All Relations between microglial cell and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Y Mizoguchi, A Monji, T A Kato, H Horikawa, Y Seki, M Kasai, S Kanba, S Yamad. Possible role of BDNF-induced microglial intracellular Ca(2+) elevation in the pathophysiology of neuropsychiatric disorders. Mini reviews in medicinal chemistry. vol 11. issue 7. 2011-10-06. PMID:21699488. microglia are intrinsic immune cells that release factors, including proinflammatory cytokines, nitric oxide (no) and neurotrophins, following activation after disturbance in the brain. 2011-10-06 2023-08-12 Not clear
Jie Wen, Rachel Ribeiro, Yumin Zhan. Specific PKC isoforms regulate LPS-stimulated iNOS induction in murine microglial cells. Journal of neuroinflammation. vol 8. 2011-10-03. PMID:21510893. excessive production of nitric oxide (no) by inducible nitric oxide synthase (inos) in reactive microglia is a major contributor to initiation/exacerbation of inflammatory and degenerative neurological diseases. 2011-10-03 2023-08-12 Not clear
Hye Young Park, Min Ho Han, Cheol Park, Cheng-Yun Jin, Gi-Young Kim, Il-Whan Choi, Nam Deuk Kim, Taek-Jeong Nam, Taeg Kyu Kwon, Yung Hyun Cho. Anti-inflammatory effects of fucoidan through inhibition of NF-κB, MAPK and Akt activation in lipopolysaccharide-induced BV2 microglia cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 8. 2011-09-26. PMID:21570441. our data indicated that fucoidan treatment significantly inhibited excessive production of nitric oxide (no) and prostaglandin e₂ (pge₂) in lps-stimulated bv2 microglia. 2011-09-26 2023-08-12 Not clear
S Wang, H Wang, H Guo, L Kang, X Gao, L H. Neuroprotection of Scutellarin is mediated by inhibition of microglial inflammatory activation. Neuroscience. vol 185. 2011-09-19. PMID:21524691. we observed that scutellarin inhibited lipopolysaccharide (lps)-induced production of proinflammatory mediators such as nitric oxide (no), tumor necrosis factor α (tnfα), interleukin-1β (il-1β) and reactive oxygen species (ros), suppressed lps-stimulated inducible nitric oxide synthase (inos), tnfα, and il-1β mrna expression in rat primary microglia or bv-2 mouse microglial cell line. 2011-09-19 2023-08-12 mouse
Elizabeth Gray, Mark Ginty, Kevin Kemp, Neil Scolding, Alastair Wilkin. Peroxisome proliferator-activated receptor-α agonists protect cortical neurons from inflammatory mediators and improve peroxisomal function. The European journal of neuroscience. vol 33. issue 8. 2011-09-16. PMID:21375604. to assess the influence of peroxisomal activation on nitric oxide-mediated neurotoxicity, we investigated the effects of the peroxisomal proliferator-activated receptor (ppar)-α agonist fenofibrate on cortical neurons exposed to a nitric oxide donor or co-cultured with activated microglia. 2011-09-16 2023-08-12 Not clear
Richa Sachdeva, Rashmi Babbar, Vinod Puri, Sarita Agarwal, Bal Krishan. Correlation between cognitive functions and nitric oxide levels in patients with dementia. Clinical EEG and neuroscience. vol 42. issue 3. 2011-09-15. PMID:21870472. at high levels, nitric oxide (no), which is produced by microglia due to induction of nitric oxide synthase (nos), is neurotoxic and may play a role in neurodegeneration. 2011-09-15 2023-08-12 human
