All Relations between microglial cell and hippocampus

Publication Sentence Publish Date Extraction Date Species
Isaac Vargas-Rodríguez, Luis Antonio Reyes-Castro, Gustavo Pacheco-López, Consuelo Lomas-Soria, Elena Zambrano, Araceli Díaz-Ruíz, Sofía Diaz-Cintr. POSTNATAL EXPOSURE TO LIPOPOLYSACCHARIDE COMBINED WITH HIGH-FAT DIET CONSUMPTION INDUCES IMMUNE TOLERANCE WITHOUT PREVENTION IN SPATIAL WORKING MEMORY IMPAIRMENT. Behavioural brain research. 2022-02-05. PMID:35120930. hfd exposure has a pro-inflammatory effect associated with microglial cell modifications in the hippocampus, a region involved in the working memory process. 2022-02-05 2023-08-13 mouse
Y Lakshmisha Rao, B Ganaraja, B V Murlimanju, Teresa Joy, Ashwin Krishnamurthy, Amit Agrawa. Hippocampus and its involvement in Alzheimer's disease: a review. 3 Biotech. vol 12. issue 2. 2022-02-04. PMID:35116217. the microglia in the hippocampal region are more immunologically active than the other regions of the brain. 2022-02-04 2023-08-13 Not clear
Zongyang Li, Yuan Zhang, Xiangbao Meng, Min Li, Weiwei Cao, Junshan Yang, Xudong Xu, Wenlan Liu, Weiping Li, Qian Cai, Sicen Wang, Guoxu Ma, Zhiheng Liu, Guodong Huan. A novel DPP-4 inhibitor Gramcyclin A attenuates cognitive deficits in APP/PS1/tau triple transgenic mice via enhancing brain GLP-1-dependent glucose uptake. Phytotherapy research : PTR. 2022-01-28. PMID:35088915. treatment with gramcyclin a remarkedly decreased the level of microglia and suppressed neuroinflammation in the hippocampus of app/ps1/tau mice. 2022-01-28 2023-08-13 mouse
Ping Zheng, Qingke Bai, Jiugeng Feng, Bing Zhao, Jian Duan, Lin Zhao, Ning Liu, Dabin Ren, Shufeng Zou, Wei Che. Neonatal microglia and proteinase inhibitors-treated adult microglia improve traumatic brain injury in rats by resolving the neuroinflammation. Bioengineering & translational medicine. vol 7. issue 1. 2022-01-26. PMID:35079627. the injection of neonatal microglia inhibited cell apoptosis, reduced astrocytosis and microgliosis, decreased the level of chemokines and cytokines in cortex and ipsilateral hippocampus, and improved cognitive function of tbi rat model. 2022-01-26 2023-08-13 rat
Tik Muk, Allan Stensballe, Oksana Dmytriyeva, Anders Brunse, Ping-Ping Jiang, Thomas Thymann, Per Torp Sangild, Stanislava Pankratov. Differential Brain and Cerebrospinal Fluid Proteomic Responses to Acute Prenatal Endotoxin Exposure. Molecular neurobiology. 2022-01-22. PMID:35064541. microglia, but not astrocytes, were activated by lps at p5 in the hippocampus but not in other brain regions. 2022-01-22 2023-08-13 Not clear
Dahae Lee, Hyejung Jo, Cheolhyeon Go, Yoojin Jang, Naghyung Chu, Suhyun Bae, Dongmin Kang, Yejin Kim, Jae Seung Kan. The Roles of IL-22 and Its Receptor in the Regulation of Inflammatory Responses in the Brain. International journal of molecular sciences. vol 23. issue 2. 2022-01-21. PMID:35054942. here, we used rt-pcr, western blotting, flow cytometry, immunohistochemical, and microarray analyses to examine the role of il-22 and expression of il-22rα in the brain, using the microglial cell line, hippocampal neuronal cell line, and inflamed mouse brain tissue. 2022-01-21 2023-08-13 mouse
Bohyun Yang, Jae-Sang Ryu, Chan Rim, Jung U Shin, Min-Soo Kwo. Possible role of arginase 1 positive microglia on depressive/anxiety-like behaviors in atopic dermatitis mouse model. Archives of pharmacal research. 2022-01-21. PMID:35060088. in addition, ad mice showed microglia with a shortened branch of de-ramified form and astrocytes with longer processes and decreased branching in the hippocampus, especially in the dentate gyrus (dg). 2022-01-21 2023-08-13 mouse
Shane M O'Neil, Emma E Hans, Starr Jiang, Lynde M Wangler, Jonathan P Godbou. Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation. Glia. 2022-01-21. PMID:35061297. using single-cell rna-sequencing, we confirmed hippocampal microglia of aged mice (18 m.o.) 2022-01-21 2023-08-13 mouse
Shane M O'Neil, Emma E Hans, Starr Jiang, Lynde M Wangler, Jonathan P Godbou. Astrocyte immunosenescence and deficits in interleukin 10 signaling in the aged brain disrupt the regulation of microglia following innate immune activation. Glia. 2022-01-21. PMID:35061297. moreover, microglia in the aged hippocampus failed to turn over during the resolving phase of neuroinflammation. 2022-01-21 2023-08-13 mouse
Christiane Kruse Fæste, Anita Solhaug, Marion Gaborit, Florian Pierre, Dominique Massott. Neurotoxic Potential of Deoxynivalenol in Murine Brain Cell Lines and Primary Hippocampal Cultures. Toxins. vol 14. issue 1. 2022-01-20. PMID:35051025. here, we have investigated the impact of don on mouse astrocyte and microglia cell lines, as well as on primary hippocampal cultures by analysing different toxicological endpoints. 2022-01-20 2023-08-13 mouse
