| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chi Young Chang, Dong-Kug Choi, Dae Kee Lee, Young Jun Hong, Eun Jung Par. Resveratrol confers protection against rotenone-induced neurotoxicity by modulating myeloperoxidase levels in glial cells. PloS one. vol 8. issue 4. 2013-11-05. PMID:23593274. |
we show that resveratrol significantly reduced mpo levels but did not trigger abnormal nitric oxide (no) production in microglia and astrocytes. |
2013-11-05 |
2023-08-12 |
mouse |
| Karim Arafah, Dominique Croix, Jacopo Vizioli, Annie Desmons, Isabelle Fournier, Michel Salze. Involvement of nitric oxide through endocannabinoids release in microglia activation during the course of CNS regeneration in the medicinal leech. Glia. vol 61. issue 4. 2013-10-28. PMID:23355252. |
involvement of nitric oxide through endocannabinoids release in microglia activation during the course of cns regeneration in the medicinal leech. |
2013-10-28 |
2023-08-12 |
Not clear |
| Ping Liu, Yong-Sheng Li, David Quartermain, Allal Boutajangout, Yong J. Inhaled nitric oxide improves short term memory and reduces the inflammatory reaction in a mouse model of mild traumatic brain injury. Brain research. vol 1522. 2013-10-23. PMID:23743262. |
in the present study, mtbi was induced by a weight drop model to produce a closed head injury to mice and the effect of inhaled nitric oxide (ino) was evaluated by a short term memory task (object recognition task) and immunohistochemical staining of glial fibrillary acidic protein (gfap) and cd45 for the detection of reactive astrocytes and microglia. |
2013-10-23 |
2023-08-12 |
mouse |
| Juan Li, Jing Yu Yang, Xue Chun Yao, Xue Xue, Qing Chun Zhang, Xiao Xiao Wang, Ling Ling Ding, Chun Fu W. Oligomeric Aβ-induced microglial activation is possibly mediated by NADPH oxidase. Neurochemical research. vol 38. issue 2. 2013-10-17. PMID:23229789. |
the results showed that oaβ induced activated properties of microglia, including higher proliferative capacity as well as increased production of reactive oxygen species, nitric oxide (no), tumor necrosis factor-α (tnf-α), and interleukin-1β (il-1β). |
2013-10-17 |
2023-08-12 |
Not clear |
| Seung Young Lee, Eunjung Moon, Sun Yeou Kim, Kang Ro Le. Quinic acid derivatives from Pimpinella brachycarpa exert anti-neuroinflammatory activity in lipopolysaccharide-induced microglia. Bioorganic & medicinal chemistry letters. vol 23. issue 7. 2013-09-30. PMID:23462643. |
isolated compounds 1-15 were evaluated for their inhibitory activities on nitric oxide (no) production in an activated murine microglial cell line. |
2013-09-30 |
2023-08-12 |
Not clear |
| Xiaohui Wang, Peter M Grace, Michael N Pham, Kui Cheng, Keith A Strand, Christina Smith, Jing Li, Linda R Watkins, Hang Yi. Rifampin inhibits Toll-like receptor 4 signaling by targeting myeloid differentiation protein 2 and attenuates neuropathic pain. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 27. issue 7. 2013-09-18. PMID:23568774. |
rifampin blocked tlr4 signaling induced by lps, including nf-κb activation and the overproduction of proinflammatory mediators nitric oxide, interleukin 1β, and tumor necrosis factor α in mouse microglia bv-2 cells and macrophage raw 264.7 cells. |
2013-09-18 |
2023-08-12 |
mouse |
| Hui Li, Baoyi Liu, Jingyang Huang, Haili Chen, Xiaosun Guo, Zhongrui Yua. Insulin inhibits lipopolysaccharide-induced nitric oxide synthase expression in rat primary astrocytes. Brain research. vol 1506. 2013-09-13. PMID:23416152. |
