All Relations between microglial cell and hippocampus

Publication Sentence Publish Date Extraction Date Species
Cong Luo, Yuji Ikegaya, Ryuta Koyam. Microglia and neurogenesis in the epileptic dentate gyrus. Neurogenesis (Austin, Tex.). vol 3. issue 1. 2021-11-03. PMID:27928548. in this review, we particularly discuss the role of microglia as the major orchestrators that regulate adult neurogenesis in the hippocampus. 2021-11-03 2023-08-13 Not clear
Yu Fujita, Kuniyuki Kano, Shigenobu Kishino, Toshihiro Nagao, Xuefeng Shen, Chiharu Sato, Hatsune Hatakeyama, Yume Ota, Sho Niibori, Ayako Nomura, Kota Kikuchi, Wataru Yasuno, Sho Takatori, Kazunori Kikuchi, Yoshitake Sano, Taisuke Tomita, Toshiharu Suzuki, Junken Aoki, Kun Zou, Shunji Natori, Hiroto Koman. Dietary cis-9, trans-11-conjugated linoleic acid reduces amyloid β-protein accumulation and upregulates anti-inflammatory cytokines in an Alzheimer's disease mouse model. Scientific reports. vol 11. issue 1. 2021-11-01. PMID:33980877. we found that c-9, t-11-cla diet-fed ad model mice significantly exhibited (1) a decrease in amyloid-β protein (aβ) levels in the hippocampus, (2) an increase in the number of microglia, and (3) an increase in the number of astrocytes expressing the anti-inflammatory cytokines, interleukin-10 and 19 (il-10, il-19), with no change in the total number of astrocytes. 2021-11-01 2023-08-13 mouse
Lingling Xie, Tianyi Li, Xiaojie Song, Hong Sun, Jie Liu, Jing Yang, Wenjie Zhao, Li Cheng, Hengsheng Chen, Benke Liu, Wei Han, Chen Yang, Li Jian. Dynamic alteration of dendrites and dendritic spines in the hippocampus and microglia in mouse brain tissues after kainate-induced status epilepticus. The International journal of neuroscience. vol 131. issue 11. 2021-10-29. PMID:32448031. dynamic alteration of dendrites and dendritic spines in the hippocampus and microglia in mouse brain tissues after kainate-induced status epilepticus. 2021-10-29 2023-08-13 mouse
Andrea Silva-Gotay, Jillian Davis, Elizabeth R Tavares, Heather N Richardso. Alcohol drinking during early adolescence activates microglial cells and increases frontolimbic Interleukin-1 beta and Toll-like receptor 4 gene expression, with heightened sensitivity in male rats compared to females. Neuropharmacology. vol 197. 2021-10-29. PMID:34252404. binge drinking alcohol activated microglia in the mpfc and hippocampus of both males and females, suggesting that voluntary alcohol exposure initiates an inflammatory response. 2021-10-29 2023-08-13 rat
Zhengrong Zhang, Zhujin Song, Fengming Shen, Pan Xie, Juan Wang, Ai-Song Zhu, Guoqi Zh. Ginsenoside Rg1 Prevents PTSD-Like Behaviors in Mice Through Promoting Synaptic Proteins, Reducing Kir4.1 and TNF-α in the Hippocampus. Molecular neurobiology. vol 58. issue 4. 2021-10-27. PMID:33215390. importantly, ginsenoside rg1 alleviated lps- or sps-stimulated expression of pro-inflammatory cytokines (il-1β and tnf-α), activation of astrocytes and microglia, and reduction of hippocampal synaptic proteins (psd95, arc, and glua1). 2021-10-27 2023-08-13 mouse
Lan Wang, Danfeng Zhao, Huan Wang, Lele Wang, Xiaohui Liu, Haiyan Zhan. FPS-ZM1 inhibits LPS-induced microglial inflammation by suppressing JAK/STAT signaling pathway. International immunopharmacology. vol 100. 2021-10-27. PMID:34509933. ameliorated proliferation and activation of microglia in the hippocampus of c57bl/6j mice subjected to lps challenge (5 mg/kg, i.p.). 2021-10-27 2023-08-13 mouse
