| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Y Hayashi, Y Tomimatsu, H Suzuki, J Yamada, Z Wu, H Yao, Y Kagamiishi, N Tateishi, M Sawada, H Nakanish. The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats. Neuroscience. vol 142. issue 1. 2006-12-20. PMID:16844302. |
these observations strongly suggest that the arterial-injection of microglia protected ca1 neurons against the ischemia-induced neuronal degeneration. |
2006-12-20 |
2023-08-12 |
rat |
| Y Hayashi, Y Tomimatsu, H Suzuki, J Yamada, Z Wu, H Yao, Y Kagamiishi, N Tateishi, M Sawada, H Nakanish. The intra-arterial injection of microglia protects hippocampal CA1 neurons against global ischemia-induced functional deficits in rats. Neuroscience. vol 142. issue 1. 2006-12-20. PMID:16844302. |
the restoration of the ischemia-induced synaptic deficits and the resultant reduction of the bdnf levels in ca1 neurons, possibly by the release of diffusible factor(s), might thus contribute to the protective effect of the arterial-injection of microglia against ischemia-induced neuronal degeneration. |
2006-12-20 |
2023-08-12 |
rat |
| Keun-Hwa Jung, Kon Chu, Soon-Tae Lee, Juhyun Kim, Dong-In Sinn, Jeong-Min Kim, Dong-Kyu Park, Jung-Ju Lee, Seung U Kim, Manho Kim, Sang Kun Lee, Jae-Kyu Ro. Cyclooxygenase-2 inhibitor, celecoxib, inhibits the altered hippocampal neurogenesis with attenuation of spontaneous recurrent seizures following pilocarpine-induced status epilepticus. Neurobiology of disease. vol 23. issue 2. 2006-11-27. PMID:16806953. |
during the latent period, celecoxib prevented neuronal death and microglia activation in the hilus and ca1 and inhibited the generation of ectopic granule cells in the hilus and new glia in ca1. |
2006-11-27 |
2023-08-12 |
human |
| In Koo Hwang, Ki-Yeon Yoo, Dae Won Kim, Soo Young Choi, Tae-Cheon Kang, Yong-Sun Kim, Moo Ho Wo. Ionized calcium-binding adapter molecule 1 immunoreactive cells change in the gerbil hippocampal CA1 region after ischemia/reperfusion. Neurochemical research. vol 31. issue 7. 2006-10-03. PMID:16841189. |
iba-1-immunoreactive cells in the ischemic ca1 region were co-localized with ox-42, a microglia marker. |
2006-10-03 |
2023-08-12 |
Not clear |
| Yoshinori Hayashi, Hitoshi Ishibashi, Kenji Hashimoto, Hiroshi Nakanish. Potentiation of the NMDA receptor-mediated responses through the activation of the glycine site by microglia secreting soluble factors. Glia. vol 53. issue 6. 2006-05-16. PMID:16498631. |
to elucidate the mechanism underlying the potentiation of nmda receptor-mediated responses by microglia, we examined the effects of mcm on nmda-induced inward currents in mechanically dissociated hippocampal ca1 neurons under whole-cell patch recordings. |
2006-05-16 |
2023-08-12 |
Not clear |
| In Koo Hwang, Ki-Yeon Yoo, Young Sam Nam, Jung Hoon Choi, In Se Lee, Young-Guen Kwon, Tae-Cheon Kang, Yong-Sun Kim, Moo Ho Wo. Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult. Neuroscience research. vol 54. issue 4. 2006-05-10. PMID:16473422. |
mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal ca1 region after ischemic insult. |
2006-05-10 |
2023-08-12 |
Not clear |
| In Koo Hwang, Ki-Yeon Yoo, Young Sam Nam, Jung Hoon Choi, In Se Lee, Young-Guen Kwon, Tae-Cheon Kang, Yong-Sun Kim, Moo Ho Wo. Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult. Neuroscience research. vol 54. issue 4. 2006-05-10. PMID:16473422. |
