| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| K J Noonan, E B Hunziker, J Nessler, J A Buckwalte. Changes in cell, matrix compartment, and fibrillar collagen volumes between growth-plate zones. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 16 issue 4 1998 9747793 |
these results show that cell enlargement contributes more to longitudinal bone growth than does increased matrix volume, that increased pericellular/territorial matrix volume makes a greater contribution to growth than does increased interterritorial matrix volume, and that the total amount of fibrillar collagen per cell increases between the upper proliferative and lower hypertrophic zones. |
1998-10-06 |
2023-01-24 |
Not clear |
| C Farquharson, J L Berry, E B Mawer, E Seawright, C C Whitehea. Ascorbic acid-induced chondrocyte terminal differentiation: the role of the extracellular matrix and 1,25-dihydroxyvitamin D. European journal of cell biology vol 76 issue 2 1998 9696350 |
ascorbic acid-induced chondrocyte terminal differentiation: the role of the extracellular matrix and 1,25-dihydroxyvitamin d. chondrocyte terminal differentiation is associated with cellular hypertrophy increased activity of plasma membrane alkaline phosphatase and the synthesis of collagen type x. |
1998-10-05 |
2023-01-24 |
Not clear |
| S M Ali, N J Laping, T A Fredrickson, L C Contino, B a Olson, K Anderson, D P Brook. Angiotensin-converting enzyme inhibition attenuates proteinuria and renal TGF-beta 1 mRNA expression in rats with chronic renal disease. Pharmacology vol 57 issue 1 1998 9670209 |
evidence suggests that transforming growth factor beta 1 (tgf-beta 1), a multifunctional cytokine, induces renal extracellular matrix production and glomerular hypertrophy. |
1998-10-01 |
2023-01-24 |
rat |
| M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology vol 142 issue 4 1998 9722623 |
the enzymatic analyses also show that appreciable transglutaminase activity in the hypertrophic zone becomes externalized into the extracellular matrix. |
1998-09-25 |
2023-01-24 |
human |
| M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology vol 142 issue 4 1998 9722623 |
this produces autocatalytic cell death, externalization of the enzyme, and presumably cross-linking of components within the hypertrophic matrix. |
1998-09-25 |
2023-01-24 |
human |
| M Nurminskaya, C Magee, D Nurminsky, T F Linsenmaye. Plasma transglutaminase in hypertrophic chondrocytes: expression and cell-specific intracellular activation produce cell death and externalization. The Journal of cell biology vol 142 issue 4 1998 9722623 |
these changes may in turn regulate the removal and/or calcification of this hypertrophic matrix, which are its ultimate fates. |
1998-09-25 |
2023-01-24 |
human |
| S Lehoux, A Tedgu. Signal transduction of mechanical stresses in the vascular wall. Hypertension (Dallas, Tex. : 1979) vol 32 issue 2 1998 9719064 |
the processes involved in vascular remodeling include cellular hypertrophy and hyperplasia, as well as enhanced protein synthesis or extracellular matrix protein reorganization. |
1998-09-09 |
2023-01-24 |
Not clear |
| Y Sasano, I Takahashi, I Mizoguchi, M Kagayama, H Takita, Y Kubok. Type X collagen is not localized in hypertrophic or calcified cartilage in the developing rat trachea. Anatomy and embryology vol 197 issue 5 1998 9623674 |
our previous studies have shown that rat tracheal chondrocytes become larger and hypertrophic, and that the cartilage matrix calcifies during development. |
1998-08-07 |
2023-01-24 |
rat |
| R L Broverman, K H Nguyen, A da Silveira, L L Brinkley, S P Macauley, T Zeng, H Yamamoto, R W Tarnuzzer, G S Schultz, M Kerr, M G Humphreys-Behe. Changes in the expression of extracellular matrix (ECM) and matrix metalloproteinases (MMP) of proliferating rat parotid acinar cells. Journal of dental research vol 77 issue 7 1998 9663435 |
daily administration of the broad-spectrum matrix metalloproteinase inhibitor galardin for 3 days in combination with isoproterenol resulted in enhanced gland hypertrophy compared with that produced by isoproterenol alone. |
1998-07-30 |
2023-01-24 |
rat |
| D Nie, Y Ishikawa, Y Guo, L N Wu, B R Genge, R E Wuthier, G R Saue. Inhibition of terminal differentiation and matrix calcification in cultured avian growth plate chondrocytes by Rous sarcoma virus transformation. Journal of cellular biochemistry vol 69 issue 4 1998 9620171 |
endochondral bone formation involves the progression of epiphyseal growth plate chondrocytes through a sequence of developmental stages which include proliferation, differentiation, hypertrophy, and matrix calcification. |
1998-07-23 |
2023-01-24 |
Not clear |
