| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Alexander S Brown, Pratap Meera, Gabe Quinones, Jessica Magri, Thomas S Otis, Stefan M Pulst, Anthony E Or. Receptor protein tyrosine phosphatases control Purkinje neuron firing. Cell cycle (Georgetown, Tex.). vol 19. issue 2. 2021-01-29. PMID:31876231. |
in this extra view we show that mtss1 inhibits sfk activity through the binding and inhibition of a subset of the rptp family members, and lowering rptp activity in cerebellar slices with peptide inhibitors increases the suppressed purkinje neuron basal firing rates seen in two different sca models. |
2021-01-29 |
2023-08-13 |
Not clear |
| Liam Argent, Friederike Winter, Imogen Prickett, Maria Carrasquero-Ordaz, Abby L Olsen, Holger Kramer, Eric Lancaster, Esther B E Becke. Caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates Purkinje cell morphology. The Journal of biological chemistry. vol 295. issue 36. 2021-01-27. PMID:32675284. |
caspr2 interacts with type 1 inositol 1,4,5-trisphosphate receptor in the developing cerebellum and regulates purkinje cell morphology. |
2021-01-27 |
2023-08-13 |
Not clear |
| Ruth Gussenhoven, Daan R M G Ophelders, Jeroen Dudink, Kay Pieterman, Martin Lammens, Robert W Mays, Luc J Zimmermann, Boris W Kramer, Tim G A M Wolfs, Reint K Jellem. Systemic multipotent adult progenitor cells protect the cerebellum after asphyxia in fetal sheep. Stem cells translational medicine. vol 10. issue 1. 2021-01-11. PMID:32985793. |
global hi caused marked cortical injury in the cerebellum, histologically indicated by disruption of cortical strata, impeded purkinje cell development, and decreased dendritic arborization. |
2021-01-11 |
2023-08-13 |
Not clear |
| Kazuyoshi Tsutsui, Shogo Haraguch. Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells. FASEB bioAdvances. vol 2. issue 3. 2021-01-10. PMID:32161904. |
the purkinje cell, a cerebellar neuron, was discovered as a major site of the biosynthesis of neurosteroids including sex steroids, such as progesterone, from cholesterol in the brain. |
2021-01-10 |
2023-08-13 |
Not clear |
| Kazuyoshi Tsutsui, Shogo Haraguch. Neuroprotective actions of cerebellar and pineal allopregnanolone on Purkinje cells. FASEB bioAdvances. vol 2. issue 3. 2021-01-10. PMID:32161904. |
allopregnanolone, a progesterone metabolite, is also synthesized in the cerebellum and acts on the purkinje cell to prevent cell death of this neuron. |
2021-01-10 |
2023-08-13 |
Not clear |
| G Jean Harry, Michelle J Hooth, Molly Vallant, Mamta Behl, Gregory S Travlos, James L Howard, Catherine J Price, Sandra McBride, Ron Mervis, Peter R Mouto. Developmental neurotoxicity of 3,3',4,4'-tetrachloroazobenzene with thyroxine deficit: Sensitivity of glia and dentate granule neurons in the absence of behavioral changes. Toxics. vol 2. issue 3. 2021-01-09. PMID:26029700. |
at 10 mg/kg/day, microglia showed less complex processes, unbiased stereology detected fewer hippocampal ca1 pyramidal neurons and dentate granule neurons (gc) and golgi staining of the cerebellum showed diminished purkinje cell dendritic arbor. |
2021-01-09 |
2023-08-13 |
rat |
| Zhilai Yang, Na Chen, Rongjing Ge, Hao Qian, Jin-Hui Wan. Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum. Oncotarget. vol 8. issue 42. 2021-01-09. PMID:29069799. |
functional compatibility between purkinje cell axon branches and their target neurons in the cerebellum. |
2021-01-09 |
2023-08-13 |
Not clear |
| Zhilai Yang, Na Chen, Rongjing Ge, Hao Qian, Jin-Hui Wan. Functional compatibility between Purkinje cell axon branches and their target neurons in the cerebellum. Oncotarget. vol 8. issue 42. 2021-01-09. PMID:29069799. |
we have examined this hypothesis by using electrophysiological method in the cerebellum, in which the main axon of purkinje cell projected to deep nucleus cells and the recurrent axons innervated the adjacent purkinje cells. |
2021-01-09 |
2023-08-13 |
Not clear |
| Jesse L Barnes, Claudia Mohr, Caitlin R Ritchey, Chloe M Erikson, Hiroko Shiina, David J Ross. Developmentally Transient CB1Rs on Cerebellar Afferents Suppress Afferent Input, Downstream Synaptic Excitation, and Signaling to Migrating Neurons. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 40. issue 32. 2021-01-04. PMID:32631938. |
we determined that, in the developing rodent cerebellar cortex (of both sexes), there is a transient window when the dominant brain cannabinoid receptor, cb1r, is expressed on afferent terminals instead of output neuron purkinje cell synapses that dominate the adult cerebellum. |
2021-01-04 |
2023-08-13 |
Not clear |
| Hyerin Song, Jung Woong Chu, Su Chan Park, Hyuntae Im, Il-Geun Park, Hyunkyung Kim, Ji Min Le. Isoform-Specific Lysine Methylation of RORα2 by SETD7 Is Required for Association of the TIP60 Coactivator Complex in Prostate Cancer Progression. International journal of molecular sciences. vol 21. issue 5. 2020-12-24. PMID:32120841. |
rorα was shown to regulate a broad array of physiological processes such as purkinje cell development in the cerebellum, circadian rhythm, lipid and bone metabolism, inhibition of inflammation, and anti-apoptosis. |