Xianshengjie Lang, Na Zhao, Qiang He, Xun Li, Xuejiao Li, Chuanning Sun, Xianliang Zhan. Treadmill exercise mitigates neuroinflammation and increases BDNF via activation of SIRT1 signaling in a mouse model of T2DM. Brain research bulletin. vol 165. 2021-10-26. PMID:32987101. we found that treadmill exercise for 8 weeks can significantly improve the cognitive dysfunction, alleviate activation of proinflammatory microglia m1 (iba1 labeling) in the hippocampus of t2dm mice, and reduce the levels of proinflammatory factors il-1β, il-6, tnf-α, increase the expression levels of anti-inflammatory factors il-10, tgf-β1, and promote the release of bdnf. 2021-10-26 2023-08-13 mouse
Jesús Aranda, María Del Mar Fernández-Arjona, Francisco Alén, Patricia Rivera, Leticia Rubio, Inés Smith-Fernández, Francisco Javier Pavón, Antonia Serrano, Pedro J Serrano-Castro, Fernando Rodríguez de Fonseca, Juan Suáre. Sudden cessation of fluoxetine before alcohol drinking reinstatement alters microglial morphology and TLR4/inflammatory neuroadaptation in the rat brain. Brain structure & function. vol 226. issue 7. 2021-10-26. PMID:34236532. we also found that microglial cell area correlated with changes in mrna expression of chemokines (cx3cl1/fractalkine, cxcl12/sdf1α, ccl2/mcp1), cytokines (il1β, il6, il10) and the innate immune toll-like receptor 4 (tlr4) in dorsal hippocampus. 2021-10-26 2023-08-13 rat
Yan Cheng, Woong-Ki Kim, Laurie L Wellman, Larry D Sanford, Ming-Lei Gu. Short-Term Sleep Fragmentation Dysregulates Autophagy in a Brain Region-Specific Manner. Life (Basel, Switzerland). vol 11. issue 10. 2021-10-26. PMID:34685469. additionally, 5 days of sf activated microglia in the striatum but not in the hippocampus or frontal cortex. 2021-10-26 2023-08-13 mouse
Osamu Nakagawasai, Kotaro Yamada, Kohei Takahashi, Takayo Odaira, Wakana Sakuma, Daisuke Ishizawa, Naruya Takahashi, Kentaro Onuma, Chikako Hozumi, Wataru Nemoto, Koichi Tan-N. Liver hydrolysate prevents depressive-like behavior in an animal model of colitis: Involvement of hippocampal neurogenesis via the AMPK/BDNF pathway. Behavioural brain research. vol 390. 2021-10-25. PMID:32434062. hippocampal neurogenesis and morphometric changes in the microglia and astrocytes were examined by immunohistochemistry. 2021-10-25 2023-08-13 mouse
Osamu Nakagawasai, Kotaro Yamada, Kohei Takahashi, Takayo Odaira, Wakana Sakuma, Daisuke Ishizawa, Naruya Takahashi, Kentaro Onuma, Chikako Hozumi, Wataru Nemoto, Koichi Tan-N. Liver hydrolysate prevents depressive-like behavior in an animal model of colitis: Involvement of hippocampal neurogenesis via the AMPK/BDNF pathway. Behavioural brain research. vol 390. 2021-10-25. PMID:32434062. dss-treated mice showed ibd-like pathology and depressive-like behavior, a reduction in the hippocampal neuronal nuclear antigen level and neurogenesis, and increased hippocampal activation of microglia and astrocytes. 2021-10-25 2023-08-13 mouse
Mikhail Yu Stepanichev, Tatyana Goryakina, Anna Manolova, Natalia Lazareva, Alexey Kvichanskii, Liya Tretyakova, Maria Volobueva, Natalia Gulyaev. Neonatal proinflammatory challenge evokes a microglial response and affects the ratio between subtypes of GABAergic interneurons in the hippocampus of juvenile rats: sex-dependent and sex-independent effects. Brain structure & function. vol 226. issue 2. 2021-10-25. PMID:33399997. we studied effects of npc on microglia and gabaergic neuronal population of the dorsal hippocampus in juvenile male and female rats using immunofluorescent histochemistry. 2021-10-25 2023-08-13 rat
Vipan K Parihar, Munjal M Acharya, Dante E Roa, Omar Bosch, Lori-Ann Christie, Charles L Limol. Defining functional changes in the brain caused by targeted stereotaxic radiosurgery. Translational cancer research. vol 3. issue 2. 2021-10-21. PMID:24904783. neuroinflammation measured by immunostaining for activated microglia (ed1 positive cells) was significantly higher on the ipsilateral versus contralateral sides, as assessed throughout the various subfields of the hippocampus. 2021-10-21 2023-08-13 rat
