| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ling Wu, Stephanie Gonzalez, Saumya Shah, Levon Kyupelyan, Frank A Petrigliano, David R McAllister, John S Adams, Marcel Karperien, Tai-Lan Tuan, Paul D Benya, Denis Evseenk. Extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy. Tissue engineering. Part C, Methods. vol 20. issue 2. 2014-09-28. PMID:23758619. |
extracellular matrix domain formation as an indicator of chondrocyte dedifferentiation and hypertrophy. |
2014-09-28 |
2023-08-12 |
human |
| Qingwei Wen, Tao Liang, Feizhang Qin, Jinbin Wei, Qiaoling He, Xiu Luo, Xiaoyu Chen, Ni Zheng, Renbin Huan. Lyoniresinol 3α-O-β-D-glucopyranoside-mediated hypoglycaemia and its influence on apoptosis-regulatory protein expression in the injured kidneys of streptozotocin-induced mice. PloS one. vol 8. issue 12. 2014-09-27. PMID:24312585. |
diabetes-dependent alterations in the kidney such as glomerular hypertrophy, excessive extracellular matrix amassing, and glomerular and tubular basement membrane thickening were improved after 14 days of lgp1 treatment. |
2014-09-27 |
2023-08-12 |
mouse |
| Bardia Askari, Tomasz Wietecha, Kelly L Hudkins, Edward J Fox, Kevin D O'Brien, Jinkyu Kim, Tri Q Nguyen, Charles E Alper. Effects of CP-900691, a novel peroxisome proliferator-activated receptor α, agonist on diabetic nephropathy in the BTBR ob/ob mouse. Laboratory investigation; a journal of technical methods and pathology. vol 94. issue 8. 2014-09-26. PMID:24955894. |
despite these beneficial metabolic effects, cp had no effect on elevated plasma insulin, 8-epi pgf(2α) excretion, and albuminuria, and surprisingly, did not ameliorate the development of diabetic nephropathy, having no effect on the accumulation of renal macrophages, glomerular hypertrophy, and increased mesangial matrix expansion. |
2014-09-26 |
2023-08-13 |
mouse |
| Kang Lin, Lei Lü, Wei-Yang Gao, Zhi-Ling He, Guo-You Zhan. [Effects of agonists of PPAR-gamma on angiotensin II-induced proliferation and extracellular matrix synthesis in hypertrophic scar fibroblasts]. Zhonghua zheng xing wai ke za zhi = Zhonghua zhengxing waike zazhi = Chinese journal of plastic surgery. vol 29. issue 2. 2014-09-25. PMID:23772491. |
[effects of agonists of ppar-gamma on angiotensin ii-induced proliferation and extracellular matrix synthesis in hypertrophic scar fibroblasts]. |
2014-09-25 |
2023-08-12 |
Not clear |
| Anthony J Mirando, Yufeng Dong, Jinsil Kim, Matthew J Hilto. Isolation and culture of murine primary chondrocytes. Methods in molecular biology (Clifton, N.J.). vol 1130. 2014-09-25. PMID:24482180. |
to identify factors that are necessary and sufficient for chondrocyte hypertrophic differentiation and cartilage matrix mineralization, primary chondrocyte culture models have been developed. |
2014-09-25 |
2023-08-12 |
mouse |
| Lichen Yin, Xin Zhao, Shizhao Ji, Chunbai He, Guangyi Wang, Cui Tang, Shaohua Gu, Chunhua Yi. The use of gene activated matrix to mediate effective SMAD2 gene silencing against hypertrophic scar. Biomaterials. vol 35. issue 8. 2014-09-10. PMID:24388384. |
the use of gene activated matrix to mediate effective smad2 gene silencing against hypertrophic scar. |
2014-09-10 |
2023-08-12 |
Not clear |
| Lan Cheng, Jingli Chen, Xiaolu Ma. Everolimus vs. rapamycin for treating diabetic nephropathy in diabetic mouse model. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 31. issue 4. 2014-09-09. PMID:21823005. |
everolimus was significantly more effective than rapamycin in improving indexes of renal function and glomerular hypertrophy, and in decreasing accumulation and expansion of the extracellular matrix. |
2014-09-09 |
2023-08-12 |
mouse |
| J El-Hoss, M Kolind, M T Jackson, N Deo, K Mikulec, M M McDonald, C B Little, D G Little, A Schindele. Modulation of endochondral ossification by MEK inhibitors PD0325901 and AZD6244 (Selumetinib). Bone. vol 59. 2014-09-09. PMID:24269278. |
taken together, these data support the hypothesis that meki treatment can impact chondrocyte hypertrophy, matrix resorption, and fracture healing. |
2014-09-09 |
2023-08-12 |
mouse |
| Ineke C M Lavrijsen, Peter A J Leegwater, Alan J Martin, Stephen J Harris, Marianna A Tryfonidou, Henri C M Heuven, Herman A W Hazewinke. Genome wide analysis indicates genes for basement membrane and cartilage matrix proteins as candidates for hip dysplasia in Labrador Retrievers. PloS one. vol 9. issue 1. 2014-09-08. PMID:24498183. |
these genes are involved in hypertrophic differentiation of chondrocytes and extracellular matrix integrity of basement membrane and cartilage. |
2014-09-08 |
2023-08-12 |
Not clear |
| George Osol, Lorna G Moor. Maternal uterine vascular remodeling during pregnancy. Microcirculation (New York, N.Y. : 1994). vol 21. issue 1. 2014-09-04. PMID:23941526. |
