| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jonas M Hebel, Michael Lanz, Thomas Malina, Stefan R G Stodieck, Michel Le Van Quye. Effects of midazolam on high-frequency oscillations in amygdala and hippocampus of epilepsy patients. Epilepsia. 2024-02-17. PMID:38366848. |
considering the important role of interneuron activity in physiological hfo generation, we studied their modulation by midazolam (mdz), an agonist of γ-aminobutyric acid type a (gaba |
2024-02-17 |
2024-02-19 |
Not clear |
| Jennifer A Cale, Ethan J Chauhan, Joshua J Cleaver, Anthoio R Fusciardi, Sophie McCann, Hannah C Waters, Juš Žavbi, Madeleine V Kin. GABAergic and inflammatory changes in the frontal cortex following neonatal PCP plus isolation rearing, as a dual-hit neurodevelopmental model for schizophrenia. Molecular neurobiology. 2024-02-16. PMID:38363536. |
we recently showed that male lister-hooded rats exposed to pcp-iso exhibit reduced hippocampal expression of the gaba interneuron marker calbindin. |
2024-02-16 |
2024-02-18 |
rat |
| Satoshi Kosukegawa, Yuka Nakaya, Satomi Kobayashi, Kohei Kitano, Sachie Matsumura, Shohei Ogisawa, Manabu Zama, Mitsuru Motoyoshi, Masayuki Kobayash. Insulin facilitates synaptic transmission via gap junctions between fast-spiking interneurons in the rat insular cortex. Journal of oral science. 2023-02-23. PMID:36823134. |
inhibitory synaptic currents from fast-spiking neurons (fsns), a typical gamma-aminobutyric acid (gaba)ergic interneuron in the cerebral cortex, to pyramidal neurons are facilitated by insulin. |
2023-02-23 |
2023-08-14 |
rat |
| Hongzhu Li, Lanfeng Lai, Xin Li, Runyi Wang, Xiaoling Fang, Nenggui Xu, Jiaying Zha. Electroacupuncture Ameliorates Cognitive Impairment by Regulating γ-Amino Butyric Acidergic Interneurons in the Hippocampus of 5 Familial Alzheimer's Disease Mice. Neuromodulation : journal of the International Neuromodulation Society. 2023-01-05. PMID:36604241. |
because electroacupuncture (ea) treatment has been used for a complementary alternative medicine therapy in patients with ad, we aimed to examine any usefulness of ea therapy in gaba interneuron function and its associated synaptic proteins, to determine whether ea could effectively improve inhibitory transmission and network oscillation and eventually alleviate cognitive impairments in 5xfad mice, and to further elucidate the gabaergic system function underlying the antidementia response of ea. |
2023-01-05 |
2023-08-14 |
mouse |
| Stephen J Kaar, Judith F Nottage, Ilinca Angelescu, Tiago Reis Marques, Oliver D Howe. Gamma Oscillations and Potassium Channel Modulation in Schizophrenia: Targeting GABAergic Dysfunction. Clinical EEG and neuroscience. 2023-01-02. PMID:36591873. |
impairments in gamma-aminobutyric acid (gabaergic) interneuron function lead to gamma power abnormalities and are thought to underlie symptoms in people with schizophrenia. |
2023-01-02 |
2023-08-14 |
Not clear |
| Ludmila Lima-Silveira, Eileen M Hasser, David D Klin. Cardiovascular deconditioning increases GABA signaling in the nucleus tractus solitarii. Journal of neurophysiology. 2022-06-01. PMID:35642806. |
in response to gaba interneuron stimulation the evoked inhibitory postsynaptic current (nts-ipsc) amplitude and area, as well as igabasnfr fluorescence, was greater in hu than control. |
2022-06-01 |
2023-08-13 |
rat |