Fengjuan Wang, Chuangang Li, Jianhui Shao, Jinfeng M. Sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting Wnt/β-Catenin/CaMKIV pathway. Journal of pharmacological sciences. vol 146. issue 2. 2021-10-19. PMID:33941321. sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting wnt/β-catenin/camkiv pathway. 2021-10-19 2023-08-13 rat
Fengjuan Wang, Chuangang Li, Jianhui Shao, Jinfeng M. Sevoflurane induces inflammation of microglia in hippocampus of neonatal rats by inhibiting Wnt/β-Catenin/CaMKIV pathway. Journal of pharmacological sciences. vol 146. issue 2. 2021-10-19. PMID:33941321. to investigate the effect of sevoflurane on inflammation of microglia in hippocampus of neonatal rats, and to investigate whether the related mechanism is related to wnt/β-catenin/camkiv pathway. 2021-10-19 2023-08-13 rat
Chun Wang, Wen-Rui Gao, Jing Yin, Zhao-Jun Wang, Jin-Shun Qi, Hong-Yan Cai, Mei-Na W. Chronic sleep deprivation exacerbates cognitive and synaptic plasticity impairments in APP/PS1 transgenic mice. Behavioural brain research. vol 412. 2021-10-18. PMID:34087256. the results showed that chronic sd obviously aggravated the cognitive impairments, exacerbated in vivo hippocampal long-term potentiation (ltp) suppression, reduced the expression level of psd95, increased amyloid-β (aβ) protein deposition and overactivated microglia in the hippocampus of app/ps1 mice. 2021-10-18 2023-08-13 mouse
Elena Pompili, Cinzia Fabrizi, Lorenzo Fumagalli, Francesco Forna. Autophagy in trimethyltin-induced neurodegeneration. Journal of neural transmission (Vienna, Austria : 1996). vol 127. issue 7. 2021-10-15. PMID:32451631. in the present review, we discuss the role of autophagy following intoxication with trimethyltin (tmt), an organotin compound that induces severe hippocampal neurodegeneration associated with astrocyte and microglia activation. 2021-10-15 2023-08-13 human
R L Moretti, E N Dias, S G Kiel, M C M Augusto, P S Rodrigues, A C S Sampaio, L S Medeiros, M F M Martins, I B Suffredini, C V Cardoso, E F Bonda. Behavioral and morphological effects of resveratrol and curcumin in rats submitted to doxorubicin-induced cognitive impairment. Research in veterinary science. vol 140. 2021-10-15. PMID:34536813. dox-injected rats presented short-term and long-term memory impairments as seen in the nort at 3 and 24 h after habituation and increased gfap and iba1 expression, respectively, in astrocytes and microglia of the frontal cortex, hypothalamus and hippocampus. 2021-10-15 2023-08-13 rat
Lushuang Xie, Yi Liu, Ning Zhang, Chenyu Li, Aaron F Sandhu, George Williams, Yan Shen, Hongying Li, Qiaofeng Wu, Shuguang Y. Electroacupuncture Improves M2 Microglia Polarization and Glia Anti-inflammation of Hippocampus in Alzheimer's Disease. Frontiers in neuroscience. vol 15. 2021-10-15. PMID:34646113. electroacupuncture improves m2 microglia polarization and glia anti-inflammation of hippocampus in alzheimer's disease. 2021-10-15 2023-08-13 Not clear
Feng Zhou, Xian Wang, Baoyu Han, Xiaohui Tang, Ru Liu, Qing Ji, Zhiqiang Zhou, Lidong Zhan. Short-chain fatty acids contribute to neuropathic pain via regulating microglia activation and polarization. Molecular pain. vol 17. 2021-10-14. PMID:33626986. the levels of microglia markers including ionized calcium-binding adaptor molecule 1 (iba1), cluster of differentiation 11b (cd11b), pro-inflammatory phenotype markers including cd68, interleukin-1β (il-1β), tumor necrosis factor-α (tnf-α), and anti-inflammatory phenotype markers including cd206, il-4 in the hippocampus and spinal cord were determined on day 21 after cci. 2021-10-14 2023-08-13 mouse