All Relations between microglial cell and hippocampus

Reference Sentence Publish Date Extraction Date Species
Aarti Nagayach, Rakesh Bhaskar, Ishan Patr. Microglia activation and inflammation in hippocampus attenuates memory and mood functions during experimentally induced diabetes in rat. Journal of chemical neuroanatomy vol 125 issue 2022 36089179 conclusively, present data not only comprehends the microglia, macrophage physiology and related immune response in functionally different hippocampal regions associated cognitive and behavioural deficits, but also offers a suggestive region-specific cellular mechanism pathway for developing an imminent therapeutic approach during particular diabetes deficits. 2022-09-24 2022-09-29 Not clear
Bao-Dong He, Chang-Mei Liu, Zhao-Qian Ten. A Mouse Model of Neurodegeneration Induced by Blade Penetrating Stab Wound to the Hippocampus. Biology vol 11 issue 9 2022 36138848 mice with a hippocampal blade stab injury (hbsi) displayed the activation of microglia and astrocytes, inflammation, neuronal apoptosis, and deficits in spatial learning and memory. 2022-09-23 2022-09-29 Not clear
Barbara B Shih, Sarah M Brown, Jack Barrington, Lucas Lefevre, Neil A Mabbott, Josef Priller, Gerard Thompson, Alistair B Lawrence, Barry W McCol. Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia. Glia vol issue 2022 36120803 we isolated pig hippocampal tissue and microglia from frontal cortex, hippocampus, and cerebellum, as well as alveolar macrophages from the lungs and conducted rna-sequencing (rnaseq). 2022-09-19 2022-09-29 Not clear
Barbara B Shih, Sarah M Brown, Jack Barrington, Lucas Lefevre, Neil A Mabbott, Josef Priller, Gerard Thompson, Alistair B Lawrence, Barry W McCol. Defining the pig microglial transcriptome reveals its core signature, regional heterogeneity, and similarity with human and rodent microglia. Glia vol issue 2022 36120803 by comparing the transcriptomic profiles between microglia, macrophages, and hippocampal tissue, we derived a set of 239 highly enriched genes defining the porcine core microglial signature. 2022-09-19 2022-09-29 Not clear
Yuhua Ji, Zixin Chen, Ziqi Cen, Yuting Ye, Shuyuan Li, Xiaoshuang Lu, Qian Shao, Donghao Wang, Juling Ji, Qiuhong J. A comprehensive mouse brain acetylome-the cellular-specific distribution of acetylated brain proteins. Frontiers in cellular neuroscience vol 16 issue 2022 36111245 further immunofluorescence staining illustrated that acetylated proteins were mainly distributed in the nuclei of cortex neurons and axons of hippocampal neurons, sparsely distributed in the nuclei of microglia and astrocytes, and the lack of distribution in both cytoplasm and nuclei of cerebrovascular endothelial cells. 2022-09-16 2022-09-20 Not clear
Chenlu Xu, Jia Zhang, Qinfeng Zhou, Juling Wang, Chenyang Liu, Yu Tian, Danni Huang, Huaizhuang Ye, Yongtang Ji. Exposure to a real traffic environment impairs brain cognition in aged mice. Environmental research vol issue 2022 36113572 trap exposure increased the number of activated microglia in the hippocampal dg, ca1, ca3 regions and dorsolateral prefrontal cortex (dpfc). 2022-09-16 2022-09-29 Not clear
Xiaolin Zhong, Zuyao Chen, Yajuan Wang, Mingli Mao, Yingcheng Deng, Mengmeng Shi, Yang Xu, Ling Chen, Wenyu Ca. JQ1 attenuates neuroinflammation by inhibiting the inflammasome-dependent canonical pyroptosis pathway in SAE. Brain research bulletin vol issue 2022 36100190 interestingly, we also found that jq1 selectively suppressed the activation of hippocampal microglia in sae mice. 2022-09-13 2022-09-20 Not clear
Alexander Beletskiy, Ekaterina Positselskaya, Aliya Kh Vinarskaya, Yulia S Spivak, Yulia V Dobryakova, Iliya Tyulenev, Vladimir A Markevich, Alexey P Bolshako. Detailed Analysis of Dorsal-Ventral Gradients of Gene Expression in the Hippocampus of Adult Rats. International journal of molecular sciences vol 23 issue 17 2022 36077346 furthermore, analysis of differential expressions of genes specific for astrocytes, microglia, oligodendrocytes, and vascular cells suggests that non-neuronal cells may also differ in the characteristics between hippocampal parts. 2022-09-09 2022-09-14 Not clear
Lauren McClure Yauch, Kathleen Ennis-Czerniak, William H Frey Ii, Ivan Tkac, Raghavendra B Ra. Intranasal Insulin Attenuates the Long-term Adverse Effects of Neonatal Hyperglycemia on the Hippocampus in Rats. Developmental neuroscience vol issue 2022 36041414 compared with the stz group, phosphocreatine and phosphocreatine/creatine ratio were higher, and microglia in the hippocampal subareas fewer in the stz + ins group (p < 0.05 for all). 2022-08-30 2022-09-06 Not clear
Tingting Zhou, Suli He, Xin Ye, Zhaolan Wei, Jian Wan, Hongmao Zhang, Shumao Din. Exposure to dibutyl phthalate adsorbed to multi-walled carbon nanotubes causes neurotoxicity in mice by inducing the release of BDNF. The Science of the total environment vol issue 2022 36041608 staining of hippocampal sections of mouse brain tissue showed that, in the ca1, ca2, and dg areas, the number of neurons decreased, the nucleus was pyknotic, the cell body was atrophied, and levels of the microglia marker iba-1 increased. 2022-08-30 2022-09-06 Not clear
