| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Heidland, H Ling, S Vamvakas, L Pacze. Impaired proteolytic activity as a potential cause of progressive renal disease. Mineral and electrolyte metabolism vol 22 issue 1-3 1996 8676810 |
renal hypertrophy (an increase in cellular protein content and cellularity as well as an accumulation of extracellular matrix) is due to the imbalance between protein synthesis and degradation. |
1996-08-12 |
2023-01-24 |
Not clear |
| L Schaefer, K Meier, C H\\xc3\\xa4fner, M Teschner, A Heidland, R M Schaefe. Protein restriction influences glomerular matrix turnover and tubular hypertrophy by modulation of renal proteinase activities. Mineral and electrolyte metabolism vol 22 issue 1-3 1996 8676812 |
protein restriction influences glomerular matrix turnover and tubular hypertrophy by modulation of renal proteinase activities. |
1996-08-12 |
2023-01-24 |
rat |
| A Cobo, E Carbajo, F Santos, E Garc\\xc3\\xada, J M L\\xc3\\xb3pe. Morphometry of uremic rat growth plate. Mineral and electrolyte metabolism vol 22 issue 1-3 1996 8676817 |
this is consistent with an abnormal metabolism of condrocytes as shown by a lower mean area of extracellular matrix (ema) per cell in the hypertrophic zone of the nx rats (0.23 vs. 0.58 microns 2). |
1996-08-12 |
2023-01-24 |
rat |
| M Alini, A Marriott, T Chen, S Abe, A R Pool. A novel angiogenic molecule produced at the time of chondrocyte hypertrophy during endochondral bone formation. Developmental biology vol 176 issue 1 1996 8654888 |
when cultured these cells produce an extensive extracellular matrix and the prehypertrophic cells mature to express the hypertrophic phenotype defined by the synthesis of type x collagen and matrix calcification. |
1996-07-31 |
2023-01-24 |
cattle |
| A Ghahary, Y J Shen, B Nedelec, R Wang, P G Scott, E E Tredge. Collagenase production is lower in post-burn hypertrophic scar fibroblasts than in normal fibroblasts and is reduced by insulin-like growth factor-1. The Journal of investigative dermatology vol 106 issue 3 1996 8648180 |
we recently demonstrated that the accumulation of extracellular matrix in post-burn hypertrophic scarring (hsc) tissues is, in part, caused by an overexpression of mrna for fibronectin, type i, and type iii procollagen. |
1996-07-25 |
2023-01-24 |
Not clear |
| T Ogawa, W Linz, M Stevenson, B G Bruneau, M L Kuroski de Bold, J H Chen, H Eid, B A Sch\\xc3\\xb6lkens, A J de Bol. Evidence for load-dependent and load-independent determinants of cardiac natriuretic peptide production. Circulation vol 93 issue 11 1996 8640983 |
myosin heavy chain (mhc) isoform switch was studied as an indicator of ventricular cardiocyte hypertrophy as well as the levels of collagen iii mrna as a measure of changes in extracellular matrix. |
1996-07-17 |
2023-01-24 |
rat |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes vol 45 issue 4 1996 8603776 |
neutralization of tgf-beta by anti-tgf-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in stz-induced diabetic mice. |
1996-05-13 |
2023-01-24 |
mouse |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes vol 45 issue 4 1996 8603776 |
diabetic nephropathy is characterized by renal hypertrophy, thickening of basement membranes, and accumulation of extracellular matrix in the glomerular mesangium and the interstitium. |
1996-05-13 |
2023-01-24 |
mouse |
| K Sharma, Y Jin, J Guo, F N Ziyade. Neutralization of TGF-beta by anti-TGF-beta antibody attenuates kidney hypertrophy and the enhanced extracellular matrix gene expression in STZ-induced diabetic mice. Diabetes vol 45 issue 4 1996 8603776 |
this is the first demonstration that the early characteristic features of diabetic renal involvement, which include hypertrophy and increased matrix mrnas, are largely mediated by increased endogenous tgf-beta activity in the kidney and that they can be significantly attenuated by treatment with neutralizing anti-tgf-beta antibodies. |
1996-05-13 |
2023-01-24 |
mouse |
| K Thompson, M Rabinovitc. Exogenous leukocyte and endogenous elastases can mediate mitogenic activity in pulmonary artery smooth muscle cells by release of extracellular-matrix bound basic fibroblast growth factor. Journal of cellular physiology vol 166 issue 3 1996 8600153 |
there is increasing evidence that extracellular matrix (ecm)-degrading proteinases contribute to the process of medial hypertrophy and neointimal proliferation in pulmonary vascular diseases. |
