| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Adam Wojtas, Agnieszka Bysiek, Agnieszka Wawrzczak-Bargiela, Marzena Maćkowiak, Krystyna Gołembiowsk. Limbic System Response to Psilocybin and Ketamine Administration in Rats: A Neurochemical and Behavioral Study. International journal of molecular sciences. vol 25. issue 1. 2024-01-11. PMID:38203271. |
the pathophysiology of depression is related to the reduced volume of the hippocampus and amygdala and hypertrophy of the nucleus accumbens. |
2024-01-11 |
2024-01-13 |
rat |
| Dylan N Peay, Amanda Acuna, Cindy M Reynolds, Chris Willis, Rujuta Takalkar, J Bryce Ortiz, Cheryl D Conra. Chronic stress leads to persistent and contrasting stellate neuron dendritic hypertrophy in the amygdala of male and female rats, an effect not found in the hippocampus. Neuroscience letters. 2023-07-20. PMID:37473795. |
chronic stress leads to persistent and contrasting stellate neuron dendritic hypertrophy in the amygdala of male and female rats, an effect not found in the hippocampus. |
2023-07-20 |
2023-08-14 |
rat |
| Shuai-Nan Zhang, Hong-Mei Li, Qi Liu, Xu-Zhao Li, Wu-de Yang, Ying Zho. Eucommiae Folium and Active Compounds Protect Against Mitochondrial Dysfunction-Calcium Overload in Epileptic Hippocampal Neurons Through the Hypertrophic Cardiomyopathy Pathway. Neurochemical research. 2023-04-17. PMID:37067737. |
eucommiae folium and active compounds protect against mitochondrial dysfunction-calcium overload in epileptic hippocampal neurons through the hypertrophic cardiomyopathy pathway. |
2023-04-17 |
2023-08-14 |
Not clear |
| Yue Liu, Hongwei Wen, Yun Pen. Cortical thinning and hippocampal hypertrophy: Two risk factors for adolescents and children with OSA. Sleep. 2023-01-08. PMID:36611279. |
cortical thinning and hippocampal hypertrophy: two risk factors for adolescents and children with osa. |
2023-01-08 |
2023-08-14 |
Not clear |
| Macarena S Aloi, Samantha J Thompson, Nicholas Quartapella, Jeffrey L Noebel. Loss of functional System x-c uncouples aberrant postnatal neurogenesis from epileptogenesis in the hippocampus of Kcna1-KO mice. Cell reports. vol 41. issue 8. 2022-11-23. PMID:36417872. |
mutations in kv1.1 (kcna1) voltage-gated potassium channels in humans and mice generate network hyperexcitability, enhancing aberrant postnatal neurogenesis in the dentate subgranular zone, resulting in epilepsy and hippocampal hypertrophy. |
2022-11-23 |
2023-08-14 |
mouse |
| Damira F Avgustinovich, Mikhail V Tenditnik, Natalia P Bondar, Mariya K Marenina, Svetlana Ya Zhanaeva, Maria N Lvova, Alexey V Katokhin, Konstantin S Pavlov, Veronica I Evseenko, Tatiana G Tolstikov. Behavioral effects and inflammatory markers in the brain and periphery after repeated social defeat stress burdened by Opisthorchis felineus infection in mice. Physiology & behavior. 2022-05-20. PMID:35594930. |
the combination caused liver hypertrophy and increased the blood level of proinflammatory cytokine interleukin 6 and proteolytic activity of cathepsin b in the hippocampus. |
2022-05-20 |
2023-08-13 |
mouse |
| Marcela Pereira, Isadora P Siba, Alexandra Acco, Diego Correia, Fernanda R Lapa, Adair Rs Santos, Ana P Ruani, Moacir G Pizzolatti, Roberto Andreatin. Myricitrin exhibits antidepressant-like effects and reduces IL-6 hippocampal levels in the chronic mild stress model. Behavioural brain research. 2022-05-01. PMID:35490774. |
myricitrin (10mg/kg, intraperitoneally, for 14 days) reversed depressive-like behaviors induced by cms (increased immobility in the fst, the tst and anhedonia), as well as decreased adrenal hypertrophy and hippocampal levels of il-6 in stressed mice. |
2022-05-01 |
2023-08-13 |
mouse |
