| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Takuji Igarashi, Matthew B Potts, Linda J Noble-Haeusslei. Injury severity determines Purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury. Experimental neurology. vol 203. issue 1. 2007-02-23. PMID:17045589. |
injury severity determines purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury. |
2007-02-23 |
2023-08-12 |
rat |
| Takuji Igarashi, Matthew B Potts, Linda J Noble-Haeusslei. Injury severity determines Purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury. Experimental neurology. vol 203. issue 1. 2007-02-23. PMID:17045589. |
we have previously shown cerebellar vulnerability, as demonstrated by purkinje cell loss and microglial activation, after fluid percussion brain injury. |
2007-02-23 |
2023-08-12 |
rat |
| Takuji Igarashi, Matthew B Potts, Linda J Noble-Haeusslei. Injury severity determines Purkinje cell loss and microglial activation in the cerebellum after cortical contusion injury. Experimental neurology. vol 203. issue 1. 2007-02-23. PMID:17045589. |
similarly, there was a distinctive pattern of purkinje cell loss and microglial activation in the cerebellar vermis that varied with injury severity. |
2007-02-23 |
2023-08-12 |
rat |
| Yasushi Iwasaki, Masahiro Iijima, Seigo Kimura, Mari Yoshida, Yoshio Hashizume, Masahito Yamada, Tetsuyuki Kitamoto, Gen Sobu. Autopsy case of sporadic Creutzfeldt-Jakob disease presenting with signs suggestive of brainstem and spinal cord involvement. Neuropathology : official journal of the Japanese Society of Neuropathology. vol 26. issue 6. 2007-02-12. PMID:17203592. |
in the cerebellum, although the granular, molecular and purkinje cell layers were well preserved from neuronal loss and gliosis, prp deposition was marked in the molecular and granular cell layers. |
2007-02-12 |
2023-08-12 |
Not clear |
| b' Jos\\xc3\\xa9 Gazulla, Mari A Tintor\\xc3\\xa. The P/Q-type voltage-dependent calcium channel as pharmacological target in spinocerebellar ataxia type 6: gabapentin and pregabalin may be of therapeutic benefit. Medical hypotheses. vol 68. issue 1. 2007-01-30. PMID:16899342.' |
their highest levels of expression are found in the purkinje cell layer of the cerebellum, and in the hippocampus. |
2007-01-30 |
2023-08-12 |
xenopus_laevis |
| Cristina Martins-Silva, Lucimar Teodoro Ferreira, Michel Cyr, Janaina Koenen, Diane Ramires Fernandes, Natalia Rodrigues Carvalho, Caroline Batista Franco Ribeiro, Sébastien Marion, Carlos Chavez-Olortegui, Marco Antonio Maximo Prado, Vania Ferreira Prad. A rat homologue of CED-6 is expressed in neurons and interacts with clathrin. Brain research. vol 1119. issue 1. 2007-01-26. PMID:17007823. |
ced-6 immunoreactivity was also investigated using immunohistochemistry analysis and it was found in several brain regions, being particularly strong in the cell body of some groups of neurons such as purkinje cell layer of cerebellum, and pyramidal cells of the hippocampal formation and also in epithelial cells from the choroid plexus. |
2007-01-26 |
2023-08-12 |
rat |
| H-B Yuan, Y Huang, S Zheng, Z Zu. Hypothermic preconditioning reduces Purkinje cell death possibly by preventing the over-expression of inducible nitric oxide synthase in rat cerebellar slices after an in vitro simulated ischemia. Neuroscience. vol 142. issue 2. 2007-01-23. PMID:16890370. |
hypothermic preconditioning reduces purkinje cell death possibly by preventing the over-expression of inducible nitric oxide synthase in rat cerebellar slices after an in vitro simulated ischemia. |
2007-01-23 |
2023-08-12 |
rat |
| Kazuyoshi Tsutsu. Biosynthesis, mode of action and functional significance of neurosteroids in the developing Purkinje cell. The Journal of steroid biochemistry and molecular biology. vol 102. issue 1-5. 2007-01-23. PMID:17113981. |
recently, we have demonstrated that the purkinje cell, a cerebellar neuron, is a major site for neurosteroid formation in a variety of vertebrates. |
2007-01-23 |
2023-08-12 |
Not clear |
| Kazuyoshi Tsutsu. Biosynthesis, mode of action and functional significance of neurosteroids in the developing Purkinje cell. The Journal of steroid biochemistry and molecular biology. vol 102. issue 1-5. 2007-01-23. PMID:17113981. |
in mammals, the purkinje cell actively synthesizes progesterone de novo from cholesterol during neonatal life, when cerebellar neuronal circuit formation occurs. |
2007-01-23 |
2023-08-12 |
Not clear |
| A Ardeshiri, M H Kelley, I P Korner, P D Hurn, P S Herso. Mechanism of progesterone neuroprotection of rat cerebellar Purkinje cells following oxygen-glucose deprivation. The European journal of neuroscience. vol 24. issue 9. 2007-01-19. PMID:17100844. |
the survival of rat purkinje cell (pcs) cerebellar cultures was used to test the hypothesis that progesterone is protective against oxygen-glucose deprivation through potentiation of gaba(a) receptor activity. |
2007-01-19 |
2023-08-12 |
rat |
| Jacob Jelsing, Hans Jørgen G Gundersen, Rune Nielsen, Ralf Hemmingsen, Bente Pakkenber. The postnatal development of cerebellar Purkinje cells in the Göttingen minipig estimated with a new stereological sampling technique--the vertical bar fractionator. Journal of anatomy. vol 209. issue 3. 2007-01-18. PMID:16928201. |
