| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S-H Chung, H Marzban, L Croci, G G Consalez, R Hawke. Purkinje cell subtype specification in the cerebellar cortex: early B-cell factor 2 acts to repress the zebrin II-positive Purkinje cell phenotype. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18403128. |
in the murine cerebellum, ebf2 expression is restricted to the zebrin ii-immunonegative (zebrin ii-) purkinje cell population. |
2009-06-08 |
2023-08-12 |
mouse |
| S-H Chung, H Marzban, L Croci, G G Consalez, R Hawke. Purkinje cell subtype specification in the cerebellar cortex: early B-cell factor 2 acts to repress the zebrin II-positive Purkinje cell phenotype. Neuroscience. vol 153. issue 3. 2009-06-08. PMID:18403128. |
we have identified multiple cerebellar defects in the ebf2 null mouse involving a combination of selective purkinje cell death and ectopic expression of multiple genes normally restricted to the zebrin ii- subset. |
2009-06-08 |
2023-08-12 |
mouse |
| Hirotaka Sakamoto, Kazuyoshi Ukena, Mitsuhiro Kawata, Kazuyoshi Tsutsu. Expression, localization and possible actions of 25-Dx, a membraneassociated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: a new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid. Cerebellum (London, England). vol 7. issue 1. 2009-06-08. PMID:18418663. |
expression, localization and possible actions of 25-dx, a membraneassociated putative progesterone-binding protein, in the developing purkinje cell of the cerebellum: a new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid. |
2009-06-08 |
2023-08-12 |
rat |
| Hirotaka Sakamoto, Kazuyoshi Ukena, Mitsuhiro Kawata, Kazuyoshi Tsutsu. Expression, localization and possible actions of 25-Dx, a membraneassociated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: a new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid. Cerebellum (London, England). vol 7. issue 1. 2009-06-08. PMID:18418663. |
a series of our studies have demonstrated that the rat purkinje cell, a cerebellar neuron, actively produces progesterone de novo from cholesterol only during neonatal life and progesterone promotes dendritic growth, spinogenesis and synaptogenesis via its nuclear receptor in this neuron. |
2009-06-08 |
2023-08-12 |
rat |
| Hirotaka Sakamoto, Kazuyoshi Ukena, Mitsuhiro Kawata, Kazuyoshi Tsutsu. Expression, localization and possible actions of 25-Dx, a membraneassociated putative progesterone-binding protein, in the developing Purkinje cell of the cerebellum: a new insight into the biosynthesis, metabolism and multiple actions of progesterone as a neurosteroid. Cerebellum (London, England). vol 7. issue 1. 2009-06-08. PMID:18418663. |
thus the purkinje cell serves as an excellent cellular model for understanding the formation of cerebellar neuronal circuit in relation to genomic neurosteroid actions. |
2009-06-08 |
2023-08-12 |
rat |
| Yei-Tsung Chen, Loretta L Collins, Shu-Shi Chang, Chawnshang Chan. The roles of testicular orphan nuclear receptor 4 (TR4) in cerebellar development. Cerebellum (London, England). vol 7. issue 1. 2009-06-08. PMID:18418664. |
in postnatal, neuronal-specific tr4 knockout mice, architectural changes in the cerebellum were similar to those seen in tr4(-/-) animals, suggesting that tr4 function in neuronal lineages might be important for cerebellar morphogenesis, and that the effect on purkinje cell development is likely mediated by changes elsewhere, such as in granule cells, or is highly dependent on developmental stage. |
2009-06-08 |
2023-08-12 |
mouse |
| Siqiong June Liu, Philippe Lachamp, Yu Liu, Iaroslav Savtchouk, Lu Su. Long-term synaptic plasticity in cerebellar stellate cells. Cerebellum (London, England). vol 7. issue 4. 2009-05-18. PMID:18855095. |
inhibitory transmission controls the action potential firing rate and pattern of purkinje cell activity in the cerebellum. |
2009-05-18 |
2023-08-12 |
Not clear |
| Anders Rasmussen, Dan-Anders Jirenhed, Germund Hesslo. Simple and complex spike firing patterns in Purkinje cells during classical conditioning. Cerebellum (London, England). vol 7. issue 4. 2009-05-18. PMID:18931885. |
paired peripheral forelimb and periocular stimulation, as well as paired direct stimulation of cerebellar afferent pathways (mossy and climbing fibers) causes acquisition of a pause response in purkinje cell simple spike firing. |
2009-05-18 |
2023-08-12 |
human |
| Kazuhiko Sawada, Abul Kalam Azad, Hiromi Sakata-Haga, Nam-Seob Lee, Young-Gil Jeong, Yoshihiro Fuku. Striking pattern of Purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. Acta neurobiologiae experimentalis. vol 69. issue 1. 2009-05-18. PMID:19325647. |
striking pattern of purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. |
2009-05-18 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Abul Kalam Azad, Hiromi Sakata-Haga, Nam-Seob Lee, Young-Gil Jeong, Yoshihiro Fuku. Striking pattern of Purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. Acta neurobiologiae experimentalis. vol 69. issue 1. 2009-05-18. PMID:19325647. |
this study revisited to examine whether a purkinje cell loss occurred in the cerebellum of tottering mice. |
2009-05-18 |
2023-08-12 |
mouse |
