| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ana Paula Nadu, Anderson J Ferreira, Timothy L Reudelhuber, Michael Bader, Robson A S Santo. Reduced isoproterenol-induced renin-angiotensin changes and extracellular matrix deposition in hearts of TGR(A1-7)3292 rats. Journal of the American Society of Hypertension : JASH vol 2 issue 5 2013 20409916 |
we investigated the expression of specific extracellular matrix (ecm) proteins in cardiac hypertrophy induced by isoproterenol in tgr(a1-7)3292 rats. |
2013-07-04 |
2023-01-25 |
rat |
| Costas Tsioufis, Ioannis Bafakis, Alexandros Kasiakogias, Christodoulos Stefanadi. The role of matrix metalloproteinases in diabetes mellitus. Current topics in medicinal chemistry vol 12 issue 10 2013 22519446 |
in diabetic nephropathy, altered mmps expression contributes to extracellular matrix deposition and glomerular hypertrophy that eventually lead to proteinuria and renal insufficiency. |
2013-07-03 |
2023-01-25 |
Not clear |
| Qian Zhang, Kai Tao, Wei Huang, Yaguang Tian, Xiaoyan Li. Elevated expression of pleiotrophin in human hypertrophic scars. Journal of molecular histology vol 44 issue 1 2013 23054143 |
hypertrophic scar (hs) is a cutaneous fibrotic disorder characterized by persistent inflammation, excessive proliferation of fibroblasts, and abundant accumulation of extracellular matrix (ecm) proteins. |
2013-06-17 |
2023-01-25 |
human |
| Yi Cai, Shan-Shan Yu, Ting-Ting Chen, Si Gao, Biao Geng, Yang Yu, Jian-Tao Ye, Pei-Qing Li. EGCG inhibits CTGF expression via blocking NF-\\xce\\xbaB activation in cardiac fibroblast. Phytomedicine : international journal of phytotherapy and phytopharmacology vol 20 issue 2 2013 23141425 |
in heart, inappropriate increase in level of ctgf promotes fibroblast proliferation and extracellular matrix (ecm) accumulation, thereby exacerbating cardiac hypertrophy and subsequent failure. |
2013-06-10 |
2023-01-25 |
rat |
| F\\xc4\\xb1rat Seyfettino\\xc4\\x9flu, \\xc3\\x96zg\\xc3\\xbcr S\\xc3\\xbcnneli, Ali D\\xc3\\xbclgero\\xc4\\x9flu, Osman Arslan Bor. A case of ingrown toenail accompanied by extreme soft tissue hypertrophy to the extent of invisible nail. Acta orthopaedica et traumatologica turcica vol 46 issue 5 2013 23268828 |
we present hypertrophic tissue excision and bilateral partial matrix excision in an unclassified case of ingrown toenail in which the bilateral side wall hypertrophy covered the entire nail; normal tissue of the nail was invisible, along with first year follow-up results. |
2013-06-06 |
2023-01-25 |
Not clear |
| Elizabeth W Bradley, Lomeli R Carpio, Jennifer J Westendor. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of biological chemistry vol 288 issue 14 2013 23408427 |
these phenotypes led to the hypothesis that the akt/mtor pathway was repressed in these hdac3-deficient chondrocytes because akt promotes hypertrophy and matrix production in many tissues. |
2013-05-31 |
2023-01-25 |
mouse |
| Elizabeth W Bradley, Lomeli R Carpio, Jennifer J Westendor. Histone deacetylase 3 suppression increases PH domain and leucine-rich repeat phosphatase (Phlpp)1 expression in chondrocytes to suppress Akt signaling and matrix secretion. The Journal of biological chemistry vol 288 issue 14 2013 23408427 |
these data demonstrate that hdac3 controls chondrocyte hypertrophy and matrix content by repressing phlpp1 expression and facilitating akt activity. |
2013-05-31 |
2023-01-25 |
mouse |
| Kumar Kotlo, Keven R Johnson, Jean M Grillon, David L Geenen, Pieter deTombe, Robert S Danzige. Phosphoprotein abundance changes in hypertensive cardiac remodeling. Journal of proteomics vol 77 issue 2013 22659219 |
a total of 25 common phosphoproteins with differences in abundance in (1) the 3 hypertrophic and/or (2) the 2 systolic failure heart models were identified (ci>99%) by matrix assisted laser desorption ionization mass spectrometry (maldi-ms) and mascot analysis. |
2013-05-23 |
2023-01-25 |
rat |
| Qian Zhang, Xinhua Xiao, Ming Li, Wenhui Li, Miao Yu, Huabing Zhang, Xiaofang Sun, Lili Mao, Hongding Xian. Attenuating effect of Fufang Xueshuantong Capsule on kidney function in diabetic nephropathy model. Journal of natural medicines vol 67 issue 1 2013 22434410 |
kidney hypertrophy and glomerular mesangial matrix expansion were also ameliorated. |
2013-05-22 |
2023-01-25 |
rat |
| David Jj Saliken, Aillette Mulet-Sierra, Nadr M Jomha, Adetola B Adesid. Decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells. Arthritis research & therapy vol 14 issue 3 2013 22726892 |
decreased hypertrophic differentiation accompanies enhanced matrix formation in co-cultures of outer meniscus cells with bone marrow mesenchymal stromal cells. |
2013-05-22 |
2023-01-25 |
Not clear |
| Jan Menne, Nelli Shushakova, Janina Bartels, Yulia Kiyan, Robert Laudeley, Hermann Haller, Joon-Keun Park, Matthias Meie. Dual inhibition of classical protein kinase C-\\xce\\xb1 and protein kinase C-\\xce\\xb2 isoforms protects against experimental murine diabetic nephropathy. Diabetes vol 62 issue 4 2013 23434935 |