Yingqian Huo, Parakalan Rangarajan, Eng-Ang Ling, S Thameem Dhee. Dexamethasone inhibits the Nox-dependent ROS production via suppression of MKP-1-dependent MAPK pathways in activated microglia. BMC neuroscience. vol 12. 2011-09-12. PMID:21615929. nox-dependent ros generation and nitric oxide (no) release by microglia have been implicated in a variety of diseases in the central nervous system. 2011-09-12 2023-08-12 Not clear
Eun Ju Jeong, Heejung Yang, Seung Hyun Kim, So Young Kang, Sang Hyun Sung, Young Choong Ki. Inhibitory constituents of Euonymus alatus leaves and twigs on nitric oxide production in BV2 microglia cells. Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association. vol 49. issue 6. 2011-08-30. PMID:21426922. inhibitory constituents of euonymus alatus leaves and twigs on nitric oxide production in bv2 microglia cells. 2011-08-30 2023-08-12 Not clear
Feng Huang, Hua-Ming Deng, Miao-Miao Zhu, Fei Xiao, Li Yang, Zai-Jun Zhang, Ying Xiao, Hong Ni. [Inhibitory effect of ferulic acid on inflammatory response in microglia induced by lipopolysaccharides]. Dong wu xue yan jiu = Zoological research. vol 32. issue 3. 2011-08-25. PMID:21698798. our study showed that fa significantly suppressed the production of nitric oxide (no), prostaglandin e2 (pge2), interleukin-1β (il-1β), and decreased induced type ii nitric oxide synthase (inos) and cyclooxygenase-2 (cox-2) protein in lps-stimulated bv-2 microglia cells in a dose dependent manner. 2011-08-25 2023-08-12 Not clear
Hironobu Eguchi, Noriko Fujiwara, Haruhiko Sakiyama, Daisaku Yoshihara, Keiichiro Suzuk. Hydrogen peroxide enhances LPS-induced nitric oxide production via the expression of interferon beta in BV-2 microglial cells. Neuroscience letters. vol 494. issue 1. 2011-08-15. PMID:21354265. activated microglia produces inflammatory cytokines and nitric oxide (no) that involved in neuronal injury and neurodegenerative diseases. 2011-08-15 2023-08-12 Not clear
Ki Hyun Kim, Jung Wook Choi, Sang Un Choi, Sang Keun Ha, Sun Yeou Kim, Hee-Juhn Park, Kang Ro Le. The chemical constituents of Piper kadsura and their cytotoxic and anti-neuroinflammtaory activities. Journal of enzyme inhibition and medicinal chemistry. vol 26. issue 2. 2011-07-26. PMID:20687793. the n-hexane and chcl₃ soluble fractions of the meoh extract of the aerial parts of piper kadsura were found to potently inhibit nitric oxide (no) production in lps-activated bv-2 cells, a microglial cell line. 2011-07-26 2023-08-12 human
Ki Hyun Kim, Jung Wook Choi, Sang Un Choi, Sang Keun Ha, Sun Yeou Kim, Hee-Juhn Park, Kang Ro Le. The chemical constituents of Piper kadsura and their cytotoxic and anti-neuroinflammtaory activities. Journal of enzyme inhibition and medicinal chemistry. vol 26. issue 2. 2011-07-26. PMID:20687793. compounds 2, 6, and 11-14 significantly inhibited both nitric oxide (no) and prostaglandin e₂ (pge₂) production in the lps-activated microglia cells. 2011-07-26 2023-08-12 human
Ki Hyun Kim, Eunjung Moon, Sang Un Choi, Sun Yeou Kim, Kang Ro Le. Biological evaluation of phenolic constituents from the trunk of Berberis koreana. Bioorganic & medicinal chemistry letters. vol 21. issue 8. 2011-07-19. PMID:21420296. in addition, compounds 3-8 and 15 strongly reduced nitric oxide (no) production in lipopolysaccharide (lps)-activated bv-2 cells, a microglial cell line. 2011-07-19 2023-08-12 Not clear
