| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T A Reader, J Sénéca. Topology of ionotropic glutamate receptors in brains of heterozygous and homozygous weaver mutant mice. Synapse (New York, N.Y.). vol 42. issue 4. 2002-01-10. PMID:11746720. |
in weaver mice, mutation of a g-protein inwardly rectifying k(+) channel leads to a cerebellar developmental anomaly characterized by granule and purkinje cell loss and, in addition, degeneration of dopaminergic neurons. |
2002-01-10 |
2023-08-12 |
mouse |
| S M Jenkins, V Bennet. Ankyrin-G coordinates assembly of the spectrin-based membrane skeleton, voltage-gated sodium channels, and L1 CAMs at Purkinje neuron initial segments. The Journal of cell biology. vol 155. issue 5. 2002-01-08. PMID:11724816. |
betaiv spectrin, nav1.6, and l1 cams are not clustered in adult purkinje neuron initial segments of mice lacking cerebellar ankyrin-g. |
2002-01-08 |
2023-08-12 |
mouse |
| M Taniguchi, Y Shinoda, H Ninomiya, M T Vanier, K Ohn. Sites and temporal changes of gangliosides GM1/GM2 storage in the Niemann-Pick disease type C mouse brain. Brain & development. vol 23. issue 6. 2002-01-03. PMID:11578853. |
anti-gm1 gave positive staining of the hippocampus, thalamus, cerebellar molecular and purkinje cell layers in the 3-week old npc mouse brain and in general, the staining progressively diminished in an age-dependent manner. |
2002-01-03 |
2023-08-12 |
mouse |
| C Armstrong, R Hawke. Selective Purkinje cell ectopia in the cerebellum of the weaver mouse. The Journal of comparative neurology. vol 439. issue 2. 2001-12-07. PMID:11596045. |
selective purkinje cell ectopia in the cerebellum of the weaver mouse. |
2001-12-07 |
2023-08-12 |
mouse |
| C Armstrong, R Hawke. Selective Purkinje cell ectopia in the cerebellum of the weaver mouse. The Journal of comparative neurology. vol 439. issue 2. 2001-12-07. PMID:11596045. |
we therefore conclude that specific purkinje cell clusters in the wv/wv cerebellum fail to disperse and that this ectopia contributes to the topographical abnormalities. |
2001-12-07 |
2023-08-12 |
mouse |
| A Abdel-Rahman, A K Shetty, M B Abou-Doni. Subchronic dermal application of N,N-diethyl m-toluamide (DEET) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and Purkinje neuron loss in the cerebellum. Experimental neurology. vol 172. issue 1. 2001-12-05. PMID:11681848. |
subchronic dermal application of n,n-diethyl m-toluamide (deet) and permethrin to adult rats, alone or in combination, causes diffuse neuronal cell death and cytoskeletal abnormalities in the cerebral cortex and the hippocampus, and purkinje neuron loss in the cerebellum. |
2001-12-05 |
2023-08-12 |
rat |
| S E Martínez, J Vaglenova, J Sabrià, M C Martínez, J Farrés, X Paré. Distribution of alcohol dehydrogenase mRNA in the rat central nervous system. Consequences for brain ethanol and retinoid metabolism. European journal of biochemistry. vol 268. issue 19. 2001-12-04. PMID:11589695. |
adh1 mrna was found in the granular and purkinje cell layers of cerebellum, in the pyramidal and granule cells of the hippocampal formation and in some cell types of cerebral cortex. |
2001-12-04 |
2023-08-12 |
rat |
| V Deiss, M Dubois, R Lalonde, C Straziell. Cytochrome oxidase activity in the olfactory system of staggerer mutant mice. Brain research. vol 910. issue 1-2. 2001-10-25. PMID:11489262. |
in addition to the well-studied gene expression in the cerebellum causing massive primary purkinje cell loss, the roralpha gene is also expressed in the thalamus and the olfactory bulb. |
2001-10-25 |
2023-08-12 |
mouse |
| Rina-Susilowati, A A Jusuf, H Sakagami, S Kikkawa, H Kondo, Y Minami, T Terashim. Distribution of Ca(2+)/calmodulin-dependent protein kinase I beta 2 in the central nervous system of the rat. Brain research. vol 911. issue 1. 2001-10-11. PMID:11489438. |
quite strong staining could also be observed in almost all of the neurons in the neocortex, hippocampus, amygdala, hypothalamus, brainstem and cerebellum, including the nuclei of the cranial nerves and purkinje cell layer of the cerebellar cortex which was not clearly detected in the previous in situ hybridization study. |
2001-10-11 |
2023-08-12 |
mouse |
| C W Anderso. Anatomical evidence for brainstem circuits mediating feeding motor programs in the leopard frog, Rana pipiens. Experimental brain research. vol 140. issue 1. 2001-10-11. PMID:11500793. |
results presented here suggest an additional pathway from the hypoglossal motor nuclei to the cerebellar nucleus as well as an afferent projection from the peripheral hypoglossal nerve to the purkinje cell layer of the cerebellar cortex. |
2001-10-11 |
2023-08-12 |
Not clear |
