| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Peter L Oliver, David A Keays, Kay E Davie. Behavioural characterisation of the robotic mouse mutant. Behavioural brain research. vol 181. issue 2. 2007-08-16. PMID:17532061. |
interestingly, spontaneous alternation testing in a t-maze was not significantly affected in robotic mice, unlike other ataxic mutants with more rapid and extensive cerebellar degeneration; robotic therefore provides an opportunity to investigate the necessity of specific purkinje cell populations for various behavioural tasks. |
2007-08-16 |
2023-08-12 |
mouse |
| D B Cameron, L Galas, Y Jiang, E Raoult, D Vaudry, H Komur. Cerebellar cortical-layer-specific control of neuronal migration by pituitary adenylate cyclase-activating polypeptide. Neuroscience. vol 146. issue 2. 2007-08-15. PMID:17383102. |
interestingly, in the cerebellar slices of p10 mice, application of exogenous pacap significantly inhibited granule cell migration in the external granular layer (egl) and molecular layer (ml), but failed to alter the movement in the purkinje cell layer (pcl) and internal granular layer (igl). |
2007-08-15 |
2023-08-12 |
mouse |
| Yasuhiro Nakamura, Yonehiro Kanemura, Tomiko Yamada, Yasuo Sugita, Koichi Higaki, Munehiko Yamamoto, Mitsuhiko Takahashi, Mami Yamasak. D2-40 antibody immunoreactivity in developing human brain, brain tumors and cultured neural cells. Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc. vol 19. issue 7. 2007-08-08. PMID:16648867. |
in the developing cerebellum, positive d2-40 immunoreactivity was found in the external granular layer particularly of the outer portion and the purkinje cell layer as well as meninges. |
2007-08-08 |
2023-08-12 |
human |
| Katsunori Sasahara, Hanako Shikimi, Shogo Haraguchi, Hirotaka Sakamoto, Shin-ichiro Honda, Nobuhiro Harada, Kazuyoshi Tsutsu. Mode of action and functional significance of estrogen-inducing dendritic growth, spinogenesis, and synaptogenesis in the developing Purkinje cell. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 28. 2007-08-07. PMID:17626201. |
estradiol may be involved in cerebellar neuronal circuit formation through promoting neuronal growth and neuronal synaptic contact, because the purkinje cell expresses estrogen receptor-beta (erbeta). |
2007-08-07 |
2023-08-12 |
mouse |
| Suzanne F C Miller, Kristen Summerhurst, Annette E Rünker, Géraldine Kerjan, Roland H Friedel, Alain Chédotal, Paula Murphy, Kevin J Mitchel. Expression of Plxdc2/TEM7R in the developing nervous system of the mouse. Gene expression patterns : GEP. vol 7. issue 5. 2007-07-30. PMID:17280871. |
plxdc2-betageo expression is particularly strong in the developing purkinje cell layer, especially in the posterior half of the cerebellum. |
2007-07-30 |
2023-08-12 |
mouse |
| Javier F Medina, Stephen G Lisberge. Variation, signal, and noise in cerebellar sensory-motor processing for smooth-pursuit eye movements. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 25. 2007-07-19. PMID:17581971. |
to ask how neural signal and noise are processed in the brain during sensory-motor behavior, we have evaluated the trial-by-trial variation of purkinje cell (pc) activity in the floccular complex of the cerebellum, an intermediate stage in the neural circuit for smooth-pursuit eye movements. |
2007-07-19 |
2023-08-12 |
Not clear |
| Christopher J Martyniuk, Rosalie Awad, Rachel Hurley, Thomas E Finger, Vance L Trudea. Glutamic acid decarboxylase 65, 67, and GABA-transaminase mRNA expression and total enzyme activity in the goldfish (Carassius auratus) brain. Brain research. vol 1147. 2007-07-16. PMID:17362888. |
transcripts for gad65, gad67, and gaba-t were detected throughout the brain and were detected largely in the medial and ventral regions of the telencephalon, nucleus preopticus, nucleus recessus lateralis of the hypothalamus, and purkinje cell layer of the cerebellum. |
2007-07-16 |
2023-08-12 |
human |
| Bruce E McKay, Jordan D T Engbers, W Hamish Mehaffey, Grant R J Gordon, Michael L Molineux, Jaideep S Bains, Ray W Turne. Climbing fiber discharge regulates cerebellar functions by controlling the intrinsic characteristics of purkinje cell output. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17267759. |
climbing fiber discharge regulates cerebellar functions by controlling the intrinsic characteristics of purkinje cell output. |
2007-07-10 |
2023-08-12 |
rat |
| Bruce E McKay, Jordan D T Engbers, W Hamish Mehaffey, Grant R J Gordon, Michael L Molineux, Jaideep S Bains, Ray W Turne. Climbing fiber discharge regulates cerebellar functions by controlling the intrinsic characteristics of purkinje cell output. Journal of neurophysiology. vol 97. issue 4. 2007-07-10. PMID:17267759. |
in rat cerebellar slices, we show that cf discharge presented at physiological frequencies substantially modifies the frequency and pattern of purkinje cell spike output in vitro. |
2007-07-10 |
2023-08-12 |
rat |
| Wolfgang Mittmann, Michael Häusse. Linking synaptic plasticity and spike output at excitatory and inhibitory synapses onto cerebellar Purkinje cells. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 21. 2007-06-22. PMID:17522301. |
thus, the net effect of cf-triggered plasticity on purkinje cell output depends on the balance of excitation and feedforward inhibition and can paradoxically increase cerebellar output, contrary to current theories of cerebellar motor learning. |
