All Relations between microglial cell and hippocampus

Publication Sentence Publish Date Extraction Date Species
Jing-Yang Gu, Yao-Wei Xu, Lai-Peng Feng, Jiao Dong, Li-Qin Zhao, Cong Liu, Hui-Ying Wang, Xiang-Yang Zhang, Cai Song, Chang-Hong Wan. Enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats. Brain research bulletin. vol 177. 2021-11-18. PMID:34653561. enriched environment mitigates depressive behavior by changing the inflammatory activation phenotype of microglia in the hippocampus of depression model rats. 2021-11-18 2023-08-13 rat
Yunchang Mo, Lu Wang, Miao Ren, Wenjing Xie, Xiaoxiao Ye, Bingbing Zhou, Anqi Zhang, Qinxue Dai, Junlu Wan. Electroacupuncture prevents LPS- induced neuroinflammation via upregulation of PICK-TLR4 complexes in the microglia of hippocampus. Brain research bulletin. vol 177. 2021-11-18. PMID:34673136. electroacupuncture prevents lps- induced neuroinflammation via upregulation of pick-tlr4 complexes in the microglia of hippocampus. 2021-11-18 2023-08-13 mouse
Armin Yazdani, Belal Howidi, Meng Zhu Shi, Nicol Tugarinov, Zehra Khoja, Pia Wintermar. Sildenafil improves hippocampal brain injuries and restores neuronal development after neonatal hypoxia-ischemia in male rat pups. Scientific reports. vol 11. issue 1. 2021-11-18. PMID:34764335. treatment with sildenafil preserved the gross morphology of the hippocampus, reverted the number of mature neurons to levels comparable to sham rats, significantly increased both the immature and mature oligodendrocytes, and significantly reduced the number of microglia and astrocytes. 2021-11-18 2023-08-13 rat
Brittney Yegla, Jake Boles, Ashok Kumar, Thomas C Foste. Partial microglial depletion is associated with impaired hippocampal synaptic and cognitive function in young and aged rats. Glia. vol 69. issue 6. 2021-11-16. PMID:33586813. the role of microglia in mediating age-related changes in cognition and hippocampal synaptic function was examined by microglial depletion and replenishment using plx3397. 2021-11-16 2023-08-13 rat
Jing Wang, Quanguang Zhang, Yujiao Lu, Yan Dong, Krishnan M Dhandapani, Darrell W Brann, Robert K Y. Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:34133773. here, we show that the b-series ganglioside gd3 and its biosynthetic enzyme, gd3-synthase (gd3s), were up-regulated predominantly in the microglia of mouse hippocampus from 2 to 7 days following global cerebral ischemia (gci). 2021-11-16 2023-08-13 mouse
Jing Wang, Quanguang Zhang, Yujiao Lu, Yan Dong, Krishnan M Dhandapani, Darrell W Brann, Robert K Y. Ganglioside GD3 is up-regulated in microglia and regulates phagocytosis following global cerebral ischemia. Journal of neurochemistry. vol 158. issue 3. 2021-11-16. PMID:34133773. finally, by using a microglia-primary neuron co-culture model, we demonstrated that the gd3s-ko microglia isolated from mouse brains at 2 days after gci are less neurotoxic to co-cultured hippocampal neurons than the wt-gci microglia. 2021-11-16 2023-08-13 mouse
Vasiliy Reshetnikov, Yulia Ryabushkina, Anna Kovner, Arina Lepeshko, Natalia Bonda. Repeated and single maternal separation specifically alter microglial morphology in the prefrontal cortex and neurogenesis in the hippocampus of 15-day-old male mice. Neuroreport. vol 31. issue 18. 2021-11-15. PMID:33165192. immunohistochemical analysis was performed on slices of the hippocampus and prefrontal cortex (pfc) with antibodies against a marker of mature neurons (neun), of microglia (iba1), proliferating cells (ki67), and immature neurons (dcx). 2021-11-15 2023-08-13 mouse
