| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Pengjun Wang, Chen Chen, Min Sha. Vincamine alleviates brain injury by attenuating neuroinflammation and oxidative damage in a mouse model of Parkinson's disease through the NF-κB and Nrf2/HO-1 signaling pathways. Journal of biochemical and molecular toxicology. vol 38. issue 5. 2024-04-17. PMID:38629493. |
parkinson's disease (pd) is a neurodegenerative disease featured by progressive loss of nigrostriatal dopaminergic neurons, the etiology of which is associated with the existence of neuroinflammatory response and oxidative stress. |
2024-04-17 |
2024-04-19 |
mouse |
| Chih-Hsin Lin, Yih-Ru Wu, Chih-Ying Chao, Kuo-Hsuan Chang, Chiung-Mei Chen, Wan-Ling Chen, Pei-Ning Yang, Guey-Jen Lee-Che. Protective Effects of Coptis chinensis Rhizome Extract and Its Constituents (Berberine, Coptisine, and Palmatine) against α-Synuclein Neurotoxicity in Dopaminergic SH-SY5Y Cells. Biological & pharmaceutical bulletin. vol 47. issue 4. 2024-04-10. PMID:38599826. |
parkinson's disease (pd) is a common neurodegenerative disease with progressive loss of dopaminergic neurons in substantia nigra and the presence of α-synuclein-immunoreactive inclusions. |
2024-04-10 |
2024-04-13 |
human |
| Seyed Zanyar Athari, Fereshteh Farajdokht, Rana Keyhanmanesh, Gisou Mohadde. AMPK Signaling Pathway as a Potential Therapeutic Target for Parkinson's Disease. Advanced pharmaceutical bulletin. vol 14. issue 1. 2024-04-08. PMID:38585465. |
parkinson's disease (pd) is the second most common neurodegenerative disease caused by the loss of dopaminergic neurons. |
2024-04-08 |
2024-04-10 |
Not clear |
| Rou Gu, Jianyu Pan, Maher Un Nisa Awan, Xiaowei Sun, Fang Yan, Liping Bai, Jie Ba. The major histocompatibility complex participates in Parkinson's disease. Pharmacological research. 2024-04-07. PMID:38583689. |
parkinson's disease (pd) is a common neurodegenerative disease characterized by progressive loss of dopaminergic neurons in the substantia nigra and the aggregation of alpha-synuclein (α-syn). |
2024-04-07 |
2024-04-10 |
Not clear |
| Hyeyoon Eo, Shin-Hye Yu, Yujin Choi, Yujin Kim, Young Cheol Kang, Hanbyeol Lee, Jin Hee Kim, Kyuboem Han, Hong Kyu Lee, Mi-Yoon Chang, Myung Sook Oh, Chun-Hyung Ki. Mitochondrial transplantation exhibits neuroprotective effects and improves behavioral deficits in an animal model of Parkinson's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. 2024-04-05. PMID:38580511. |
among the diseases related to mitochondrial dysfunction, parkinson's disease (pd) is the second most common neurodegenerative disease and is characterized by dopaminergic neuronal loss and neuroinflammation. |
2024-04-05 |
2024-04-10 |
mouse |
| Jean-Louis A Parmasad, Konrad M Ricke, Benjamin Nguyen, Morgan G Stykel, Brodie Buchner-Duby, Amanda Bruce, Haley M Geertsma, Eric Lian, Nathalie A Lengacher, Steve M Callaghan, Alvin Joselin, Julianna J Tomlinson, Michael G Schlossmacher, William L Stanford, Jiyan Ma, Patrik Brundin, Scott D Ryan, Maxime W C Rousseau. Genetic and pharmacological reduction of CDK14 mitigates synucleinopathy. Cell death & disease. vol 15. issue 4. 2024-04-04. PMID:38575601. |
parkinson's disease (pd) is a debilitating neurodegenerative disease characterized by the loss of midbrain dopaminergic neurons (dans) and the abnormal accumulation of α-synuclein (α-syn) protein. |
2024-04-04 |
2024-04-07 |
mouse |
| Jindong Zhao, Ji Wang, Kunying Zhao, Yuxiao Zhang, Weiyan H. Protopanaxadiols Eliminate Behavioral Impairments and Mitochondrial Dysfunction in Parkinson's Disease Mice Model. Neurochemical research. 2024-03-29. PMID:38551796. |