Emily C Brantley, Lixia Guo, Chenyu Zhang, Qingtang Lin, Kenji Yokoi, Robert R Langley, Ewa Kruzel, Marva Maya, Seung Wook Kim, Sun-Jin Kim, Dominic Fan, Isaiah J Fidle. Nitric oxide-mediated tumoricidal activity of murine microglial cells. Translational oncology. vol 3. issue 6. 2011-07-14. PMID:21151477. control microglia were not tumoricidal against a number of murine and human tumor cells, whereas lipopolysaccharide/interferon-γ-activated microglia lysed murine and human tumor cells by release of nitric oxide. 2011-07-14 2023-08-12 mouse
Dawn Béraud, Margaret Twomey, Benjamin Bloom, Andrew Mittereder, Vy Ton, Katherine Neitzke, Sergey Chasovskikh, Timothy R Mhyre, Kathleen A Maguire-Zeis. α-Synuclein Alters Toll-Like Receptor Expression. Frontiers in neuroscience. vol 5. 2011-07-14. PMID:21747756. upon proinflammatory pathway initiation, activated microglia contribute to oxidative stress through release of cytokines, nitric oxide, and other reactive oxygen species, which may adversely impact adjacent neurons. 2011-07-14 2023-08-12 mouse
Terry C T Or, Cindy L H Yang, Anna H Y Law, James C B Li, Allan S Y La. Isolation and identification of anti-inflammatory constituents from Ligusticum chuanxiong and their underlying mechanisms of action on microglia. Neuropharmacology. vol 60. issue 6. 2011-07-12. PMID:21146552. during ischemia, inflammatory mediators including tumor necrosis factor-alpha (tnf-α) and nitric oxide are produced by microglia, which play a central role in the pathogenesis of the disease. 2011-07-12 2023-08-12 human
Madhuvika Murugan, Viswanathan Sivakumar, Jia Lu, Eng-Ang Ling, Charanjit Kau. Expression of N-methyl D-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF-κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats. Glia. vol 59. issue 4. 2011-06-30. PMID:21319220. expression of n-methyl d-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via nf-κb signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats. 2011-06-30 2023-08-12 rat
Madhuvika Murugan, Viswanathan Sivakumar, Jia Lu, Eng-Ang Ling, Charanjit Kau. Expression of N-methyl D-aspartate receptor subunits in amoeboid microglia mediates production of nitric oxide via NF-κB signaling pathway and oligodendrocyte cell death in hypoxic postnatal rats. Glia. vol 59. issue 4. 2011-06-30. PMID:21319220. mk801 also down regulated the hypoxia-induced expression of tumor necrosis factor-α, interleukin-1β, inducible nitric oxide synthase (inos), and nitric oxide (no) production by microglia which may be mediated by the nf-κb signaling pathway. 2011-06-30 2023-08-12 rat
Yanji Cui, Jinji Wu, Sung-Cherl Jung, Deok-Bae Park, Young-Hee Maeng, Jeong Yun Hong, Se-Jae Kim, Sun-Ryung Lee, Soon-Jong Kim, Sang Jeong Kim, Su-Yong Eu. Anti-neuroinflammatory activity of nobiletin on suppression of microglial activation. Biological & pharmaceutical bulletin. vol 33. issue 11. 2011-06-29. PMID:21048305. release of nitric oxide (no), the major inflammatory mediator in microglia, was markedly suppressed in a dose-dependent manner following nobiletin treatment (1-50 µm) in lps-stimulated bv-2 microglia cells. 2011-06-29 2023-08-12 Not clear
Susumu Kohno, Tomiyasu Murata, Ayumi Sugiura, Chihiro Ito, Mehrdad Iranshahi, Kiyomi Hikita, Norio Kaned. Methyl galbanate, a novel inhibitor of nitric oxide production in mouse macrophage RAW264.7 cells. Journal of natural medicines. vol 65. issue 2. 2011-06-23. PMID:21246298. an inflammatory mediator, nitric oxide (no), is produced by inducible no synthase (inos) in microglia and seems to be one of the possible causes of neurodegeneration. 2011-06-23 2023-08-12 mouse