| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M J Morgan, A J Madgwick, B Charleston, J M Pell, P T Loughn. The developmental regulation of a novel muscle LIM-protein. Biochemical and biophysical research communications. vol 212. issue 3. 1995-08-25. PMID:7626119. |
this period corresponds to the period of greatest muscle fibre hypertrophy and suggests a role for this homologue in either the elaboration of muscle fibre matrix anchorage or the regulation of muscle fibre hypertrophy itself. |
1995-08-25 |
2023-08-12 |
human |
| N J Mayer, S A Rubi. The molecular and cellular biology of heart failure. Current opinion in cardiology. vol 10. issue 3. 1995-08-18. PMID:7612972. |
in animal models, the hypothesis that the devolution from hypertrophy to heart failure includes alterations in the molecular direction of extracellular matrix production gained some support. |
1995-08-18 |
2023-08-12 |
Not clear |
| J H Omens, D E Milkes, J W Covel. Effects of pressure overload on the passive mechanics of the rat left ventricle. Annals of biomedical engineering. vol 23. issue 2. 1995-08-07. PMID:7605052. |
thus, in this model of pressure-overload hypertrophy, the decreases in compliance and circumferential strain of the passive lv are not due to changes in the percentage of extracellular matrix, but rather to global geometric changes. |
1995-08-07 |
2023-08-12 |
rat |
| H A Struijker-Boudier, J F Smits, J G De Me. Pharmacology of cardiac and vascular remodeling. Annual review of pharmacology and toxicology. vol 35. 1995-08-01. PMID:7598505. |
the most distinguished features of this process are phenotypic modulation of various cell types in the cardiovascular system; cellular hyperplasia and hypertrophy; and extracellular matrix production, deposition, and degradation. |
1995-08-01 |
2023-08-12 |
Not clear |
| A Ghahary, Y J Shen, P G Scott, E E Tredge. Immunolocalization of TGF-beta 1 in human hypertrophic scar and normal dermal tissues. Cytokine. vol 7. issue 2. 1995-07-18. PMID:7780038. |
following severe thermal injury and other injuries to the deep dermis of the skin, patients frequently develop hypertrophic scarring (hsc) which is characterized by an over-abundance of extracellular matrix (ecm) proteins including collagen. |
1995-07-18 |
2023-08-12 |
human |
| M Ketteler, N A Noble, W A Borde. Transforming growth factor-beta and angiotensin II: the missing link from glomerular hyperfiltration to glomerulosclerosis? Annual review of physiology. vol 57. 1995-07-13. PMID:7778869. |
recent studies reveal that angiotensin ii is a potent inducer of tgf-beta synthesis in a variety of cells and that this mechanism exerts important biological effects including extracellular matrix accumulation, cell proliferation, and hypertrophy. |
1995-07-13 |
2023-08-12 |
Not clear |
| F Descalzi Cancedda, A Melchiori, R Benelli, C Gentili, L Masiello, G Campanile, R Cancedda, A Albin. Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: dependence on extracellular matrix assembly. European journal of cell biology. vol 66. issue 1. 1995-06-20. PMID:7538466. |
supernatants from dedifferentiated cells undergoing maturation to hypertrophic chondrocytes in suspension progressively inhibited vascular cell random migration and invasion of basement membrane matrix by endothelial cells. |
1995-06-20 |
2023-08-12 |
mouse |
| F Descalzi Cancedda, A Melchiori, R Benelli, C Gentili, L Masiello, G Campanile, R Cancedda, A Albin. Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: dependence on extracellular matrix assembly. European journal of cell biology. vol 66. issue 1. 1995-06-20. PMID:7538466. |
medium conditioned by osteoblast-like cells derived from hypertrophic chondrocytes also induced vascular cell migration and invasion of basement membrane matrix. |
1995-06-20 |
2023-08-12 |
mouse |
| F Descalzi Cancedda, A Melchiori, R Benelli, C Gentili, L Masiello, G Campanile, R Cancedda, A Albin. Production of angiogenesis inhibitors and stimulators is modulated by cultured growth plate chondrocytes during in vitro differentiation: dependence on extracellular matrix assembly. European journal of cell biology. vol 66. issue 1. 1995-06-20. PMID:7538466. |
therefore, interactions of chondrocytes with their extracellular matrix are an absolute requirement for the expression of angiogenic activities by hypertrophic chondrocytes at late developmental stages. |
1995-06-20 |
2023-08-12 |
mouse |
| D Aeschlimann, O Kaupp, M Paulsso. Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: identification of osteonectin as a major glutaminyl substrate. The Journal of cell biology. vol 129. issue 3. 1995-05-31. PMID:7730416. |
we now demonstrate the transglutaminase reaction product, the gamma-glutamyl-epsilon-lysine cross-link, in the matrix of hypertrophic cartilage using a novel cross-link specific antibody. |
1995-05-31 |
2023-08-12 |
Not clear |