after 8 weeks of diabetes mellitus, the high-glucose-induced renal and glomerular hypertrophy as well as transforming growth factor-\xce\xb21) and extracellular matrix production were diminished in the pkc-\xce\xb1/\xce\xb2(-/-) mice compared with wild-type controls. |
2013-05-21 |
2023-01-25 |
mouse |
| Joanna Karbowska, Zdzis\\xc5\\x82aw Kocha. [Leptin as a mediator between obesity and cardiac dysfunction]. Postepy higieny i medycyny doswiadczalnej (Online) vol 66 issue 2013 22706112 |
moreover, leptin directly induced hypertrophy and hyperplasia in human and rodent cardiomyocytes, accompanied by cardiac extracellular matrix remodelling. |
2013-05-02 |
2023-01-25 |
human |
| Kavithalakshmi Sataranatarajan, Denis Feliers, Meenalakshmi M Mariappan, Hak Joo Lee, Myung Ja Lee, Robert T Day, Hima Bindu Yalamanchili, Goutam G Choudhury, Jeffrey L Barnes, Holly Van Remmen, Arlan Richardson, Balakuntalam S Kasinat. Molecular events in matrix protein metabolism in the aging kidney. Aging cell vol 11 issue 6 2013 23020145 |
renal hypertrophy was evident in middle-aged and old mice and was associated with glomerulomegaly and increase in mesangial fraction occupied by extracellular matrix. |
2013-04-18 |
2023-01-25 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials vol 34 issue 2 2013 23084553 |
increased crosslinking also promoted hypertrophic differentiation of the chondrogenically induced mscs, resulting in more matrix calcification in vitro. |
2013-04-15 |
2023-01-25 |
mouse |
| Liming Bian, Chieh Hou, Elena Tous, Reena Rai, Robert L Mauck, Jason A Burdic. The influence of hyaluronic acid hydrogel crosslinking density and macromolecular diffusivity on human MSC chondrogenesis and hypertrophy. Biomaterials vol 34 issue 2 2013 23084553 |
supplementation with inhibitors of the small gtpase pathway involved in cytoskeletal tension or myosin ii had no effect on hypertrophic differentiation and matrix calcification, indicating that the differential response is unlikely to be related to force-sensing mechanotransduction mechanisms. |
2013-04-15 |
2023-01-25 |
mouse |
| Dao-quan Tang, Ya-qin Wei, Xiao-xing Yin, Qian Lu, Hui-hui Hao, Yun-peng Zhai, Jian-yun Wang, Jin Re. In vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. Fitoterapia vol 82 issue 6 2013 21605637 |
in vitro suppression of quercetin on hypertrophy and extracellular matrix accumulation in rat glomerular mesangial cells cultured by high glucose. |
2013-04-08 |
2023-01-25 |
rat |
| In\\xc3\\xaas Falc\\xc3\\xa3o-Pires, Adelino F Leite-Moreir. Diabetic cardiomyopathy: understanding the molecular and cellular basis to progress in diagnosis and treatment. Heart failure reviews vol 17 issue 3 2013 21626163 |
left ventricular hypertrophy, metabolic abnormalities, extracellular matrix changes, small vessel disease, cardiac autonomic neuropathy, insulin resistance, oxidative stress, and apoptosis are the most important contributors to diabetic cardiomyopathy onset and progression. |
2013-04-05 |
2023-01-25 |
human |
| Erdogan Kocamaz, Duygu Gok, Ayse Cetinkaya, A Cevik Tufa. Implication of C-type natriuretic peptide-3 signaling in glycosaminoglycan synthesis and chondrocyte hypertrophy during TGF-\\xce\\xb21 induced chondrogenic differentiation of chicken bone marrow-derived mesenchymal stem cells. Journal of molecular histology vol 43 issue 5 2013 22714108 |
in conclusion, cnp-3/npr-b signaling may strongly be involved in synthesis of glycosaminoglycans of the chondrogenic matrix and hypertrophy of differentiated chondrocytes during tgf-\xce\xb21 induced chondrogenic differentiation of mscs. |
2013-04-03 |
2023-01-25 |
human |
| Elen Rizzi, Carla S Ceron, Danielle A Guimaraes, Cibele M Prado, Marcos A Rossi, Raquel F Gerlach, Jose E Tanus-Santo. Temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and TGF-\\xce\\xb2 in renovascular hypertension-induced cardiac hypertrophy. Experimental and molecular pathology vol 94 issue 1 2013 23073243 |
temporal changes in cardiac matrix metalloproteinase activity, oxidative stress, and tgf-\xce\xb2 in renovascular hypertension-induced cardiac hypertrophy. |
2013-04-03 |
2023-01-25 |
rat |
| Ivan Grskovic, Anna Kutsch, Christian Frie, Gergely Groma, Jacek Stermann, Ursula Schl\\xc3\\xb6tzer-Schrehardt, Anja Niehoff, Stephen E Moss, Sabrina Rosenbaum, Ernst P\\xc3\\xb6schl, Markus Chmielewski, Gunter Rappl, Hinrich Abken, John F Bateman, Kathryn Se Cheah, Mats Paulsson, Bent Brachvoge. Depletion of annexin A5, annexin A6, and collagen X causes no gross changes in matrix vesicle-mediated mineralization, but lack of collagen X affects hematopoiesis and the Th1/Th2 response. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 27 issue 11 2013 22692895 |
by binding to the extracellular matrix protein collagen x and matrix vesicles, annexins were proposed to anchor matrix vesicles in the extracellular space of hypertrophic chondrocytes to initiate the calcification of cartilage. |
2013-03-26 |
2023-01-25 |
mouse |