| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. |
2020-09-30 |
2023-08-13 |
human |
| Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
for immunodetection of spinal cord dorsal horn microglia, a polyclonal rabbit antibody against a synthetic peptide corresponding to the c-terminus of ionized calcium-binding adaptor molecule 1 (iba-1) was used. |
2020-09-30 |
2023-08-13 |
human |
| Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
evaluation of shape, area, cell diameter, cell process length and thickness was performed on dorsal horn microglia and astrocyte. |
2020-09-30 |
2023-08-13 |
human |
| Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
iba-1 and gfap/cx-43 can successfully immune-label microglia and astrocytes respectively in horse spinal cords, and thus reveal cell morphology and corresponding distribution within the dorsal horn laminae of healthy horses. |
2020-09-30 |
2023-08-13 |
human |
| Constanza Stefania Meneses, Heine Yacob Müller, Daniel Eduardo Herzberg, Benjamín Uberti, Hedie Almagro Bustamante, Marianne Patricia Werne. Immunofluorescence characterization of spinal cord dorsal horn microglia and astrocytes in horses. PeerJ. vol 5. 2020-09-30. PMID:29085760. |
microglia and astrocytes were found in the more superficial regions of the dorsal horn, similarly to that previously observed in humans and rodents. |
2020-09-30 |
2023-08-13 |
human |
| Emiko Senba, Katsuya Kam. A new aspect of chronic pain as a lifestyle-related disease. Neurobiology of pain (Cambridge, Mass.). vol 1. 2020-09-29. PMID:31194049. |
epigenetic changes in activated microglia and maintained gaba synthesis in the spinal dorsal horn may contribute to eih. |
2020-09-29 |
2023-08-13 |
mouse |
| Jiang Wu, Mark Hocevar, Bihua Bie, Joseph F Foss, Mohamed Nagui. Cannabinoid Type 2 Receptor System Modulates Paclitaxel-Induced Microglial Dysregulation and Central Sensitization in Rats. The journal of pain. vol 20. issue 5. 2020-08-19. PMID:30414958. |
we tested the hypothesis that activation of cb2 receptor by mda7 modulates microglial dysregulation, suppresses the overexpression of brain-derived neurotrophic factor (bdnf) in microglia in the dorsal horn, and attenuates the central sensitization and pain behavior induced by paclitaxel. |
2020-08-19 |
2023-08-13 |
rat |
| Jiang Wu, Mark Hocevar, Bihua Bie, Joseph F Foss, Mohamed Nagui. Cannabinoid Type 2 Receptor System Modulates Paclitaxel-Induced Microglial Dysregulation and Central Sensitization in Rats. The journal of pain. vol 20. issue 5. 2020-08-19. PMID:30414958. |
paclitaxel induced the expression of cb2 receptors and production of interleukin (il)-6 in microglia in the dorsal horn. |
2020-08-19 |
2023-08-13 |
rat |
| Li-Jun Zhou, Jiyun Peng, Ya-Nan Xu, Wei-Jie Zeng, Jun Zhang, Xiao Wei, Chun-Lin Mai, Zhen-Jia Lin, Yong Liu, Madhuvika Murugan, Ukpong B Eyo, Anthony D Umpierre, Wen-Jun Xin, Tao Chen, Mingtao Li, Hui Wang, Jason R Richardson, Zhi Tan, Xian-Guo Liu, Long-Jun W. Microglia Are Indispensable for Synaptic Plasticity in the Spinal Dorsal Horn and Chronic Pain. Cell reports. vol 27. issue 13. 2020-07-30. PMID:31242418. |
microglia are indispensable for synaptic plasticity in the spinal dorsal horn and chronic pain. |
2020-07-30 |
2023-08-13 |
mouse |
| Hidetoshi Tozaki-Saitoh, Makoto Tsud. Microglia-neuron interactions in the models of neuropathic pain. Biochemical pharmacology. vol 169. 2020-07-13. PMID:31445020. |
microglia, a type of immune cell in the central nervous system, has attracted researchers' attention because in rodent models of neuropathic pain that develop strong mechanical and thermal hypersensitivity, histologically activated microglia are seen in the dorsal horn of spinal cord. |
2020-07-13 |
2023-08-13 |
Not clear |
| Ulrich Hoheisel, Marucia Chacur, Rolf-Detlef Treede, Siegfried Mens. Action potentials and subthreshold potentials of dorsal horn neurons in a rat model of myositis: a study employing intracellular recordings in vivo. Journal of neurophysiology. vol 122. issue 2. 2020-05-07. PMID:31166805. |
intracellular in vivo recordings from rat dorsal horn neurons were made to study the contribution of microglia to the central sensitization of spinal synapses induced by a chronic muscle inflammation. |
2020-05-07 |
2023-08-13 |
rat |
| Ulrich Hoheisel, Marucia Chacur, Rolf-Detlef Treede, Siegfried Mens. Action potentials and subthreshold potentials of dorsal horn neurons in a rat model of myositis: a study employing intracellular recordings in vivo. Journal of neurophysiology. vol 122. issue 2. 2020-05-07. PMID:31166805. |
the aim was to test whether an inflammation-induced sensitization of dorsal horn neurons is mediated by changes in synaptic strength or other synaptic changes and how activated microglia influence these processes. |
