| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Andre R C Barreto-Vianna, Marcia B Aguila, Carlos A Mandarim-de-Lacerd. Beneficial effects of liraglutide (GLP1 analog) in the hippocampal inflammation. Metabolic brain disease. vol 32. issue 5. 2018-07-23. PMID:28681199. |
the hippocampal dentate gyrus and ca1 regions were analyzed (morphology and inflammation-related proteins in microglia and astrocyte by confocal microscopy). |
2018-07-23 |
2023-08-13 |
mouse |
| Yong Li, Jimok Ki. Distinct roles of neuronal and microglial CB2 cannabinoid receptors in the mouse hippocampus. Neuroscience. vol 363. 2018-06-08. PMID:28888955. |
elevation and disruption of cb2r expression in microglia in the ca1 area increased and decreased, respectively, contextual fear memory. |
2018-06-08 |
2023-08-13 |
mouse |
| Li-Na Sun, Xiao-Long Li, Fei Wang, Jun Zhang, Dan-Dan Wang, Li Yuan, Mei-Na Wu, Zhao-Jun Wang, Jin-Shun Q. High-intensity treadmill running impairs cognitive behavior and hippocampal synaptic plasticity of rats via activation of inflammatory response. Journal of neuroscience research. vol 95. issue 8. 2018-04-17. PMID:27918079. |
furthermore, accompanied by elevated levels of inflammatory factors il-1β, tnf-α, and inos, overactivation of microglia and astrocytes was also found in the ca1 region of hippocampus in the excessive exercise group, indicating an inflammatory response induced by hie. |
2018-04-17 |
2023-08-13 |
rat |
| Joon Ha Park, Jin-A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo-Ho Won, Choong-Hyun Le. Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28586018. |
transient cerebral ischemia induces albumin expression in microglia only in the ca1 region of the gerbil hippocampus. |
2018-03-26 |
2023-08-13 |
Not clear |
| Joon Ha Park, Jin-A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo-Ho Won, Choong-Hyun Le. Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28586018. |
albumin immunoreactivity was observed in microglia of the ca1 hippocampal region 2 days post‑ischemic insult, and it was significantly increased at 4 days following ischemia-reperfusion. |
2018-03-26 |
2023-08-13 |
Not clear |
| Joon Ha Park, Jin-A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo-Ho Won, Choong-Hyun Le. Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28586018. |
in addition, at 4 days post‑ischemic insult, albumin‑immunoreactive microglia were abundant in the stratum pyramidale of the ca1 region. |
2018-03-26 |
2023-08-13 |
Not clear |
| Joon Ha Park, Jin-A Park, Ji Hyeon Ahn, Yang Hee Kim, Il Jun Kang, Moo-Ho Won, Choong-Hyun Le. Transient cerebral ischemia induces albumin expression in microglia only in the CA1 region of the gerbil hippocampus. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28586018. |
the present results demonstrated that albumin was newly expressed post‑injury in microglia in the ca1 region, suggesting ischemia‑induced neuronal loss. |
2018-03-26 |
2023-08-13 |
Not clear |
| Ji Hyeon Ahn, Myoung Cheol Shin, Joon Ha Park, In Hye Kim, Jeong-Hwi Cho, Tae-Kyeong Lee, Jae-Chul Lee, Bai Hui Chen, Bich Na Shin, Hyun-Jin Tae, Jinseu Park, Soo Young Choi, Yun Lyul Lee, Dae Won Kim, Yang Hee Kim, Moo-Ho Won, Jun Hwi Ch. Effects of long‑term post‑ischemic treadmill exercise on gliosis in the aged gerbil hippocampus induced by transient cerebral ischemia. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28440411. |
glial fibrillary acidic protein‑immunoreactive astrocytes and ionized calcium binding adaptor molecule 1‑immunoreactive microglia were activated in the ca1 and polymorphic layer of the dentate gyrus of the group without treadmill exercise. |