| D Aeschlimann, O Kaupp, M Paulsso. Transglutaminase-catalyzed matrix cross-linking in differentiating cartilage: identification of osteonectin as a major glutaminyl substrate. The Journal of cell biology. vol 129. issue 3. 1995-05-31. PMID:7730416. |
incorporation of the synthetic transglutaminase substrate monodansylcadaverine (amine donor) in cultured tracheal explants reveals enzyme activity in the pericellular matrix of hypertrophic chondrocytes in the central, calcifying areas of the horseshoe-shaped cartilages. |
1995-05-31 |
2023-08-12 |
Not clear |
| A M Garcia, M L Gra. Dimensional growth and extracellular matrix accumulation by neonatal rat mandibular condyles in long-term culture. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 13. issue 2. 1995-05-25. PMID:7722758. |
growth occurred by a combination of cell proliferation, matrix synthesis and accumulation, and cell hypertrophy (with the latter two mechanisms dominating). |
1995-05-25 |
2023-08-12 |
rat |
| T Sawai, J Fujiyama, M Takahashi, T Takahash. The site of elevated vascular resistance in early paraquat lungs: a morphometric study of pulmonary arteries. The Tohoku journal of experimental medicine. vol 174. issue 2. 1995-04-27. PMID:7900152. |
in paraquat lungs, dm began to rise as early as the 8th day, i.e., almost simultaneously with beginning deposition of fibrogenic matrix on alveolar wall, suggesting that the medial hypertrophy is the result of hypoxic vasoconstriction due to alveolar-capillary block. |
1995-04-27 |
2023-08-12 |
Not clear |
| D Chan, W G Cole, J G Rogers, J F Batema. Type X collagen multimer assembly in vitro is prevented by a Gly618 to Val mutation in the alpha 1(X) NC1 domain resulting in Schmid metaphyseal chondrodysplasia. The Journal of biological chemistry. vol 270. issue 9. 1995-04-05. PMID:7876225. |
it is a highly specialized extracellular matrix component, and its synthesis is restricted to hypertrophic chondrocytes in the calcifying cartilage of the growth plate and in zones of secondary ossification. |
1995-04-05 |
2023-08-12 |
Not clear |
| L Brown, C Serni. Angiotensin receptors in cardiovascular diseases. Clinical and experimental pharmacology & physiology. vol 21. issue 10. 1995-03-29. PMID:7867232. |
the cellular effects of aii are extensive and encompass hypertrophy, hyperplasia and the deposition of extracellular matrix. |
1995-03-29 |
2023-08-12 |
human |
| T Omura, S Kim, K Takeuchi, H Iwao, T Taked. Transforming growth factor beta 1 and extracellular matrix gene expression in isoprenaline induced cardiac hypertrophy: effects of inhibition of the renin-angiotensin system. Cardiovascular research. vol 28. issue 12. 1995-03-28. PMID:7867037. |
transforming growth factor beta 1 and extracellular matrix gene expression in isoprenaline induced cardiac hypertrophy: effects of inhibition of the renin-angiotensin system. |
1995-03-28 |
2023-08-12 |
Not clear |
| W O Twal, R Vasilatos-Younken, C V Gay, R M Leac. Isolation and localization of basic fibroblast growth factor-immunoreactive substance in the epiphyseal growth plate. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. vol 9. issue 11. 1995-03-20. PMID:7863825. |
basic fgf appears to be associated with the extracellular matrix of the proliferative zone, but it is predominantly intracellular in the hypertrophic and mineralizing zone chondrocytes. |
1995-03-20 |
2023-08-12 |
Not clear |
| G D Walker, M Fischer, J Gannon, R C Thompson, T R Oegem. Expression of type-X collagen in osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 13. issue 1. 1995-03-16. PMID:7853102. |
thus, the osteoarthritic process may damage the matrix in the superficial layer and induce changes leading to the expression of the hypertrophic chondrocyte phenotype. |
1995-03-16 |
2023-08-12 |
mouse |
| D Le Guellec, F Mallein-Gerin, I Treilleux, J Bonaventure, P Peysson, D Herbag. Localization of the expression of type I, II and III collagen genes in human normal and hypochondrogenesis cartilage canals. The Histochemical journal. vol 26. issue 9. 1995-03-03. PMID:7843983. |
the canal hypertrophy observed in this pathological case could thus be due to a modification in the regulation of the growth of cartilage canals caused by a defective cartilage matrix. |
1995-03-03 |
2023-08-12 |
human |
| V Lefebvre, S Garofalo, B de Crombruggh. Type X collagen gene expression in mouse chondrocytes immortalized by a temperature-sensitive simian virus 40 large tumor antigen. The Journal of cell biology. vol 128. issue 1-2. 1995-02-14. PMID:7822418. |
the cells from all pools and from most clones expressed the genes for several markers of hypertrophic chondrocytes, such as type x collagen, matrix gla protein, and osteopontin, but had lost expression of type ii collagen mrna and failed to be stained by alcian blue which detects cartilage-specific proteoglycans. |
1995-02-14 |
2023-08-12 |
mouse |