| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Paula Ortiz-Romero, Alejandro González-Simón, Gustavo Egea, Luis A Pérez-Jurado, Victoria Campuzan. Co-Treatment With Verapamil and Curcumin Attenuates the Behavioral Alterations Observed in Williams-Beuren Syndrome Mice by Regulation of MAPK Pathway and Microglia Overexpression. Frontiers in pharmacology. vol 12. 2021-08-21. PMID:34413771. |
cd mice showed an increased density of activated microglia in the motor cortex and ca1 hippocampal region, which was prevented by co-treatment. |
2021-08-21 |
2023-08-13 |
mouse |
| Nan Sun, Yong Mei, Zhengtao Hu, Wen Xing, Kun Lv, Nengwei Hu, Ting Zhang, Deguo Wan. Ghrelin attenuates depressive-like behavior, heart failure, and neuroinflammation in postmyocardial infarction rat model. European journal of pharmacology. vol 901. 2021-05-18. PMID:33848542. |
results showed that ghrelin substantially improved cardiac dysfunction, infarction size, and cardiac remodeling and modulated the release of inflammatory cytokines and the increase of iba-1 positive microglia and glial fibrillary acidic protein-positive astrocytes in the ca1 area of hippocampus. |
2021-05-18 |
2023-08-13 |
rat |
| Stephen Beesley, Thomas Sullenberger, Roshan Ailani, Cameron D'Orio, Mathew S Crockett, Sanjay S Kuma. d-Serine Intervention In The Medial Entorhinal Area Alters TLE-Related Pathology In CA1 Hippocampus Via The Temporoammonic Pathway. Neuroscience. vol 453. 2021-05-14. PMID:33197499. |
this intervention in the mea led to the rescue of hippocampal ca1 neurons that would have otherwise perished in the epileptic animals, and down regulation of the expression of astrocytes and microglia thereby mitigating the effects of neuroinflammation. |
2021-05-14 |
2023-08-13 |
rat |
| Daniele Lana, Filippo Ugolini, Daniele Nosi, Gary L Wenk, Maria Grazia Giovannin. The Emerging Role of the Interplay Among Astrocytes, Microglia, and Neurons in the Hippocampus in Health and Disease. Frontiers in aging neuroscience. vol 13. 2021-04-24. PMID:33889084. |
in the contiguous and interconnected regions of rat hippocampus, ca1 and ca3 stratum radiatum, astrocytes and microglia show a different, finely regulated, and region-specific reactivity, demonstrating that glia responses vary in a significant manner from area to area. |
2021-04-24 |
2023-08-13 |
rat |
| Alita Soch, Luba Sominsky, Simin Younesi, Simone N De Luca, Maneesha Gunasekara, Steven Bozinovski, Sarah J Spence. The role of microglia in the second and third postnatal weeks of life in rat hippocampal development and memory. Brain, behavior, and immunity. vol 88. 2021-04-06. PMID:32360602. |
this protracted effect on these key immune cells led to a small but significant increase in ca1 mature neuron numbers and a significant increase in astrocyte density in the subgranular dentate gyrus in adults that had their microglia ablated at p14. |
2021-04-06 |
2023-08-13 |
rat |
| Woosuk Kim, Kyu Ri Hahn, Hyo Young Jung, Hyun Jung Kwon, Sung Min Nam, Tae Hyeong Kim, Jong Whi Kim, Dae Young Yoo, Dae Won Kim, Jung Hoon Choi, Yeo Sung Yoon, In Koo Hwan. Cuprizone Affects Hypothermia-Induced Neuroprotection and Enhanced Neuroblast Differentiation in the Gerbil Hippocampus after Ischemia. Cells. vol 9. issue 6. 2021-03-18. PMID:32531881. |
however, cuprizone treatment decreased cell survival induced by hypothermic preconditioning after ischemia and increased the number of reactive microglia and astrocytes in ca1 as well as that of macrophages in the subcallosal zone. |
2021-03-18 |
2023-08-13 |
Not clear |
| Daniele Lana, Filippo Ugolini, Maria Grazia Giovannin. Space-Dependent Glia-Neuron Interplay in the Hippocampus of Transgenic Models of β-Amyloid Deposition. International journal of molecular sciences. vol 21. issue 24. 2021-03-15. PMID:33322419. |