from 4 days after ischemia, mr and gr immunoreactivities were detected in astrocytes and microglia in the ca1 region, and at 7 days after ischemia, mr and gr immunoreactivities peaked in the hippocampal ca1 region. |
2006-05-10 |
2023-08-12 |
Not clear |
| In Koo Hwang, Ki-Yeon Yoo, Young Sam Nam, Jung Hoon Choi, In Se Lee, Young-Guen Kwon, Tae-Cheon Kang, Yong-Sun Kim, Moo Ho Wo. Mineralocorticoid and glucocorticoid receptor expressions in astrocytes and microglia in the gerbil hippocampal CA1 region after ischemic insult. Neuroscience research. vol 54. issue 4. 2006-05-10. PMID:16473422. |
in conclusion, enhanced mr and gr expressions in astrocytes and microglia were detected in the hippocampal ca1 region 4-7 days after ischemia/reperfusion. |
2006-05-10 |
2023-08-12 |
Not clear |
| Zhongmin Xiang, Vahram Haroutunian, Lap Ho, Dushant Purohit, Giulio Maria Pasinett. Microglia activation in the brain as inflammatory biomarker of Alzheimer's disease neuropathology and clinical dementia. Disease markers. vol 22. issue 1-2. 2006-03-17. PMID:16410654. |
in the hippocampus, a significant increase in microglia immunostaining was found in the pyramidal cell layer of ca1 as early as cdr 1, and in the upper molecular layer of the dentate gyrus in cdr 0.5. |
2006-03-17 |
2023-08-12 |
human |
| Sang-Ho Choi, Da Yong Lee, Seung Up Kim, Byung Kwan Ji. Thrombin-induced oxidative stress contributes to the death of hippocampal neurons in vivo: role of microglial NADPH oxidase. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 25. issue 16. 2006-02-14. PMID:15843610. |
in parallel, thrombin-activated microglia, assessed by ox-42 and ox-6 immunohistochemistry, and ros production, assessed by hydroethidine histochemistry, were observed in the hippocampal ca1 area in which degeneration of hippocampal neurons occurred. |
2006-02-14 |
2023-08-12 |
Not clear |
| Jeong-Sun Choi, Ha-Young Kim, Jin-Woong Chung, Myung-Hoon Chun, Seong Yun Kim, Shin-Hee Yoon, Mun-Yong Le. Activation of Src tyrosine kinase in microglia in the rat hippocampus following transient forebrain ischemia. Neuroscience letters. vol 380. issue 1-2. 2005-07-28. PMID:15854740. |
by day 3, active src expression markedly increased in the pyramidal cell layer of ca1 and the dentate hilar region in temporal correlation with neuronal cell death occurring in these areas, where cells typical of phagocytic microglia showed phospho-src immunoreactivity. |
2005-07-28 |
2023-08-12 |
rat |
| Sang Won Suh, Yang Fan, Shwuhuey M Hong, Zhengyan Liu, Yasuhiko Matsumori, Philip R Weinstein, Raymond A Swanson, Jialing Li. Hypoglycemia induces transient neurogenesis and subsequent progenitor cell loss in the rat hippocampus. Diabetes. vol 54. issue 2. 2005-04-11. PMID:15677508. |
no neuronal regeneration was observed in the ca1 after hypoglycemia, although dividing cells appeared to be astroglia or microglia in ca1 and dentate hilus. |
2005-04-11 |
2023-08-12 |
rat |
| In Koo Hwang, Ki-Yeon Yoo, Duk Soo Kim, Seon-Gil Do, Yang-Seok Oh, Tae-Cheon Kang, Byoung Hee Han, Jong Sung Kim, Moo Ho Wo. Expression and changes of galanin in neurons and microglia in the hippocampus after transient forebrain ischemia in gerbils. Brain research. vol 1023. issue 2. 2005-01-24. PMID:15374745. |
at this time point after ischemic insult, gal immunoreactivity was shown in microglia in the ca1 region because delayed neuronal death happened in the ca1 pyramidal cells. |
2005-01-24 |
2023-08-12 |
