| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Daisuke Furutama, Noriyuki Morita, Riya Takano, Yukiko Sekine, Tetsushi Sadakata, Yo Shinoda, Kanehiro Hayashi, Yuriko Mishima, Katsuhiko Mikoshiba, Richard Hawkes, Teiichi Furuich. Expression of the IP3R1 promoter-driven nls-lacZ transgene in Purkinje cell parasagittal arrays of developing mouse cerebellum. Journal of neuroscience research. vol 88. issue 13. 2010-12-06. PMID:20632399. |
expression of the ip3r1 promoter-driven nls-lacz transgene in purkinje cell parasagittal arrays of developing mouse cerebellum. |
2010-12-06 |
2023-08-12 |
mouse |
| Daisuke Furutama, Noriyuki Morita, Riya Takano, Yukiko Sekine, Tetsushi Sadakata, Yo Shinoda, Kanehiro Hayashi, Yuriko Mishima, Katsuhiko Mikoshiba, Richard Hawkes, Teiichi Furuich. Expression of the IP3R1 promoter-driven nls-lacZ transgene in Purkinje cell parasagittal arrays of developing mouse cerebellum. Journal of neuroscience research. vol 88. issue 13. 2010-12-06. PMID:20632399. |
ip(3)r1-nls-lacz transgene expression was detected at a single purkinje cell level over the surface of a whole-mount x-gal-stained cerebellum because of nuclear accumulation of the nls-lacz activity. |
2010-12-06 |
2023-08-12 |
mouse |
| Tae-Beom Seo, Bo-Kyun Kim, Il-Gyu Ko, Dong-Hyun Kim, Mal-Soon Shin, Chang-Ju Kim, Jin-Hwan Yoon, Hong Ki. Effect of treadmill exercise on Purkinje cell loss and astrocytic reaction in the cerebellum after traumatic brain injury. Neuroscience letters. vol 481. issue 3. 2010-11-16. PMID:20603186. |
effect of treadmill exercise on purkinje cell loss and astrocytic reaction in the cerebellum after traumatic brain injury. |
2010-11-16 |
2023-08-12 |
rat |
| Kazuhiko Sawada, Yoshihiro Fuku. Zebrin II expressing Purkinje cell phenotype-related and -unrelated cerebellar abnormalities in Cav2.1 mutant, rolling mouse Nagoya. TheScientificWorldJournal. vol 10. 2010-11-16. PMID:20953553. |
zebrin ii expressing purkinje cell phenotype-related and -unrelated cerebellar abnormalities in cav2.1 mutant, rolling mouse nagoya. |
2010-11-16 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Yoshihiro Fuku. Zebrin II expressing Purkinje cell phenotype-related and -unrelated cerebellar abnormalities in Cav2.1 mutant, rolling mouse Nagoya. TheScientificWorldJournal. vol 10. 2010-11-16. PMID:20953553. |
while there are no obvious cerebellar deformations in this mutant mouse, the altered functions of purkinje cells can be revealed as a reduced expression of type 1 ryanodine receptor (ryr1) in all purkinje cells uniformly throughout the cerebellum, and as an ectopic expression of tyrosine hydroxylase (th) in the purkinje cell subsets with the zebrin ii-immunopositive phenotype. |
2010-11-16 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Yoshihiro Fuku. Zebrin II expressing Purkinje cell phenotype-related and -unrelated cerebellar abnormalities in Cav2.1 mutant, rolling mouse Nagoya. TheScientificWorldJournal. vol 10. 2010-11-16. PMID:20953553. |
thus, to determine whether or not cerebellar abnormalities are related to purkinje cell populations revealed by zebrin ii expression is essential for enhancing our understanding of the pathogenesis of hereditary cerebellar ataxic mutants such as rolling mice. |
2010-11-16 |
2023-08-12 |
mouse |
| Kevin Kemp, Kelly Hares, Elizabeth Mallam, Kate J Heesom, Neil Scolding, Alastair Wilkin. Mesenchymal stem cell-secreted superoxide dismutase promotes cerebellar neuronal survival. Journal of neurochemistry. vol 114. issue 6. 2010-10-19. PMID:20028455. |
