| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| F J Villarreal, N N Kim, G D Ungab, M P Printz, W H Dillman. Identification of functional angiotensin II receptors on rat cardiac fibroblasts. Circulation vol 88 issue 6 1994 8252698 |
cardiac hypertrophy results in an increased deposition of the extracellular matrix (ecm) proteins fibronectin and collagen. |
1994-01-13 |
2023-01-24 |
rat |
| W L Garner, S Karmiol, J L Rodriguez, D J Smith, S H Pha. Phenotypic differences in cytokine responsiveness of hypertrophic scar versus normal dermal fibroblasts. The Journal of investigative dermatology vol 101 issue 6 1994 8245516 |
the increased rate of collagen synthesis and decreased responsiveness to mitogens are consistent with the increased extracellular matrix content and decreased cellularity of hypertrophic scars. |
1994-01-06 |
2023-01-24 |
cattle |
| R J Wardale, V C Duanc. Quantification and immunolocalisation of porcine articular and growth plate cartilage collagens. Journal of cell science vol 105 ( Pt 4) issue 1993 8227218 |
types ii and xi are located in the matrix of both cartilages whereas type ix is predominantly pericellular in the calcifying region of articular cartilage and the hypertrophic region of the growth plate. |
1993-12-22 |
2023-01-24 |
Not clear |
| M Rintala, M Mets\\xc3\\xa4ranta, S Garofalo, B de Crombrugghe, E Vuorio, O R\\xc3\\xb6nnin. Abnormal craniofacial morphology and cartilage structure in transgenic mice harboring a Gly --> Cys mutation in the cartilage-specific type II collagen gene. Journal of craniofacial genetics and developmental biology vol 13 issue 3 1993 8227287 |
with the exception of the zone of hypertrophic chondrocytes the matrix also showed a loss of glycosaminoglycans. |
1993-12-17 |
2023-01-24 |
mouse |
| F N Ziyade. The extracellular matrix in diabetic nephropathy. American journal of kidney diseases : the official journal of the National Kidney Foundation vol 22 issue 5 1993 8238022 |
diabetic nephropathy is characterized by hypertrophy of both glomerular and tubular elements, progressive accumulation of extracellular matrix components in the glomerular mesangium, and thickening of the glomerular and tubular basement membranes. |
1993-12-08 |
2023-01-24 |
Not clear |
| C Dufour, L Carrier, C Hengstenberg, J Bercovici, E Dausse, J Weissenbach, O Dubourg, M Komajda, K Schwartz, J S Beckman. Exclusion of genes coding for proteins of the cytoskeleton and the extracellular matrix in familial hypertrophic cardiomyopathy using a candidate gene approach. Comptes rendus de l'Academie des sciences. Serie III, Sciences de la vie vol 316 issue 5 1993 8221230 |
exclusion of genes coding for proteins of the cytoskeleton and the extracellular matrix in familial hypertrophic cardiomyopathy using a candidate gene approach. |
1993-12-03 |
2023-01-24 |
human |
| G Plenz, Y Gan, H M Raabe, P K M\\xc3\\xbclle. Expression of vigilin in chicken cartilage and bone. Cell and tissue research vol 273 issue 2 1993 8364975 |
most striking is the correlation of the maximum vigilin mrna expression in osteoblasts and hypertrophic chondrocytes to periods when cell-specific genes were highly transcribed and substantially translated, e.g., synthesis of procollagen and formation of extracellular matrix in bone and cartilage. |
1993-10-07 |
2023-01-24 |
chicken |
| J Harper, E Harper, J W Covel. Collagen characterization in volume-overload- and pressure-overload-induced cardiac hypertrophy in minipigs. The American journal of physiology vol 265 issue 2 Pt 2 1993 8368345 |
pressure-overload- and volume-overload-induced cardiac hypertrophy in the pig produced different alterations in the extracellular matrix. |
1993-10-07 |
2023-01-24 |
Not clear |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry vol 52 issue 2 1993 8366137 |
induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. |
1993-10-05 |
2023-01-24 |
chicken |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry vol 52 issue 2 1993 8366137 |
several studies have raised the question of the possibility that the hypertrophic chondrocytes associated with the calcifying cartilage matrix can acquire properties similar to osteoblasts. |
1993-10-05 |
2023-01-24 |
chicken |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry vol 52 issue 2 1993 8366137 |