differential crosstalk between astrocytes and microglia in ca1 and ca3 areas of the hippocampus can be responsible for the differential sensitivity of the two areas to insults. |
2021-03-15 |
2023-08-13 |
Not clear |
| Giorgi Lobzhanidze, Nadezhda Japaridze, Tamar Lordkipanidze, Fuad Rzayev, Derrick MacFabe, Mzia Zhvani. Behavioural and brain ultrastructural changes following the systemic administration of propionic acid in adolescent male rats. Further development of a rodent model of autism. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 80. issue 2. 2021-01-25. PMID:31997401. |
both transient and enduring ultrastructural alterations in synapses, astro- and microglia were detected in the ca1 hippocampal area. |
2021-01-25 |
2023-08-13 |
rat |
| Jae-Cheon Kim, Sun-Nyoung Hwang, Seong Yun Ki. Alteration of Gene Associated with Retinoid-interferon-induced Mortality-19-expressing Cell Types in the Mouse Hippocampus Following Pilocarpine-induced Status Epilepticus. Neuroscience. vol 425. 2020-12-15. PMID:31790668. |
neuronal death in the hippocampal ca1 area was prominently observed at 4 and 7 days after se, and astrocytes and microglia became progressively activated beginning at 1 day after se. |
2020-12-15 |
2023-08-13 |
mouse |
| Ji Yun Ahn, Bing Chun Yan, Joon Ha Park, Ji Hyeon Ahn, Dae Hwan Lee, In Hye Kim, Jeong-Hwi Cho, Bai Hui Chen, Jae-Chul Lee, Young Shin Cho, Myoung Chul Shin, Jun Hwi Cho, Seongkweon Hong, Moo-Ho Won, Sung Koo Ki. Novel antiepileptic drug lacosamide exerts neuroprotective effects by decreasing glial activation in the hippocampus of a gerbil model of ischemic stroke. Experimental and therapeutic medicine. vol 10. issue 6. 2020-10-01. PMID:26668588. |
furthermore, treatment with 25 mg/kg lacosamide markedly attenuated the activation of astrocytes and microglia in the ischemic ca1 region at 5 days post-ischemia. |
2020-10-01 |
2023-08-13 |
Not clear |
| Ting-Ting Qu, Jie-Xin Deng, Rui-Ling Li, Zhan-Jun Cui, Xiao-Qing Wang, Lai Wang, Jin-Bo Den. Stress injuries and autophagy in mouse hippocampus after chronic cold exposure. Neural regeneration research. vol 12. issue 3. 2020-10-01. PMID:28469659. |
results showed that oxidative stress-related c-fos and cyclooxygenase 2 expressions, map1lc3-labeled autophagic cells, iba1-labeled activated microglia, and interleukin-1β-positive pyramidal cells were increased in the hippocampal ca1 area. |
2020-10-01 |
2023-08-13 |
mouse |
| Hyun-Jin Tae, Il Jun Kang, Tae-Kyeong Lee, Jeong Hwi Cho, Jae-Chul Lee, Myoung Cheol Shin, Yoon Sung Kim, Jun Hwi Cho, Jong-Dai Kim, Ji Hyeon Ahn, Joon Ha Park, In-Shik Kim, Hyang-Ah Lee, Yang Hee Kim, Moo-Ho Won, Young Joo Le. Neuronal injury and tumor necrosis factor-alpha immunoreactivity in the rat hippocampus in the early period of asphyxia-induced cardiac arrest under normothermia. Neural regeneration research. vol 12. issue 12. 2020-09-30. PMID:29323039. |
iba-1 immunoreactive microglia in the ca1 region did not change until 1 day post-ca, and they were activated (enlarged cell bodies with short and thicken processes) in all layers 2 days post-ca. |
2020-09-30 |
2023-08-13 |
rat |
| Can Zhang, Nicole R Brandon, Kerryann Koper, Pei Tang, Yan Xu, Huanyu Do. Invasion of Peripheral Immune Cells into Brain Parenchyma after Cardiac Arrest and Resuscitation. Aging and disease. vol 9. issue 3. 2020-09-30. PMID:29896429. |
time profiles of hippocampal ca1 neuronal injuries correlated with the morphological changes of microglia activation. |
2020-09-30 |
2023-08-13 |
mouse |
| Filippo Ugolini, Daniele Lana, Pamela Nardiello, Daniele Nosi, Daniela Pantano, Fiorella Casamenti, Maria Grazia Giovannin. Different Patterns of Neurodegeneration and Glia Activation in CA1 and CA3 Hippocampal Regions of TgCRND8 Mice. Frontiers in aging neuroscience. vol 10. 2020-09-30. PMID:30483118. |
