| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Kangning Xu, Yufen Zhang, Yan Wang, Peng Ling, Xin Xie, Chenyao Jiang, Zhizhen Zhang, Xiao-Yuan Lia. Ginseng Rb fraction protects glia, neurons and cognitive function in a rat model of neurodegeneration. PloS one. vol 9. issue 6. 2015-10-28. PMID:24971630. |
ka injection produced significant acute hippocampal injuries, including gad67-positive gabaergic interneuron loss in ca1, paralbumin (pv)-positive gabaergic interneuron loss, pyramidal neuron degeneration and astrocyte damage accompanied with reactive microglia in both ca1 and ca3 regions of the hippocampus. |
2015-10-28 |
2023-08-13 |
rat |
| Jae-Chul Lee, Bai Hui Chen, Jeong-Hwi Cho, In Hye Kim, Ji Hyeon Ahn, Joon Ha Park, Hyun-Jin Tae, Geum-Sil Cho, Bing Chun Yan, Dae Won Kim, In Koo Hwang, Jinseu Park, Yun Lyul Lee, Soo Young Choi, Moo-Ho Wo. Changes in the expression of DNA-binding/differentiation protein inhibitors in neurons and glial cells of the gerbil hippocampus following transient global cerebral ischemia. Molecular medicine reports. vol 11. issue 4. 2015-09-16. PMID:25503067. |
five days following i-r, strong id4 immunoreactivity was detected in non‑pyramidal cells, which were identified as microglia, and not astrocytes, in the ischemic ca1 region. |
2015-09-16 |
2023-08-13 |
Not clear |
| Hyo Geun Kim, Ji-Young Kim, Wei-Wan Whang, Myung Sook O. Neuroprotective effect of Chunghyuldan from amyloid beta oligomer induced neuroinflammation in vitro and in vivo. Canadian journal of physiology and pharmacology. vol 92. issue 6. 2015-08-31. PMID:24820962. |
in an in-vivo ad model, administration of chd (50 mg·(kg body mass)(-1), for 5 days, per oral) inhibited the activation of astrocytes and microglia in the dentate gyrus and neuronal damage in the ca1 of the ipsilateral hippocampus. |
2015-08-31 |
2023-08-13 |
rat |
| Yu-Wen Hung, Shao-Wen Hung, Yi-Chen Wu, Lin-King Wong, Ming-Tsong Lai, Yang-Hsin Shih, Tzong-Shyuan Lee, Yung-Yang Li. Soluble epoxide hydrolase activity regulates inflammatory responses and seizure generation in two mouse models of temporal lobe epilepsy. Brain, behavior, and immunity. vol 43. 2015-08-07. PMID:25135858. |
in the hippocampus of wt mice, seh was mainly expressed in astrocytes (gfap(+)), neurons (neun(+)) and scattered microglia (iba-1(+)) in the regions of ca1, ca3 and dentate gyrus. |
2015-08-07 |
2023-08-13 |
mouse |
| Qian-Yan Wang, Peng Sun, Qing Zhang, Shang-Long Ya. Minocycline attenuates microglial response and reduces neuronal death after cardiac arrest and cardiopulmonary resuscitation in mice. Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban. vol 35. issue 2. 2015-08-06. PMID:25877356. |
the results showed that the neuronal death was aggravated, most microglia were activated and tnf-α levels were enhanced in the hippocampus ca1 region of mice subjected to ca/cpr as compared with those in the sham-operated group (p<0.05). |
2015-08-06 |
2023-08-13 |
mouse |
| Carlos Santos-Filho, Camila M de Lima, César A R Fôro, Marcus A de Oliveira, Nara G M Magalhães, Cristovam Guerreiro-Diniz, Daniel G Diniz, Pedro F da C Vasconcelos, Cristovam W P Dini. Visuospatial learning and memory in the Cebus apella and microglial morphology in the molecular layer of the dentate gyrus and CA1 lacunosum molecular layer. Journal of chemical neuroanatomy. vol 61-62. 2015-07-31. PMID:25462387. |
we investigated whether the morphology of microglia in the molecular layer of the dentate gyrus (dg-mol) or in the lacunosum molecular layer of ca1 (ca1-lmol) was correlated with spatial learning and memory in the capuchin monkey (cebus apella). |
2015-07-31 |
2023-08-13 |
monkey |
| Seok Joon Won, Ji-Eun Kim, Giordano Fabricio Cittolin-Santos, Raymond A Swanso. Assessment at the single-cell level identifies neuronal glutathione depletion as both a cause and effect of ischemia-reperfusion oxidative stress. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 35. issue 18. 2015-07-24. PMID:25948264. |