chondrocytes derived from chick embryo ventral vertebral tissue were cultured under conditions that promoted extracellular matrix mineralization and differentiation towards the hypertrophic phenotype as indicated by the induction of type x collagen, alkaline phosphatase, and diminished expression of type ii collagen and the core protein of large proteoglycan. |
1993-10-05 |
2023-01-24 |
chicken |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry vol 52 issue 2 1993 8366137 |
the coordinate change in the cellular phenotype to the hypertrophic chondrocyte was shown to be concurrent with ultrastructural maturation of the cells and the accumulation of osteocalcin and osteopontin in the extracellular matrix associated with hydroxyapatite at sites of mineralization. |
1993-10-05 |
2023-01-24 |
chicken |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry vol 52 issue 2 1993 8366137 |
since the ultrastructural features of the cells in vitro and the extracellular matrix surrounding the lacunae have features of the hypertrophic chondrocyte and associated matrix in vivo, the induction of the bone-specific protein osteocalcin suggests that at least a population of these cells may develop osteoblastic phenotypic markers in association with mineralizing matrix. |
1993-10-05 |
2023-01-24 |
chicken |
| R T Ballock, A Heydemann, L M Wakefield, K C Flanders, A B Roberts, M B Spor. TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. Developmental biology vol 158 issue 2 1993 8344460 |
tgf-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. |
1993-09-03 |
2023-01-24 |
rat |
| J E Bishop, J J Mitchell, P M Absher, L Baldor, H A Geller, J Woodcock-Mitchell, M J Hamblin, P Vacek, R B Lo. Cyclic mechanical deformation stimulates human lung fibroblast proliferation and autocrine growth factor activity. American journal of respiratory cell and molecular biology vol 9 issue 2 1993 8338682 |
cellular hypertrophy and hyperplasia and increased extracellular matrix deposition are features of tissue hypertrophy resulting from increased work load. |
1993-09-02 |
2023-01-24 |
human |
| Q Chen, J M Fitch, E Gibney, T F Linsenmaye. Type II collagen during cartilage and corneal development: immunohistochemical analysis with an anti-telopeptide antibody. Developmental dynamics : an official publication of the American Association of Anatomists vol 196 issue 1 1993 7687475 |
within the cartilaginous growth plate, the epitope disappears from the matrix soon after the chondrocytes become hypertrophic; within the cornea, the epitope disappears subjacent to the epithelium. |
1993-08-26 |
2023-01-24 |
Not clear |
| G L Bakris, J H Stei. Diabetic nephropathy. Disease-a-month : DM vol 39 issue 8 1993 8334915 |
specifically, antihypertensive agents are preferred that have natriuretic properties and also blunt the effects of vasoconstrictors on both the vasculature and the cellular level, i.e., inhibit mesangial hypertrophy and matrix expansion, the hallmark of diabetes. |
1993-08-26 |
2023-01-24 |
human |
| H Chiba, T Matsuyam. [Immunohistochemical localization of bone Gla protein and osteonectin in normal human bone and cartilage tissues, and in osteosarcomas and chondrosarcomas]. Nihon Seikeigeka Gakkai zasshi vol 67 issue 5 1993 8336066 |
in normal growth cartilage, on reacted with chondrocytes in hypertrophic and calcifying zone and matrix in calcifying zone, whereas bgp did not react. |
1993-08-25 |
2023-01-24 |
human |
| C Gentili, P Bianco, M Neri, M Malpeli, G Campanile, P Castagnola, R Cancedda, F D Cancedd. Cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. The Journal of cell biology vol 122 issue 3 1993 8393014 |
cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. |
1993-08-24 |
2023-01-24 |
chicken |
| J M Ledingham, J A Milla. Stereological studies on mesenteric resistance artery structure in New Zealand genetically hypertensive and control rats. Clinical and experimental pharmacology & physiology vol 20 issue 5 1993 8324924 |
these results show that media volume is increased in gh early in life, is not due to hyperplasia, but may be due to hypertrophy of the sm cells, an increase in the amount of extracellular matrix or a combination of both. |
1993-08-06 |
2023-01-24 |
rat |