| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Valerie Joers, Benjamin C Murray, Caroline McLaughlin, Danielle Oliver, Hannah Staley, Jazmyn Coronado, Cindy Achat-Mendes, Sanam Golshani, Sean D Kelly, Matthew Goodson, Danica Lee, Fredric P Manfredsson, Bob M Moore, Malú Gámez Tanse. Modulation of cannabinoid receptor 2 alters neuroinflammation and reduces formation of alpha-synuclein aggregates in a rat model of nigral synucleinopathy. bioRxiv : the preprint server for biology. 2024-04-02. PMID:38562842. |
cannabinoid receptor-2 (cb2) is highly expressed on activated microglia and peripheral immune cells, is upregulated in the substantia nigra of individuals with pd and in mouse models of nigral degeneration. |
2024-04-02 |
2024-04-04 |
mouse |
| Ruohan Shan, Yuxiang Zhang, Yiping Shi, Xiaowen Wang, Xueke Wang, Guanying Ma, Qian L. Activation of Cannabinoid Type 2 Receptor in Microglia Reduces Neuroinflammation through Inhibiting Aerobic Glycolysis to Relieve Hypertension. Biomolecules. vol 14. issue 3. 2024-03-28. PMID:38540753. |
activation of cannabinoid type 2 receptor in microglia reduces neuroinflammation through inhibiting aerobic glycolysis to relieve hypertension. |
2024-03-28 |
2024-03-30 |
rat |
| Yue Chen, Yan Qin, Ying Gao, Saiying Wang, Qinhui Wang, Xiuling Tang, Zheng Rong, Caiyan Cheng, Longfei Li, Yuan Xu, Qi Yang, Yuping Tang, Minggao Zhao, Le Yan. Linderane Attenuates Complete Freund's Adjuvant-Induced Pain and Anxiety in Mice by Restoring Anterior Cingulate Cortex Microglia M2 Polarization through Activating Cannabinoid 2 Receptor. ACS pharmacology & translational science. vol 7. issue 3. 2024-03-14. PMID:38481693. |
linderane attenuates complete freund's adjuvant-induced pain and anxiety in mice by restoring anterior cingulate cortex microglia m2 polarization through activating cannabinoid 2 receptor. |
2024-03-14 |
2024-03-16 |
mouse |
| Rebecca Ferrisi, Francesca Gado, Caterina Ricardi, Beatrice Polini, Clementina Manera, Grazia Chiellin. The Interplay between Cannabinoid Receptors and Microglia in the Pathophysiology of Alzheimer's Disease. Journal of clinical medicine. vol 12. issue 23. 2023-12-09. PMID:38068253. |
the interplay between cannabinoid receptors and microglia in the pathophysiology of alzheimer's disease. |
2023-12-09 |
2023-12-17 |
Not clear |
| Maurício Dos Santos Pereira, Bruna Maitan Santos, Rocio Gimenez, Francisco Silveira Guimarães, Rita Raisman-Vozari, Elaine Del Bel, Patrick Pierre Miche. The two synthetic cannabinoid compounds 4'-F-CBD and HU-910 efficiently restrain inflammatory responses of brain microglia and astrocytes. Glia. 2023-11-28. PMID:38013496. |
the two synthetic cannabinoid compounds 4'-f-cbd and hu-910 efficiently restrain inflammatory responses of brain microglia and astrocytes. |
2023-11-28 |
2023-11-29 |
mouse |
| Sofia Papadogkonaki, Dimitris Spyridakos, Emmanouela Lapokonstantaki, Nikos Chaniotakis, Alexandros Makriyannis, Michael S Malamas, Kyriaki Thermo. Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958673. |
investigating the effects of exogenous and endogenous 2-arachidonoylglycerol on retinal cb1 cannabinoid receptors and reactive microglia in naive and diseased retina. |
2023-11-14 |
2023-11-20 |
rat |
| Sofia Papadogkonaki, Dimitris Spyridakos, Emmanouela Lapokonstantaki, Nikos Chaniotakis, Alexandros Makriyannis, Michael S Malamas, Kyriaki Thermo. Investigating the Effects of Exogenous and Endogenous 2-Arachidonoylglycerol on Retinal CB1 Cannabinoid Receptors and Reactive Microglia in Naive and Diseased Retina. International journal of molecular sciences. vol 24. issue 21. 2023-11-14. PMID:37958673. |
the endocannabinoid 2-arachidonoylglycerol (2-ag) affects neurons and microglia by activating cb1/cb2 cannabinoid receptors (rs). |
2023-11-14 |
2023-11-20 |
rat |
| Sara Standoli, Cinzia Rapino, Camilla Di Meo, Agnes Rudowski, Nicole Kämpfer-Kolb, Luisa Michelle Volk, Dominique Thomas, Sandra Trautmann, Yannick Schreiber, Dagmar Meyer Zu Heringdorf, Mauro Maccarron. Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37239854. |
sphingosine kinases at the intersection of pro-inflammatory lps and anti-inflammatory endocannabinoid signaling in bv2 mouse microglia cells. |
2023-05-27 |
2023-08-14 |
mouse |
| Sara Standoli, Cinzia Rapino, Camilla Di Meo, Agnes Rudowski, Nicole Kämpfer-Kolb, Luisa Michelle Volk, Dominique Thomas, Sandra Trautmann, Yannick Schreiber, Dagmar Meyer Zu Heringdorf, Mauro Maccarron. Sphingosine Kinases at the Intersection of Pro-Inflammatory LPS and Anti-Inflammatory Endocannabinoid Signaling in BV2 Mouse Microglia Cells. International journal of molecular sciences. vol 24. issue 10. 2023-05-27. PMID:37239854. |
in this context, components of the endocannabinoid (ecb) system have been shown to shift microglia towards an anti-inflammatory activation state. |
2023-05-27 |
2023-08-14 |
mouse |