currently, there are no effective therapies to cure parkinson's disease (pd), which is the second most common neurodegenerative disease primarily characterized by motor dysfunction and degeneration of dopaminergic neurons in the substantia nigra pars compacta (snc). |
2024-03-29 |
2024-04-01 |
mouse |
| Bandar Alharbi, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Engy Elekhnawy, Hind Alharbi, Athanasios Alexiou, Marios Papadakis, Gaber El-Saber Batih. Role of GABA pathway in motor and non-motor symptoms in Parkinson's disease: a bidirectional circuit. European journal of medical research. vol 29. issue 1. 2024-03-28. PMID:38539252. |
parkinson's disease (pd) is a progressive neurodegenerative disease as a result of the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc). |
2024-03-28 |
2024-03-30 |
Not clear |
| Jianing Shen, Junhua Xie, Liyuan Ye, Jian Mao, Shihao Sun, Weiwei Chen, Sijia Wei, Sisi Ruan, Linhai Wang, Hangcui Hu, Jingjing Wei, Yao Zheng, Zhouyan Xi, Ke Wang, Yan X. Neuroprotective effect of green tea extract (-)-epigallocatechin-3-gallate in a preformed fibril-induced mouse model of Parkinson's disease. Neuroreport. 2024-03-25. PMID:38526966. |
parkinson's disease (pd) is the second most common neurodegenerative disease characterized by the progressive degeneration of dopaminergic neurons in the substantia nigra (sn). |
2024-03-25 |
2024-03-28 |
mouse |
| Haley M Geertsma, Zoe A Fisk, Lillian Sauline, Alice Prigent, Kevin Kurgat, Steve M Callaghan, Michael X Henderson, Maxime W C Rousseau. A topographical atlas of α-synuclein dosage and cell type-specific expression in adult mouse brain and peripheral organs. NPJ Parkinson's disease. vol 10. issue 1. 2024-03-20. PMID:38504090. |
parkinson's disease (pd) is the second most common neurodegenerative disease worldwide and presents pathologically with lewy pathology and dopaminergic neurodegeneration. |
2024-03-20 |
2024-03-23 |
mouse |
| Kanika Bhardwaj, Neelu Kanwar Rajawat, Nupur Mathu. Development of Alpha-Synuclein protein model against therapeutic aspects of Parkinson's disease. Indian journal of pharmacology. vol 56. issue 1. 2024-03-08. PMID:38454587. |
journal/ijpha/04.03/01363791-202456010-00007/figure1/v/2024-03-07t095025z/r/image-tiff parkinson's disease (pd) is the most common neurodegenerative disease caused by the steady depletion of dopamine in the striatum due to the loss of dopaminergic neurons. |
2024-03-08 |
2024-03-10 |
Not clear |
| Kandatege Wimalasena, Oluwatosin Adetuyi, Maya Eldan. Metabolic energy decline coupled dysregulation of catecholamine metabolism in physiologically highly active neurons: implications for selective neuronal death in Parkinson's disease. Frontiers in aging neuroscience. vol 16. 2024-03-07. PMID:38450382. |
parkinson's disease (pd) is an age-related irreversible neurodegenerative disease which is characterized as a progressively worsening involuntary movement disorder caused by the loss of dopaminergic (da) neurons in substantia nigra pars compacta (snpc). |
2024-03-07 |
2024-03-09 |
Not clear |
| Lingling Zhang, Hao Yan. Research progress of neural stem cells as a source of dopaminergic neurons for cell therapy in Parkinson's disease. Molecular biology reports. vol 51. issue 1. 2024-02-24. PMID:38400887. |
parkinson's disease (pd) is a neurodegenerative disease, the most characteristic pathological feature is the progressive loss of dopaminergic (da) neurons in the substantia nigra pars compactus (snpc) of the mesencephalon, along with reduced dopamine content in the striatum. |