here we have performed a series of experiments showing that human bone marrow-derived mscs are able to protect cultured rodent cerebellar neurons, and specifically cells expressing purkinje cell markers, against either nitric oxide exposure or withdrawal of trophic support via cell-cell contact and/or secretion of soluble factors, or through secretion of soluble factors alone. |
2010-10-19 |
2023-08-12 |
human |
| John E Greenlee, Susan A Clawson, Kenneth E Hill, Blair L Wood, Ikuo Tsunoda, Noel G Carlso. Purkinje cell death after uptake of anti-Yo antibodies in cerebellar slice cultures. Journal of neuropathology and experimental neurology. vol 69. issue 10. 2010-10-15. PMID:20838245. |
purkinje cell death after uptake of anti-yo antibodies in cerebellar slice cultures. |
2010-10-15 |
2023-08-12 |
rat |
| John E Greenlee, Susan A Clawson, Kenneth E Hill, Blair L Wood, Ikuo Tsunoda, Noel G Carlso. Purkinje cell death after uptake of anti-Yo antibodies in cerebellar slice cultures. Journal of neuropathology and experimental neurology. vol 69. issue 10. 2010-10-15. PMID:20838245. |
these findings indicate that autoantibodies directed against intracellular purkinje cell proteins can be taken up to cause cell death and suggest that anti-yo antibody may be directly involved in the pathogenesis of paraneoplastic cerebellar degeneration. |
2010-10-15 |
2023-08-12 |
rat |
| M Schonewille, A Belmeguenai, S K Koekkoek, S H Houtman, H J Boele, B J van Beugen, Z Gao, A Badura, G Ohtsuki, W E Amerika, E Hosy, F E Hoebeek, Y Elgersma, C Hansel, C I De Zeeu. Purkinje cell-specific knockout of the protein phosphatase PP2B impairs potentiation and cerebellar motor learning. Neuron. vol 67. issue 4. 2010-09-27. PMID:20797538. |
studies have provided supportive evidence for a potential role of kinase-mediated long-term depression (ltd) at the parallel fiber to purkinje cell synapse in cerebellar learning. |
2010-09-27 |
2023-08-12 |
Not clear |
| Xinjie Xu, Rajendra Kedlaya, Hitoshi Higuchi, Sakae Ikeda, Monica J Justice, Vijayasaradhi Setaluri, Akihiro Iked. Mutation in archain 1, a subunit of COPI coatomer complex, causes diluted coat color and Purkinje cell degeneration. PLoS genetics. vol 6. issue 5. 2010-09-13. PMID:20502676. |
nur17 mutant mice exhibit both coat-color dilution and ataxia due to purkinje cell degeneration in the cerebellum. |
2010-09-13 |
2023-08-12 |
mouse |
| Celia Quevedo, Vincent Sauzeau, Mauricio Menacho-Márquez, Antonio Castro-Castro, Xosé R Bustel. Vav3-deficient mice exhibit a transient delay in cerebellar development. Molecular biology of the cell. vol 21. issue 6. 2010-09-08. PMID:20089829. |
consistent with this hypothesis, we demonstrate using vav3-deficient mice that this protein contributes to purkinje cell dendritogenesis, the survival of granule cells of the internal granular layer, the timely migration of granule cells of the external granular layer, and to the formation of the cerebellar intercrural fissure. |
2010-09-08 |
2023-08-12 |
mouse |
| Claire S Oldfield, Alain Marty, Brandon M Stel. Interneurons of the cerebellar cortex toggle Purkinje cells between up and down states. Proceedings of the National Academy of Sciences of the United States of America. vol 107. issue 29. 2010-09-01. PMID:20615960. |
the mode switch demonstrated here indicates that a single presynaptic interneuron can have opposite effects on the output of a given purkinje cell, which introduces a unique type of synaptic interaction that may play an important role in cerebellar signaling. |
