| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| K Ishizeki, N Kuroda, H Nagano, T Naw. Morphological modifications during long-term survival of Meckel's cartilage hypertrophic chondrocytes transplanted in the mouse spleen. Archives of histology and cytology vol 55 issue 3 1992 1419276 |
hypertrophic chondrocytes, now exposed from cellular lacunae, and the osteocyte-like cells in the calcified matrix displayed involutional changes. |
1992-12-17 |
2023-01-23 |
mouse |
| R Quarto, G Campanile, R Cancedda, B Dozi. Thyroid hormone, insulin, and glucocorticoids are sufficient to support chondrocyte differentiation to hypertrophy: a serum-free analysis. The Journal of cell biology vol 119 issue 4 1992 1429844 |
when ascorbic acid is added to the hormone-supplemented medium, differentiating chondrocytes organize their matrix leading to a cartilage-like structure with hypertrophic chondrocytes embedded in lacunae. |
1992-12-04 |
2023-01-23 |
chicken |
| H I Roac. Trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix. Bone and mineral vol 19 issue 1 1992 1422302 |
trans-differentiation of hypertrophic chondrocytes into cells capable of producing a mineralized bone matrix. |
1992-12-03 |
2023-01-23 |
Not clear |
| Y Ben-Ami, D Lewinson, M Silberman. Structural characterization of the mandibular condyle in human fetuses: light and electron microscopy studies. Acta anatomica vol 145 issue 1 1992 1414216 |
the matrix in the hypertrophic cell layer reveals distinct matrix vesicles that undergo mineralization and subsequently coalesce to form larger sheets of mineralized extracellular matrix. |
1992-11-25 |
2023-01-23 |
human |
| S Jingushi, M E Joyce, M E Bolande. Genetic expression of extracellular matrix proteins correlates with histologic changes during fracture repair. Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research vol 7 issue 9 1992 1414497 |
messenger rnas for these proteins in the soft callus were detected at low levels during chondrogenesis (day 9) but increased to 80% of maximal levels with chondrocyte hypertrophy and mineralization of the cartilage matrix (day 13). |
1992-11-19 |
2023-01-23 |
rat |
| F Shapir. Vertebral development of the chick embryo during days 3-19 of incubation. Journal of morphology vol 213 issue 3 1992 1404404 |
clumps of growth plate cartilage cells and matrix are surrounded occasionally by newly synthesized bone, but invasion of individual hypertrophic chondrocyte lacunae by vessels with bone deposition by accompanying osteoblasts on single trabeculae of cartilage does not occur. |
1992-11-03 |
2023-01-23 |
chicken |
| M R Coe, T A Summers, S J Parsons, A L Boskey, G Balia. Matrix mineralization in hypertrophic chondrocyte cultures. Beta glycerophosphate increases type X collagen messenger RNA and the specific activity of pp60c-src kinase. Bone and mineral vol 18 issue 2 1992 1381978 |
matrix mineralization in hypertrophic chondrocyte cultures. |
1992-10-20 |
2023-01-23 |
Not clear |
| M R Coe, T A Summers, S J Parsons, A L Boskey, G Balia. Matrix mineralization in hypertrophic chondrocyte cultures. Beta glycerophosphate increases type X collagen messenger RNA and the specific activity of pp60c-src kinase. Bone and mineral vol 18 issue 2 1992 1381978 |
the phenomenon of chondrocyte hypertrophy is accompanied by the expression of type x collagen and the appearance of matrix mineralization. |
1992-10-20 |
2023-01-23 |
Not clear |
| T Kirsch, K von der Mar. Remodelling of collagen types I, II and X and calcification of human fetal cartilage. Bone and mineral vol 18 issue 2 1992 1525593 |
by immunofluorescence double staining we demonstrate codistribution of type ii and x collagen in the hypertrophic zone, while type i collagen was absent from hypertrophic cartilage matrix; it was detected only in the perichondrium, in vascular cavities, and in osteoid and bone. |
1992-10-20 |
2023-01-23 |
human |
| F J Villarreal, W H Dillman. Cardiac hypertrophy-induced changes in mRNA levels for TGF-beta 1, fibronectin, and collagen. The American journal of physiology vol 262 issue 6 Pt 2 1992 1535758 |
cardiac hypertrophy induced by pressure overload is accompanied by increases in the deposition of extracellular matrix (ecm) proteins. |
1992-08-04 |
2023-01-23 |
rat |
| M Miyamoto, H Koike, T Sada, Y Ijima, J Fukushige, N Nakamur. The effects of R-75,317 on antiglomerular basement membrane glomerulonephritis in rats. Lipids vol 26 issue 12 1992 1819723 |
histological changes in this model (glomerular hypertrophy, proliferation of mesangial matrix and interstitial fibrosis) were also ameliorated by the r-75,317 treatment. |
1992-07-30 |
2023-01-23 |
rat |