| Frédérique K Kok, Suzanne L van Leerdam, Elizabeth C M de Lang. Potential Mechanisms Underlying Resistance to Dementia in Non-Demented Individuals with Alzheimer's Disease Neuropathology. Journal of Alzheimer's disease : JAD. 2022-03-11. PMID:35275527. |
furthermore, enhanced neural hypertrophy could compensate for hippocampal and cingulate neural atrophy in ndan individuals. |
2022-03-11 |
2023-08-13 |
human |
| Yu S Severyukhin, M Lalkovičová, D M Utina, K N Lyakhova, I A Kolesnikova, M E Ermolaeva, A G Molokanov, V N Gaevsky, D A Komarov, E A Krasavi. Comparative Analysis of Behavioral Reactions and Morphological Changes in the Rat Brain After Exposure to Ionizing Radiation with Different Physical Characteristics. Cellular and molecular neurobiology. 2022-01-04. PMID:34982311. |
morphological analysis showed the development of early amyloidosis, autolysis of the ependymal layer, an increase in the number of neurodegenerative changes in various structures of the brain, and the development of neuronal hypertrophy on the 30th day after irradiation in the cerebellum and hippocampal hilus. |
2022-01-04 |
2023-08-13 |
rat |
| Guangchi Sun, Zong Miao, Yangfan Ye, Pengzhan Zhao, Liang Fan, Zhongyuan Bao, Yiming Tu, Chong Li, Honglu Chao, Xiupeng Xu, Jing J. Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury. Brain research bulletin. vol 162. 2021-09-29. PMID:32502596. |
neuroinflammation was evaluated by astrocyte hypertrophy, activated microglia, and inflammatory factors in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Guangchi Sun, Zong Miao, Yangfan Ye, Pengzhan Zhao, Liang Fan, Zhongyuan Bao, Yiming Tu, Chong Li, Honglu Chao, Xiupeng Xu, Jing J. Curcumin alleviates neuroinflammation, enhances hippocampal neurogenesis, and improves spatial memory after traumatic brain injury. Brain research bulletin. vol 162. 2021-09-29. PMID:32502596. |
treatment with cur ameliorated the spatial memory of tbi rats, reduced tbi-induced chronic inflammation, typified by diminished astrocyte hypertrophy, reduction in activated microglia, declined inflammatory factors, and increased neurogenesis in the hippocampus. |
2021-09-29 |
2023-08-13 |
rat |
| Joshua D Bryant, Maheedhar Kodali, Bing Shuai, Saeed S Menissy, Paige J Graves, Thien Trong Phan, Robert Dantzer, Ashok K Shetty, Laura Ciaccia West, A Phillip Wes. Neuroimmune mechanisms of cognitive impairment in a mouse model of Gulf War illness. Brain, behavior, and immunity. vol 97. 2021-09-22. PMID:34333111. |
in addition, we report sex differences in response to gwic, with female mice showing more pronounced cognitive impairment and hippocampal astrocyte hypertrophy. |
2021-09-22 |
2023-08-13 |
mouse |
| Duk-Shin Lee, Ji-Eun Ki. Regional specific activations of ERK1/2 and CDK5 differently regulate astroglial responses to ER stress in the rat hippocampus following status epilepticus. Brain research. vol 1753. 2021-07-22. PMID:33422538. |
in the present study, tunicamycin-induced er stress resulted in reactive astrogliosis-like events showing astroglial hypertrophy with the elevated extracellular signal-activated protein kinase 1/2 (erk1/2) and cyclin-dependent kinase 5 (cdk5) phosphorylations in the ca1 region of the rat hippocampus. |
2021-07-22 |
2023-08-13 |
rat |
| Leelavathi N Madhu, Maheedhar Kodali, Sahithi Attaluri, Bing Shuai, Laila Melissari, Xiaolan Rao, Ashok K Shett. Melatonin improves brain function in a model of chronic Gulf War Illness with modulation of oxidative stress, NLRP3 inflammasomes, and BDNF-ERK-CREB pathway in the hippocampus. Redox biology. vol 43. 2021-07-05. PMID:33933884. |
behavioral tests revealed cognitive and mood dysfunction in gwi rats receiving vehicle, which were associated with elevated oxidative stress, reduced nrf2, catalase and mitochondrial complex proteins, astrocyte hypertrophy, activated microglia with nlrp3 inflammasomes, elevated proinflammatory cytokines, waned neurogenesis, and synapse loss in the hippocampus. |
