All Relations between microglial cell and prefrontal cortex

Reference Sentence Publish Date Extraction Date Species
Kelly Barko, Micah Shelton, Xiangning Xue, Yvette Afriyie-Agyemang, Stephanie Puig, Zachary Freyberg, George C Tseng, Ryan W Logan, Marianne L Sene. Brain region- and sex-specific transcriptional profiles of microglia. Frontiers in psychiatry vol 13 issue 2022 36090351 transcripts more highly expressed in pfc isolated microglia were enriched for synapse-related pathways while microglia isolated from the striatum were enriched for pathways related to microtubule polymerization. 2022-09-12 2022-09-14 Not clear
Kelly Barko, Micah Shelton, Xiangning Xue, Yvette Afriyie-Agyemang, Stephanie Puig, Zachary Freyberg, George C Tseng, Ryan W Logan, Marianne L Sene. Brain region- and sex-specific transcriptional profiles of microglia. Frontiers in psychiatry vol 13 issue 2022 36090351 we also found evidence for a gradient of expression of microglia-specific transcripts across the rostral-to-caudal axes of the brain, with microglia extracted from the striatum exhibiting a transcriptional profile intermediate between that of the pfc and midbrain. 2022-09-12 2022-09-14 Not clear
Jelena Martinovic, Marina Zaric Kontic, Milorad Dragic, Ana Todorovic, Ivana Gusevac Stojanovic, Natasa Mitrovic, Ivana Grkovic, Dunja Drakuli. Chronic oral d-galactose intake provokes age-related changes in the rat prefrontal cortex. Behavioural brain research vol issue 2022 36030906 in the pfc, analysis of microglia revealed reduction of branching pattern following d-gal intake, in parallel with increased oxidative damage of proteins, lipids and disturbed pro-oxidant antioxidant balance. 2022-08-28 2022-08-31 Not clear
Leonardo C Souza, Marcos K Andrade, Evellyn M Azevedo, Daniele C Ramos, Ellen L Bail, Maria A B F Vita. Andrographolide Attenuates Short-Term Spatial and Recognition Memory Impairment and Neuroinflammation Induced by a Streptozotocin Rat Model of Alzheimer's Disease. Neurotoxicity research vol issue 2022 36029454 in the present study, we investigated the effects of andro in the icv-stz model relative to short-term spatial memory (object location test (olt) and y maze test), short-term recognition memory (object recognition test (ort)), locomotor activity (open field test (oft)), expression of amyloid precursor protein (app), and activation of astrocytes (glial fibrillary acidic protein (gfap) expression) and microglia (ionized calcium-binding adapter molecule-1 (iba-1) immunohistochemistry) in the prefrontal cortex (pfc) and hippocampus (hip). 2022-08-27 2022-08-29 Not clear
Ana Lopes-Rocha, Thiago Ohno Bezerra, Roberta Zanotto, Inda Lages Nascimento, Angela Rodrigues, Cristiane Salu. The Antioxidant N-Acetyl-L-Cysteine Restores the Behavioral Deficits in a Neurodevelopmental Model of Schizophrenia Through a Mechanism That Involves Nitric Oxide. Frontiers in pharmacology vol 13 issue 2022 35903343 analyses of markers involved in the inflammatory response, such as astrocytes (glial fibrillary acid protein, gfap) and microglia (binding adapter molecule 1, iba1), and parvalbumin (pv) positive gabaergic, were conducted in the prefrontal cortex [pfc, medial orbital cortex (mo) and prelimbic cortex (prl)] and dorsal and ventral hippocampus [ca1, ca2, ca3, and dentate gyrus (dg)] in rats under chronic treatment with nac. 2022-07-29 2022-08-08 Not clear
Yishun Hong, Wenyao Wu, Shuo Wang, Quanshui Hao, Hua Zheng, Shiyong Li, Xianwei Zhang, Rao Su. Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord. Neuropharmacology vol 196 issue 2021 34252405 our results showed that sps exposure increased the levels of angiotensin ii in the hippocampus, prefrontal cortex (pfc) and spinal cord; intraperitoneal injection of losartan attenuated sps-induced mechanical allodynia, and suppressed sps-induced glial activation (both microglia and astrocytes) and proinflammatory cytokine expression in the pfc and spinal cord, but not in the hippocampus. 2022-02-02 2022-01-13 Not clear