Luisa Strackeljan, Ewa Baczynska, Carla Cangalaya, David Baidoe-Ansah, Jakub Wlodarczyk, Rahul Kaushik, Alexander Dityate. Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice. Cells. vol 10. issue 8. 2021-11-15. PMID:34440631. microglia depletion-induced remodeling of extracellular matrix and excitatory synapses in the hippocampus of adult mice. 2021-11-15 2023-08-13 mouse
Luisa Strackeljan, Ewa Baczynska, Carla Cangalaya, David Baidoe-Ansah, Jakub Wlodarczyk, Rahul Kaushik, Alexander Dityate. Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice. Cells. vol 10. issue 8. 2021-11-15. PMID:34440631. in the present work, we investigated the physiological role of microglia in the remodeling of perineuronal nets (pnns), predominantly associated with parvalbumin-immunopositive (pv+) interneurons, and the perisynaptic ecm around pyramidal neurons in the hippocampus. 2021-11-15 2023-08-13 mouse
Luisa Strackeljan, Ewa Baczynska, Carla Cangalaya, David Baidoe-Ansah, Jakub Wlodarczyk, Rahul Kaushik, Alexander Dityate. Microglia Depletion-Induced Remodeling of Extracellular Matrix and Excitatory Synapses in the Hippocampus of Adult Mice. Cells. vol 10. issue 8. 2021-11-15. PMID:34440631. although the elimination of microglia did not alter the overall number or intensity of pnns in the ca1 region of the hippocampus, it decreased the size of pnn holes and elevated the expression of the surrounding ecm. 2021-11-15 2023-08-13 mouse
Thit Lwin, Jenq-Lin Yang, Sukonthar Ngampramuan, Kittikun Viwatpinyo, Pongrung Chancharoen, Nisarath Veschsanit, Jitrapa Pinyomahakul, Piyarat Govitrapong, Sujira Mukd. Melatonin ameliorates methamphetamine-induced cognitive impairments by inhibiting neuroinflammation via suppression of the TLR4/MyD88/NFκB signaling pathway in the mouse hippocampus. Progress in neuro-psychopharmacology & biological psychiatry. vol 111. 2021-11-11. PMID:32941923. meth-treated mice also exhibited reactive astrocytes and activated microglia in the hippocampus. 2021-11-11 2023-08-13 mouse
Wei Wang, Rui Wang, Zhijun Jiang, Haonan Li, Zemeng Zhu, Arslan Khalid, Dexiang Liu, Fang Pa. Inhibiting Brd4 alleviated PTSD-like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats. Journal of neurochemistry. vol 158. issue 4. 2021-11-11. PMID:34050937. the results found that ifs induced ptsd-like behaviors and indicated obvious brd4 expression in microglia of the prefrontal cortex (pfc), hippocampus, and amygdala, pro-inflammatory cytokines over-expression, microglial activation, and nuclear factor-kappa b over-expression in pfc and hippocampus but not in amygdala. 2021-11-11 2023-08-13 rat
Satoshi Okuyama, Atsushi Sawamoto, Mitsunari Nakajima, Yoshiko Furukaw. [The Search for Citrus Components with Neuroprotective and Anti-dementia Effects in the Mouse Brain]. Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan. vol 141. issue 6. 2021-11-11. PMID:34078788. hmf rescued neuronal cell death in the hippocampus and suppressed the activation of microglia, whose activation have been shown to significantly aggravate neurological deficit scores for ischemic mice. 2021-11-11 2023-08-13 mouse
Giorgio Corsi, Katherine Picard, Maria Amalia di Castro, Stefano Garofalo, Federico Tucci, Giuseppina Chece, Claudio Del Percio, Maria Teresa Golia, Marcello Raspa, Ferdinando Scavizzi, Fanny Decoeur, Clotilde Lauro, Mara Rigamonti, Fabio Iannello, Davide Antonio Ragozzino, Eleonora Russo, Giovanni Bernardini, Agnès Nadjar, Marie Eve Tremblay, Claudio Babiloni, Laura Maggi, Cristina Limatol. Microglia modulate hippocampal synaptic transmission and sleep duration along the light/dark cycle. Glia. vol 70. issue 1. 2021-11-11. PMID:34487590. microglia modulate hippocampal synaptic transmission and sleep duration along the light/dark cycle. 2021-11-11 2023-08-13 mouse
