All Relations between microglial cell and spinal cord posterior horn

Reference Sentence Publish Date Extraction Date Species
Masayuki Miyagi, Tetsuhiro Ishikawa, Hiroto Kamoda, Miyako Suzuki, Gen Inoue, Yoshihiro Sakuma, Yasuhiro Oikawa, Kentaro Uchida, Takane Suzuki, Kazuhisa Takahashi, Masashi Takaso, Seiji Ohtor. The efficacy of nerve growth factor antibody in a mouse model of neuropathic cancer pain. Experimental animals vol 65 issue 4 2017 27194075 cgrp and atf-3-immunoreactivity in drgs and microglia expression in the spinal dorsal horn were upregulated in the saline group compared with the sham group, and they were suppressed in the anti-ngf group compared with the saline group (p<0.05). 2017-03-02 2022-01-12 Not clear
Peter M Grace, Keith A Strand, Erika L Galer, Daniel J Urban, Xiaohui Wang, Michael V Baratta, Timothy J Fabisiak, Nathan D Anderson, Kejun Cheng, Lisa I Greene, Debra Berkelhammer, Yingning Zhang, Amanda L Ellis, Hang Hubert Yin, Serge Campeau, Kenner C Rice, Bryan L Roth, Steven F Maier, Linda R Watkin. Morphine paradoxically prolongs neuropathic pain in rats by amplifying spinal NLRP3 inflammasome activation. Proceedings of the National Academy of Sciences of the United States of America vol 113 issue 24 2017 27247388 as spinal dorsal horn microglia expressed this signaling platform, these cells were selectively inhibited in vivo after transfection with a novel designer receptor exclusively activated by designer drugs (dreadd). 2017-01-26 2022-01-12 Not clear
Liying Bai, Xinru Wang, Zhisong Li, Cunlong Kong, Yonghui Zhao, Jun-Liang Qian, Quancheng Kan, Wei Zhang, Ji-Tian X. Upregulation of Chemokine CXCL12 in the Dorsal Root Ganglia and Spinal Cord Contributes to the Development and Maintenance of Neuropathic Pain Following Spared Nerve Injury in Rats. Neuroscience bulletin vol 32 issue 1 2016 26781879 sni also induced long-lasting upregulation of cxcl12 and cxcr4 in the ipsilateral l4-5 spinal cord dorsal horn, characterized by cxcl12 expression in neurons and microglia, and cxcr4 expression in neurons and astrocytes. 2016-11-03 2022-01-12 Not clear
Josiane C S Mapplebeck, Simon Beggs, Michael W Salte. Sex differences in pain: a tale of two immune cells. Pain vol 157 Suppl 1 issue 2016 26785152 despite similar microglia proliferation in the dorsal horn in both sexes, females do not upregulate p2x4rs and use a microglia-independent pathway to mediate pain hypersensitivity. 2016-10-17 2022-01-12 Not clear
Hee Kyung Cho, Sang Ho Ahn, So-Yeon Kim, Mi-Jung Choi, Se Jin Hwang, Yun Woo Ch. Changes in the Expressions of Iba1 and Calcitonin Gene-Related Peptide in Adjacent Lumbar Spinal Segments after Lumbar Disc Herniation in a Rat Model. Journal of Korean medical science vol 30 issue 12 2016 26713069 it was found immunoreactivity for iba1-positive microglia was higher in the l5 (p=0.004) dorsal horn and in the ipsilateral l4 (p=0.009), l6 (p=0.002), and s1 (p=0.002) dorsal horns in the np-exposed group than in the sham-operated group. 2016-10-06 2022-01-12 Not clear
J Jung, N Uesugi, N Y Jeong, B S Park, H Konishi, H Kiyam. Increase of transcription factor EB (TFEB) and lysosomes in rat DRG neurons and their transportation to the central nerve terminal in dorsal horn after nerve injury. Neuroscience vol 313 issue 2016 26601776 in the spinal dorsal horn (dh), nerve injury activates microglia and induces neuropathic pain. 2016-09-30 2022-01-12 Not clear
Yi Liang, Yujie Qiu, Junying Du, Jin Liu, Junfan Fang, Ji Zhu, Jianqiao Fan. Inhibition of spinal microglia and astrocytes contributes to the anti-allodynic effect of electroacupuncture in neuropathic pain induced by spinal nerve ligation. Acupuncture in medicine : journal of the British Medical Acupuncture Society vol 34 issue 1 2016 26177687 besides neurons, activated microglia and astrocytes in the spinal cord dorsal horn (scdh) contribute to the pathogenesis of chronic pain. 2016-09-23 2022-01-12 Not clear
Hui Fan, Teng-Fei Li, Nian Gong, Yong-Xiang Wan. Shanzhiside methylester, the principle effective iridoid glycoside from the analgesic herb Lamiophlomis rotata, reduces neuropathic pain by stimulating spinal microglial \\xce\\xb2-endorphin expression. Neuropharmacology vol 101 issue 2016 26363192 in the spinal dorsal horn and primary microglia, sm significantly evoked \xce\xb2-endorphin expression, which was completely prevented by the microglial inhibitor minocycline and p38 mitogen-activated protein kinase (mapk) inhibitor sb203580. 2016-09-22 2022-01-12 Not clear
Young Chan Jeong, Ji Seon Son, Young Bae Kwo. The spinal antinociceptive mechanism determined by systemic administration of BD1047 in zymosan-induced hyperalgesia in rats. Brain research bulletin vol 119 issue Pt A 2016 26434709 zymosan also led to increased cd11b immunoreactivity (a marker of microglia) accompanied by 'phosphorylated p38 mitogen activated protein kinase' (p-p38mapk) and interleukin-1\xce\xb2immunoreactivity in the spinal dorsal horn. 2016-08-29 2022-01-12 Not clear