we found also common patterns of glia activation and neurodegenerative processes in ca1 and ca3 of tg 6m mice: significant increase of total and reactive microglia density in sp and sr, increased expression of tnfα, of inos, and il1β in astrocytes and increased density of neurons-astrocytes-microglia triads. |
2020-09-30 |
2023-08-13 |
mouse |
| Ai-Ling Xu, Guan-Yi Zheng, Hui-Ying Ye, Xiao-Dong Chen, Qiong Jian. Characterization of astrocytes and microglial cells in the hippocampal CA1 region after transient focal cerebral ischemia in rats treated with Ilexonin A. Neural regeneration research. vol 15. issue 1. 2020-09-30. PMID:31535655. |
however, the effects of ilexonin a on astrocytes and microglia in the infarct-free region of the hippocampal ca1 region remain unclear. |
2020-09-30 |
2023-08-13 |
rat |
| Julie C Savage, Marie-Kim St-Pierre, Chin Wai Hui, Marie-Eve Trembla. Microglial Ultrastructure in the Hippocampus of a Lipopolysaccharide-Induced Sickness Mouse Model. Frontiers in neuroscience. vol 13. 2020-09-30. PMID:31920505. |
microglial cell bodies and processes were investigated in the hippocampus ca1, a region responsible for learning and memory that is often impacted after peripheral lps administration. |
2020-09-30 |
2023-08-13 |
mouse |
| Ji Hyeon Ahn, Bich Na Shin, Joon Ha Park, Tae-Kyeong Lee, Young Eun Park, Jae-Chul Lee, Go Eun Yang, Myoung Cheol Shin, Jun Hwi Cho, Kyu Chang Lee, Moo-Ho Won, Hyeyoung Ki. Pre- and Post-Treatment with Novel Antiepileptic Drug Oxcarbazepine Exerts Neuroprotective Effect in the Hippocampus in a Gerbil Model of Transient Global Cerebral Ischemia. Brain sciences. vol 9. issue 10. 2020-09-28. PMID:31627311. |
we examined its neuroprotective effect in the cornu ammonis 1 subfield of the gerbil hippocampus at 5 days after transient ischemia by using cresyl violet staining, neuronal nuclei immunohistochemistry and fluoro-jade b histofluorescence staining for neuroprotection, and by using glial fibrillary protein and ionized calcium-binding adapter molecule 1 immunohistochemistry for reaction of astrocytes and microglia, respectively. |
2020-09-28 |
2023-08-13 |
Not clear |
| Ji Hyeon Ahn, Bich Na Shin, Joon Ha Park, Tae-Kyeong Lee, Young Eun Park, Jae-Chul Lee, Go Eun Yang, Myoung Cheol Shin, Jun Hwi Cho, Kyu Chang Lee, Moo-Ho Won, Hyeyoung Ki. Pre- and Post-Treatment with Novel Antiepileptic Drug Oxcarbazepine Exerts Neuroprotective Effect in the Hippocampus in a Gerbil Model of Transient Global Cerebral Ischemia. Brain sciences. vol 9. issue 10. 2020-09-28. PMID:31627311. |
in addition, pre- and post-treatment with oxcarbazepine (200 mg/kg) significantly ameliorated astrocytes and microglia activation in the ischemic cornu ammonis 1 subfield. |
2020-09-28 |
2023-08-13 |
Not clear |
| Gaurav Singhal, Julie Morgan, Magdalene C Jawahar, Frances Corrigan, Emily J Jaehne, Catherine Toben, Jim Manavis, Anthony J Hannan, Bernhard T Baun. Duration of Environmental Enrichment Determines Astrocyte Number and Cervical Lymph Node T Lymphocyte Proportions but Not the Microglial Number in Middle-Aged C57BL/6 Mice. Frontiers in cellular neuroscience. vol 14. 2020-09-28. PMID:32256319. |
ee, regardless of duration, caused an increase in microglia number within the dentate gyrus, ca1 and ca3 hippocampal regions, but only long-term ee increased astrocytes number within the dentate gyrus and ca3 hippocampal regions. |
2020-09-28 |
2023-08-13 |
mouse |
| Shi Yu, Hujing Zhang, Yue Hei, Xicai Yi, Andrius Baskys, Weiping Liu, Qianfa Lon. High mobility group box-1 (HMGB1) antagonist BoxA suppresses status epilepticus-induced neuroinflammatory responses associated with Toll-like receptor 2/4 down-regulation in rats. Brain research. vol 1717. 2020-09-24. PMID:30986405. |
in ex vivo experiments, post-se microglia cells were isolated from the hippocampal ca1 area and subjected to lipopolysaccharide (lps) stimulation followed by inflammatory cytokine il-1β and il-6 by qpcr and hmgb1, tlr2, tlr3 by western blotting. |
2020-09-24 |
2023-08-13 |
rat |