Yanjun Lu, Lu Tan, Jiazhao Xie, Liming Cheng, Xiong Wan. Distinct microglia alternative splicing in Alzheimer's disease. Aging vol 14 issue undefined 2022 36006403 we described as events in the hippocampal microglia sorted by cd45 and cd11b from a\xce\xb2 precursor protein (app) and non-transgenic (ntg) mice. 2022-08-25 2022-08-29 Not clear
Zhiqian Yu, Mai Sakai, Hotaka Fukushima, Chiaki Ono, Yoshie Kikuchi, Ryuta Koyama, Ko Matsui, Tomoyuki Furuyashiki, Satoshi Kida, Hiroaki Tomit. Contextual fear conditioning regulates synapse-related gene transcription in mouse microglia. Brain research bulletin vol issue 2022 35987296 furthermore, in the hippocampal microglia, we found that the expression of neurotransmitter release regulators, \xce\xb3-aminobutyric acid (gaba) receptor gabrb3 and synapsin 1/2, increased under fear memory consolidation and restored (decreased) after extinction. 2022-08-20 2022-08-22 Not clear
Gang Li, Jun Zhou, Jicheng Wei, Bin Li. Dexmedetomidine Ameliorated Cognitive Dysfunction Induced by Intestinal Ischemia Reperfusion in Mice with Possible Relation to the Anti-inflammatory Effect Through the Locus Coeruleus Norepinephrine System. Neurochemical research vol issue 2022 35945306 immunofluorescence, immunohistochemistry, and hematoxylin and eosin staining were used to evaluate the expression of tyrosine hydroxylase (th) in the locus coeruleus, hippocampal microglia, and intestinal injury. 2022-08-09 2022-08-15 Not clear
Kata T\\xc3\\xb3th, Tam\\xc3\\xa1s Oroszi, Eddy A van der Zee, Csaba Nyakas, Regien G Schoemake. Sex dimorphism in isoproterenol-induced cardiac damage associated neuroinflammation and behavior in old rats. Frontiers in aging neuroscience vol 14 issue 2022 35936761 baseline hippocampal microglia activity was lower in females, while iso induced neuroinflammation in both sexes, hippocampal brain-derived neurotrophic factor expression appeared lower in females, without effects of iso. 2022-08-08 2022-08-15 Not clear
Xiao Fan Xu, Meng Meng Shi, Ming Ying Luo, Dan Dan Liu, Dong Ming Guo, Chen Ling, Xiao Lin Zhong, Yang Xu, Wen Yu Ca. Targeting PERK mediated endoplasmic reticulum stress attenuates neuroinflammation and alleviates lipopolysaccharide-induced depressive-like behavior in male mice. International immunopharmacology vol 111 issue 2022 35940075 importantly, we found that perkinhibitorisrib reducedthe proinflammatory responsesof microglia in the context of acute lps-induced brain inflammation, and subsequent the preserved hippocampal neurogenesis, and improvement in depression-like behavioroutcomes following lps challenges.it was also worth mentioning thatisrib treatmentreduced the peripheral pro-inflammatory cytokines includingil-1\xce\xb2, il-6 and il-18. 2022-08-08 2022-08-15 Not clear
Ryosuke Kamei, Shinji Urata, Hisato Maruoka, Shigeo Okab. In vivo Chronic Two-Photon Imaging of Microglia in the Mouse Hippocampus. Journal of visualized experiments : JoVE vol issue 185 2022 35876553 the unique functions of the hippocampal neural network in learning and memory may be associated with the active roles of microglia in synapse remodeling. 2022-07-25 2022-08-08 Not clear
Ryosuke Kamei, Shinji Urata, Hisato Maruoka, Shigeo Okab. In vivo Chronic Two-Photon Imaging of Microglia in the Mouse Hippocampus. Journal of visualized experiments : JoVE vol issue 185 2022 35876553 however, inflammatory responses induced by surgical procedures have been problematic in the two-photon microscopic analysis of hippocampal microglia. 2022-07-25 2022-08-08 Not clear
Ryosuke Kamei, Shinji Urata, Hisato Maruoka, Shigeo Okab. In vivo Chronic Two-Photon Imaging of Microglia in the Mouse Hippocampus. Journal of visualized experiments : JoVE vol issue 185 2022 35876553 the transient inflammatory response of hippocampal microglia may prevent imaging immediately after surgery, but the microglia restore their quiescent morphology within a few weeks. 2022-07-25 2022-08-08 Not clear
Zi-Rong Li, De-Guo Liu, Sheng Xie, Yu-Hong Wang, Yuan-Shan Han, Chun-Yan Li, Man-Shu Zou, Hai-Xing Jian. Sleep deprivation leads to further impairment of hippocampal synaptic plasticity by suppressing melatonin secretion in the pineal gland of chronically unpredictable stress rats. European journal of pharmacology vol issue 2022 35878808 in addition to improving depressive-like behaviors, sleep deprivation also upregulates the expression of caspase-specific cysteine protein 3 (caspase 3) in the pineal glial cells of chronic mild rats, as well as in hippocampal microglia. 2022-07-25 2022-08-08 Not clear
Marcella Massimini, Benedetta Bachetti, Elena Dalle Vedove, Alessia Benvenga, Francesco Di Pierro, Nicola Bernab\\xc3\\xb. A Set of Dysregulated Target Genes to Reduce Neuroinflammation at Molecular Level. International journal of molecular sciences vol 23 issue 13 2022 35806178 considering the important role of microglia in neurodegeneration, a murine co-culture of hippocampal cells and inflamed microglia cells was set up. 2022-07-09 2022-07-11 Not clear
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