All Relations between microglial cell and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Xuesen Yang, Genlin He, Yutong Hao, Chunhai Chen, Maoquan Li, Yuan Wang, Guangbin Zhang, Zhengping Y. The role of the JAK2-STAT3 pathway in pro-inflammatory responses of EMF-stimulated N9 microglial cells. Journal of neuroinflammation. vol 7. 2010-12-06. PMID:20828402. our previous studies have shown that exposure to electromagnetic fields (emf) activates cultured microglia to produce tumor necrosis factor (tnf)-α and nitric oxide (no) through signal transduction involving the activator of transcription stat3. 2010-12-06 2023-08-12 Not clear
Ya-Fang He, Hui-Jin Chen, Long-Hua Qian, Guan-Yi Che. [Effect of 1400W, an inhibitor of inducible nitric oxide synthetase, on blocking the toxicity of lipopolysaccharide-induced activated microglia to preoligodendrocytes]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 47. issue 7. 2010-12-02. PMID:19951519. [effect of 1400w, an inhibitor of inducible nitric oxide synthetase, on blocking the toxicity of lipopolysaccharide-induced activated microglia to preoligodendrocytes]. 2010-12-02 2023-08-12 Not clear
Ya-Fang He, Hui-Jin Chen, Long-Hua Qian, Guan-Yi Che. [Effect of 1400W, an inhibitor of inducible nitric oxide synthetase, on blocking the toxicity of lipopolysaccharide-induced activated microglia to preoligodendrocytes]. Zhonghua er ke za zhi = Chinese journal of pediatrics. vol 47. issue 7. 2010-12-02. PMID:19951519. to explore the toxicity of lps-induced activated microglia to preoligodendrocytes (preols) and the effect of 1400w, a selective inhibitor of inducible nitric oxide synthetase (inos), on the blockage of the toxicity. 2010-12-02 2023-08-12 Not clear
Eun-A Kim, Hanwook Kim, Jee-Yin Ahn, Hoh-Gyu Hahn, Key-Sun Kim, Tae Ue Kim, Sung-Woo Ch. Suppression of lipopolysaccharide-induced microglial activation by a benzothiazole derivative. Molecules and cells. vol 30. issue 1. 2010-11-22. PMID:20652495. specifically, khg21834 induces significant reductions in the lipopolysaccharide-induced activation of microglia and production of proinflammatory mediators such as tumor necrosis factor-alpha, interlukin-1beta, nitric oxide, and inducible nitric oxide synthase. 2010-11-22 2023-08-12 Not clear
Heehong Hwang, Shinrye Lee, Won-Ha Lee, Ho-Jae Lee, Kyoungho Su. Stimulation of glucocorticoid-induced tumor necrosis factor receptor family-related protein ligand (GITRL) induces inflammatory activation of microglia in culture. Journal of neuroscience research. vol 88. issue 10. 2010-10-26. PMID:20162721. using bv-2 mouse microglia cells and mouse primary microglia cultures, we have demonstrated that 1) both gitr and gitrl are expressed in microglia cells; 2) stimulation of gitrl induces inflammatory activation of microglia on the basis of production of nitric oxide (no) and expression of inducible nitric oxide synthase, cyclooxygenase-2, cd40, and matrix metalloproteinase-9; 3) gitrl-mediated microglial no production partially depends on p38 mapk, jnk, and nuclear factor-kappab pathways; and 4) gitrl stimulation also induces microglia cell death. 2010-10-26 2023-08-12 mouse
Jing Ding, Qin-Ying Li, Xin Wang, Chang-Hai Sun, Chuan-Zhen Lu, Bao-Guo Xia. Fasudil protects hippocampal neurons against hypoxia-reoxygenation injury by suppressing microglial inflammatory responses in mice. Journal of neurochemistry. vol 114. issue 6. 2010-10-19. PMID:20882700. further immunohistochemical analysis and cytokine determination revealed that fasudil inhibited inducible nitric oxide synthase immunoreactivity in microglia and pro-inflammatory factors in brain tissue after h/r, which is consistent with the observation wherein fasudil reduced the pro-inflammatory factors nitric oxide, il-1β, il-6 and tnf-, and increased anti-inflammatory factor il-10 in cultured microglia under normoxic or hypoxic conditions. 2010-10-19 2023-08-12 mouse
Yasuhiro Yoshioka, Nobuo Takeda, Akiko Yamamuro, Atsushi Kasai, Sadaaki Maed. Nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cGMP signaling pathway in murine microglia BV-2 cells. Journal of pharmacological sciences. vol 113. issue 2. 2010-09-23. PMID:20484865. nitric oxide inhibits lipopolysaccharide-induced inducible nitric oxide synthase expression and its own production through the cgmp signaling pathway in murine microglia bv-2 cells. 2010-09-23 2023-08-12 Not clear
Jiyeon Ock, Su Hyung Hong, Kyoungho Su. Identification of KT-15073 as an inhibitor of lipopolysaccharide-induced microglial activation. Biological & pharmaceutical bulletin. vol 33. issue 3. 2010-09-20. PMID:20190410. activated microglia produce various proinflammatory cytokines and nitric oxide (no) that are toxic to neurons. 2010-09-20 2023-08-12 Not clear
