| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| J C Kim, L S Kaminsk. 2,2,2-Trifluoroethanol toxicity in hamsters (Mesocricetus auratus). Toxicologic pathology vol 15 issue 4 1988 3432941 |
the major lesions observed were severe hepatocyte hyperplasia and hypertrophy with fatty degeneration, necrosis of hair germinal matrix, urinary bladder transitional epithelial cellular hypertrophy, and hyperplasia with vacuolar degeneration and submucosal edema. |
1988-03-14 |
2023-01-24 |
Not clear |
| G Maor, K von der Mark, H Reddi, D Heineg\\xc3\\xa5rd, A Franzen, M Silberman. Acceleration of cartilage and bone differentiation on collagenous substrata. Collagen and related research vol 7 issue 5 1988 3319377 |
after 24 h in culture, new chondroblasts developed which subsequently matured showing signs of hypertrophy, while the extracellular matrix revealed positive reactivity for type ii collagen, cartilage proteoglycans and mineralization. |
1988-01-29 |
2023-01-24 |
Not clear |
| J A Buckwalter, L C Rosenberg, R Unga. Changes in proteoglycan aggregates during cartilage mineralization. Calcified tissue international vol 41 issue 4 1988 3119178 |
thus, before the cartilage matrix mineralized in the lower proliferative zone and as the cartilage matrix began to mineralize in the hypertrophic zone, proteoglycan aggregate size decreased and the proportion of aggregated monomers decreased. |
1988-01-05 |
2023-01-24 |
cattle |
| M N Campos, A R Cru. Relative growth of the condylar cartilage of the rat mandibular head during postnatal life. Gegenbaurs morphologisches Jahrbuch vol 133 issue 4 1987 3678782 |
the approximate 15% decrease of the cell contingent, the approximate 48% increase in cartilage matrix, the abrupt changes in the descriptive curve around the 15th to 20th d of postnatal life and the analysis of the relative growth pattern of the fibrous, embryogenic, cartilage, and hypertrophic cartilage layers were related to the functional adaptations which regulate the growth of the mandible condyle by a direct or indirect action on the temporal-mandibular articulation system. |
1987-12-21 |
2023-01-24 |
rat |
| E Livne, C Oliver, R D Leapman, L C Rosenberg, A R Poole, M Silberman. Age-related changes in the role of matrix vesicles in the mandibular condylar cartilage. Journal of anatomy vol 150 issue 1987 3308799 |
in one week old animals the most intense staining was observed in the matrix around the hypertrophic cells in the mineralising zone, to a lesser degree around the cells in the zone of chondroblasts, while no staining was noted in the zone of chondroprogenitor cells and in the matrix around the early hypertrophic cells. |
1987-11-16 |
2023-01-24 |
mouse |
| E Livne, C Oliver, R D Leapman, L C Rosenberg, A R Poole, M Silberman. Age-related changes in the role of matrix vesicles in the mandibular condylar cartilage. Journal of anatomy vol 150 issue 1987 3308799 |
the matrix between the early hypertrophic cells as shown by transmission electron microscopy revealed the presence of matrix vesicles and demonstrated a gradual accumulation of hydroxyapatite in the mineralising zone. |
1987-11-16 |
2023-01-24 |
mouse |
| J Wroblewsk. Elemental changes associated with chondrocyte differentiation in rat rib growth plate. Histochemistry vol 87 issue 2 1987 3623998 |
levels of na, p, s, cl, k, and ca were determined in the cells and extracellular matrix in different zones of the cartilage--resting, proliferative, and hypertrophic. |
1987-10-22 |
2023-01-24 |
rat |
| E Vignon, J Bejui, P Mathieu, J D Hartmann, G Ville, J C Evreux, J Descote. Histological cartilage changes in a rabbit model of osteoarthritis. The Journal of rheumatology vol 14 Spec No issue 1987 3625662 |
histological changes including cartilage hypertrophy, reduced cell density, matrix alterations, cystic lesions, and enlarged perichondrocytic lacunae were found to precede cartilage fibrillation. |
1987-10-05 |
2023-01-24 |
rabbit |
| W T Grant, G J Wang, G Balia. Type X collagen synthesis during endochondral ossification in fracture repair. The Journal of biological chemistry vol 262 issue 20 1987 3597444 |
type x synthesis occurred in the areas of cartilaginous callus composed of hypertrophic and degenerative chondrocytes that were associated with increased vascularity and matrix mineralization. |
1987-08-13 |
2023-01-24 |
chicken |
| P Hadjiisky, N Peyri, Y Grosgogea. Tunica media changes in the spontaneously hypertensive rat (SHR). Atherosclerosis vol 65 issue 1-2 1987 3606728 |
it seems due to three processes: early generalized hypertrophy of smooth muscle cells (smc); connective matrix neogenesis and smc proliferation, more evident in peripheral vasculature. |
1987-08-10 |
2023-01-24 |
rat |