2021-07-05 |
2023-08-13 |
rat |
| Andrea Du Preez, Diletta Onorato, Inez Eiben, Ksenia Musaelyan, Martin Egeland, Patricia A Zunszain, Cathy Fernandes, Sandrine Thuret, Carmine M Pariant. Chronic stress followed by social isolation promotes depressive-like behaviour, alters microglial and astrocyte biology and reduces hippocampal neurogenesis in male mice. Brain, behavior, and immunity. vol 91. 2021-05-27. PMID:32755644. |
however, ucmsi animals showed increased microglial activation in the ventral dentate gyrus (dg) of the hippocampus and astrocyte activation in both the dorsal and ventral dg, with increased gfap-positive cell immunoreactivity, gfap-positive cell hypertrophy and process extension, and increased s100β-positive cell density. |
2021-05-27 |
2023-08-13 |
mouse |
| Maria Elisa Morelli, Sara Baldini, Arianna Sartori, Laura D'Acunto, Alessandro Dinoto, Antonio Bosco, Alessio Bratina, Paolo Manganott. Early putamen hypertrophy and ongoing hippocampus atrophy predict cognitive performance in the first ten years of relapsing-remitting multiple sclerosis. Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology. vol 41. issue 10. 2021-05-14. PMID:32333180. |
early putamen hypertrophy and ongoing hippocampus atrophy predict cognitive performance in the first ten years of relapsing-remitting multiple sclerosis. |
2021-05-14 |
2023-08-13 |
Not clear |
| Heejung Chun, Heeyoung An, Jiwoon Lim, Junsung Woo, Jaekwang Lee, Hoon Ryu, C Justin Le. Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus. Experimental neurobiology. vol 27. issue 3. 2020-10-01. PMID:30022867. |
strikingly, a stab wound brain injury lead to hypertrophy of astrocytes accompanied by increased gaba expression and tonic gaba release in mouse ca1 hippocampus. |
2020-10-01 |
2023-08-13 |
mouse |
| Joana I Soares, Catarina Da Costa, Maria H Ferreira, Pedro A Andrade, Gisela H Maia, Nikolai V Lukoyano. Partial depletion of septohippocampal cholinergic cells reduces seizure susceptibility, but does not mitigate hippocampal neurodegeneration in the kainate model of epilepsy. Brain research. vol 1717. 2020-09-24. PMID:31028730. |
they do not support the hypothesis that epilepsy-related hypertrophy of cholinergic neurons may potentiate hippocampal cell loss and respective behavioral impairments. |
2020-09-24 |
2023-08-13 |
human |
| Shweta Prasad, Apurva Shah, Ketaki Swapnil Bhalsing, Keshav J Kumar, Jitender Saini, Madhura Ingalhalikar, Pramod Kumar Pa. Abnormal hippocampal subfields are associated with cognitive impairment in Essential Tremor. Journal of neural transmission (Vienna, Austria : 1996). vol 126. issue 5. 2020-07-01. PMID:30888510. |
significant atrophy of the left subiculum, ca4, granule-cell layer of dentate gyrus, right molecular layer, and hypertrophy of bilateral parasubiculum, right hippocampus-amygdala-transition-area, bilateral hippocampal tail (ht) and widening of right hippocampal fissure was observed in et. |
2020-07-01 |
2023-08-13 |
Not clear |
| Eduard Nicuşor Bondoc, Dragoş Marinescu, Ileana Marinescu, Ramona Denise Mălin, Liliana Stanca, Roxana Eugenia Zăvo. Current understanding of psycho-neurobiology in depressive disorders with suicidal thoughts - translational models. Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie. vol 60. issue 2. 2020-04-21. PMID:31658311. |
the vulnerability of hippocampal and frontal cortex cerebral structures is presented as obtained on animal model consecutive to hypothalamic-pituitary-adrenal (hpa) axis hyperactivity and on theoretical model where the hypothalamic disconnectivity determines the activation in the sympathetic autonomic nervous system, leading to heart disorders: high blood pressure, left ventricular hypertrophy and coronary illness. |
2020-04-21 |
2023-08-13 |
Not clear |