All Relations between gabaergic and muscarinic acetylcholine receptor

Publication Sentence Publish Date Extraction Date Species
Huanxin Chen, Ting He, Meiyi Li, Chunlian Wang, Chen Guo, Wei Wang, Baocong Yu, Jintao Huang, Lijun Cui, Ping Guo, Yonggui Yuan, Tao Ta. Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons. Frontiers in psychiatry. vol 13. 2023-01-30. PMID:36713928. therefore, characterizing the modulation effects of machr on gabaergic interneurons is crucial for understanding the mechanisms underlying scopolamine's antidepressant effects. 2023-01-30 2023-08-14 Not clear
Huanxin Chen, Ting He, Meiyi Li, Chunlian Wang, Chen Guo, Wei Wang, Baocong Yu, Jintao Huang, Lijun Cui, Ping Guo, Yonggui Yuan, Tao Ta. Cell-type-specific synaptic modulation of mAChR on SST and PV interneurons. Frontiers in psychiatry. vol 13. 2023-01-30. PMID:36713928. in this study, we examined the effect of machr activation on the excitatory synaptic transmissions in two major subtypes of gabaergic interneurons, somatostatin (sst)- and parvalbumin (pv)-expressing interneurons, in the anterior cingulate cortex (acc). 2023-01-30 2023-08-14 Not clear
Koyam Morales-Weil, Macarena Moreno, Juan Ahumada, Jorge Arriagada, Pablo Fuentealba, Christian Bonansco, Marco Fuenzalid. Priming of GABAergic Long-term Potentiation by Muscarinic Receptors. Neuroscience. vol 428. 2021-04-07. PMID:31917346. we have previously shown that co-activation of endocannabinoids (cb1r) and muscarinic receptor (machr) in hippocampal interneurons can induce activity-dependent gabaergic long-term depression in ca1 pyramidal neurons. 2021-04-07 2023-08-13 rat
Jun-Il Kang, Frédéric Huppé-Gourgues, Elvire Vauche. Pharmacological Mechanisms of Cortical Enhancement Induced by the Repetitive Pairing of Visual/Cholinergic Stimulation. PloS one. vol 10. issue 10. 2016-06-21. PMID:26513575. to better determine the receptor subtypes mediating this effect the selective pharmacological blockade of v1 nicotinic (nachr), m1 and m2 muscarinic (machr) or gabaergic a (gabaar) receptors was performed during the training session and visual evoked potentials (veps) were recorded before and after training. 2016-06-21 2023-08-13 rat
S Gigout, S Wierschke, T-N Lehmann, P Horn, C Dehnicke, R A Deis. Muscarinic acetylcholine receptor-mediated effects in slices from human epileptogenic cortex. Neuroscience. vol 223. 2013-05-01. PMID:22863677. xanomeline (m(1)/m(4) machr agonist) increased neuronal firing and decreased epsp, but had no effect on gabaergic transmission. 2013-05-01 2023-08-12 human
Petri Takkala, Melanie A Woodi. Muscarinic acetylcholine receptor activation prevents disinhibition-mediated LTP in the hippocampus. Frontiers in cellular neuroscience. vol 7. 2013-03-04. PMID:23450426. muscarinic acetylcholine receptor (machr) activation has previously been shown to regulate classic glutamatergic ltp, modulate intracellular [ca(2+)] and signaling, and facilitate the excitability of gabaergic interneurons in the ca1. 2013-03-04 2023-08-12 Not clear
Tao Liu, Tsugumi Fujita, Eiichi Kumamot. Acetylcholine and norepinephrine mediate GABAergic but not glycinergic transmission enhancement by melittin in adult rat substantia gelatinosa neurons. Journal of neurophysiology. vol 106. issue 1. 2011-11-08. PMID:21525362. nicotinic and muscarinic acetylcholine receptor agonists [(-)-nicotine and carbamoylcholine, respectively] and norepinephrine, as well as melittin, increased gabaergic sipsc frequency and amplitude. 2011-11-08 2023-08-12 rat
J C González, E Albiñana, P Baldelli, A G García, J M Hernández-Guij. Presynaptic muscarinic receptor subtypes involved in the enhancement of spontaneous GABAergic postsynaptic currents in hippocampal neurons. The European journal of neuroscience. vol 33. issue 1. 2011-04-14. PMID:21091801. we investigated the effects of muscarinic acetylcholine receptor (machr) activation on gabaergic synaptic transmission in rat hippocampal neurons. 2011-04-14 2023-08-12 rat
H-M Zhang, S-R Chen, Y-Q Cai, T E Richardson, L C Driver, G Lopez-Berestein, H-L Pa. Signaling mechanisms mediating muscarinic enhancement of GABAergic synaptic transmission in the spinal cord. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19110040. to study the signaling mechanisms involved in this unique machr action, gabaergic spontaneous inhibitory postsynaptic currents (sipscs) of lamina ii neurons were recorded using whole-cell patch clamp techniques in rat spinal cord slices. 2009-05-20 2023-08-12 rat
H-M Zhang, S-R Chen, Y-Q Cai, T E Richardson, L C Driver, G Lopez-Berestein, H-L Pa. Signaling mechanisms mediating muscarinic enhancement of GABAergic synaptic transmission in the spinal cord. Neuroscience. vol 158. issue 4. 2009-05-20. PMID:19110040. the machr agonist oxotremorine-m caused a profound increase in the frequency of gabaergic sipscs, which was abolished in the ca(2+)-free solution. 2009-05-20 2023-08-12 rat
Hong-Mei Zhang, Shao-Rui Chen, Minoru Matsui, Dinesh Gautam, Jürgen Wess, Hui-Lin Pa. Opposing functions of spinal M2, M3, and M4 receptor subtypes in regulation of GABAergic inputs to dorsal horn neurons revealed by muscarinic receptor knockout mice. Molecular pharmacology. vol 69. issue 3. 2006-04-19. PMID:16365281. the machr agonist oxotremorine-m (3-10 microm) dose-dependently decreased the frequency of gabaergic sipscs and mipscs in wild-type mice. 2006-04-19 2023-08-12 mouse
A Amadeo, P Arcelli, R Spreafico, S De Bias. Ultrastructural immunolocalization of muscarinic acetylcholine receptor in the dorsal thalamus of rat. Neuroscience letters. vol 184. issue 3. 1995-05-17. PMID:7715837. by combining the pre-embedding immunostaining for machr with post-embedding immunogold labeling for gaba it was shown that gabaergic terminals made synaptic contacts with cholinoceptive structures, but no machr ir was present at their post-synaptic sites. 1995-05-17 2023-08-12 rat
R Schliebs, M Zivin, J Steinbach, T Roth. Changes in cholinergic but not in GABAergic markers in amygdala, piriform cortex, and nucleus basalis of the rat brain following systemic administration of kainic acid. Journal of neurochemistry. vol 53. issue 1. 1989-07-13. PMID:2542459. three days after systemic administration of kainic acid (15 mg/kg, s.c.), selected cholinergic markers (choline acetyltransferase, acetylcholinesterase, muscarinic acetylcholine receptor, and high-affinity choline uptake) and gabaergic parameters [benzodiazepine and gamma-aminobutyric acid (gaba) receptors] were studied in the frontal and piriform cortex, dorsal hippocampus, amygdaloid complex, and nucleus basalis. 1989-07-13 2023-08-11 rat