtle cerebellum) activated the granule cell and purkinje cell layers, but not the molecular layer. |
2011-01-14 |
2023-08-12 |
Not clear |
| Jerí L Bryant, John D Boughter, Suzhen Gong, Mark S LeDoux, Detlef H Hec. Cerebellar cortical output encodes temporal aspects of rhythmic licking movements and is necessary for normal licking frequency. The European journal of neuroscience. vol 32. issue 1. 2011-01-13. PMID:20597972. |
we recorded purkinje cell simple and complex spike activity in awake mice during licking, and determined the behavioral consequences of loss of cerebellar function. |
2011-01-13 |
2023-08-12 |
mouse |
| Hugo Merchan. "Apneas" in Purkinje cell activity: evidence for the bistability of membrane potential in the awake cat cerebellum. Frontiers in neuroscience. vol 4. 2011-01-04. PMID:20582258. |
"apneas" in purkinje cell activity: evidence for the bistability of membrane potential in the awake cat cerebellum. |
2011-01-04 |
2023-08-12 |
cat |
| Price E Dickson, Tiffany D Rogers, Nobel Del Mar, Loren A Martin, Detlef Heck, Charles D Blaha, Daniel Goldowitz, Guy Mittlema. Behavioral flexibility in a mouse model of developmental cerebellar Purkinje cell loss. Neurobiology of learning and memory. vol 94. issue 2. 2010-12-13. PMID:20566377. |
using a mouse model, we tested the hypothesis that developmental abnormalities of the cerebellum, including purkinje cell loss, result in behavioral inflexibility. |
2010-12-13 |
2023-08-12 |
mouse |
| Claire Piochon, Carole Levenes, Gen Ohtsuki, Christian Hanse. Purkinje cell NMDA receptors assume a key role in synaptic gain control in the mature cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068337. |
purkinje cell nmda receptors assume a key role in synaptic gain control in the mature cerebellum. |
2010-12-13 |
2023-08-12 |
mouse |
| Claire Piochon, Carole Levenes, Gen Ohtsuki, Christian Hanse. Purkinje cell NMDA receptors assume a key role in synaptic gain control in the mature cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068337. |
a classic view in cerebellar physiology holds that purkinje cells do not express functional nmda receptors and that, therefore, postsynaptic nmda receptors are not involved in the induction of long-term depression (ltd) at parallel fiber (pf) to purkinje cell synapses. |
2010-12-13 |
2023-08-12 |
mouse |
| Claire Piochon, Carole Levenes, Gen Ohtsuki, Christian Hanse. Purkinje cell NMDA receptors assume a key role in synaptic gain control in the mature cerebellum. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 45. 2010-12-13. PMID:21068337. |
here, we show that in the mature mouse cerebellum ltd (induced by paired pf and cf activation), but not long-term potentiation (ltp; pf stimulation alone) at pf to purkinje cell synapses is blocked by bath application of the nmda receptor antagonist d-2-amino-5-phosphonovaleric acid (d-apv). |
2010-12-13 |
2023-08-12 |
mouse |
| Joanna Giza, Michael J Urbanski, Francesca Prestori, Bhaswati Bandyopadhyay, Annie Yam, Victor Friedrich, Kevin Kelley, Egidio D'Angelo, Mitchell Goldfar. Behavioral and cerebellar transmission deficits in mice lacking the autism-linked gene islet brain-2. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 44. 2010-12-08. PMID:21048139. |
experimental disruption of the ib2 gene in mice reduces ampa and enhances nmda receptor-mediated glutamatergic transmission in cerebellum, changes the morphology of purkinje cell dendritic arbors, and induces motor and cognitive deficits suggesting an autism phenotype. |
2010-12-08 |
2023-08-12 |
mouse |
| Céline Auger, David Ogde. AMPA receptor activation controls type I metabotropic glutamate receptor signalling via a tyrosine kinase at parallel fibre-Purkinje cell synapses. The Journal of physiology. vol 588. issue Pt 16. 2010-12-07. PMID:20603338. |
metabotropic glutamate receptors type 1 (mglur1s) and ionotropic ampa receptors (ampars) are colocalized at parallel fibre (pf) to purkinje cell synapses of the cerebellum. |
2010-12-07 |
2023-08-12 |
rat |