Sasan Gazerani, Jalal Zaringhalam, Homa Manaheji, Sahar Golab. The Role of C Fibers in Spinal Microglia Induction and Possible Relation with TRPV3 Expression During Chronic Inflammatory Arthritis in Rats. Basic and clinical neuroscience vol 7 issue 3 2016 27563416 stimulation of peptidergic fibers activates microglia in the dorsal horn. 2016-08-26 2022-01-12 Not clear
Dongmei Wang, Yaping Xue, Yajuan Chen, Liqin Ruan, Yanguo Hon. Mas-related gene (Mrg) C receptors inhibit mechanical allodynia and spinal microglia activation in the early phase of neuropathic pain in rats. Neuroscience letters vol 618 issue 2016 26952974 bam8-22 (10 nmol) inhibited snl-induced microglia activation in the spinal dorsal horn on day 2 post-snl. 2016-08-22 2022-01-12 Not clear
Dongmei Wang, Yaping Xue, Yajuan Chen, Liqin Ruan, Yanguo Hon. Mas-related gene (Mrg) C receptors inhibit mechanical allodynia and spinal microglia activation in the early phase of neuropathic pain in rats. Neuroscience letters vol 618 issue 2016 26952974 these results suggest that the activation of mrgc receptors can relieve pain hypersensitivity by the inhibition of nnos increase in drg neurons and microglia activation in the spinal dorsal horn in the early time following peripheral nerve injury. 2016-08-22 2022-01-12 Not clear
Norimitsu Morioka, Fang Fang Zhang, Yoki Nakamura, Tomoya Kitamura, Kazue Hisaoka-Nakashima, Yoshihiro Nakat. Tumor necrosis factor-mediated downregulation of spinal astrocytic connexin43 leads to increased glutamatergic neurotransmission and neuropathic pain in mice. Brain, behavior, and immunity vol 49 issue 2016 26116449 in mice, cx43 is mainly expressed in astrocytes, not neurons or microglia, in the spinal dorsal horn. 2016-06-07 2022-01-12 Not clear
V\\xc3\\xadctor M L\\xc3\\xb3pez-\\xc3\\x81lvarez, Laura Modol, Xavier Navarro, Stefano Cobianch. Early increasing-intensity treadmill exercise reduces neuropathic pain by preventing nociceptor collateral sprouting and disruption of chloride cotransporters homeostasis after peripheral nerve injury. Pain vol 156 issue 9 2016 26090759 itr normalized nkcc1 and boosted kcc2 expression, together with a significant reduction of microgliosis in l3-l5 dorsal horn, and a reduction of bdnf expression in microglia at 1 to 2 weeks postinjury. 2016-05-17 2022-01-12 Not clear
William Galbavy, Martin Kaczocha, Michelino Puopolo, Lixin Liu, Mario J Rebecch. Neuroimmune and Neuropathic Responses of Spinal Cord and Dorsal Root Ganglia in Middle Age. PloS one vol 10 issue 8 2016 26241743 immunofluorescence images of dorsal horn microglia from middle-aged na\xc3\xafve or sham rats were typically hypertrophic with mostly thickened, de-ramified processes, similar to microglia following cci. 2016-05-10 2022-01-12 Not clear
Nian Liu, Kai-Kai Zang, Yu-Qiu Zhan. [Activation of microglia and astrocytes in different spinal segments after peripheral nerve injury in mice]. Sheng li xue bao : [Acta physiologica Sinica] vol 67 issue 6 2016 26701632 however, little is known about the expression patterns of activated microglia and astrocytes in the spinal dorsal horn. 2016-05-03 2022-01-12 Not clear
Yuya Yamamoto, Ryuji Terayama, Noriko Kishimoto, Kotaro Maruhama, Masahide Mizutani, Seiji Iida, Tomosada Sugimot. Activated microglia contribute to convergent nociceptive inputs to spinal dorsal horn neurons and the development of neuropathic pain. Neurochemical research vol 40 issue 5 2016 25784443 activated microglia contribute to convergent nociceptive inputs to spinal dorsal horn neurons and the development of neuropathic pain. 2016-04-01 2022-01-12 Not clear
Yuya Yamamoto, Ryuji Terayama, Noriko Kishimoto, Kotaro Maruhama, Masahide Mizutani, Seiji Iida, Tomosada Sugimot. Activated microglia contribute to convergent nociceptive inputs to spinal dorsal horn neurons and the development of neuropathic pain. Neurochemical research vol 40 issue 5 2016 25784443 the activation of microglia in the spinal dorsal horn following peripheral nerve injury has been reported previously, and this change has been proposed to contribute to the development of a neuropathic pain state. 2016-04-01 2022-01-12 Not clear
Qian Song, Ming-Gang Liu, Min Zhu. Minocycline does not affect long-term potentiation in the anterior cingulate cortex of normal adult mice. Molecular pain vol 11 issue 2016 25933605 it has been reported that activated microglia plays important roles in chronic pain-related sensory signaling at the spinal cord dorsal horn. 2016-03-08 2022-01-12 Not clear
Yan Shen, Zhi-Jun Zhang, Ming-Di Zhu, Bao-Chun Jiang, Tian Yang, Yong-Jing Ga. Exogenous induction of HO-1 alleviates vincristine-induced neuropathic pain by reducing spinal glial activation in mice. Neurobiology of disease vol 79 issue 2016 25956228 immunostaining showed that ho-1 was mainly expressed in neurons of spinal cord dorsal horn in na\xc3\xafve animals, but induced in astrocytes and microglia after vincristine injection. 2016-03-02 2022-01-12 Not clear
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