| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Sverre E Kjeldsen, Arne Strand, Stevo Julius, Peter M Oki. Mechanism of angiotensin II type 1 receptor blocker action in the regression of left ventricular hypertrophy. Journal of clinical hypertension (Greenwich, Conn.). vol 8. issue 7. 2006-12-19. PMID:16849902. |
in the development of left ventricular hypertrophy there is growth of cardiomyocytes and accumulation of extracellular matrix and fibrosis. |
2006-12-19 |
2023-08-12 |
Not clear |
| John F Bateman, Richard Wilson, Susanna Freddi, Shireen R Lamandé, Ravi Savariraya. Mutations of COL10A1 in Schmid metaphyseal chondrodysplasia. Human mutation. vol 25. issue 6. 2006-12-15. PMID:15880705. |
schmid metaphyseal chondrodysplasia (smcd) is a dominantly inherited cartilage disorder caused by mutations in the gene for the hypertrophic cartilage extracellular matrix structural protein, collagen x (col10a1). |
2006-12-15 |
2023-08-12 |
Not clear |
| Maria A Mello, Rocky S Tua. Effects of TGF-beta1 and triiodothyronine on cartilage maturation: in vitro analysis using long-term high-density micromass cultures of chick embryonic limb mesenchymal cells. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 24. issue 11. 2006-12-07. PMID:16955422. |
endochondral ossification is initiated by differentiation of mesenchymal cells into chondrocytes, which produce a cartilaginous matrix, proliferate, mature, and undergo hypertrophy, followed by matrix calcification, and substitution of cartilage by bone. |
2006-12-07 |
2023-08-12 |
chicken |
| Joachim Burkhard Grammer, Sabine Bleiziffer, Fabio Monticelli, Rüdiger Lange, Robert Bauernschmit. Calcineurin and matrix protein expression in cardiac hypertrophy: evidence for calcineurin B to control excessive hypertrophic signaling. Basic research in cardiology. vol 101. issue 4. 2006-12-05. PMID:16688406. |
calcineurin and matrix protein expression in cardiac hypertrophy: evidence for calcineurin b to control excessive hypertrophic signaling. |
2006-12-05 |
2023-08-12 |
human |
| Joachim Burkhard Grammer, Sabine Bleiziffer, Fabio Monticelli, Rüdiger Lange, Robert Bauernschmit. Calcineurin and matrix protein expression in cardiac hypertrophy: evidence for calcineurin B to control excessive hypertrophic signaling. Basic research in cardiology. vol 101. issue 4. 2006-12-05. PMID:16688406. |
in the compensatory state of human left ventricular hypertrophy (lvh), the remodeling processes in the extracellular matrix and the role of calcineurin (cn) are not completely understood. |
2006-12-05 |
2023-08-12 |
human |
| Ryszard Galus, Marek Antiszko, Paweł Włodarsk. [Clinical applications of hyaluronic acid]. Polski merkuriusz lekarski : organ Polskiego Towarzystwa Lekarskiego. vol 20. issue 119. 2006-12-05. PMID:16875173. |
ability of ha to create and fill space by organizing and modifying the extracellular matrix is widely used for soft tissue augmentation to limit age-related and photoinduced skin aging, but also may be used for correction of facial lipodystrophy and to prevent reccurence of hypertrophic scars or keloids. |
2006-12-05 |
2023-08-12 |
Not clear |
| Annemarie Brüel, Jens R Nyengaard, Carl Christian Danielse. MMP-2 in the left rat ventricle is increased by growth hormone. Growth hormone & IGF research : official journal of the Growth Hormone Research Society and the International IGF Research Society. vol 16. issue 3. 2006-12-04. PMID:16815061. |
these results indicate that mmp-2 may be involved in the remodelling process of the extracellular matrix in gh-induced cardiac hypertrophy. |
2006-12-04 |
2023-08-12 |
rat |
| I Friehs, R E Margossian, A M Moran, H Cao-Danh, M A Moses, P J del Nid. Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis. Basic research in cardiology. vol 101. issue 3. 2006-12-01. PMID:16369727. |
vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis. |
2006-12-01 |
2023-08-12 |
Not clear |
| I Friehs, R E Margossian, A M Moran, H Cao-Danh, M A Moses, P J del Nid. Vascular endothelial growth factor delays onset of failure in pressure-overload hypertrophy through matrix metalloproteinase activation and angiogenesis. Basic research in cardiology. vol 101. issue 3. 2006-12-01. PMID:16369727. |
since angiogenesis is associated with extracellular matrix degradation, we sought to determine whether vegf induced angiogenesis in hypertrophy required matrix metalloproteinases (mmp) activation. |
2006-12-01 |
2023-08-12 |
Not clear |
| Alexander V Ovechkin, Neetu Tyagi, Utpal Sen, David Lominadze, Mesia M Steed, Karni S Moshal, Suresh C Tyag. 3-Deazaadenosine mitigates arterial remodeling and hypertension in hyperhomocysteinemic mice. American journal of physiology. Lung cellular and molecular physiology. vol 291. issue 5. 2006-11-29. PMID:16815886. |
hhcy is associated with activation of matrix metalloproteinases (mmps); however, it is unclear whether hhcy-dependent extracellular matrix (ecm) accumulation plays a role in arterial hypertrophy and hypertension. |
2006-11-29 |
2023-08-12 |
