| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry. vol 52. issue 2. 1993-10-05. PMID:8366137. |
the coordinate change in the cellular phenotype to the hypertrophic chondrocyte was shown to be concurrent with ultrastructural maturation of the cells and the accumulation of osteocalcin and osteopontin in the extracellular matrix associated with hydroxyapatite at sites of mineralization. |
1993-10-05 |
2023-08-12 |
chicken |
| J B Lian, M D McKee, A M Todd, L C Gerstenfel. Induction of bone-related proteins, osteocalcin and osteopontin, and their matrix ultrastructural localization with development of chondrocyte hypertrophy in vitro. Journal of cellular biochemistry. vol 52. issue 2. 1993-10-05. PMID:8366137. |
since the ultrastructural features of the cells in vitro and the extracellular matrix surrounding the lacunae have features of the hypertrophic chondrocyte and associated matrix in vivo, the induction of the bone-specific protein osteocalcin suggests that at least a population of these cells may develop osteoblastic phenotypic markers in association with mineralizing matrix. |
1993-10-05 |
2023-08-12 |
chicken |
| R T Ballock, A Heydemann, L M Wakefield, K C Flanders, A B Roberts, M B Spor. TGF-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. Developmental biology. vol 158. issue 2. 1993-09-03. PMID:8344460. |
tgf-beta 1 prevents hypertrophy of epiphyseal chondrocytes: regulation of gene expression for cartilage matrix proteins and metalloproteases. |
1993-09-03 |
2023-08-12 |
rat |
| J E Bishop, J J Mitchell, P M Absher, L Baldor, H A Geller, J Woodcock-Mitchell, M J Hamblin, P Vacek, R B Lo. Cyclic mechanical deformation stimulates human lung fibroblast proliferation and autocrine growth factor activity. American journal of respiratory cell and molecular biology. vol 9. issue 2. 1993-09-02. PMID:8338682. |
cellular hypertrophy and hyperplasia and increased extracellular matrix deposition are features of tissue hypertrophy resulting from increased work load. |
1993-09-02 |
2023-08-12 |
human |
| Q Chen, J M Fitch, E Gibney, T F Linsenmaye. Type II collagen during cartilage and corneal development: immunohistochemical analysis with an anti-telopeptide antibody. Developmental dynamics : an official publication of the American Association of Anatomists. vol 196. issue 1. 1993-08-26. PMID:7687475. |
within the cartilaginous growth plate, the epitope disappears from the matrix soon after the chondrocytes become hypertrophic; within the cornea, the epitope disappears subjacent to the epithelium. |
1993-08-26 |
2023-08-12 |
Not clear |
| G L Bakris, J H Stei. Diabetic nephropathy. Disease-a-month : DM. vol 39. issue 8. 1993-08-26. PMID:8334915. |
specifically, antihypertensive agents are preferred that have natriuretic properties and also blunt the effects of vasoconstrictors on both the vasculature and the cellular level, i.e., inhibit mesangial hypertrophy and matrix expansion, the hallmark of diabetes. |
1993-08-26 |
2023-08-12 |
human |
| H Chiba, T Matsuyam. [Immunohistochemical localization of bone Gla protein and osteonectin in normal human bone and cartilage tissues, and in osteosarcomas and chondrosarcomas]. Nihon Seikeigeka Gakkai zasshi. vol 67. issue 5. 1993-08-25. PMID:8336066. |
in normal growth cartilage, on reacted with chondrocytes in hypertrophic and calcifying zone and matrix in calcifying zone, whereas bgp did not react. |
1993-08-25 |
2023-08-12 |
human |
| C Gentili, P Bianco, M Neri, M Malpeli, G Campanile, P Castagnola, R Cancedda, F D Cancedd. Cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. The Journal of cell biology. vol 122. issue 3. 1993-08-24. PMID:8393014. |
cell proliferation, extracellular matrix mineralization, and ovotransferrin transient expression during in vitro differentiation of chick hypertrophic chondrocytes into osteoblast-like cells. |
1993-08-24 |
2023-08-12 |
chicken |
| J M Ledingham, J A Milla. Stereological studies on mesenteric resistance artery structure in New Zealand genetically hypertensive and control rats. Clinical and experimental pharmacology & physiology. vol 20. issue 5. 1993-08-06. PMID:8324924. |
these results show that media volume is increased in gh early in life, is not due to hyperplasia, but may be due to hypertrophy of the sm cells, an increase in the amount of extracellular matrix or a combination of both. |
1993-08-06 |
2023-08-12 |
rat |
| G K Hunter, D P Holmyard, K P Pritzke. Calcification of chick vertebral chondrocytes grown in agarose gels: a biochemical and ultrastructural study. Journal of cell science. vol 104 ( Pt 4). 1993-07-28. PMID:8314888. |
chick embryo vertebral chondrocytes (checov cells) grown in agarose gels form spherical colonies containing cells of hypertrophic morphology and a metachromatically staining matrix. |