at 3 d following ischemia, gsh content in reactive astrocytes and microglia was increased in the hippocampal ca1 relative to surviving neurons. |
2015-07-24 |
2023-08-13 |
mouse |
| Kyoung Hoon Jeong, Un Ju Jung, Sang Ryong Ki. Naringin Attenuates Autophagic Stress and Neuroinflammation in Kainic Acid-Treated Hippocampus In Vivo. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-06-30. PMID:26124853. |
moreover, naringin treatment protected hippocampal ca1 neurons in the ka-treated hippocampus, ameliorated ka-induced autophagic stress, confirmed by the expression of microtubule-associated protein light chain 3 (lc3), and attenuated an increase in tumor necrosis factor-α (tnfα) in activated microglia. |
2015-06-30 |
2023-08-13 |
mouse |
| Yuan Le, Shuli Liu, Mingchao Peng, Chang Tan, Qin Liao, Kaiming Duan, Wen Ouyang, Jianbin Ton. Aging differentially affects the loss of neuronal dendritic spine, neuroinflammation and memory impairment at rats after surgery. PloS one. vol 9. issue 9. 2015-05-28. PMID:25198176. |
we found that (1) in young adult rats, the memory was not significantly affected (p>0.05) 1d, 3d and 7d after partial hepatectomy, but was significantly impaired (p<0.001) in aged rats 1d and 3d post-surgery; (2) in young adult rats, the surgery did not significantly affect the densities of dendritic spines of neurons at ca1, dentate gyrus (dg) and cingulate cortex (p>0.05, respectively) 1d and 3d post-surgery, but the spine densities at ca1 and dg of aged rats were significant reduced 1d and 3d post-surgery (p<0.001, respectively), however this didn't happen at cingulate cortex (p>0.05); (3) in young adult rats, surgery didn't affect the activation of microglia and levels of tnf-α and il-1β at hippocampus (p>0.05), but significantly activated microglia and increased levels of tnf-α and il-1β at hippocampus of aged rats (p<0.05). |
2015-05-28 |
2023-08-13 |
rat |
| Bing Chun Yan, Joon Ha Park, Ji Hyeon Ahn, In Hye Kim, Ok Kyu Park, Jae-Chul Lee, Ki-Yeon Yoo, Jung Hoon Choi, Choong Hyun Lee, In Koo Hwang, Jeong Ho Park, Song Her, Jin Su Kim, Hyung-Cheul Shin, Jun Hwi Cho, Young-Myeong Kim, Seung-Hae Kwon, Moo-Ho Wo. Neuroprotection of posttreatment with risperidone, an atypical antipsychotic drug, in rat and gerbil models of ischemic stroke and the maintenance of antioxidants in a gerbil model of ischemic stroke. Journal of neuroscience research. vol 92. issue 6. 2014-11-25. PMID:24481585. |
in addition, treatment with risperidone markedly attenuated the activation of microglia in the gerbil ca1. |
2014-11-25 |
2023-08-12 |
rat |
| Rengfei Shi, Shunli Wang, Xiang Qi, Si Chen, Peijie Chen, Quanguang Zhan. Lose dose genistein inhibits glucocorticoid receptor and ischemic brain injury in female rats. Neurochemistry international. vol 65. 2014-10-20. PMID:24334056. |
in addition, our results indicated that genistein markedly prevented the excessive activation of microglia in ca1 sector. |
2014-10-20 |
2023-08-12 |
rat |
| Jae-Chul Lee, Ji Hyeon Ahn, In Hye Kim, Joon Ha Park, Bing Chun Yan, Geum-Sil Cho, Taek Geun Ohk, Chan Woo Park, Jun Hwi Cho, Young-Myeong Kim, Hui Young Lee, Moo-Ho Wo. Transient ischemia-induced change of CCR7 immunoreactivity in neurons and its new expression in astrocytes in the gerbil hippocampus. Journal of the neurological sciences. vol 336. issue 1-2. 2014-09-29. PMID:24262993. |
in addition, ccr7 immunoreactivity was newly expressed in astrocytes, not microglia, in the ischemic ca1 region from 5 days post-ischemia. |
2014-09-29 |
2023-08-12 |
Not clear |
| Sung Min Nam, Yo Na Kim, Dae Young Yoo, Sun Shin Yi, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Hypothyroidism affects astrocyte and microglial morphology in type 2 diabetes. Neural regeneration research. vol 8. issue 26. 2014-09-10. PMID:25206556. |