1996-05-02 |
2023-01-24 |
human |
| H K Gahunia, P Babyn, C Lemaire, M J Kessler, K P Pritzke. Osteoarthritis staging: comparison between magnetic resonance imaging, gross pathology and histopathology in the rhesus macaque. Osteoarthritis and cartilage vol 3 issue 3 1996 8581746 |
however, at this time, while mri is sensitive for detecting oa change it cannot distinguish between certain lesions such as superficial cartilage matrix fibrillation and hypertrophy both of which show elevated signal intensity. |
1996-03-21 |
2023-01-24 |
monkey |
| B R Olse. Mutations in collagen genes resulting in metaphyseal and epiphyseal dysplasias. Bone vol 17 issue 2 Suppl 1996 8579897 |
combined mouse and human studies demonstrate that a unique extracellular matrix molecule (collagen x) in the mineralizing hypertrophic zone of growth plates is essential for normal growth plate function. |
1996-03-20 |
2023-01-24 |
mouse |
| S J van't Veen, J W Hagen, F C van Ginkel, B Prahl-Andersen, E H Burge. Intermittent compression stimulates cartilage mineralization. Bone vol 17 issue 5 1996 8579957 |
these data indicate that the cellular processes involved in chrondrocyte hypertrophy were accelerated by icf, as well as the extracellular processes leading to matrix mineralization. |
1996-03-18 |
2023-01-24 |
mouse |
| B Maisch, C Brilla, T Kruse, B Noll, C Bethg. [Retrospective studies and prospects of therapy for hypertension]. Herz vol 20 issue 6 1996 8582697 |
important steps on that road are the prevention or reparation of cardiac hypertrophy, of the increased extracellular matrix and collagen deposition, the conservation of vascular integrity including both coronary and systemic microangiopathy and macroangiopathy. |
1996-03-15 |
2023-01-24 |
Not clear |
| K Shikata, H Makino, H Sugimoto, M Kushiro, K Ota, K Akiyama, N Araki, S Horiuchi, Z Ot. Localization of advanced glycation endproducts in the kidney of experimental diabetic rats. Journal of diabetes and its complications vol 9 issue 4 1996 8573744 |
in the diabetic rats, glomerular hypertrophy, thickening of the glomerular basement membrane, and expansion of mesangial matrix were observed. |
1996-03-13 |
2023-01-24 |
rat |
| R E Gilbert, P G McNally, A Cox, M Dziadek, J Rumble, M E Cooper, G Jerum. SPARC gene expression is reduced in early diabetes-related kidney growth. Kidney international vol 48 issue 4 1996 8569083 |
the biological processes involved in diabetes-related kidney growth are complex and involve changes in extracellular matrix, cell hypertrophy and hyperplasia. |
1996-03-01 |
2023-01-24 |
rat |
| M Takechi, C Itakur. Ultrastructural studies of the epiphyseal plate of chicks fed a vitamin D-deficient and low-calcium diet. Journal of comparative pathology vol 113 issue 2 1996 8543668 |
in this zone, hypertrophic chondrocytes responsible for the initial calcification were seen, but not the stellate chondrocytes responsible for the progression of matrix calcification after its initiation. |
1996-02-13 |
2023-01-24 |
Not clear |
| S A Brown, C A Brow. Single-nephron adaptations to partial renal ablation in cats. The American journal of physiology vol 269 issue 5 Pt 2 1996 7503284 |
these results demonstrate that increases in sngfr in feline remnant nephrons occur in association with glomerular hypertension, glomerular hypertrophy, expansion of mesangial matrix, and proteinuria, and furthermore, that the observed increases in sngfr are attributable to an augmentation of efpm and kf. |
1996-01-17 |
2023-01-24 |
Not clear |
| Q Chen, D M Johnson, D R Haudenschild, P F Goetinc. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. Developmental biology vol 172 issue 1 1995 7589809 |
we find that the postproliferative chondrocytes which make up the zone between the zones of proliferation and hypertrophy specifically transcribe the gene for cartilage matrix protein (cmp). |
1995-12-26 |
2023-01-24 |
Not clear |
| Q Chen, D M Johnson, D R Haudenschild, P F Goetinc. Progression and recapitulation of the chondrocyte differentiation program: cartilage matrix protein is a marker for cartilage maturation. Developmental biology vol 172 issue 1 1995 7589809 |
cmp translation products are present in the matrix surrounding the nonproliferative chondrocytes of both the zones of maturation and hypertrophy. |
1995-12-26 |
2023-01-24 |
Not clear |