mouse |
| David L Garbers, Ted D Chrisman, Phi Wiegn, Takeshi Katafuchi, Joseph P Albanesi, Vincent Bielinski, Barbara Barylko, Margaret M Redfield, John C Burnet. Membrane guanylyl cyclase receptors: an update. Trends in endocrinology and metabolism: TEM. vol 17. issue 6. 2006-11-13. PMID:16815030. |
recent studies have demonstrated key roles for several membrane guanylyl cyclase receptors in the regulation of cell hyperplasia, hypertrophy, migration and extracellular matrix production, all of which having an impact on clinically relevant diseases, including tissue remodeling after injury. |
2006-11-13 |
2023-08-12 |
Not clear |
| S W Jones, S M V Brockbank, M L Mobbs, N J Le Good, S Soma-Haddrick, A J Heuze, C J Langham, D Timms, P Newham, M R C Needha. The orphan G-protein coupled receptor RDC1: evidence for a role in chondrocyte hypertrophy and articular cartilage matrix turnover. Osteoarthritis and cartilage. vol 14. issue 6. 2006-11-09. PMID:16647866. |
the orphan g-protein coupled receptor rdc1: evidence for a role in chondrocyte hypertrophy and articular cartilage matrix turnover. |
2006-11-09 |
2023-08-12 |
human |
| Mangalalaxmy Subramanian, Ping-Ping Kuang, Lin Wei, David C Rishikof, Hanqiao Liu, Ronald H Goldstei. Modulation of amino acid uptake by TGF-beta in lung myofibroblasts. Journal of cellular biochemistry. vol 99. issue 1. 2006-11-06. PMID:16598748. |
transforming growth factor-beta (tgf-beta) stimulates amino acid uptake thereby inducing cell proliferation, cellular hypertrophy, and matrix synthesis. |
2006-11-06 |
2023-08-12 |
human |
| Maria Mirotsou, Victor J Dzau, Richard E Pratt, Ellen O Weinber. Physiological genomics of cardiac disease: quantitative relationships between gene expression and left ventricular hypertrophy. Physiological genomics. vol 27. issue 1. 2006-11-02. PMID:16835353. |
of genes with significant correlations to numerically continuous measurements of hypertrophy, we found enrichment for genes encoding extracellular matrix, growth-related and secreted proteins in the directly correlated subset, and for genes encoding mitochondria and metabolic/fatty acid oxidation proteins in the inversely correlated subset. |
2006-11-02 |
2023-08-12 |
mouse |
| Yung-Tsung Chiu, Ching-Chang Cheng, Nai-Nu Lin, Yi-Wen Hung, Ying-Tsung Chen, Shih-Lan Hsu, Ching-Shiang Chi, Yun-Ching F. High-dose norepinephrine induces disruption of myocardial extracellular matrix and left ventricular dilatation and dysfunction in a novel feline model. Journal of the Chinese Medical Association : JCMA. vol 69. issue 8. 2006-10-26. PMID:16970269. |
intravenous norepinephrine (ne) at a dose of 1-6 microg/kg/minute can induce increased extracellular matrix (ecm) and hypertrophic cardiomyopathy. |
2006-10-26 |
2023-08-12 |
Not clear |
| Sada Boodoo, Ernst W Spannhake, Jonathan D Powell, Maureen R Horto. Differential regulation of hyaluronan-induced IL-8 and IP-10 in airway epithelial cells. American journal of physiology. Lung cellular and molecular physiology. vol 291. issue 3. 2006-10-05. PMID:16581825. |
at the cellular level, the hallmarks of airway inflammation are mucus gland hypertrophy with excess mucus production, accumulation of inflammatory mediators, inflammation in the airway walls and lumen, and breakdown and turnover of the extracellular matrix. |
2006-10-05 |
2023-08-12 |
Not clear |
| Hiroyuki Tsutsu. Mitochondrial oxidative stress and heart failure. Internal medicine (Tokyo, Japan). vol 45. issue 13. 2006-09-15. PMID:16880705. |
reactive oxygen species induce myocyte hypertrophy, apoptosis, and interstitial fibrosis by activating matrix metalloproteinases. |
2006-09-15 |
2023-08-12 |
Not clear |
| Siham Madani, Sabrina De Girolamo, Diana Marcela Muñoz, Ren-Ke Li, Gary Sweene. Direct effects of leptin on size and extracellular matrix components of human pediatric ventricular myocytes. Cardiovascular research. vol 69. issue 3. 2006-08-18. PMID:16376323. |
both extracellular matrix remodeling and left ventricular hypertrophy are well-defined components of remodeling in heart failure, and here we further investigate the role of leptin, the obese gene product, on these parameters. |
2006-08-18 |
2023-08-12 |
human |
| Susanne Rutschow, Jun Li, Heinz-Peter Schultheiss, Matthias Pauschinge. Myocardial proteases and matrix remodeling in inflammatory heart disease. Cardiovascular research. vol 69. issue 3. 2006-08-18. PMID:16417902. |
the myocardial inflammatory reaction not only affects myocardial hypertrophy and apoptosis, but it has a major influence on the regulation of extracellular matrix turnover. |
2006-08-18 |
2023-08-12 |
Not clear |
| Ernestina Schipan. Hypoxia and HIF-1alpha in chondrogenesis. Annals of the New York Academy of Sciences. vol 1068. 2006-08-08. PMID:16831906. |
in endochondral bone development chondrocytes undergo proliferation, hypertrophic differentiation, mineralization of the surrounding matrix, death, blood vessel invasion, and finally replacement of cartilage with bone. |
2006-08-08 |
2023-08-12 |
Not clear |