Amy C Reichelt, Claire A Lemieux, Oren Princz-Lebel, Ashmita Singh, Timothy J Bussey, Lisa M Saksid. Age-dependent and region-specific alteration of parvalbumin neurons, perineuronal nets and microglia in the mouse prefrontal cortex and hippocampus following obesogenic diet consumption. Scientific reports vol 11 issue 1 2021 33692414 hfhs diet increased microgliosis in the adult cohort, and morphological changes to microglia were observed in the pfc and hippocampus of the adolescent cohort, with a shift to activated microglia phenotypes. 2021-11-22 2022-01-13 Not clear
Noriyoshi Usui, Yuta Ono, Ryoko Aramaki, Stefano Berto, Genevieve Konopka, Hideo Matsuzaki, Shoichi Shimad. Early Life Stress Alters Gene Expression and Cytoarchitecture in the Prefrontal Cortex Leading to Social Impairment and Increased Anxiety. Frontiers in genetics vol 12 issue 2021 34795694 in histological analysis, we found a reduced number of neurons and an increased number of microglia in the pfc of els mice. 2021-11-20 2022-01-13 Not clear
Vasiliy Reshetnikov, Yulia Ryabushkina, Anna Kovner, Arina Lepeshko, Natalia Bonda. Repeated and single maternal separation specifically alter microglial morphology in the prefrontal cortex and neurogenesis in the hippocampus of 15-day-old male mice. Neuroreport vol 31 issue 18 2021 33165192 immunohistochemical analysis was performed on slices of the hippocampus and prefrontal cortex (pfc) with antibodies against a marker of mature neurons (neun), of microglia (iba1), proliferating cells (ki67), and immature neurons (dcx). 2021-11-15 2022-01-13 Not clear
Vasiliy Reshetnikov, Yulia Ryabushkina, Anna Kovner, Arina Lepeshko, Natalia Bonda. Repeated and single maternal separation specifically alter microglial morphology in the prefrontal cortex and neurogenesis in the hippocampus of 15-day-old male mice. Neuroreport vol 31 issue 18 2021 33165192 we found higher density of ameboid microglia and intermediate microglia in the pfc in groups ms and md, respectively, than in a control group. 2021-11-15 2022-01-13 Not clear
Milo\\xc5\\xa1 Vratari\\xc4\\x87, Vladimir \\xc5\\xa0enk, Biljana Bursa\\xc4\\x87, Ljupka Gligorovska, Djurdjica Ignjatovi\\xc4\\x87, Sanja Kova\\xc4\\x8devi\\xc4\\x87, Nata\\xc5\\xa1a Veli\\xc4\\x8dkovi\\xc4\\x87, Ana Djordjevi. Fructose diet ameliorates effects of macrophage migration inhibitory factor deficiency on prefrontal cortex inflammation, neural plasticity, and behavior in male mice. BioFactors (Oxford, England) vol issue 2021 34767656 the results showed concomitant increase of tnf-\xce\xb1, tlr-4, myd88 and m2 microglia markers (arg-1, mrc-1, lif) in the pfc of mif-ko, paralleled with unchanged glucocorticoid and insulin signaling. 2021-11-12 2022-01-13 Not clear
Wei Wang, Rui Wang, Zhijun Jiang, Haonan Li, Zemeng Zhu, Arslan Khalid, Dexiang Liu, Fang Pa. Inhibiting Brd4 alleviated PTSD-like behaviors and fear memory through regulating immediate early genes expression and neuroinflammation in rats. Journal of neurochemistry vol 158 issue 4 2021 34050937 the results found that ifs induced ptsd-like behaviors and indicated obvious brd4 expression in microglia of the prefrontal cortex (pfc), hippocampus, and amygdala, pro-inflammatory cytokines over-expression, microglial activation, and nuclear factor-kappa b over-expression in pfc and hippocampus but not in amygdala. 2021-11-11 2022-01-13 Not clear
Pamela Reyes-Ortega, Durairaj Ragu Varman, Ver\\xc3\\xb3nica M Rodr\\xc3\\xadguez, Daniel Reyes-Har. Anorexia induces a microglial associated pro-inflammatory environment and correlates with neurodegeneration in the prefrontal cortex of young female rats. Behavioural brain research vol 392 issue 2021 32387351 in this study we tested if anorexia induces a pro-inflammatory environment associated with microglia in the medial prefrontal cortex (mpfc) and orbitofrontal cortex (ofc), specific subregions of the pfc involved in appetite. 2021-10-13 2022-01-13 Not clear