this expansive, hypertrophic process results in increases in both lumen circumference and length, and is effected through a combination of tissue and cellular hypertrophy, endothelial and vascular smooth muscle hyperplasia, and matrix remodeling. |
2014-09-04 |
2023-08-12 |
human |
| Guofang Zeng, Fang Zhong, Jin Li, Shaojun Luo, Peihua Zhan. Resveratrol-mediated reduction of collagen by inhibiting proliferation and producing apoptosis in human hypertrophic scar fibroblasts. Bioscience, biotechnology, and biochemistry. vol 77. issue 12. 2014-08-18. PMID:24317052. |
hypertrophic scar (hs) is a dermal fibroproliferative disorder characterized by excessive deposition of extracellular matrix. |
2014-08-18 |
2023-08-12 |
human |
| F N Ziyadeh, M Isono, S Che. Involvement of the transforming growth factor-β system in the pathogenesis of diabetic nephropathy. Clinical and experimental nephrology. vol 6. issue 3. 2014-07-04. PMID:24989950. |
prominent among them is transforming growth factor-β (tgf-β), which promotes renal cell hypertrophy and stimulates extracellular matrix accumulation, the two hallmarks of diabetic renal disease. |
2014-07-04 |
2023-08-13 |
mouse |
| F N Ziyadeh, M Isono, S Che. Involvement of the transforming growth factor-β system in the pathogenesis of diabetic nephropathy. Clinical and experimental nephrology. vol 6. issue 3. 2014-07-04. PMID:24989950. |
in renal cell cultures, hypertrophy and matrix production are stimulated by high glucose concentrations in the culture media. |
2014-07-04 |
2023-08-13 |
mouse |
| F N Ziyadeh, M Isono, S Che. Involvement of the transforming growth factor-β system in the pathogenesis of diabetic nephropathy. Clinical and experimental nephrology. vol 6. issue 3. 2014-07-04. PMID:24989950. |
high glucose, in turn, appears to act through the tgf-β system; high glucose increases tgf-β expression, and the hypertrophic and matrix stimulatory effects of high glucose are prevented by anti-tgf-β therapy. |
2014-07-04 |
2023-08-13 |
mouse |
| F N Ziyadeh, M Isono, S Che. Involvement of the transforming growth factor-β system in the pathogenesis of diabetic nephropathy. Clinical and experimental nephrology. vol 6. issue 3. 2014-07-04. PMID:24989950. |
short-term treatment with the same neutralizing monoclonal antibodies against tgf-β in type 1 diabetic mice significantly reduces kidney weight and glomerular hypertrophy and attenuates the increase in extracellular matrix mrna. |
2014-07-04 |
2023-08-13 |
mouse |
| F N Ziyadeh, M Isono, S Che. Involvement of the transforming growth factor-β system in the pathogenesis of diabetic nephropathy. Clinical and experimental nephrology. vol 6. issue 3. 2014-07-04. PMID:24989950. |
the data we review here strongly support the hypothesis that elevated production or activity of the tgf-β system mediates diabetic renal hypertrophy and extracellular matrix expansion. |
2014-07-04 |
2023-08-13 |
mouse |
| Suji Kim, Jae Hyang Lim, Chang-Hoon Wo. ERK5 inhibition ameliorates pulmonary fibrosis via regulating Smad3 acetylation. The American journal of pathology. vol 183. issue 6. 2014-07-02. PMID:24095924. |
extracellular signal-regulated kinase (erk) 5, an atypical member of mitogen-activated protein kinase, promotes cardiac hypertrophy characterized with increased expression of fibrotic and extracellular matrix genes. |
2014-07-02 |
2023-08-12 |
Not clear |
| Jean-François Thibodeau, Rania Nasrallah, Anthony Carter, Ying He, Rhian Touyz, Richard L Hébert, Christopher R J Kenned. PTGER1 deletion attenuates renal injury in diabetic mouse models. The American journal of pathology. vol 183. issue 6. 2014-07-02. PMID:24113456. |
albuminuria, mesangial matrix expansion, and glomerular hypertrophy were each blunted in ep1(-/-) streptozotocin and ove26 cohorts compared with wild-type counterparts. |
2014-07-02 |
2023-08-12 |
mouse |
| Nirmal Parajuli, Vaibhav B Patel, Wang Wang, Ratnadeep Basu, Gavin Y Oudi. Loss of NOX2 (gp91phox) prevents oxidative stress and progression to advanced heart failure. Clinical science (London, England : 1979). vol 127. issue 5. 2014-06-30. PMID:24624929. |
increased cardiomyocyte hypertrophy and myocardial fibrosis in response to pressure overload correlated with increased oxidative stress, and loss of nox2 prevented the increase in oxidative stress, development of cardiomyocyte hypertrophy, myocardial fibrosis and increased myocardial mmp (matrix metalloproteinase) activity in response to pressure overload. |
2014-06-30 |
2023-08-12 |
mouse |
| Dina Abdallah, Eva Hamade, Raghida Abou Merhi, Badran Bassam, René Buchet, Saida Mebare. Fatty acid composition in matrix vesicles and in microvilli from femurs of chicken embryos revealed selective recruitment of fatty acids. Biochemical and biophysical research communications. vol 446. issue 4. 2014-06-24. PMID:24685481. |
hypertrophic chondrocytes participate in matrix mineralization by releasing matrix vesicles (mvs). |
2014-06-24 |
2023-08-12 |
chicken |