| M Jayo, H W Leipold, S M Dennis, F E Eldridg. Brachygnathia superior and degenerative joint disease: a new lethal syndrome in Angus calves. Veterinary pathology vol 24 issue 2 1987 3576909 |
growth plates had defective chondrocyte proliferation and hypertrophy with aberrant ossification of calcified cartilaginous matrix. |
1987-05-22 |
2023-01-24 |
Not clear |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume vol 69 issue 2 1987 3543020 |
the two most prominent stages are those of cellular proliferation and hypertrophy (including the mineralization of matrix) before the resorption of tissue during vascular invasion. |
1987-03-23 |
2023-01-24 |
rat |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume vol 69 issue 2 1987 3543020 |
by applying recently developed stereological procedures and improved methods for the fixation of cartilage, we compared cellular shape modulation, various ultrastructural parameters (surface areas or volumes of endoplasmic reticulum, golgi membranes, and mitochondria), the production of matrix, and cellular turnover for proliferating and hypertrophic chondrocytes within the proximal tibial growth plate of the rat. |
1987-03-23 |
2023-01-24 |
rat |
| E B Hunziker, R K Schenk, L M Cruz-Oriv. Quantitation of chondrocyte performance in growth-plate cartilage during longitudinal bone growth. The Journal of bone and joint surgery. American volume vol 69 issue 2 1987 3543020 |
by the late hypertrophic stage, fourfold and tenfold increases in the mean cellular height and volume, respectively, and a threefold increase in the mean volume of the matrix per cell were achieved. |
1987-03-23 |
2023-01-24 |
rat |
| S D Boden, F S Kaplan, M D Fallon, R Ruddy, J Belik, E Anday, E Zackai, J Elli. Metatropic dwarfism. Uncoupling of endochondral and perichondral growth. The Journal of bone and joint surgery. American volume vol 69 issue 2 1987 3805078 |
other observations included prominence of the cartilaginous canals and vascular channels in the reserve zone; clumping of chondrocytes with enhanced staining of the pericellular matrix in the proliferative zone; a decreased ratio of cells to matrix in the hypertrophic zone, with intracellular metachromatic granules and incomplete evolution of chondrocytes; complete absence of an alcian-blue-positive zone of provisional calcification; and, finally, islands of dysplastic chondrocytes in the metaphysis. |
1987-03-23 |
2023-01-24 |
Not clear |
| M E Rosenfeld, T Tsukada, A Chait, E L Bierman, A M Gown, R Ros. Fatty streak expansion and maturation in Watanabe Heritable Hyperlipemic and comparably hypercholesterolemic fat-fed rabbits. Arteriosclerosis (Dallas, Tex.) vol 7 issue 1 1987 3813974 |
in both groups of animals, the fatty streaks expanded due to: 1) the formation of multiple layers of a mixed population of macrophage-derived foam cells and lipid-containing smooth muscle cells, 2) the hypertrophy of the macrophage-derived foam cells, 3) the continued accumulation of extracellular matrix, 4) the insudation of plasma components. |
1987-03-17 |
2023-01-24 |
Not clear |
| K T Weber, J S Janicki, R Pick, C Abrahams, S G Shroff, R I Bashey, R M Che. Collagen in the hypertrophied, pressure-overloaded myocardium. Circulation vol 75 issue 1 Pt 2 1987 2947751 |
the functional consequences of a remodeling of the collagen matrix that accompanied myocardial hypertrophy remain to be elucidated. |
1987-02-05 |
2023-01-23 |
Not clear |
| L A de Freitas, M Chevallier, D Louis, J A Grimau. Human extrahepatic biliary atresia: portal connective tissue activation related to ductular proliferation. Liver vol 6 issue 5 1987 3537604 |
the connective matrix pattern observed in periductular areas can be compared to that described in cicatricial and hypertrophic processes where the myofibroblastic cell population is known to play an important role in fibrosis development. |
1987-01-20 |
2023-01-24 |
human |
| N Kawabe, M G Ehrlich, H J Manki. In vivo degradation systems of the epiphyseal cartilage. Clinical orthopaedics and related research vol issue 211 1986 3769264 |
accumulated evidence suggests that in the growth cartilage during endochondral ossification, proteoglycans in the extracellular matrix of the lower hypertrophic zone are degraded by proteases and removed before mineralization. |
1986-12-01 |
2023-01-24 |
human |
| B de Bernard, P Bianco, E Bonucci, M Costantini, G C Lunazzi, P Martinuzzi, C Modricky, L Moro, E Panfili, P Pollesell. Biochemical and immunohistochemical evidence that in cartilage an alkaline phosphatase is a Ca2+-binding glycoprotein. The Journal of cell biology vol 103 issue 4 1986 3771650 |
in the cartilage plate, between the proliferating and the hypertrophic region, a weak immune reactivity is seen in the cytoplasm, whereas in the intercolumnar matrix the collagen fibers appear clearly stained. |
1986-11-26 |
2023-01-24 |
Not clear |