| R S Ross, C Pham, S Y Shai, J I Goldhaber, C Fenczik, C C Glembotski, M H Ginsberg, J C Loftu. Beta1 integrins participate in the hypertrophic response of rat ventricular myocytes. Circulation research vol 82 issue 11 1998 9633916 |
the hypertrophic response of this model required interaction with extracellular matrix proteins. |
1998-07-02 |
2023-01-24 |
rat |
| S R Gudi, A A Lee, C B Clark, J A Frango. Equibiaxial strain and strain rate stimulate early activation of G proteins in cardiac fibroblasts. The American journal of physiology vol 274 issue 5 1998 9612231 |
cardiac fibroblasts are responsible for the production of the extracellular matrix of the heart, with alterations of fibroblast function implicated in myocardial infarction and cardiac hypertrophy. |
1998-07-01 |
2023-01-24 |
rat |
| E E Mancilla, F De Luca, J A Uyeda, F S Czerwiec, J Baro. Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology vol 139 issue 6 1998 9607800 |
we next assessed each major component of longitudinal growth: proliferation, cellular hypertrophy, and cartilage matrix synthesis. |
1998-06-24 |
2023-01-24 |
rat |
| E E Mancilla, F De Luca, J A Uyeda, F S Czerwiec, J Baro. Effects of fibroblast growth factor-2 on longitudinal bone growth. Endocrinology vol 139 issue 6 1998 9607800 |
we conclude that fgf-2 inhibits longitudinal bone growth by three mechanisms: decreased growth plate chondrocyte proliferation, decreased cellular hypertrophy, and, at high concentrations, decreased cartilage matrix production. |
1998-06-24 |
2023-01-24 |
rat |
| M Yoshiyama, K Takeuchi, S Kim, A Hanatani, T Omura, I Toda, K Akioka, M Teragaki, H Iwao, J Yoshikaw. Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. Japanese circulation journal vol 62 issue 1 1998 9559417 |
we examined the effect of a calcium antagonist, manidipine hydrochloride, on cardiac hypertrophy and the expression of the atrial natriuretic peptide (anp), transforming growth factor beta 1 (tgf-beta 1), and extracellular matrix protein genes in rats with isoproterenol-induced cardiac hypertrophy. |
1998-06-16 |
2023-01-24 |
rat |
| M Yoshiyama, K Takeuchi, S Kim, A Hanatani, T Omura, I Toda, K Akioka, M Teragaki, H Iwao, J Yoshikaw. Effect of manidipine hydrochloride, a calcium antagonist, on isoproterenol-induced left ventricular hypertrophy. Japanese circulation journal vol 62 issue 1 1998 9559417 |
thus, manidipine hydrochloride prevented cardiac hypertrophy and changes in the expression of genes for anp and interstitial components of extracellular matrix induced by isoproterenol. |
1998-06-16 |
2023-01-24 |
rat |
| T F Linsenmayer, F Long, M Nurminskaya, Q Chen, T M Schmi. Type X collagen and other up-regulated components of the avian hypertrophic cartilage program. Progress in nucleic acid research and molecular biology vol 60 issue 1998 9594572 |
we provide evidence that the molecule has unique diffusion and regulatory properties that combine to alter the hypertrophic cartilage matrix. |
1998-06-15 |
2023-01-24 |
Not clear |
| B O Oyajobi, A Frazer, A P Hollander, R M Graveley, C Xu, A Houghton, P V Hatton, R G Russell, B M Stringe. Expression of type X collagen and matrix calcification in three-dimensional cultures of immortalized temperature-sensitive chondrocytes derived from adult human articular cartilage. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 13 issue 3 1998 9525344 |
in addition, in the presence of ascorbate but in the absence of a phosphate donor or inorganic phosphate supplement, the cells also begin to express a hypertrophic phenotype characterized by type x collagen synthesis and extensive mineralization of the extracellular matrix in late stage cultures. |
1998-06-10 |
2023-01-24 |
human |
| K Ohshiro, P Pur. Pathogenesis of infantile hypertrophic pyloric stenosis: recent progress. Pediatric surgery international vol 13 issue 4 1998 9553181 |
reviews of the recent progress in the pathogenesis of ihps show: (1) there is increasing evidence to suggest that smooth-muscle cells in ihps are not properly innervated; (2) because non-adrenergic, non-cholinergic nerves are mediators of smooth-muscle relaxation, it is likely that the absence of these nerves in pyloric muscle is the cause of excessively contracted hypertrophic circular pyloric muscle; (3) there are abnormal amounts of extracellular matrix proteins in hypertrophic pyloric muscle. |
1998-06-10 |
2023-01-24 |
Not clear |
| P Vanky, U Brockstedt, A Hjerpe, B Wikstr\\xc3\\xb6. Kinetic studies on epiphyseal growth cartilage in the normal mouse. Bone vol 22 issue 4 1998 9556132 |
the largest increases in matrix volume occurred in the hypertrophic zone. |
1998-06-03 |
2023-01-24 |
mouse |