2018-03-05 |
2023-08-13 |
Not clear |
| In Koo Hwang, Joon Ha Park, Tae-Kyeong Lee, Dae Won Kim, Ki-Yeon Yoo, Ji Hyeon Ahn, Yang Hee Kim, Jun Hwi Cho, Young-Myeong Kim, Moo-Ho Won, Seung Myung Moo. CD74-immunoreactive activated M1 microglia are shown late in the gerbil hippocampal CA1 region following transient cerebral ischemia. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28487994. |
cd74-immunoreactive activated m1 microglia are shown late in the gerbil hippocampal ca1 region following transient cerebral ischemia. |
2018-03-05 |
2023-08-13 |
Not clear |
| In Koo Hwang, Joon Ha Park, Tae-Kyeong Lee, Dae Won Kim, Ki-Yeon Yoo, Ji Hyeon Ahn, Yang Hee Kim, Jun Hwi Cho, Young-Myeong Kim, Moo-Ho Won, Seung Myung Moo. CD74-immunoreactive activated M1 microglia are shown late in the gerbil hippocampal CA1 region following transient cerebral ischemia. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28487994. |
in addition, ca1 regions were stained for cluster of differentiation (cd) 74, a marker for activated m1 microglia and a ligand for macrophage migration inhibitory factor in sham‑operated animals, no cd74 immunoreactivity was observed in the hippocampal ca1 region. |
2018-03-05 |
2023-08-13 |
Not clear |
| In Koo Hwang, Joon Ha Park, Tae-Kyeong Lee, Dae Won Kim, Ki-Yeon Yoo, Ji Hyeon Ahn, Yang Hee Kim, Jun Hwi Cho, Young-Myeong Kim, Moo-Ho Won, Seung Myung Moo. CD74-immunoreactive activated M1 microglia are shown late in the gerbil hippocampal CA1 region following transient cerebral ischemia. Molecular medicine reports. vol 15. issue 6. 2018-03-05. PMID:28487994. |
these results indicated that m1 microglia are activated late in the hippocampal ca1 region following ischemic stroke. |
2018-03-05 |
2023-08-13 |
Not clear |
| Jingrui Pan, Lei He, Xiangpen Li, Mei Li, Xiaoni Zhang, Jacob Venesky, Yi Li, Ying Pen. Activating Autophagy in Hippocampal Cells Alleviates the Morphine-Induced Memory Impairment. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26873855. |
here we showed that repeated morphine injection into c57bl/6 mice at a dose of 15 mg/kg per day for 7 days activated autophagic flux mainly in the hippocampi, especially in neurons of hippocampal ca1 region and microglia, with spatial memory impairment confirmed by morris water maze test. |
2018-02-07 |
2023-08-13 |
mouse |
| Jingrui Pan, Lei He, Xiangpen Li, Mei Li, Xiaoni Zhang, Jacob Venesky, Yi Li, Ying Pen. Activating Autophagy in Hippocampal Cells Alleviates the Morphine-Induced Memory Impairment. Molecular neurobiology. vol 54. issue 3. 2018-02-07. PMID:26873855. |
autophagy inhibition by 3-methyladenine obviously aggravates this morphine-induced memory impairment, accompanied with increased cell deaths in stratum pyramidale of hippocampal ca1, ca3, and dg regions and the activation of microglia to induce inflammation in hippocampus, such as upregulated expression of tnf-α, il-1β, il-6, and inos, as well as nf-κb' s activation, while morphine alone promoted microglial immunosuppression in hippocampus with autophagy activation which was also confirmed in primary microglia. |
2018-02-07 |
2023-08-13 |
mouse |
| Nicole D Schartz, Seth A Herr, Lauren Madsen, Sarah J Butts, Ceidy Torres, Loyda B Mendez, Amy L Brewste. Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus. Scientific reports. vol 6. 2018-01-18. PMID:27143585. |
recently, we reported a substantial decline in map2 that coincided with robust microglia accumulation in the ca1 hippocampal region after an episode of se. |