Not clear |
| Noriko Takahashi, Anton B Tonchev, Koji Koike, Kouichi Murakami, Kiyofumi Yamada, Tetsumori Yamashima, Masaki Inou. Expression of estrogen receptor-beta in the postischemic monkey hippocampus. Neuroscience letters. vol 369. issue 1. 2004-12-30. PMID:15380298. |
in contrast, erbeta immunoreactivity increased remarkably in the radiate and molecular layers of ca1, where it was present in astrocytes and microglia. |
2004-12-30 |
2023-08-12 |
monkey |
| In Koo Hwang, Ki-Yeon Yoo, Duk Soo Kim, Youn-Kab Jeong, Jong Dai Kim, Hyun-Kyung Shin, Soon Sung Lim, Ick-Dong Yoo, Tae-Cheon Kang, Dong-Woo Kim, Won-Kuk Moon, Moo Ho Wo. Neuroprotective effects of grape seed extract on neuronal injury by inhibiting DNA damage in the gerbil hippocampus after transient forebrain ischemia. Life sciences. vol 75. issue 16. 2004-09-30. PMID:15306166. |
in addition, we confirmed that astrocytes and microglia did not show significant activation in the ca1 region 4 days after ischemia-reperfusion, because many ca1 pyramidal cells were not damaged. |
2004-09-30 |
2023-08-12 |
Not clear |
| D-L Lei, J M Long, J Hengemihle, J O'Neill, K F Manaye, D K Ingram, P R Mouto. Effects of estrogen and raloxifene on neuroglia number and morphology in the hippocampus of aged female mice. Neuroscience. vol 121. issue 3. 2004-01-09. PMID:14568026. |
after 60 days, numbers of microglia and astrocytes were quantified in dentate gyrus and ca1 regions of the hippocampal formation using immunocytochemistry and design-based stereology. |
2004-01-09 |
2023-08-12 |
mouse |
| Hiroyuki Kato, Akira Takahashi, Yasuto Itoyam. Cell cycle protein expression in proliferating microglia and astrocytes following transient global cerebral ischemia in the rat. Brain research bulletin. vol 60. issue 3. 2003-08-08. PMID:12754083. |
proliferating cells in the ca1 region after ischemia consisted of microglia and much fewer astrocytes. |
2003-08-08 |
2023-08-12 |
rat |
| Peter R Mouton, Jeffrey M Long, De-Liang Lei, Victor Howard, Mathias Jucker, Michael E Calhoun, Donald K Ingra. Age and gender effects on microglia and astrocyte numbers in brains of mice. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426043. |
astrocytes and microglia were visualized using immunocytochemistry for glial fibrillary acidic protein (gfap) and complement receptor 3 (mac-1), respectively, and numbers of each cell type in dentate gyrus (dg) and ca1 regions were estimated using the optical fractionator method. |
2003-01-29 |
2023-08-12 |
mouse |
| Peter R Mouton, Jeffrey M Long, De-Liang Lei, Victor Howard, Mathias Jucker, Michael E Calhoun, Donald K Ingra. Age and gender effects on microglia and astrocyte numbers in brains of mice. Brain research. vol 956. issue 1. 2003-01-29. PMID:12426043. |
we also report that on average female b6 mice have 25-40% more astrocytes and microglia in dg and ca1 regions than age-matched male c57bl/6j mice. |
2003-01-29 |
2023-08-12 |
mouse |
| O T Wolf, V Dyakin, A Patel, C Vadasz, M J de Leon, B S McEwen, K Bulloc. Volumetric structural magnetic resonance imaging (MRI) of the rat hippocampus following kainic acid (KA) treatment. Brain research. vol 934. issue 2. 2002-08-07. PMID:11955471. |
the histological observations supported the mri data showing neuronal loss and neuronal degeneration in ca1 and ca3 of the hippocampus, which was accompanied by strong microglia activation. |
2002-08-07 |
2023-08-12 |
rat |