excessive production of nitric oxide (no) by inducible nitric oxide synthase (inos) from reactive astrocytes and microglia may contribute to the development of many types of neurological diseases. |
2013-09-13 |
2023-08-12 |
rat |
| Hwan-Suck Chung, Sae-Noon Kim, Jin-Hyun Jeong, Hyunsu Ba. A novel synthetic compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells. Neurochemical research. vol 38. issue 4. 2013-09-12. PMID:23377856. |
a novel synthetic compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines via the nf-κb pathway in lipopolysaccharide-activated microglia cells. |
2013-09-12 |
2023-08-12 |
mouse |
| Hwan-Suck Chung, Sae-Noon Kim, Jin-Hyun Jeong, Hyunsu Ba. A novel synthetic compound 4-acetyl-3-methyl-6-(2-bromophenyl)pyrano[3,4-c]pyran-1,8-dione inhibits the production of nitric oxide and proinflammatory cytokines via the NF-κB pathway in lipopolysaccharide-activated microglia cells. Neurochemical research. vol 38. issue 4. 2013-09-12. PMID:23377856. |
ppy-br suppresses nitric oxide production, inducible nitric oxide synthase expression, and tumor necrosis factor-α and interleukin-6 production in lps-activated bv-2 microglial cell line and mouse primary microglia. |
2013-09-12 |
2023-08-12 |
mouse |
| Su-Chen Ho, Ku-Shang Chang, Pei-Wen Chan. Inhibition of neuroinflammation by cinnamon and its main components. Food chemistry. vol 138. issue 4. 2013-09-04. PMID:23497886. |
in total, 50 μg/ml cinnamon extract decreased significantly the production and expression of nitric oxide (no), interleukin (il)-1β, il-6, and tumor necrosis factor (tnf)-α in lps-activated bv2 microglia. |
2013-09-04 |
2023-08-12 |
Not clear |
| Byung-Wook Kim, Sushruta Koppula, Seong-Su Hong, Sae-Bom Jeon, Ji-Hye Kwon, Bang-Yeon Hwang, Eun-Jung Park, Dong-Kug Cho. Regulation of microglia activity by glaucocalyxin-A: attenuation of lipopolysaccharide-stimulated neuroinflammation through NF-κB and p38 MAPK signaling pathways. PloS one. vol 8. issue 2. 2013-08-26. PMID:23393601. |
gla significantly inhibited lps-induced production of nitric oxide and reversed the morphological changes in primary microglia. |
2013-08-26 |
2023-08-12 |
Not clear |
| A-Reum Kim, Min-Sup Lee, Ji-Woong Choi, Tadanobu Utsuki, Jae-Il Kim, Byeong-Churl Jang, Hyeung-Rak Ki. Phlorofucofuroeckol A suppresses expression of inducible nitric oxide synthase, cyclooxygenase-2, and pro-inflammatory cytokines via inhibition of nuclear factor-κB, c-Jun NH2-terminal kinases, and Akt in microglial cells. Inflammation. vol 36. issue 2. 2013-08-23. PMID:22993079. |
pre-treatment of phlorofucofuroeckol a attenuated the productions of nitric oxide, prostaglandin e2, and pro-inflammatory cytokines in lps-stimulated microglia. |
2013-08-23 |
2023-08-12 |
Not clear |
| Chang-Hee Kang, Rajapaksha Gendara Prasad Tharanga Jayasooriya, Yung Hyun Choi, Sung-Kwon Moon, Wun-Jae Kim, Gi-Young Ki. β-Ionone attenuates LPS-induced pro-inflammatory mediators such as NO, PGE2 and TNF-α in BV2 microglial cells via suppression of the NF-κB and MAPK pathway. Toxicology in vitro : an international journal published in association with BIBRA. vol 27. issue 2. 2013-08-20. PMID:23268108. |
in this study, we investigated whether ion attenuates the expression of lipopolysaccharide (lps)-induced pro-inflammatory mediators such as nitric oxide (no), prostaglandin e2 (pge2) and tumor necrosis factor-α (tnf-α) in bv2 microglia cells. |
2013-08-20 |
2023-08-12 |
Not clear |
| Ki Hyun Kim, Eunjung Moon, Sang Un Choi, Sun Yeou Kim, Kang Ro Le. Lanostane triterpenoids from the mushroom Naematoloma fasciculare. Journal of natural products. vol 76. issue 5. 2013-08-20. PMID:23634786. |