| Kazuhiko Sawada, Abul Kalam Azad, Hiromi Sakata-Haga, Nam-Seob Lee, Young-Gil Jeong, Yoshihiro Fuku. Striking pattern of Purkinje cell loss in cerebellum of an ataxic mutant mouse, tottering. Acta neurobiologiae experimentalis. vol 69. issue 1. 2009-05-18. PMID:19325647. |
those results predict that the susceptibility to the cav2.1 gene defect is different among purkinje cell phenotypes of the tottering cerebellum rather than the expression pattern of mutated cav2.1 channels. |
2009-05-18 |
2023-08-12 |
mouse |
| E D Louis, J Benito-León, F Bermejo-Parej. Population-based study of baseline ethanol consumption and risk of incident essential tremor. Journal of neurology, neurosurgery, and psychiatry. vol 80. issue 5. 2009-05-08. PMID:19359288. |
recent postmortem studies have demonstrated pathological changes, including purkinje cell loss, in the cerebellum in essential tremor (et). |
2009-05-08 |
2023-08-12 |
Not clear |
| E D Louis, J Benito-León, F Bermejo-Parej. Population-based study of baseline ethanol consumption and risk of incident essential tremor. Journal of neurology, neurosurgery, and psychiatry. vol 80. issue 5. 2009-05-08. PMID:19359288. |
ethanol is a well-established cerebellar toxin, resulting in purkinje cell loss. |
2009-05-08 |
2023-08-12 |
Not clear |
| Amor Belmeguenai, Paolo Botta, John T Weber, Mario Carta, Martijn De Ruiter, Chris I De Zeeuw, C Fernando Valenzuela, Christian Hanse. Alcohol impairs long-term depression at the cerebellar parallel fiber-Purkinje cell synapse. Journal of neurophysiology. vol 100. issue 6. 2009-04-23. PMID:18922952. |
it has previously been shown that ethanol modulates inhibitory transmission in the cerebellum and affects synaptic transmission and plasticity at excitatory climbing fiber (cf) to purkinje cell synapses. |
2009-04-23 |
2023-08-12 |
rat |
| Amor Belmeguenai, Paolo Botta, John T Weber, Mario Carta, Martijn De Ruiter, Chris I De Zeeuw, C Fernando Valenzuela, Christian Hanse. Alcohol impairs long-term depression at the cerebellar parallel fiber-Purkinje cell synapse. Journal of neurophysiology. vol 100. issue 6. 2009-04-23. PMID:18922952. |
however, it has not been examined thus far how acute ethanol application affects long-term depression (ltd) and long-term potentiation (ltp) at excitatory parallel fiber (pf) to purkinje cell synapses, which are assumed to mediate forms of cerebellar motor learning. |
2009-04-23 |
2023-08-12 |
rat |
| Rajiv M Agashiwala, Elan D Louis, Patrick R Hof, Daniel P Per. A novel approach to non-biased systematic random sampling: a stereologic estimate of Purkinje cells in the human cerebellum. Brain research. vol 1236. 2009-04-16. PMID:18725208. |
in an effort to quantify purkinje cells in association with certain neurodegenerative disorders, we developed a new method for stereologic sampling of the cerebellar cortex, involving calculating the volume of the cerebellar tissues, identifying and isolating the purkinje cell layer and using this information to extrapolate non-biased systematic sampling data to estimate the total number of purkinje cells in the tissues. |
2009-04-16 |
2023-08-12 |
human |
| Barbara Buccinnà, Marco Piccinini, Alessandro Prinetti, Federica Scandroglio, Simona Prioni, Manuela Valsecchi, Barbara Votta, Silvia Grifoni, Elisa Lupino, Cristina Ramondetti, Edward H Schuchman, Maria Teresa Giordana, Sandro Sonnino, Maria Teresa Rinaud. Alterations of myelin-specific proteins and sphingolipids characterize the brains of acid sphingomyelinase-deficient mice, an animal model of Niemann-Pick disease type A. Journal of neurochemistry. vol 109. issue 1. 2009-04-13. PMID:19187445. |
npd-a patients develop progressive neurodegeneration including cerebral and cerebellar atrophy, relevant purkinje cell and myelin deficiency with death within 3 years. |
2009-04-13 |
2023-08-12 |
mouse |
| Catherine M Gliddon, Zongjun Shao, Jillian L LeMaistre, Christopher M Anderso. Cellular distribution of the neutral amino acid transporter subtype ASCT2 in mouse brain. Journal of neurochemistry. vol 108. issue 2. 2009-04-08. PMID:19012749. |
in cerebellum both purkinje cell bodies and dendrites were positive for asct2 immunoreactivity. |
2009-04-08 |
2023-08-12 |
mouse |
| Tomoaki Kuroyanagi, Marie Yokoyama, Tomoo Hiran. Postsynaptic glutamate receptor delta family contributes to presynaptic terminal differentiation and establishment of synaptic transmission. Proceedings of the National Academy of Sciences of the United States of America. vol 106. issue 12. 2009-04-08. PMID:19258455. |
in mutant mice deficient in the glutamate receptor delta2 subunit (delta2), the number of synapses between granule neurons (gns) and a purkinje neuron (pn) in the cerebellum is reduced. |
2009-04-08 |
2023-08-12 |
mouse |
| Joelle Alcock, James Lowe, Tim England, Philip Bath, Virginie Sottil. Expression of Sox1, Sox2 and Sox9 is maintained in adult human cerebellar cortex. Neuroscience letters. vol 450. issue 2. 2009-03-24. PMID:19061938. |
in the mouse, expression of sox1, sox2 and sox9 genes has recently been reported outside of these recognised nsc niches, in the purkinje cell layer of the adult cerebellum. |
2009-03-24 |
2023-08-12 |
mouse |