2018-01-18 |
2023-08-13 |
human |
| Nicole D Schartz, Seth A Herr, Lauren Madsen, Sarah J Butts, Ceidy Torres, Loyda B Mendez, Amy L Brewste. Spatiotemporal profile of Map2 and microglial changes in the hippocampal CA1 region following pilocarpine-induced status epilepticus. Scientific reports. vol 6. 2018-01-18. PMID:27143585. |
in contrast, maximal microglia accumulation occurred in the ca1 area at 14 days post-se. |
2018-01-18 |
2023-08-13 |
human |
| Andiara E Freitas, Javier Egea, Izaskun Buendia, Vanessa Gómez-Rangel, Esther Parada, Elisa Navarro, Ana Isabel Casas, Aneta Wojnicz, José Avendaño Ortiz, Antonio Cuadrado, Ana Ruiz-Nuño, Ana Lúcia S Rodrigues, Manuela G Lope. Agmatine, by Improving Neuroplasticity Markers and Inducing Nrf2, Prevents Corticosterone-Induced Depressive-Like Behavior in Mice. Molecular neurobiology. vol 53. issue 5. 2017-12-25. PMID:25966970. |
agmatine also abolished the corticosterone-induced changes in the morphology of astrocytes and microglia in ca1 region of hippocampus. |
2017-12-25 |
2023-08-13 |
mouse |
| Joon Ha Park, Chan Woo Park, Ji Hyeon Ahn, Soo Young Choi, Myoung Cheol Shin, Jun Hwi Cho, Tae-Kyeong Lee, In Hye Kim, Jeong Hwi Cho, Jae-Chul Lee, Yang Hee Kim, Young-Myeong Kim, Jong-Dai Kim, Hyun-Jin Tae, Bich Na Shin, Eun Joo Bae, Bai Hui Chen, Moo-Ho Won, Il Jun Kan. Neuroprotection and reduced gliosis by pre- and post-treatments of hydroquinone in a gerbil model of transient cerebral ischemia. Chemico-biological interactions. vol 278. 2017-12-12. PMID:28137511. |
in addition, pre- and post-treatments with 100 mg/kg of hq significantly attenuated activations of astrocytes and microglia in the ischemic ca1 region compared to the vehicle-treated-ischemia-operated group. |
2017-12-12 |
2023-08-13 |
Not clear |
| Qinwen Mao, Dongyang Wang, Yanqing Li, Missia Kohler, Jayson Wilson, Zachary Parton, Bella Shmaltsuyeva, Demirkan Gursel, Rosa Rademakers, Sandra Weintraub, Marek-Marsel Mesulam, Haibin Xia, Eileen H Bigi. Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration. Journal of neuropathology and experimental neurology. vol 76. issue 11. 2017-10-27. PMID:29044416. |
in the hippocampus, grn immunopositivity in the ca1 and ca2 regions showed disease-specific changes in both neurons and microglia. |
2017-10-27 |
2023-08-13 |
Not clear |
| Qinwen Mao, Dongyang Wang, Yanqing Li, Missia Kohler, Jayson Wilson, Zachary Parton, Bella Shmaltsuyeva, Demirkan Gursel, Rosa Rademakers, Sandra Weintraub, Marek-Marsel Mesulam, Haibin Xia, Eileen H Bigi. Disease and Region Specificity of Granulin Immunopositivities in Alzheimer Disease and Frontotemporal Lobar Degeneration. Journal of neuropathology and experimental neurology. vol 76. issue 11. 2017-10-27. PMID:29044416. |
most interestingly, in ftld-tdp type a with grn mutations, there is a 60% decrease in the density of grn-positive microglia in the hippocampal ca1, suggesting that haploinsufficiency of the grn mutations also extends to pgrn expression in microglia. |
2017-10-27 |
2023-08-13 |
Not clear |
| Masaaki Iwata, Hisahito Ishida, Koichi Kaneko, Yukihiko Shirayam. Learned helplessness activates hippocampal microglia in rats: A potential target for the antidepressant imipramine. Pharmacology, biochemistry, and behavior. vol 150-151. 2017-08-31. PMID:27769904. |
we noted significantly increased numbers of activated microglia in the granule cell layer, hilus, ca1, and ca3 regions of the hippocampi of lh rats. |
2017-08-31 |
2023-08-13 |
rat |