2024-02-24 |
2024-02-27 |
Not clear |
| Areej Turkistani, Hayder M Al-Kuraishy, Ali I Al-Gareeb, Ali K Albuhadily, Athanasios Alexiou, Marios Papadakis, Mohamed M Elfiky, Hebatallah M Saad, Gaber El-Saber Batih. Therapeutic Potential Effect of Glycogen Synthase Kinase 3 Beta (GSK-3β) Inhibitors in Parkinson Disease: Exploring an Overlooked Avenue. Molecular neurobiology. 2024-02-17. PMID:38367137. |
parkinson's disease (pd) is a progressive neurodegenerative disease of the brain due to degeneration of dopaminergic neurons in the substantia nigra (sn). |
2024-02-17 |
2024-02-20 |
Not clear |
| Trittamon Phattanakiatsakul, Watcharapong Chaemsawang, Anan Athipornchai, Narongrit Thongon, Siriporn Chamniansawa. Biomedical reports. vol 20. issue 3. 2024-02-15. PMID:38357231. |
parkinson's disease (pd) is a common neurodegenerative disease induced by the death of dopaminergic neurons. |
2024-02-15 |
2024-02-17 |
Not clear |
| Jiannan Wang, Lijun Dai, Sichun Chen, Zhaohui Zhang, Xin Fang, Zhentao Zhan. Protein-protein interactions regulating α-synuclein pathology. Trends in neurosciences. 2024-02-14. PMID:38355325. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the degeneration of dopaminergic neurons in the substantia nigra pars compacta (snpc) and the formation of lewy bodies (lbs). |
2024-02-14 |
2024-02-17 |
Not clear |
| Juntao Cui, Di Zhao, Manman Xu, Zheheng Li, Junliang Qian, Ning Song, Jun Wang, Junxia Xi. Characterization of graded 6-Hydroxydopamine unilateral lesion in medial forebrain bundle of mice. Scientific reports. vol 14. issue 1. 2024-02-14. PMID:38355892. |
parkinson's disease (pd) is the second most common age-related neurodegenerative disease, with a progressive loss of dopaminergic cells and fibers. |
2024-02-14 |
2024-02-17 |
mouse |
| Mudiwa N Muwanigwa, Jennifer Modamio-Chamarro, Paul M A Antony, Gemma Gomez-Giro, Rejko Krüger, Silvia Bolognin, Jens C Schwambor. Alpha-synuclein pathology is associated with astrocyte senescence in a midbrain organoid model of familial Parkinson's disease. Molecular and cellular neurosciences. 2024-02-02. PMID:38307302. |
parkinson's disease (pd) is a complex, progressive neurodegenerative disease characterized by the loss of dopaminergic neurons in the substantia nigra pars compacta in the midbrain. |
2024-02-02 |
2024-02-05 |
human |
| Chong-Lei Fu, Bo-Cheng Dong, Xi Jiang, Dan Li, Jun Ya. A cell therapy approach based on iPSC-derived midbrain organoids for the restoration of motor function in a Parkinson's disease mouse model. Heliyon. vol 10. issue 2. 2024-01-31. PMID:38293351. |
parkinson's disease (pd) is a neurodegenerative disease characterized by the degeneration of dopaminergic (da) neurons in the substantia nigra and loss of da transmission in the striatum, thus making cell transplantation an effective treatment strategy. |
2024-01-31 |
2024-02-02 |
mouse |
| Bing Chen, Qian Zhang, Xiaoru Zhong, Xinwei Zhang, Xin Liu, Hongyang Wang, Fan Yang, Jingjing Zhang, Jingnan Huang, Yin-Kwan Wong, Piao Luo, Jigang Wang, Jichao Su. Dopamine modification of glycolytic enzymes impairs glycolysis: possible implications for Parkinson's disease. Cell communication and signaling : CCS. vol 22. issue 1. 2024-01-30. PMID:38287374. |
parkinson's disease (pd), a chronic and severe neurodegenerative disease, is pathologically characterized by the selective loss of nigrostriatal dopaminergic neurons. |
2024-01-30 |
2024-02-01 |
Not clear |