2010-09-01 |
2023-08-12 |
Not clear |
| Roy V Sillitoe, Michael W Vogel, Alexandra L Joyne. Engrailed homeobox genes regulate establishment of the cerebellar afferent circuit map. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 30. issue 30. 2010-08-20. PMID:20668186. |
the spatial organization of the cerebellar afferent map has remarkable correspondence to two aspects of intrinsic patterning within the cerebellum embodied by a series of lobules and purkinje cell (pc)-striped gene expression. |
2010-08-20 |
2023-08-12 |
mouse |
| J D Brady, C Mohr, D J Ross. Vesicular GABA release delays the onset of the Purkinje cell terminal depolarization without affecting tissue swelling in cerebellar slices during simulated ischemia. Neuroscience. vol 168. issue 1. 2010-08-20. PMID:20226232. |
vesicular gaba release delays the onset of the purkinje cell terminal depolarization without affecting tissue swelling in cerebellar slices during simulated ischemia. |
2010-08-20 |
2023-08-12 |
rat |
| Lisa Chakrabarti, Rabaab Zahra, Stephen M Jackson, Parsa Kazemi-Esfarjani, Bryce L Sopher, Amanda G Mason, Thomas Toneff, Soyoung Ryu, Scott Shaffer, Janice W Kansy, Jeremiah Eng, Gennifer Merrihew, Michael J MacCoss, Anne Murphy, David R Goodlett, Vivian Hook, Craig L Bennett, Leo J Pallanck, Albert R La Spad. Mitochondrial dysfunction in NnaD mutant flies and Purkinje cell degeneration mice reveals a role for Nna proteins in neuronal bioenergetics. Neuron. vol 66. issue 6. 2010-08-06. PMID:20620870. |
the purkinje cell degeneration (pcd) mouse is a recessive model of neurodegeneration, involving cerebellum and retina. |
2010-08-06 |
2023-08-12 |
mouse |
| Christine M Pedroaren. Mechanisms supporting transfer of inhibitory signals into the spike output of spontaneously firing cerebellar nuclear neurons in vitro. Cerebellum (London, England). vol 9. issue 1. 2010-07-02. PMID:20148319. |
cerebellar cortical signals are carried to their principal target, the deep cerebellar nuclear neurons (dcns), via the inhibitory pathway formed by purkinje cell (pc) axons. |
2010-07-02 |
2023-08-12 |
Not clear |
| C A Duffin, R McFarland, J R Sarna, M W Vogel, C L Armstron. Heat shock protein 25 expression and preferential Purkinje cell survival in the lurcher mutant mouse cerebellum. The Journal of comparative neurology. vol 518. issue 11. 2010-06-28. PMID:20394049. |
heat shock protein 25 expression and preferential purkinje cell survival in the lurcher mutant mouse cerebellum. |
2010-06-28 |
2023-08-12 |
mouse |
| C A Duffin, R McFarland, J R Sarna, M W Vogel, C L Armstron. Heat shock protein 25 expression and preferential Purkinje cell survival in the lurcher mutant mouse cerebellum. The Journal of comparative neurology. vol 518. issue 11. 2010-06-28. PMID:20394049. |
the spatial organization of the mouse cerebellum into transverse zones and parasagittal stripes is reflected during the temporal progression of purkinje cell death in the lurcher mutant mouse (+/lc). |
2010-06-28 |
2023-08-12 |
mouse |
| L S Kin. ENCEPHALOPATHY FOLLOWING INJECTIONS OF BONE MARROW EXTRACT. The Journal of experimental medicine. vol 70. issue 3. 2010-06-23. PMID:19870911. |
small areas of softening may appear in the cerebellum as a result, but this is considered a secondary process, independent of the purkinje cell loss. |
2010-06-23 |
2023-08-12 |
human |