2007-06-22 |
2023-08-12 |
Not clear |
| R Lalonde, C Straziell. Spontaneous and induced mouse mutations with cerebellar dysfunctions: behavior and neurochemistry. Brain research. vol 1140. 2007-06-01. PMID:16499884. |
grid2(lc) (lurcher), grid2(ho) (hot-foot), rora(sg) (staggerer), nr (nervous), agtpbp1(pcd) (purkinje cell degeneration), reln(rl) (reeler), and girk2(wv) (weaver) are spontaneous mutations with cerebellar atrophy, ataxia, and deficits in motor coordination tasks requiring balance and equilibrium. |
2007-06-01 |
2023-08-12 |
mouse |
| Jeffrey A Kleim, Julie A Markham, Kapil Vij, Jennifer L Freese, David H Ballard, William T Greenoug. Motor learning induces astrocytic hypertrophy in the cerebellar cortex. Behavioural brain research. vol 178. issue 2. 2007-05-21. PMID:17257689. |
unbiased stereological techniques were used to determine that ac animals had a significantly greater volume of astrocytes per purkinje cell in the cerebellar paramedian lobule than the mc animals, a difference which was reduced (and not statistically detectable) among animals in the delay condition. |
2007-05-21 |
2023-08-12 |
rat |
| Ruth M Empson, Molly L Garside, Thomas Knöpfe. Plasma membrane Ca2+ ATPase 2 contributes to short-term synapse plasticity at the parallel fiber to Purkinje neuron synapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 14. 2007-05-02. PMID:17409239. |
here, we provide direct functional evidence for the influence of presynaptic pmca2-mediated ca2+ extrusion for short-term plasticity at cerebellar parallel fiber to purkinje neuron synapses. |
2007-05-02 |
2023-08-12 |
mouse |
| Maria Christensson, Jonas Broman, Martin Garwic. Time course of cerebellar morphological development in postnatal ferrets: ontogenetic and comparative perspectives. The Journal of comparative neurology. vol 501. issue 6. 2007-04-26. PMID:17311324. |
overall cerebellar size, foliation, and thickness of cortical layers were quantified and purkinje cell morphology was characterized at 24 timepoints in ferrets from postnatal day (p)1 to p63. |
2007-04-26 |
2023-08-12 |
rat |
| Dan-Anders Jirenhed, Fredrik Bengtsson, Germund Hesslo. Acquisition, extinction, and reacquisition of a cerebellar cortical memory trace. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 27. issue 10. 2007-04-09. PMID:17344387. |
we demonstrate that paired peripheral forelimb and periocular stimulation, as well as paired direct stimulation of cerebellar afferent pathways (mossy and climbing fibers) consistently causes a gradual acquisition of an inhibitory response in purkinje cell simple spike firing. |
2007-04-09 |
2023-08-12 |
Not clear |
| Emmanuelle Bitoun, Peter L Oliver, Kay E Davie. The mixed-lineage leukemia fusion partner AF4 stimulates RNA polymerase II transcriptional elongation and mediates coordinated chromatin remodeling. Human molecular genetics. vol 16. issue 1. 2007-04-03. PMID:17135274. |
af4 gene, frequently translocated with mixed-lineage leukemia (mll) in childhood acute leukemia, encodes a putative transcriptional activator of the af4/laf4/fmr2 (alf) protein family previously implicated in lymphopoiesis and purkinje cell function in the cerebellum. |
2007-04-03 |
2023-08-12 |
mouse |
| Olga Krysko, Leen Hulshagen, Anneleen Janssen, Günter Schütz, Rüdiger Klein, Melina De Bruycker, Marc Espeel, Pierre Gressens, Myriam Bae. Neocortical and cerebellar developmental abnormalities in conditions of selective elimination of peroxisomes from brain or from liver. Journal of neuroscience research. vol 85. issue 1. 2007-03-21. PMID:17075904. |
major abnormalities were seen in the formation of the cerebellum of these liver knockout mice, including hypotrophy, impaired foliation, a delay of granule cell migration, increased cell death, and stunted purkinje cell arborization. |
2007-03-21 |
2023-08-12 |
mouse |
| Marylka Uusisaari, Kunihiko Obata, Thomas Knöpfe. Morphological and electrophysiological properties of GABAergic and non-GABAergic cells in the deep cerebellar nuclei. Journal of neurophysiology. vol 97. issue 1. 2007-03-09. PMID:17093116. |
the deep cerebellar nuclei (dcn) integrate inputs from the brain stem, the inferior olive, and the spinal cord with purkinje cell output from cerebellar cortex and provide the major output of the cerebellum. |
2007-03-09 |
2023-08-12 |
mouse |
| Srinivasan Kanumilli, Elizabeth W Tringham, C Elizabeth Payne, Jonathan R B Dupere, Kanamarlapudi Venkateswarlu, Maria M Usowic. Alternative splicing generates a smaller assortment of CaV2.1 transcripts in cerebellar Purkinje cells than in the cerebellum. Physiological genomics. vol 24. issue 2. 2007-03-06. PMID:16278278. |
single cell rt-pcr reveals that each individual cerebellar purkinje neuron also expresses multiple alternative cav2.1 transcripts, but the assortment is smaller than in the cerebellum. |
2007-03-06 |
2023-08-12 |
mouse |
| Dan Gincel, Melissa R Regan, Lin Jin, Andrew M Watkins, Dwight E Bergles, Jeffrey D Rothstei. Analysis of cerebellar Purkinje cells using EAAT4 glutamate transporter promoter reporter in mice generated via bacterial artificial chromosome-mediated transgenesis. Experimental neurology. vol 203. issue 1. 2007-02-23. PMID:17022974. |
cerebellar organotypic slice cultures prepared from bac transgenic mice provided a unique reagent to study transporter and purkinje cell expression and regulation in living tissue. |
2007-02-23 |
2023-08-12 |
mouse |