1993-07-28 |
2023-08-12 |
chicken |
| S Inao, H E Conra. Type X collagen does not bind to matrix vesicles. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 68. issue 2. 1993-07-12. PMID:8509064. |
cultured chick embryo tibial hypertrophic chondrocytes released matrix vesicles and type x collagen into the culture medium. |
1993-07-12 |
2023-08-12 |
chicken |
| S Inao, H E Conra. Type X collagen does not bind to matrix vesicles. [Hokkaido igaku zasshi] The Hokkaido journal of medical science. vol 68. issue 2. 1993-07-12. PMID:8509064. |
these results indicate that matrix vesicles and type x collagen are not the associated products of hypertrophic chondrocyte. |
1993-07-12 |
2023-08-12 |
chicken |
| P Lu Valle, M Iwamoto, P Fanning, M Pacifici, B R Olse. Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. The Journal of cell biology. vol 121. issue 5. 1993-06-29. PMID:8501122. |
multiple negative elements in a gene that codes for an extracellular matrix protein, collagen x, restrict expression to hypertrophic chondrocytes. |
1993-06-29 |
2023-08-12 |
cat |
| P Lu Valle, M Iwamoto, P Fanning, M Pacifici, B R Olse. Multiple negative elements in a gene that codes for an extracellular matrix protein, collagen X, restrict expression to hypertrophic chondrocytes. The Journal of cell biology. vol 121. issue 5. 1993-06-29. PMID:8501122. |
mature hypertrophic chondrocytes differ from immature chondrocytes in that they become postmitotic, increase their cellular volume up to eightfold, and synthesize a unique set of matrix molecules. |
1993-06-29 |
2023-08-12 |
cat |
| J D Frank, R Balena, P Masarachia, J G Seedor, M E Cartwrigh. The effects of three different demineralization agents on osteopontin localization in adult rat bone using immunohistochemistry. Histochemistry. vol 99. issue 4. 1993-06-28. PMID:8500993. |
demineralization in modified jenkin's solution (16 days) showed osteopontin localization in bone matrix, hypertrophic and articular chondrocytes, and osteocytes. |
1993-06-28 |
2023-08-12 |
rat |
| J D Frank, R Balena, P Masarachia, J G Seedor, M E Cartwrigh. The effects of three different demineralization agents on osteopontin localization in adult rat bone using immunohistochemistry. Histochemistry. vol 99. issue 4. 1993-06-28. PMID:8500993. |
harsh, rapid demineralization with formic acid (4 days, room temperature) produced a loss in antigenicity demonstrated by a reduction in staining intensity not experienced with the 4 degrees c protocol; however, osteopontin was still localized in bone matrix and hypertrophic zone chondrocytes. |
1993-06-28 |
2023-08-12 |
rat |
| A H Plaas, J D Sand. A cartilage explant system for studies on aggrecan structure, biosynthesis and catabolism in discrete zones of the mammalian growth plate. Matrix (Stuttgart, Germany). vol 13. issue 2. 1993-06-15. PMID:8492742. |
these observations are discussed in terms of the role of aggrecan in the extensive matrix remodelling which accompanies chondrocyte hypertrophy in the growth plate. |
1993-06-15 |
2023-08-12 |
cattle |
| D Wilson, P K Paul, E D Roberts, V Blancuzzi, J Gronlund-Jacob, K Vosbeck, G DiPasquale, E M O'Byrn. Magnetic resonance imaging and morphometric quantitation of cartilage histology after chronic infusion of interleukin 1 in rabbit knees. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 203. issue 1. 1993-05-20. PMID:8475136. |
histology revealed a loss of staining of cartilage matrix proteoglycan, synovial hypertrophy, and perichondral bone resorption. |
1993-05-20 |
2023-08-12 |
rabbit |
| M Grandolfo, P D'Andrea, S Paoletti, M Martina, G Silvestrini, E Bonucci, F Vittu. Culture and differentiation of chondrocytes entrapped in alginate gels. Calcified tissue international. vol 52. issue 1. 1993-04-22. PMID:8453503. |
during the culture time, the chondrocytes undergo differentiation as it is demonstrated by the alkaline phosphatase specific activity increase and by morphological criteria (hypertrophy, increase of the number of mitochondria per cell, increased endoplasmic reticulum, matrix vesicle production). |
1993-04-22 |
2023-08-12 |
Not clear |
| N Makino, H Matsui, K Masutomo, T Hata, T Yanag. Effect of angiotensin converting enzyme inhibitor on regression in cardiac hypertrophy. Molecular and cellular biochemistry. vol 119. issue 1-2. 1993-04-20. PMID:8384300. |
effects of enalapril on extracellular matrix in the myocardium was also observed in regression of hypertrophy in which the type iii collagen mrna expression and collagen contents were reduced in comparison with those of hypertrophied myocardium. |
1993-04-20 |
2023-08-12 |
rat |