2020-12-24 |
2023-08-13 |
human |
| Kunihiko Yamashiro, Kei Hori, Esther S K Lai, Ryo Aoki, Kazumi Shimaoka, Nariko Arimura, Saki F Egusa, Asami Sakamoto, Manabu Abe, Kenji Sakimura, Takaki Watanabe, Naofumi Uesaka, Masanobu Kano, Mikio Hoshin. AUTS2 Governs Cerebellar Development, Purkinje Cell Maturation, Motor Function and Social Communication. iScience. vol 23. issue 12. 2020-12-12. PMID:33305180. |
auts2 governs cerebellar development, purkinje cell maturation, motor function and social communication. |
2020-12-12 |
2023-08-13 |
Not clear |
| Ching Serena Kao, Rebekah van Bruggen, Jihye Rachel Kim, Xiao Xiao Lily Chen, Cadia Chan, Jooyun Lee, Woo In Cho, Melody Zhao, Claudia Arndt, Katarina Maksimovic, Mashiat Khan, Qiumin Tan, Michael D Wilson, Jeehye Par. Selective neuronal degeneration in MATR3 S85C knock-in mouse model of early-stage ALS. Nature communications. vol 11. issue 1. 2020-11-24. PMID:33082323. |
matr3 s85c knock-in mice recapitulate behavioral and neuropathological features of early-stage als including motor impairment, muscle atrophy, neuromuscular junction defects, purkinje cell degeneration and neuroinflammation in the cerebellum and spinal cord. |
2020-11-24 |
2023-08-13 |
mouse |
| Yuanjun Luo, Takeru Onozato, Xuanjing Wu, Kazuma Sasamura, Kenji Sakimura, Izumi Sugihar. Dense projection of Stilling's nucleus spinocerebellar axons that convey tail proprioception to the midline area in lobule VIII of the mouse cerebellum. Brain structure & function. vol 225. issue 2. 2020-11-20. PMID:31955293. |
anterograde labeling of purkinje cell axons in this area showed terminals in the medial pole of the medial cerebellar nucleus. |
2020-11-20 |
2023-08-13 |
mouse |
| Antony Cougnoux, Mason Fellmeth, Tansy Gu, Cristin D Davidson, Alana L Gibson, William J Pavan, Forbes D Porte. Maternal immune activation modifies the course of Niemann-pick disease, type C1 in a gender specific manner. Molecular genetics and metabolism. vol 129. issue 2. 2020-11-12. PMID:31668555. |
studies in other mouse models of cerebellar ataxia have shown that developmental exposures lead to purkinje neuron degeneration later in life, suggesting that environmental exposures during development can impact cerebellar biology. |
2020-11-12 |
2023-08-13 |
mouse |
| Takagi Ryunosuke, Taiga Matsuda, Keiichiro Inagak. Roles of the Cerebellar Interneurons on Vestibulo-Ocular Reflex Motor Learning: A Computational Study. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2020. 2020-10-23. PMID:33018009. |
the cerebellum receives sensory and motor information via mossy and climbing fibers, and solely outputs motor-related activities from purkinje cell. |
2020-10-23 |
2023-08-13 |
Not clear |
| Alyssa Michelle Wilson, Richard Schalek, Adi Suissa-Peleg, Thouis R Jones, Seymour Knowles-Barley, Hanspeter Pfister, Jeff William Lichtma. Developmental Rewiring between Cerebellar Climbing Fibers and Purkinje Cells Begins with Positive Feedback Synapse Addition. Cell reports. vol 29. issue 9. 2020-10-20. PMID:31775050. |
during postnatal development, cerebellar climbing fibers alter their innervation strengths onto supernumerary purkinje cell targets, generating a one-to-few connectivity pattern in adulthood. |
2020-10-20 |
2023-08-13 |
mouse |
| T V Karelina, Yu D Stepanenko, P A Abushik, D A Sibarov, S M Antono. Downregulation of Purkinje Cell Activity by Modulators of Small Conductance Calcium-Activated Potassium Channels In Rat Cerebellum. Acta naturae. vol 8. issue 4. 2020-10-01. PMID:28050270. |
downregulation of purkinje cell activity by modulators of small conductance calcium-activated potassium channels in rat cerebellum. |
2020-10-01 |
2023-08-13 |
rat |
| Fredrick John Sei. Activity-Dependent Inhibitory Synaptogenesis in Cerebellar Cultures. Brain plasticity (Amsterdam, Netherlands). vol 1. issue 2. 2020-10-01. PMID:29765842. |
inhibitory synapses on purkinje cell somata in organotypic cerebellar cultures derived from newborn mice were increased after chronic exposure post explantation to agents that enhance neuronal activity. |
2020-10-01 |
2023-08-13 |
mouse |
| Fredrick John Sei. Activity-Dependent Inhibitory Synaptogenesis in Cerebellar Cultures. Brain plasticity (Amsterdam, Netherlands). vol 1. issue 2. 2020-10-01. PMID:29765842. |
the effect of endogenous neurotrophins was evaluated by continuously exposing cerebellar cultures to antibodies to bdnf and nt-4, which caused a significant reduction in the development of inhibitory purkinje cell axosomatic synapses. |
2020-10-01 |
2023-08-13 |
mouse |
| Gamze Altun, Suleyman Kaplan, Omur Gulsum Deniz, Suleyman Emre Kocacan, Sinan Canan, Devra Davis, Cafer Marango. Protective effects of melatonin and omega-3 on the hippocampus and the cerebellum of adult Wistar albino rats exposed to electromagnetic fields. Journal of microscopy and ultrastructure. vol 5. issue 4. 2020-10-01. PMID:30023259. |
significant purkinje cell loss was found in the cerebellum of emf group compared to the other (p < 0.01). |
2020-10-01 |
2023-08-13 |
rat |