| Berhanu Geresu Kibret, Aaliyah Roberts, Adam Kneebone, Shymaa Embaby, Justin Fernandez, Qing-Rong Liu, Emmanuel S Onaiv. Cannabinoid CB2 receptors modulate alcohol induced behavior, and neuro-immune dysregulation in mice. Behavioural brain research. 2023-04-15. PMID:37061199. |
we investigated the role of cannabinoid type 2 receptors (cb2rs) in modulating behavioral and neuro-immune changes induced by alcohol using conditional knockout (cko) mice with selective deletion of cb2rs in dopamine neurons (dat-cnr2) and in microglia (cx3cr1-cnr2) cko mice. |
2023-04-15 |
2023-08-14 |
mouse |
| Brittney R Lins, Chidozie C Anyaegbu, Sarah C Hellewell, Melissa Papini, Terence McGonigle, Luca De Prato, Matthew Shales, Melinda Fitzgeral. Cannabinoids in traumatic brain injury and related neuropathologies: preclinical and clinical research on endogenous, plant-derived, and synthetic compounds. Journal of neuroinflammation. vol 20. issue 1. 2023-03-20. PMID:36935484. |
cannabinoids interact with neurons, microglia, and astrocytes, and exert anti-inflammatory and neuroprotective effects which are highly desirable for the management of traumatic brain injury. |
2023-03-20 |
2023-08-14 |
Not clear |
| Yanxia Guo, Min Yan, Li Li, Li Zhao, Yan L. Treadmill Exercise Prevents Cognitive Impairments in Adolescent Intermittent Ethanol Rats by Reducing the Excessive Activation of Microglia Cell in the Hippocampus. International journal of molecular sciences. vol 23. issue 23. 2022-12-11. PMID:36499029. |
the endocannabinoid system plays a key role in the modulation of microglia activation. |
2022-12-11 |
2023-08-14 |
rat |
| Sara Marinelli, Maria Cristina Marrone, Marina Di Domenico, Silvia Marinell. Endocannabinoid signaling in microglia. Glia. 2022-10-12. PMID:36222019. |
endocannabinoid signaling in microglia. |
2022-10-12 |
2023-08-14 |
mouse |
| Sara Marinelli, Maria Cristina Marrone, Marina Di Domenico, Silvia Marinell. Endocannabinoid signaling in microglia. Glia. 2022-10-12. PMID:36222019. |
among signals controlling microglia activity, the endocannabinoid (ec) system has been shown to exert a neuroprotective role in many neurological diseases. |
2022-10-12 |
2023-08-14 |
mouse |
| Alexander P Young, Eileen M Denovan-Wrigh. The microglial endocannabinoid system is similarly regulated by lipopolysaccharide and interferon gamma. Journal of neuroimmunology. vol 372. 2022-09-23. PMID:36150252. |
microglia are one of few cell types with a self-contained endocannabinoid system and are positioned at the interface between the immune system and the central nervous system. |
2022-09-23 |
2023-08-14 |
Not clear |
| Alexander P Young, Eileen M Denovan-Wrigh. The microglial endocannabinoid system is similarly regulated by lipopolysaccharide and interferon gamma. Journal of neuroimmunology. vol 372. 2022-09-23. PMID:36150252. |
thus, we systematically investigated the relationship between the concentration of two distinct pro-inflammatory stimuli, lipopolysaccharide and interferon gamma, on the abundance of components of the endocannabinoid system within microglia. |
2022-09-23 |
2023-08-14 |
Not clear |
| Alexander P Young, Eileen M Denovan-Wrigh. The microglial endocannabinoid system is similarly regulated by lipopolysaccharide and interferon gamma. Journal of neuroimmunology. vol 372. 2022-09-23. PMID:36150252. |
furthermore, we demonstrate that the efficacy of different synthetic cannabinoid treatments with respect to inhibition of microglia nitric oxide release is dependent on the concentration and type of pro-inflammatory stimuli presented to the microglia. |
2022-09-23 |
2023-08-14 |
Not clear |
| Alexander P Young, Eileen M Denovan-Wrigh. The microglial endocannabinoid system is similarly regulated by lipopolysaccharide and interferon gamma. Journal of neuroimmunology. vol 372. 2022-09-23. PMID:36150252. |
this indicates that different pro-inflammatory stimuli influence the capacity of microglia to synthesize, degrade, and respond to cannabinoids which has implications for the development of cannabinoid-based treatments for neuroinflammation. |
2022-09-23 |
2023-08-14 |
Not clear |
| Alberto Llorente-Ovejero, Iker Bengoetxea de Tena, Jonatan Martínez-Gardeazabal, Marta Moreno-Rodríguez, Laura Lombardero, Iván Manuel, Rafael Rodríguez-Puerta. Cannabinoid Receptors and Glial Response Following a Basal Forebrain Cholinergic Lesion. ACS pharmacology & translational science. vol 5. issue 9. 2022-09-16. PMID:36110372. |
using autoradiographic studies, the density and functional coupling to g-proteins of endocannabinoid receptor subtypes were studied in tissue sections from different brain areas where microglia density increased, using cb |
2022-09-16 |
2023-08-14 |
rat |
| Alexander P Young, Eileen M Denovan-Wrigh. Synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro. Brain, behavior, and immunity. 2022-06-28. PMID:35764268. |
synthetic cannabinoids reduce the inflammatory activity of microglia and subsequently improve neuronal survival in vitro. |
2022-06-28 |
2023-08-14 |
Not clear |