Yasir H Qureshi, Diego E Berman, Samuel E Marsh, Ronald L Klein, Vivek M Patel, Sabrina Simoes, Suvarnambiga Kannan, Gregory A Petsko, Beth Stevens, Scott A Smal. The neuronal retromer can regulate both neuronal and microglial phenotypes of Alzheimer's disease. Cell reports. vol 38. issue 3. 2022-01-19. PMID:35045281. moreover, the studies show that the neuronal retromer can regulate a distinct, dystrophic, microglia morphology, phenotypic of hippocampal microglia in ad. 2022-01-19 2023-08-13 mouse
Qing Tian, Hui-Ling Tang, Yi-Yun Tang, Ping Zhang, Xuan Kang, Wei Zou, Xiao-Qing Tan. Hydrogen Sulfide Attenuates the Cognitive Dysfunction in Parkinson's Disease Rats via Promoting Hippocampal Microglia M2 Polarization by Enhancement of Hippocampal Warburg Effect. Oxidative medicine and cellular longevity. vol 2022. 2022-01-14. PMID:35028004. hydrogen sulfide attenuates the cognitive dysfunction in parkinson's disease rats via promoting hippocampal microglia m2 polarization by enhancement of hippocampal warburg effect. 2022-01-14 2023-08-13 rat
Suresh B Rangasamy, Sumita Raha, Sridevi Dasarathy, Kalipada Paha. Sodium Benzoate, a Metabolite of Cinnamon and a Food Additive, Improves Cognitive Functions in Mice after Controlled Cortical Impact Injury. International journal of molecular sciences. vol 23. issue 1. 2022-01-11. PMID:35008615. oral treatment with nab, but not sodium formate (nafo), was found to decrease the activation of microglia and astrocytes and to inhibit the expression of inducible nitric oxide synthase (inos) in the hippocampus and cortex of cci-insulted mice. 2022-01-11 2023-08-13 mouse
Adelaide Fernandes, Cláudia Caldeira, Carolina Cunha, Elisabete Ferreiro, Ana Rita Vaz, Dora Brite. Differences in Immune-Related Genes Underlie Temporal and Regional Pathological Progression in 3xTg-AD Mice. Cells. vol 11. issue 1. 2022-01-11. PMID:35011699. we examined the temporal profile of inflammatory mediators and microglia deactivation/activation in the brain cortex and hippocampus of 3xtg-ad mice at 3- and 9-month-old. 2022-01-11 2023-08-13 mouse
Henrique C Campos, Deidiane Elisa Ribeiro, Debora Hashiguchi, Deborah Y Hukuda, Christiane Gimenes, Simone A A Romariz, Qing Ye, Yong Tang, Henning Ulrich, Beatriz Monteiro Long. Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease. Stem cell reviews and reports. 2022-01-08. PMID:34997526. therefore, the present study aimed to investigate whether transplantation of nsc or msc into the hippocampus of app/ps1 mice reverses ad-induced pathological alterations, evaluated by the locomotor activity (open field test), short- and long-term memory (object recognition) tests, Αβ plaques (6-e10), microglia distribution (iba-1), m1 (inos) and m2 (arg-1) microglial phenotype frequencies. 2022-01-08 2023-08-13 mouse
Henrique C Campos, Deidiane Elisa Ribeiro, Debora Hashiguchi, Deborah Y Hukuda, Christiane Gimenes, Simone A A Romariz, Qing Ye, Yong Tang, Henning Ulrich, Beatriz Monteiro Long. Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease. Stem cell reviews and reports. 2022-01-08. PMID:34997526. nsc and msc engraftment reduced the number of Αβ plaques and produced an increase in m2 microglia polarization in the hippocampus of app/ps1 mice, suggesting an anti-inflammatory effect of stem cell transplantation. 2022-01-08 2023-08-13 mouse
Henrique C Campos, Deidiane Elisa Ribeiro, Debora Hashiguchi, Deborah Y Hukuda, Christiane Gimenes, Simone A A Romariz, Qing Ye, Yong Tang, Henning Ulrich, Beatriz Monteiro Long. Distinct Effects of the Hippocampal Transplantation of Neural and Mesenchymal Stem Cells in a Transgenic Model of Alzheimer's Disease. Stem cell reviews and reports. 2022-01-08. PMID:34997526. nsc also reversed the hyperlocomotor activity and increased the number of microglia in the hippocampus of app/ps1 mice. 2022-01-08 2023-08-13 mouse
James C Nelson, Eva Greengrove, Kala N Nwachukwu, Isabella R Grifasi, S Alex Marshal. Repetitive binge-like consumption based on the Drinking-in-the-Dark model alters the microglial population in the mouse hippocampus. Journal of integrative neuroscience. vol 20. issue 4. 2022-01-08. PMID:34997716. this paper extends that research by examining the impact of binge-like consumption on microglia in the hippocampus and the amygdala. 2022-01-08 2023-08-13 mouse
James C Nelson, Eva Greengrove, Kala N Nwachukwu, Isabella R Grifasi, S Alex Marshal. Repetitive binge-like consumption based on the Drinking-in-the-Dark model alters the microglial population in the mouse hippocampus. Journal of integrative neuroscience. vol 20. issue 4. 2022-01-08. PMID:34997716. however, after three drinking-in-the-dark cycles, the number of microglia decreased in the hippocampus. 2022-01-08 2023-08-13 mouse
Risako Fujikawa, Jun Yamada, Kyoko M Iinuma, Shozo Jinn. Phytoestrogen genistein modulates neuron-microglia signaling in a mouse model of chronic social defeat stress. Neuropharmacology. 2022-01-06. PMID:34990615. the numerical densities of microglia in the hippocampus were increased by csds, and they were decreased by gen. 2022-01-06 2023-08-13 mouse