compounds 1-15 were tested for their antiproliferative activities against four human cancer cell lines (a549, sk-ov-3, sk-mel-2, and hct-15) and evaluated for their inhibitory effects on nitric oxide production in a lipopolysaccharide-activated murine microglial cell line. |
2013-08-20 |
2023-08-12 |
human |
| Seung Young Lee, Eunjung Moon, Sun Yeou Kim, Sang Un Choi, Kang Ro Le. Quinone derivatives from the rhizomes of Acorus gramineus and their biological activities. Bioscience, biotechnology, and biochemistry. vol 77. issue 2. 2013-08-14. PMID:23439566. |
to investigate the anti-neuroinflammatory effects of the isolated compounds (1-5), the nitric oxide (no) production was evaluated in the lipopolysaccharide-activated microglia cell line, bv-2. |
2013-08-14 |
2023-08-12 |
human |
| Amalia M Dolga, Till Letsche, Maike Gold, Nunzianna Doti, Michael Bacher, Nipavan Chiamvimonvat, Richard Dodel, Carsten Culmse. Activation of KCNN3/SK3/K(Ca)2.3 channels attenuates enhanced calcium influx and inflammatory cytokine production in activated microglia. Glia. vol 60. issue 12. 2013-08-05. PMID:23002008. |
furthermore, cyppa reduced downstream events including tumor necrosis factor alpha and interleukin 6 cytokine production and nitric oxide release in activated microglia. |
2013-08-05 |
2023-08-12 |
mouse |
| Vadivel Parthsarathy, Christian Hölsche. The type 2 diabetes drug liraglutide reduces chronic inflammation induced by irradiation in the mouse brain. European journal of pharmacology. vol 700. issue 1-3. 2013-08-05. PMID:23276669. |
brains were analysed for cytokine levels, activated microglia and astrocyte levels, and nitrite levels as a measure for nitric oxide production and protein expression of inos. |
2013-08-05 |
2023-08-12 |
mouse |
| Kang-Woo Lee, Joo-Young Im, Jong-Min Woo, Hilary Grosso, Yoon-Seong Kim, Ana Clara Cristovao, Patricia K Sonsalla, David S Schuster, Marla M Jalbut, Jose R Fernandez, Michael Voronkov, Eunsung Junn, Steven P Braithwaite, Jeffry B Stock, M Maral Mouradia. Neuroprotective and anti-inflammatory properties of a coffee component in the MPTP model of Parkinson's disease. Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics. vol 10. issue 1. 2013-07-29. PMID:23296837. |
in cultured primary microglia and astrocytes, eht had a direct anti-inflammatory effect demonstrated by repression of lipopolysaccharide-induced nfκb activation, inos induction, and nitric oxide production. |
2013-07-29 |
2023-08-12 |
mouse |
| Youngpyo Nam, Mijung Choi, Heehong Hwang, Maan-Gee Lee, Byoung-Mog Kwon, Won-Ha Lee, Kyoungho Su. Natural flavone jaceosidin is a neuroinflammation inhibitor. Phytotherapy research : PTR. vol 27. issue 3. 2013-06-27. PMID:22619052. |
we report that jaceosidin inhibits inflammatory activation of microglia, reducing nitric oxide (no) production and proinflammatory cytokine expression. |
2013-06-27 |
2023-08-12 |
mouse |
| Susanne Höing, York Rudhard, Peter Reinhardt, Michael Glatza, Martin Stehling, Guangming Wu, Christiane Peiker, Alexander Böcker, Juan A Parga, Eva Bunk, Jens C Schwamborn, Mark Slack, Jared Sterneckert, Hans R Schöle. Discovery of inhibitors of microglial neurotoxicity acting through multiple mechanisms using a stem-cell-based phenotypic assay. Cell stem cell. vol 11. issue 5. 2013-06-27. PMID:23064101. |
these compounds act through diverse pathways, including the inhibition of nitric oxide production by microglia, activation of the nrf2 pathway in microglia and astrocytes, and direct protection of neurons from nitric-oxide-induced degeneration. |
2013-06-27 |
2023-08-12 |
human |