| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Tsutsumi, H Matsubara, N Ohkubo, Y Mori, Y Nozawa, S Murasawa, K Kijima, K Maruyama, H Masaki, Y Moriguchi, Y Shibasaki, H Kamihata, M Inada, T Iwasak. Angiotensin II type 2 receptor is upregulated in human heart with interstitial fibrosis, and cardiac fibroblasts are the major cell type for its expression. Circulation research vol 83 issue 10 1998 9815151 |
cardiac hypertrophy suggested by atrial and brain natriuretic peptide levels was comparably increased in omi and dcm, whereas accumulation of matrix proteins such as collagen type 1 and fibronectin was much more prominent in dcm than in omi. |
1998-12-03 |
2023-01-24 |
human |
| U I Chung, B Lanske, K Lee, E Li, H Kronenber. The parathyroid hormone/parathyroid hormone-related peptide receptor coordinates endochondral bone development by directly controlling chondrocyte differentiation. Proceedings of the National Academy of Sciences of the United States of America vol 95 issue 22 1998 9789035 |
moreover, abnormal chondrocyte differentiation affects mineralization of cartilaginous matrix in a non-cell autonomous fashion; matrix mineralization requires a critical mass of adjacent ectopic hypertrophic chondrocytes. |
1998-11-24 |
2023-01-24 |
mouse |
| M A Ross. Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. Journal of hypertension vol 16 issue 7 1998 9794745 |
pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. |
1998-11-20 |
2023-01-24 |
Not clear |
| M A Ross. Pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. Journal of hypertension vol 16 issue 7 1998 9794745 |
to investigate pathologic fibrosis and connective tissue matrix in left ventricular hypertrophy due to chronic arterial hypertension in humans. |
1998-11-20 |
2023-01-24 |
Not clear |
| E A Jaimes, J M Galceran, L Rai. Angiotensin II induces superoxide anion production by mesangial cells. Kidney international vol 54 issue 3 1998 9734602 |
indeed, growth stimulating signals driven by ang ii promote mesangial cell (mc) hypertrophy and extracellular matrix production, prominent features of progressive glomerular injury. |
1998-11-17 |
2023-01-24 |
Not clear |
| P A Tooney, T Sakai, K Sakai, D Aeschlimann, D F Moshe. Restricted localization of thrombospondin-2 protein during mouse embryogenesis: a comparison to thrombospondin-1. Matrix biology : journal of the International Society for Matrix Biology vol 17 issue 2 1998 9694593 |
tsp1 was found in cartilage proper with diminished staining around chondrocytes undergoing differentiation and hypertrophy, whereas tsp2 was restricted to the matrix surrounding chondrocytes of the growth zone cartilage. |
1998-11-03 |
2023-01-24 |
mouse |
| P Bianco, F D Cancedda, M Riminucci, R Cancedd. Bone formation via cartilage models: the \"borderline\" chondrocyte. Matrix biology : journal of the International Society for Matrix Biology vol 17 issue 3 1998 9707341 |
in vitro, when replated as adherent cells in the presence of ascorbic acid, hypertrophic chondrocytes resume cell proliferation, switch from the synthesis of the cartilage-characteristic type ii and x collagens to the synthesis of type i collagen, and organize a mineralizing bone matrix. |
1998-11-03 |
2023-01-24 |
Not clear |
| P Bianco, F D Cancedda, M Riminucci, R Cancedd. Bone formation via cartilage models: the \"borderline\" chondrocyte. Matrix biology : journal of the International Society for Matrix Biology vol 17 issue 3 1998 9707341 |
in bones formed via cartilage models, the first mineralized bone matrix (the earliest bony collar preceding vascular invasion and the onset of endochondral bone formation) is deposited at the outer aspect of the mid-diaphysis between rows of early hypertrophic chondrocytes and osteoblasts, which are arranged in a peculiar "vis \xc3\xa0 vis" fashion. |
1998-11-03 |
2023-01-24 |
Not clear |
| P Bianco, F D Cancedda, M Riminucci, R Cancedd. Bone formation via cartilage models: the \"borderline\" chondrocyte. Matrix biology : journal of the International Society for Matrix Biology vol 17 issue 3 1998 9707341 |
hypertrophic chondrocytes located in different cartilage areas are exposed to an inappropriate matrix and endocrine/paracrine environment, cannot differentiate to osteoblast-like cells and therefore undergo apoptosis. |
1998-11-03 |
2023-01-24 |
Not clear |
| D Chan, O Jacenk. Phenotypic and biochemical consequences of collagen X mutations in mice and humans. Matrix biology : journal of the International Society for Matrix Biology vol 17 issue 3 1998 9707340 |