Bernadette Basilico, Laura Ferrucci, Patrizia Ratano, Maria T Golia, Alfonso Grimaldi, Maria Rosito, Valentina Ferretti, Ingrid Reverte, Caterina Sanchini, Maria C Marrone, Maria Giubettini, Valeria De Turris, Debora Salerno, Stefano Garofalo, Marie-Kim St-Pierre, Micael Carrier, Massimiliano Renzi, Francesca Pagani, Brijesh Modi, Marcello Raspa, Ferdinando Scavizzi, Cornelius T Gross, Silvia Marinelli, Marie-Ève Tremblay, Daniele Caprioli, Laura Maggi, Cristina Limatola, Silvia Di Angelantonio, Davide Ragozzin. Microglia control glutamatergic synapses in the adult mouse hippocampus. Glia. vol 70. issue 1. 2021-11-11. PMID:34661306. microglia control glutamatergic synapses in the adult mouse hippocampus. 2021-11-11 2023-08-13 mouse
Bernadette Basilico, Laura Ferrucci, Patrizia Ratano, Maria T Golia, Alfonso Grimaldi, Maria Rosito, Valentina Ferretti, Ingrid Reverte, Caterina Sanchini, Maria C Marrone, Maria Giubettini, Valeria De Turris, Debora Salerno, Stefano Garofalo, Marie-Kim St-Pierre, Micael Carrier, Massimiliano Renzi, Francesca Pagani, Brijesh Modi, Marcello Raspa, Ferdinando Scavizzi, Cornelius T Gross, Silvia Marinelli, Marie-Ève Tremblay, Daniele Caprioli, Laura Maggi, Cristina Limatola, Silvia Di Angelantonio, Davide Ragozzin. Microglia control glutamatergic synapses in the adult mouse hippocampus. Glia. vol 70. issue 1. 2021-11-11. PMID:34661306. in this study, we characterized the effects of pharmacological microglia depletion, achieved by administration of plx5622, on hippocampal ca3-ca1 synapses of adult wild type mice. 2021-11-11 2023-08-13 mouse
Yicong Liu, Hui Li, Jiangqi Hu, Zhou Wu, Jie Meng, Yoshinori Hayashi, Hiroshi Nakanishi, Hong Qing, Junjun N. Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury. Molecular neurobiology. 2021-11-11. PMID:34762231. in neonatal mice brain after hi, we found par2 expression was abundant in neurons, but barely in microglia from the contralateral side of cortex and hippocampus. 2021-11-11 2023-08-13 mouse
Yicong Liu, Hui Li, Jiangqi Hu, Zhou Wu, Jie Meng, Yoshinori Hayashi, Hiroshi Nakanishi, Hong Qing, Junjun N. Differential Expression and Distinct Roles of Proteinase-Activated Receptor 2 in Microglia and Neurons in Neonatal Mouse Brain After Hypoxia-Ischemic Injury. Molecular neurobiology. 2021-11-11. PMID:34762231. conversely, par2 expression was barely in neurons while significantly increased in activated microglia from the ipsilateral side of cortex and hippocampus. 2021-11-11 2023-08-13 mouse
Wei Li, Yang Xu, Zhenghai Liu, Mengmeng Shi, Yuan Zhang, Yingcheng Deng, Xiaolin Zhong, Ling Chen, Jie He, Jiayu Zeng, Mingying Luo, Wenyu Cao, Wei Wa. TRPV4 inhibitor HC067047 produces antidepressant-like effect in LPS-induced depression mouse model. Neuropharmacology. vol 201. 2021-11-09. PMID:34637786. furthermore, trpv4 inhibitor hc067047 reduced the activation of astrocyte and microglia, decreased expression of camkii-nlrp3 inflammasome and increased the expression of neurogenesis marker dcx in the hippocampus. 2021-11-09 2023-08-13 mouse
Emanuella R Vilhena, Jéssica M Bonato, Melissa Schepers, Juliana K C Kunieda, Humberto Milani, Tim Vanmierlo, Jos Prickaerts, Rúbia M W de Oliveir. Positive effects of roflumilast on behavior, neuroinflammation, and white matter injury in mice with global cerebral ischemia. Behavioural pharmacology. vol 32. issue 6. 2021-11-05. PMID:34320520. besides, roflumilast decreased iba-1 (microglia marker) levels and increased arginase-1 (arg-1; microglia m2 phenotype marker) levels in the hippocampus of these mice. 2021-11-05 2023-08-13 mouse