Yishun Hong, Wenyao Wu, Shuo Wang, Quanshui Hao, Hua Zheng, Shiyong Li, Xianwei Zhang, Rao Su. Angiotensin II type 1 receptor blockade attenuates posttraumatic stress disorder-related chronic pain by inhibiting glial activation in the spinal cord. Neuropharmacology vol 196 issue 2021 34252405 our results showed that sps exposure increased the levels of angiotensin ii in the hippocampus, prefrontal cortex (pfc) and spinal cord; intraperitoneal injection of losartan attenuated sps-induced mechanical allodynia, and suppressed sps-induced glial activation (both microglia and astrocytes) and proinflammatory cytokine expression in the pfc and spinal cord, but not in the hippocampus. 2021-10-01 2022-01-13 Not clear
Ronak Mousaviyan, Nahid Davoodian, Faezeh Alizadeh, Maryam Ghasemi-Kasman, Seyed Abdollah Mousavi, Fatemeh Shaerzadeh, Haniyeh Kazem. Zinc Supplementation During Pregnancy Alleviates Lipopolysaccharide-Induced Glial Activation and Inflammatory Markers Expression in a Rat Model of Maternal Immune Activation. Biological trace element research vol 199 issue 11 2021 33400154 at postnatal day 60, the density of both microglia and astrocyte cells and the expression levels of il-6, il-1\xce\xb2, inos, tnf-\xce\xb1, nf-\xce\xbab, and gfap were evaluated in the pfc of male pups. 2021-09-27 2022-01-13 Not clear
Ronak Mousaviyan, Nahid Davoodian, Faezeh Alizadeh, Maryam Ghasemi-Kasman, Seyed Abdollah Mousavi, Fatemeh Shaerzadeh, Haniyeh Kazem. Zinc Supplementation During Pregnancy Alleviates Lipopolysaccharide-Induced Glial Activation and Inflammatory Markers Expression in a Rat Model of Maternal Immune Activation. Biological trace element research vol 199 issue 11 2021 33400154 although maternal lps treatment increased microglia and astrocyte density, number of neurons in the pfc of adult offspring remained unchanged. 2021-09-27 2022-01-13 Not clear
Ronak Mousaviyan, Nahid Davoodian, Faezeh Alizadeh, Maryam Ghasemi-Kasman, Seyed Abdollah Mousavi, Fatemeh Shaerzadeh, Haniyeh Kazem. Zinc Supplementation During Pregnancy Alleviates Lipopolysaccharide-Induced Glial Activation and Inflammatory Markers Expression in a Rat Model of Maternal Immune Activation. Biological trace element research vol 199 issue 11 2021 33400154 maternal zinc supplementation alleviated increased expression levels of inflammatory mediators and microglia and astrocyte density induced by lps in the pfc of treated offspring. 2021-09-27 2022-01-13 Not clear
Marina Gabaglio, Erica Zamberletti, Cristina Manenti, Daniela Parolaro, Tiziana Rubin. Long-Term Consequences of Adolescent Exposure to THC-Rich/CBD-Poor and CBD-Rich/THC-Poor Combinations: A Comparison with Pure THC Treatment in Female Rats. International journal of molecular sciences vol 22 issue 16 2021 34445602 cbd content is able to mitigate some of the long-term behavioral alterations induced by adolescent thc exposure as well as long-term changes in cb1 receptor and microglia activation in the prefrontal cortex (pfc). 2021-09-20 2022-01-13 Not clear
Yong Yang, Tamaki Ishima, Xiayun Wan, Yan Wei, Lijia Chang, Jiancheng Zhang, Youge Qu, Kenji Hashimot. Microglial depletion and abnormalities in gut microbiota composition and short-chain fatty acids in mice after repeated administration of colony stimulating factor 1 receptor inhibitor PLX5622. European archives of psychiatry and clinical neuroscience vol issue 2021 34480631 repeated administration of plx5622 caused significant reductions of the expression of genes and proteins for microglial markers in the prefrontal cortex (pfc) and hippocampus compared to control mice although the elimination of brain's microglia was partial. 2021-09-04 2022-01-14 Not clear
Marianela Evelyn Traetta, Nonthu\\xc3\\xa9 Alejandra Uccelli, Sandra Cristina Z\\xc3\\xa1rate, Dante G\\xc3\\xb3mez Cuautle, Alberto Javier Ramos, Anal\\xc3\\xada Rein\\xc3\\xa9. Long-Lasting Changes in Glial Cells Isolated From Rats Subjected to the Valproic Acid Model of Autism Spectrum Disorder. Frontiers in pharmacology vol 12 issue 2021 34421599 or saline (control) at embryonic day 10.5 were used to study synapses, microglia, and astroglia in the prefrontal cortex (pfc) at postnatal days 3 and 35 (pnd3 and pnd35). 2021-08-24 2022-01-13 Not clear
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