| Ludmila Lima-Silveira, Eileen M Hasser, David D Klin. Altered GABAergic neurotransmission at the nucleus tractus solitarii following Hindlimb Unloading. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554411. |
in response to gaba interneuron stimulation the evoked ipsc amplitude and area, as well as igabasnfr fluorescence, was greater in hu than control. |
2022-05-13 |
2023-08-13 |
rat |
| Deborah J Luessen, Isabel Gallinger, P J Con. mGlu FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35554597. |
furthermore, adolescent exposure to psychostimulants impairs gaba interneuron function and inhibitory transmission in the pfc in adulthood, suggesting that enhancing pfc inhibitory transmission may be a promising strategy to mitigate drug-induced cognitive deficits observed later in life. |
2022-05-13 |
2023-08-13 |
Not clear |
| Sunanjay Bajaj, Joshua A Bagley, Christoph Sommer, Abel Vertesy, Sakurako Nagumo Wong, Veronica Krenn, Julie Lévi-Strauss, Juergen A Knoblic. Neurotransmitter signaling regulates distinct phases of multimodal human interneuron migration. The EMBO journal. vol 40. issue 23. 2021-12-10. PMID:34661293. |
we use scrnaseq to reveal expression of gaba, glutamate, glycine, and serotonin receptors along distinct maturation trajectories across interneuron migration. |
2021-12-10 |
2023-08-13 |
human |
| Xin Wei, Selin Jessa, Claudia L Kleinman, Timothy N Phoeni. Mapping Angiopoietin1 Expression in the Developing and Adult Brain. Developmental neuroscience. vol 43. issue 6. 2021-12-03. PMID:34348288. |
in the developing brain, angpt1 displays specific spatiotemporal patterns, with strong expression in cerebellar gaba interneuron progenitors and, to a lower level, in glial progenitor and astrocyte lineages. |
2021-12-03 |
2023-08-13 |
mouse |
| Ashleigh Willis, Judith A Pratt, Brian J Morri. BDNF and JNK Signaling Modulate Cortical Interneuron and Perineuronal Net Development: Implications for Schizophrenia-Linked 16p11.2 Duplication Syndrome. Schizophrenia bulletin. vol 47. issue 3. 2021-11-22. PMID:33067994. |
sz is characterized by cortical gamma-amino-butyric acid (gaba)ergic interneuron dysfunction and disruption to surrounding extracellular matrix structures, perineuronal nets (pnns). |
2021-11-22 |
2023-08-13 |
mouse |
| Florent Marguet, Gaëlle Friocourt, Mélanie Brosolo, Fanny Sauvestre, Pascale Marcorelles, Céline Lesueur, Stéphane Marret, Bruno J Gonzalez, Annie Laquerrièr. Prenatal alcohol exposure is a leading cause of interneuronopathy in humans. Acta neuropathologica communications. vol 8. issue 1. 2021-11-09. PMID:33256853. |
we also focused on interneuron vascular migration along the cortical microvessels by confocal microscopy with double immunolabellings using glut1, gaba and calretinin. |
2021-11-09 |
2023-08-13 |
mouse |
| Amanda Kiemes, Felipe V Gomes, Diana Cash, Daniela L Uliana, Camilla Simmons, Nisha Singh, Anthony C Vernon, Federico Turkheimer, Cathy Davies, James M Stone, Anthony A Grace, Gemma Modino. GABA Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2021-11-07. PMID:34743200. |
gaba hippocampal hyperactivity driven by gabaergic interneuron deficits and nmda receptor hypofunction is associated with the hyperdopaminergic state often observed in schizophrenia. |
2021-11-07 |
2023-08-13 |
rat |
| Guadalupe Martínez-Lorenzana, Lourdes Palma-Tirado, Carmen Cifuentes-Diaz, Abimael González-Hernández, Miguel Condés-Lar. Ultrastructural Evidence for Oxytocin and Oxytocin Receptor at the Spinal Dorsal Horn: Mechanism of Nociception Modulation. Neuroscience. vol 475. 2021-10-21. PMID:34530103. |