this review focuses on how these two approaches are being used to address the role of collagen x, the major extracellular matrix component of the focal zone of endochondral ossification, the hypertrophic cartilage zone. |
1998-11-03 |
2023-01-24 |
mouse |
| R A Terkeltaub, K Johnson, D Rohnow, R Goomer, D Burton, L J Defto. Bone morphogenetic proteins and bFGF exert opposing regulatory effects on PTHrP expression and inorganic pyrophosphate elaboration in immortalized murine endochondral hypertrophic chondrocytes (MCT cells). Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 13 issue 6 1998 9626624 |
opposing effects of bfgf and bmps also were exerted on the elaboration of inorganic pyrophosphatase (ppi), which regulates the ability of hypertrophic chondrocytes to mineralize the matrix. |
1998-10-22 |
2023-01-24 |
Not clear |
| H I Roach, J E Baker, N M Clark. Initiation of the bony epiphysis in long bones: chronology of interactions between the vascular system and the chondrocytes. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 13 issue 6 1998 9626626 |
where at least two vessels were in apposition, a new pseudo-ossification center was initiated: chondrocytes became hypertrophic and the matrix calcified. |
1998-10-22 |
2023-01-24 |
Not clear |
| S Otsuka, M Sugano, N Makino, S Sawada, T Hata, Y Nih. Interaction of mRNAs for angiotensin II type 1 and type 2 receptors to vascular remodeling in spontaneously hypertensive rats. Hypertension (Dallas, Tex. : 1979) vol 32 issue 3 1998 9740612 |
these results indicate that at1 receptor, but not at2 receptor, plays a crucial role in the remodeling of matrix tissue, while at2 receptor may play a role in the development of hypertrophy of smooth muscle in aorta in shr, and that the reduction of hypertrophy of smooth muscle does not fully account for the suppression of hypertension. |
1998-10-15 |
2023-01-24 |
rat |
| M Sato, O Ishikawa, Y Miyach. Distinct patterns of collagen gene expression are seen in normal and keloid fibroblasts grown in three-dimensional culture. The British journal of dermatology vol 138 issue 6 1998 9747353 |
fibroblasts from keloids and hypertrophic scar may have a defective system of down-regulation in extracellular matrix metabolism. |
1998-10-08 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
to define the contributions of changes in cell, matrix compartment, and fibrillar collagen volumes to longitudinal bone growth, we measured the differences in cell, pericellular/territorial matrix and interterritorial matrix volumes, and fibrillar collagen concentrations between the upper proliferative and lower hypertrophic zones of the proximal tibial physes of six miniature pigs. |
1998-10-06 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
the mean cell volume increased nearly 5-fold (from 1,174 to 5,530 microm3), and the total matrix volume per cell increased 46% (from 8,040 to 11,760 microm3/cell) between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
both the pericellular/territorial matrix volume per cell and the interterritorial matrix volume per cell increased between the upper proliferative and lower hypertrophic zones; the pericellular/territorial matrix volume per cell increased 61% (from 4,580 to 7,390 microm3/cell), whereas the interterritorial matrix volume per cell increased 26% (from 3,460 to 4,370 microm3/cell). |
1998-10-06 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
fibrillar collagen concentration was greater in the interterritorial matrix than in the pericellular/territorial matrix in both zones and increased in both matrix compartments between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
the amount of fibrillar collagen per cell also increased in both matrix compartments between the upper proliferative and lower hypertrophic zones (from 1,720 to 3,100 microm3/cell in the pericellular/territorial matrix and from 1,490 to 2,230 microm3/cell in the interterritorial matrix; thus, the total amount of fibrillar collagen per cell increased from 3,210 to 5,530 microm3/cell). |
1998-10-06 |
2023-01-24 |
Not clear |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
growth rate was inversely related to the cell numerical density in the upper proliferative and lower hypertrophic zones and was directly related to interterritorial matrix volume per cell in the upper proliferative zone and to pericellular/territorial matrix volume per cell in the lower hypertrophic zone. |
1998-10-06 |
2023-01-24 |
Not clear |