| T M Ganey, S M Love, J A Ogde. Development of vascularization in the chondroepiphysis of the rabbit. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 10 issue 4 1992 1613625 |
three distinct cartilage canal morphologies were identifiable before the formation of the secondary center of ossification: (a) an early phase, in which the canals appeared as infoldings derived from the perichondrium; (b) a reactive phase, occurring simultaneously with chondrocyte hypertrophy and characterized by a very large increase in mesenchymal cells within the cartilage canal; and (c) a vascular phase, coincident with mineralization of the matrix, in which the familiar, unitary canal morphology was replaced by that of a vascular plexus. |
1992-07-28 |
2023-01-23 |
human |
| T M Ganey, S M Love, J A Ogde. Development of vascularization in the chondroepiphysis of the rabbit. Journal of orthopaedic research : official publication of the Orthopaedic Research Society vol 10 issue 4 1992 1613625 |
while matrix mineralization and the formation of bone seem dependent on critical cellular events, notably chondrocyte hypertrophy, the role that the vascular supply plays in developing sufficient biological inertia for the ossifying transition must not be underestimated. |
1992-07-28 |
2023-01-23 |
human |
| H E Abbou. Growth factors and the mesangium. Journal of the American Society of Nephrology : JASN vol 2 issue 10 Suppl 1992 1600135 |
growth factors may promote hypertrophy, proliferation, matrix metabolism, and immune-inflammatory and vasoactive properties of mesangial cells. |
1992-07-15 |
2023-01-23 |
Not clear |
| A A Cole, L J Luchene, T F Linsenmayer, T M Schmi. The influence of bone and marrow on cartilage hypertrophy and degradation during 30-day serum-free culture of the embryonic chick tibia. Developmental dynamics : an official publication of the American Association of Anatomists vol 193 issue 3 1992 1600246 |
if the tibial cartilage is separated from the bony collar and cultured alone in serum-free medium, the nonhypertrophic chondrocytes also hypertrophy; the matrix loses safranin o staining; however, some components of the matrix including type x collagen still remain after 30 days. |
1992-07-10 |
2023-01-23 |
chicken |
| G D Angelini, A J Bryan, H M Williams, A A Soyombo, A Williams, J Tovey, A C Newb. Time-course of medial and intimal thickening in pig venous arterial grafts: relationship to endothelial injury and cholesterol accumulation. The Journal of thoracic and cardiovascular surgery vol 103 issue 6 1992 1597973 |
between 1 and 4 weeks after grafting, further rapid medial and intimal thickening occurred with no further increase in cell number but with a reduction in cell density, which suggested that cell migration, hypertrophy, and the laying down of extracellular matrix were responsible. |
1992-07-06 |
2023-01-23 |
Not clear |
| G D Angelini, A J Bryan, H M Williams, A A Soyombo, A Williams, J Tovey, A C Newb. Time-course of medial and intimal thickening in pig venous arterial grafts: relationship to endothelial injury and cholesterol accumulation. The Journal of thoracic and cardiovascular surgery vol 103 issue 6 1992 1597973 |
we conclude that three processes contribute to medial and intimal thickening, namely: (1) an initial phase of rapid smooth muscle cell proliferation, (2) smooth muscle cell migration, hypertrophy, and synthesis of extracellular matrix, and (3) a late phase of slower smooth muscle cell proliferation. |
1992-07-06 |
2023-01-23 |
Not clear |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international vol 50 issue 4 1992 1571844 |
calcification occurs in the extracellular matrix of the hypertrophic zone of the growth plate when the extracellular matrix volume is reduced to a minimum and alkaline phosphatase content is maximal. |
1992-06-03 |
2023-01-23 |
cattle |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international vol 50 issue 4 1992 1571844 |
the concentrations within the extracellular matrix of the c-propeptide of type ii collagen, aggregating proteoglycan (aggrecan), and hyaluronic acid all progressively increased in the maturing and hypertrophic zones, being maximal (or near maximal) at the time of initiation of mineralization. |
1992-06-03 |
2023-01-23 |
cattle |
| M Alini, Y Matsui, G R Dodge, A R Pool. The extracellular matrix of cartilage in the growth plate before and during calcification: changes in composition and degradation of type II collagen. Calcified tissue international vol 50 issue 4 1992 1571844 |
total collagen concentration (measured as hydroxyproline) in the extracellular matrix initially increased through the proliferating and maturing zones but then rapidly decreased in the hypertrophic zone. |
1992-06-03 |
2023-01-23 |
cattle |