this inhibitory action could be direct or use a gaba interneuron. |
2021-10-21 |
2023-08-13 |
rat |
| Cécile Léger, Nicolas Dupré, Annie Laquerrière, Maryline Lecointre, Marion Dumanoir, François Janin, Michelle Hauchecorne, Maëlle Fabre, Sylvie Jégou, Thierry Frébourg, Carine Cleren, Philippe Leroux, Pascale Marcorelles, Carole Brasse-Lagnel, Stéphane Marret, Florent Marguet, Bruno J Gonzale. In utero alcohol exposure exacerbates endothelial protease activity from pial microvessels and impairs GABA interneuron positioning. Neurobiology of disease. vol 145. 2021-10-12. PMID:32890773. |
in utero alcohol exposure exacerbates endothelial protease activity from pial microvessels and impairs gaba interneuron positioning. |
2021-10-12 |
2023-08-13 |
mouse |
| Cécile Léger, Nicolas Dupré, Annie Laquerrière, Maryline Lecointre, Marion Dumanoir, François Janin, Michelle Hauchecorne, Maëlle Fabre, Sylvie Jégou, Thierry Frébourg, Carine Cleren, Philippe Leroux, Pascale Marcorelles, Carole Brasse-Lagnel, Stéphane Marret, Florent Marguet, Bruno J Gonzale. In utero alcohol exposure exacerbates endothelial protease activity from pial microvessels and impairs GABA interneuron positioning. Neurobiology of disease. vol 145. 2021-10-12. PMID:32890773. |
in addition, the vascular system is known to contribute to controlling gamma-aminobutyric acid (gaba)ergic interneuron migration in the developing neocortex. |
2021-10-12 |
2023-08-13 |
mouse |
| Joshua T Kantrowitz, Zhengchao Dong, Matthew S Milak, Rain Rashid, Lawrence S Kegeles, Daniel C Javitt, Jeffrey A Lieberman, J John Man. Ventromedial prefrontal cortex/anterior cingulate cortex Glx, glutamate, and GABA levels in medication-free major depressive disorder. Translational psychiatry. vol 11. issue 1. 2021-10-11. PMID:34354048. |
gaba levels or gabaergic interneuron numbers are generally low in mdd, potentially disinhibiting glu release. |
2021-10-11 |
2023-08-13 |
Not clear |
| Meredith Lodge, Maria-Clemencia Hernandez, Jan M Schulz, Josef Bischofberge. Sparsification of AP firing in adult-born hippocampal granule cells via voltage-dependent α5-GABA Cell reports. vol 37. issue 1. 2021-10-05. PMID:34610304. |
surprisingly, both interneuron subtypes activate α5-subunit-containing gaba |
2021-10-05 |
2023-08-13 |
Not clear |
| Joseph Pottackal, Joshua H Singer, Jonathan B Dem. Computational and Molecular Properties of Starburst Amacrine Cell Synapses Differ With Postsynaptic Cell Type. Frontiers in cellular neuroscience. vol 15. 2021-09-25. PMID:34381333. |
the sac is a non-spiking interneuron that co-releases gaba and acetylcholine and forms closely spaced (<5 μm) inhibitory synapses onto two postsynaptic cell types: ds ganglion cells (dsgcs) and neighboring sacs. |
2021-09-25 |
2023-08-13 |
mouse |
| Stephen C Canno. Epilepsy channelopathies go neddy: stabilizing NaV1.1 channels by neddylation. The Journal of clinical investigation. vol 131. issue 8. 2021-09-20. PMID:33855971. |
pursuing the possibility that this phenotype is also caused by loss of nav1.1, chen, luo, gao, and colleagues show that interneuron excitability and gaba release are impaired, nav1.1 degradation rate is increased with a commensurate decrease of nav1.1 protein, and nav1.1 is a substrate for neddylation. |
2021-09-20 |
2023-08-13 |
mouse |