| A Plagge, L Sendtner-Voelderndorff, P Sirim, J Freigang, C Rader, P Sonderegger, T Brümmendor. The contactin-related protein FAR-2 defines purkinje cell clusters and labels subpopulations of climbing fibers in the developing cerebellum. Molecular and cellular neurosciences. vol 18. issue 1. 2001-09-27. PMID:11461156. |
the contactin-related protein far-2 defines purkinje cell clusters and labels subpopulations of climbing fibers in the developing cerebellum. |
2001-09-27 |
2023-08-12 |
chicken |
| Y Arai, T Ijuin, M Itoh, T Takenawa, S Takashima, L E Becke. Developmental changes of synaptojanin expression in the human cerebrum and cerebellum. Brain research. Developmental brain research. vol 129. issue 1. 2001-09-06. PMID:11454408. |
in the fetal cerebellum, synaptojanin immunoreactivity was localized in the external granular cell layer, purkinje cell layer neuropil, cytoplasm of purkinje cells and internal granular cells. |
2001-09-06 |
2023-08-12 |
human |
| Y Arai, T Ijuin, M Itoh, T Takenawa, S Takashima, L E Becke. Developmental changes of synaptojanin expression in the human cerebrum and cerebellum. Brain research. Developmental brain research. vol 129. issue 1. 2001-09-06. PMID:11454408. |
after birth, the synaptojanin immunoreactivity of cortical neurons in the cerebrum, purkinje cell layer neuropil, and internal granular cells and purkinje cells in the cerebellum increased and reached a plateau after 11 years of age. |
2001-09-06 |
2023-08-12 |
human |
| E Carro, J L Trejo, S Busiguina, I Torres-Alema. Circulating insulin-like growth factor I mediates the protective effects of physical exercise against brain insults of different etiology and anatomy. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466439. |
laboratory rodents were submitted to treadmill running (1 km/d) either before or after neurotoxin insult of the hippocampus (domoic acid) or the brainstem (3-acetylpyridine) or along progression of inherited neurodegeneration affecting the cerebellum (purkinje cell degeneration). |
2001-08-16 |
2023-08-12 |
mouse |
| J Goossens, H Daniel, A Rancillac, J van der Steen, J Oberdick, F Crépel, C I De Zeeuw, M A Fren. Expression of protein kinase C inhibitor blocks cerebellar long-term depression without affecting Purkinje cell excitability in alert mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466453. |
expression of protein kinase c inhibitor blocks cerebellar long-term depression without affecting purkinje cell excitability in alert mice. |
2001-08-16 |
2023-08-12 |
mouse |
| J Goossens, H Daniel, A Rancillac, J van der Steen, J Oberdick, F Crépel, C I De Zeeuw, M A Fren. Expression of protein kinase C inhibitor blocks cerebellar long-term depression without affecting Purkinje cell excitability in alert mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 21. issue 15. 2001-08-16. PMID:11466453. |
we conclude that cerebellar ltd is probably one of the major mechanisms underlying motor learning, but that deficits in ltd induction and motor learning as observed in the l7-pkci mutants may only be reflected in differences of the purkinje cell signals during and/or directly after training. |
2001-08-16 |
2023-08-12 |
mouse |
| S H Fatemi, A R Halt, J M Stary, G M Realmuto, M Jalali-Mousav. Reduction in anti-apoptotic protein Bcl-2 in autistic cerebellum. Neuroreport. vol 12. issue 5. 2001-08-09. PMID:11303762. |
neurohistologic findings have shown purkinje cell depletion and atrophy in the cerebellum of autistic subjects. |
2001-08-09 |
2023-08-12 |
human |
| E Beierbach, C Park, S L Ackerman, D Goldowitz, R Hawke. Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). The Journal of comparative neurology. vol 436. issue 1. 2001-07-26. PMID:11413545. |
abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). |
2001-07-26 |
2023-08-12 |
mouse |
| E Beierbach, C Park, S L Ackerman, D Goldowitz, R Hawke. Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). The Journal of comparative neurology. vol 436. issue 1. 2001-07-26. PMID:11413545. |
during cerebellar development, purkinje cell bands are formed through the rostrocaudal dispersal of embryonic clusters, triggered primarily by a reelin-dependent signaling pathway. |
2001-07-26 |
2023-08-12 |
mouse |
| E Beierbach, C Park, S L Ackerman, D Goldowitz, R Hawke. Abnormal dispersion of a purkinje cell subset in the mouse mutant cerebellar deficient folia (cdf). The Journal of comparative neurology. vol 436. issue 1. 2001-07-26. PMID:11413545. |
in the naturally occurring mouse mutant cerebellar deficient folia (cdf), there is a failure of purkinje cell dispersion that results in widespread purkinje cell ectopia in the adult. |
2001-07-26 |
2023-08-12 |
mouse |