2020-05-07 |
2023-08-13 |
rat |
| Xiaobing Yu, Hongju Liu, Katherine A Hamel, Maelig G Morvan, Stephen Yu, Jacqueline Leff, Zhonghui Guan, Joao M Braz, Allan I Basbau. Dorsal root ganglion macrophages contribute to both the initiation and persistence of neuropathic pain. Nature communications. vol 11. issue 1. 2020-04-23. PMID:31937758. |
paralleling the activation of dorsal horn microglia after peripheral nerve injury is a significant expansion and proliferation of macrophages around injured sensory neurons in dorsal root ganglia (drg). |
2020-04-23 |
2023-08-13 |
mouse |
| Tingting Yu, Xin Zhang, Haosong Shi, Jinge Tian, Lingling Sun, Xueming Hu, Wenqiang Cui, Dongping D. P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents. Cell death & disease. vol 10. issue 3. 2020-04-20. PMID:30778044. |
p2y12 receptors on microglia are thought to be a key player in the surveillance of the local environment, but whether or how these receptors are engaged in the cross-talk between microglia and neurons of the dorsal horn remain ambiguous. |
2020-04-20 |
2023-08-13 |
mouse |
| Tingting Yu, Xin Zhang, Haosong Shi, Jinge Tian, Lingling Sun, Xueming Hu, Wenqiang Cui, Dongping D. P2Y12 regulates microglia activation and excitatory synaptic transmission in spinal lamina II neurons during neuropathic pain in rodents. Cell death & disease. vol 10. issue 3. 2020-04-20. PMID:30778044. |
we found that spinal nerve ligation (snl) significantly increased the level of p2y12 receptors specifically in the microglia of the ipsilateral dorsal horn. |
2020-04-20 |
2023-08-13 |
mouse |
| Ágnes Hunyady, Zsófia Hajna, Tímea Gubányi, Bálint Scheich, Ágnes Kemény, Balázs Gaszner, Éva Borbély, Zsuzsanna Helye. Hemokinin-1 is an important mediator of pain in mouse models of neuropathic and inflammatory mechanisms. Brain research bulletin. vol 147. 2020-04-06. PMID:30664920. |
microglia, but not astrocyte activation was observed 14 days after psl in the ipsilateral spinal dorsal horn of wildtype, but not hk-1-deficient mice. |
2020-04-06 |
2023-08-13 |
mouse |
| Zsuzsanna Helyes, Valéria Tékus, Nikolett Szentes, Krisztina Pohóczky, Bálint Botz, Tamás Kiss, Ágnes Kemény, Zsuzsanna Környei, Krisztina Tóth, Nikolett Lénárt, Hajnalka Ábrahám, Emmanuel Pinteaux, Sheila Francis, Serena Sensi, Ádám Dénes, Andreas Goebe. Transfer of complex regional pain syndrome to mice via human autoantibodies is mediated by interleukin-1-induced mechanisms. Proceedings of the National Academy of Sciences of the United States of America. vol 116. issue 26. 2020-04-06. PMID:31182576. |
after a short-lasting paw inflammatory response in all groups, crps igg-injected mice displayed sustained, profound microglia and astrocyte activation in the dorsal horn of the spinal cord and pain-related brain regions, indicating central sensitization. |
2020-04-06 |
2023-08-13 |
mouse |
| Wei Wang, Xiongxiong Zhong, Yongyong Li, Ruixian Guo, Sujuan Du, Lili Wen, Yanlu Ying, Tao Yang, Xu-Hong We. Rostral ventromedial medulla-mediated descending facilitation following P2X7 receptor activation is involved in the development of chronic post-operative pain. Journal of neurochemistry. vol 149. issue 6. 2020-03-13. PMID:30570747. |
the microinjection of the p2x7r agonist bzatp, the nadph oxidase activator phorbol-12-myristate-13-acetate, or il-1β into the rvm induced bilateral mechanical allodynia, microglia activation, and 5-ht release in the l3 spinal dorsal horn. |
2020-03-13 |
2023-08-13 |
rat |
| Ana Carolina Pinheiro Campos, Miriã Benatti Berzuino, Marina Sorrentino Hernandes, Erich Talamoni Fonoff, Rosana Lima Pagan. Monoaminergic regulation of nociceptive circuitry in a Parkinson's disease rat model. Experimental neurology. vol 318. 2020-03-02. PMID:31028827. |
through immunohistochemistry, the number and activation of neurons, and the staining for astrocytes, microglia and enkephalin were evaluated in specific brain structures and the dorsal horn of the spinal cord. |
2020-03-02 |
2023-08-13 |
rat |
| Yuya Kawarai, Sumihisa Orita, Junichi Nakamura, Shuichi Miyamoto, Miyako Suzuki, Kazuhide Inage, Shigeo Hagiwara, Takane Suzuki, Takayuki Nakajima, Tsutomu Akazawa, Seiji Ohtor. Analgesic Effect of Duloxetine on an Animal Model of Monosodium Iodoacetate-Induced Hip Osteoarthritis. Journal of orthopaedic research : official publication of the Orthopaedic Research Society. vol 38. issue 2. 2020-02-10. PMID:31538672. |
a single injection of duloxetine significantly attenuated it in induced hip oa (p < 0.05) and suppressed the number of iba1-ir microglia of the ipsilateral dorsal horn (p < 0.05). |
2020-02-10 |
2023-08-13 |
rat |