the study demonstrates that a pronounced postnatal neurogenesis in purkinje cell number and perikaryon volume is part of the growth and development of the cerebellum in the göttingen minipig. |
2007-01-18 |
2023-08-12 |
human |
| Y Hellenbroich, K Gierga, E Reusche, E Schwinger, T Deller, R A I de Vos, C Zühlke, U Rü. Spinocerebellar ataxia type 4 (SCA4): Initial pathoanatomical study reveals widespread cerebellar and brainstem degeneration. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 7. 2007-01-05. PMID:16362839. |
severe neuronal loss was seen in the purkinje cell layer of the cerebellum, in the cerebellar fastigial nucleus, in the red, trochlear, lateral vestibular, and lateral reticular nuclei, the reticulotegmental nucleus of the pons, and the nucleus of roller. |
2007-01-05 |
2023-08-12 |
Not clear |
| Anna La Torre, José Antonio del Rio, Eduardo Soriano, Jesús Mariano Ureñ. Expression pattern of ACK1 tyrosine kinase during brain development in the mouse. Gene expression patterns : GEP. vol 6. issue 8. 2006-12-20. PMID:16750431. |
during development, several areas showed an increase in ack1 expression, especially the dentate gyrus and ca3 in the hippocampus, layer v in the neocortex, and the purkinje cell layer in the cerebellum. |
2006-12-20 |
2023-08-12 |
mouse |
| Daniver Morales, Mary E Hatte. Molecular markers of neuronal progenitors in the embryonic cerebellar anlage. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 47. 2006-12-15. PMID:17122047. |
examination of gene expression patterns in several hundred lines of egfp-bac (bacterial artificial chromosome) transgenic mice in the gensat project revealed numerous genes with restricted expression in cerebellar progenitor populations, including genes specific for cerebellar nuclear precursors and purkinje cell precursors. |
2006-12-15 |
2023-08-12 |
mouse |
| Francisco López-Muñoz, Jesús Boya, Cecilio Alam. Neuron theory, the cornerstone of neuroscience, on the centenary of the Nobel Prize award to Santiago Ramón y Cajal. Brain research bulletin. vol 70. issue 4-6. 2006-12-05. PMID:17027775. |
in the first issue of the revista trimestral de histología normal y patológica (may, 1888), cajal presented the definitive evidence underpinning neuron theory, thanks to staining of the axon of the small, star-shaped cells of the molecular layer of the cerebellum of birds, whose collaterals end up surrounding the purkinje cell bodies, in the form of baskets or nests. |
2006-12-05 |
2023-08-12 |
Not clear |
| Sara K Custer, Gwenn A Garden, Nishi Gill, Udo Rueb, Randell T Libby, Christian Schultz, Stephan J Guyenet, Thomas Deller, Lesnick E Westrum, Bryce L Sopher, Albert R La Spad. Bergmann glia expression of polyglutamine-expanded ataxin-7 produces neurodegeneration by impairing glutamate transport. Nature neuroscience. vol 9. issue 10. 2006-11-14. PMID:16936724. |
we considered the possibility that glial dysfunction leads to purkinje cell degeneration, and generated mice that express ataxin-7 in bergmann glia of the cerebellum with the gfa2 promoter. |
2006-11-14 |
2023-08-12 |
mouse |
| Isao Nagata, Katsuhiko Ono, Akio Kawana, Junko Kimura-Kurod. Aligned neurite bundles of granule cells regulate orientation of Purkinje cell dendrites by perpendicular contact guidance in two-dimensional and three-dimensional mouse cerebellar cultures. The Journal of comparative neurology. vol 499. issue 2. 2006-11-14. PMID:16977618. |
aligned neurite bundles of granule cells regulate orientation of purkinje cell dendrites by perpendicular contact guidance in two-dimensional and three-dimensional mouse cerebellar cultures. |
2006-11-14 |
2023-08-12 |
mouse |
| Stephen Crimmins, Youngam Jin, Crystal Wheeler, Alexis K Huffman, Carlene Chapman, Lynn E Dobrunz, Alan Levey, Kevin A Roth, Julie A Wilson, Scott M Wilso. Transgenic rescue of ataxia mice with neuronal-specific expression of ubiquitin-specific protease 14. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 26. issue 44. 2006-11-14. PMID:17079671. |
however, the axj-rescued mice still displayed the purkinje cell axonal swellings that are seen in the axj mice, indicating that this cerebellar alteration is not the primary cause of the axj movement disorders. |
2006-11-14 |
2023-08-12 |
mouse |
| Stephen I Levin, Zayd M Khaliq, Teresa K Aman, Tina M Grieco, Jennifer A Kearney, Indira M Raman, Miriam H Meisle. Impaired motor function in mice with cell-specific knockout of sodium channel Scn8a (NaV1.6) in cerebellar purkinje neurons and granule cells. Journal of neurophysiology. vol 96. issue 2. 2006-11-08. PMID:16687615. |
in cerebellar slices, purkinje cell spontaneous and maximal firing rates were reduced 10-fold and twofold relative to control in purkinje ko and double ko but not granule ko mice. |
2006-11-08 |
2023-08-12 |
mouse |
| R H Joho, C Street, S Matsushita, T Knöpfe. Behavioral motor dysfunction in Kv3-type potassium channel-deficient mice. Genes, brain, and behavior. vol 5. issue 6. 2006-11-01. PMID:16923152. |
the lack of kv3.1 channel subunits is mainly responsible for the constitutively increased locomotor activity and for sleep loss, whereas the absence of kv3.3 subunits affects cerebellar function, in particular purkinje cell discharges and olivocerebellar system properties (mcmahon et al. |
2006-11-01 |
2023-08-12 |
mouse |