glial fibrillary acidic protein immunoreactive astrocytes and ionized calcium-binding adapter molecule 1 (iba-1)-immunoreactive microglia in the zucker lean control and zucker diabetic fatty group were diffusely detected in the hippocampal ca1 region and dentate gyrus. |
2014-09-10 |
2023-08-13 |
rat |
| Sung Min Nam, Yo Na Kim, Dae Young Yoo, Sun Shin Yi, Jung Hoon Choi, In Koo Hwang, Je Kyung Seong, Yeo Sung Yoo. Hypothyroidism affects astrocyte and microglial morphology in type 2 diabetes. Neural regeneration research. vol 8. issue 26. 2014-09-10. PMID:25206556. |
however, in the methimazole-treated zucker lean control and zucker diabetic fatty groups, the processes of glial fibrillary acidic protein tive astrocytes and iba-1 immunoreactive microglia, were significantly decreased in both the ca1 region and dentate gyrus compared to that in the vehicle-treated zucker lean control and zucker diabetic fatty groups. |
2014-09-10 |
2023-08-13 |
rat |
| Joon Ha Park, Choong Hyun Lee, In Hye Kim, Ji Hyeon Ahn, Jeong-Hwi Cho, Bing Chun Yan, Jae-Chul Lee, Tae Hun Lee, Jeong Yeol Seo, Jun Hwi Cho, Moo-Ho Won, Il-Jun Kan. Time-course changes in immunoreactivities of glucokinase and glucokinase regulatory protein in the gerbil hippocampus following transient cerebral ischemia. Neurochemical research. vol 38. issue 12. 2014-07-21. PMID:24146201. |
five days after i-r, gk and gkrp immunoreactivities were hardly detected in the ca1, not ca2/3, pyramidal neurons; however, at this point in time, gk and gkrp immunoreactivities were newly expressed in astrocytes, not microglia, in the ischemic ca1. |
2014-07-21 |
2023-08-12 |
Not clear |
| J J Rodríguez, H N Noristani, T Hilditch, M Olabarria, C Y Yeh, J Witton, A Verkhratsk. Increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the CA1 subfield of the hippocampus in the triple transgenic model of Alzheimer's disease. Neuroscience letters. vol 552. 2014-05-15. PMID:23827221. |
increased densities of resting and activated microglia in the dentate gyrus follow senile plaque formation in the ca1 subfield of the hippocampus in the triple transgenic model of alzheimer's disease. |
2014-05-15 |
2023-08-12 |
mouse |
| Gergely Silasi, Frederick Colbourn. Unilateral brain hypothermia as a method to examine efficacy and mechanisms of neuroprotection against global ischemia. Therapeutic hypothermia and temperature management. vol 1. issue 2. 2014-04-11. PMID:24716998. |
hypothermia significantly lessened ca1 injury and microglia activation on the right side at 1 and 4 week survival times. |
2014-04-11 |
2023-08-13 |
rat |
| In Hye Kim, Bing Chun Yan, Joon Ha Park, Go Heum Yeun, Yongbae Yim, Ji Hyeon Ahn, Jae-Chul Lee, In Koo Hwang, Jun Hwi Cho, Young-Myeong Kim, Yun Lyul Lee, Jeong Ho Park, Moo-Ho Wo. Neuroprotection of a novel synthetic caffeic acid-syringic acid hybrid compound against experimentally induced transient cerebral ischemic damage. Planta medica. vol 79. issue 5. 2014-01-14. PMID:23412993. |
we also observed changes in glial cells (astrocytes and microglia) in the ischemic hippocampal ca1 region in all the groups. |
2014-01-14 |
2023-08-12 |
Not clear |
| Hideaki Suzuki, Akira Sumiyoshi, Yasuyuki Taki, Yasuharu Matsumoto, Yoshihiro Fukumoto, Ryuta Kawashima, Hiroaki Shimokaw. Voxel-based morphometry and histological analysis for evaluating hippocampal damage in a rat model of cardiopulmonary resuscitation. NeuroImage. vol 77. 2013-12-23. PMID:23558096. |
brains were fixed, and the number of neurons and microglia in ca1 were counted. |
2013-12-23 |
2023-08-12 |
rat |
| Hideaki Suzuki, Akira Sumiyoshi, Yasuyuki Taki, Yasuharu Matsumoto, Yoshihiro Fukumoto, Ryuta Kawashima, Hiroaki Shimokaw. Voxel-based morphometry and histological analysis for evaluating hippocampal damage in a rat model of cardiopulmonary resuscitation. NeuroImage. vol 77. 2013-12-23. PMID:23558096. |
gmc values were positively correlated with the number of neurons and tended to be negatively correlated with the number of microglia in ca1 of cpr rats. |
2013-12-23 |
2023-08-12 |
rat |