Bin Xing, Tao Xin, Lingling Zhao, Randy L Hunter, Yan Chen, Guoying Bin. Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity. Journal of neuroimmunology. vol 225. issue 1-2. 2010-09-16. PMID:20471698. aberrant microglia activation causes dopaminergic neuronal loss and nitric oxide produced by microglia plays a critical role in dopaminergic neuronal degeneration. 2010-09-16 2023-08-12 Not clear
Bin Xing, Tao Xin, Lingling Zhao, Randy L Hunter, Yan Chen, Guoying Bin. Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity. Journal of neuroimmunology. vol 225. issue 1-2. 2010-09-16. PMID:20471698. we report that gdnf not only reduces lipopolysaccharide-induced degeneration of dopaminergic neurons, suppresses microglia activation and nitric oxide generation, but also reverses the inhibition of phosphoinositide 3-kinase (pi3k) in dopaminergic neurons and microglia. 2010-09-16 2023-08-12 Not clear
Bin Xing, Tao Xin, Lingling Zhao, Randy L Hunter, Yan Chen, Guoying Bin. Glial cell line-derived neurotrophic factor protects midbrain dopaminergic neurons against lipopolysaccharide neurotoxicity. Journal of neuroimmunology. vol 225. issue 1-2. 2010-09-16. PMID:20471698. it suggests that the neuroprotective effect of gdnf on dopaminergic neurons may be related to its suppression of microglia activation-mediated nitric oxide via releasing the inhibition of pi3k in both neurons and microglia. 2010-09-16 2023-08-12 Not clear
Eliza Hutter, Sebastien Boridy, Simon Labrecque, Melanie Lalancette-Hébert, Jasna Kriz, Françoise M Winnik, Dusica Maysinge. Microglial response to gold nanoparticles. ACS nano. vol 4. issue 5. 2010-09-07. PMID:20329742. analysis by dark-field microscopy and by two-photon-induced luminescence (tpl) indicates that the exposure of neural cells to gnps resulted in (i) gnp internalization by both microglial cells and primary hippocampal neurons, as revealed by dark-field microscopy and by two-photon-induced luminescence (tpl), (ii) transient toll-like receptor 2 (tlr-2) up-regulation in the olfactory bulb, after intranasal administration in transgenic mice, in vivo, in real time, and (iii) differential up-regulation in vitro of tlr-2 together with interleukin 1 alpha (il-1alpha), granulocyte macrophage colony-stimulating factor (gm-csf) and nitric oxide (no) in microglia. 2010-09-07 2023-08-12 mouse
Ke-Wu Zeng, Hong Fu, Geng-Xin Liu, Xue-Mei Wan. Icariin attenuates lipopolysaccharide-induced microglial activation and resultant death of neurons by inhibiting TAK1/IKK/NF-kappaB and JNK/p38 MAPK pathways. International immunopharmacology. vol 10. issue 6. 2010-09-03. PMID:20347053. here, we reported the discovery that icariin significantly inhibited the release of nitric oxide (no), prostaglandin e (pge)-2, reactive oxygen species (ros) and mrna expression of proinflammatory cytokines such as tumor necrosis factor (tnf)-alpha, interleukin (il)-1beta and il-6 in lipopolysaccharide (lps)-activated microglia. 2010-09-03 2023-08-12 Not clear
Payam Dibaj, Fabien Nadrigny, Heinz Steffens, Anja Scheller, Johannes Hirrlinger, Eike D Schomburg, Clemens Neusch, Frank Kirchhof. NO mediates microglial response to acute spinal cord injury under ATP control in vivo. Glia. vol 58. issue 9. 2010-08-26. PMID:20468054. by investigating acute lesions of spinal cord white matter in anesthetized mice with fluorescently labeled microglia and axons using in vivo two-photon laser-scanning microscopy (2p-lsm), we identified the messenger nitric oxide (no) as a modulator of injury-activated microglia. 2010-08-26 2023-08-12 mouse
Tomohiro Matsui, Camilla I Svensson, Yuka Hirata, Kanae Mizobata, Xiao-Ying Hua, Tony L Yaks. Release of prostaglandin E(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase. Anesthesia and analgesia. vol 111. issue 2. 2010-08-26. PMID:20610553. release of prostaglandin e(2) and nitric oxide from spinal microglia is dependent on activation of p38 mitogen-activated protein kinase. 2010-08-26 2023-08-12 rat
Shao-Xia Wang, Li-Min Hu, Xiu-Mei Gao, Hong Guo, Guan-Wei Fa. Anti-inflammatory activity of salvianolic acid B in microglia contributes to its neuroprotective effect. Neurochemical research. vol 35. issue 7. 2010-08-20. PMID:20238162. our results showed that sal b significantly reduced the production of nitric oxide (no), tumor necrosis factor-alpha (tnf-alpha), interleukin-1beta (il-1beta) and reactive oxygen species (ros) induced by lipopolysaccharide (lps) treatment in rat primary microglia in a dose-dependent manner. 2010-08-20 2023-08-12 rat
Birgit Kraus, Horst Wolff, Erich F Elstner, Jörg Heilman. Hyperforin is a modulator of inducible nitric oxide synthase and phagocytosis in microglia and macrophages. Naunyn-Schmiedeberg's archives of pharmacology. vol 381. issue 6. 2010-08-16. PMID:20369228. upon activation, microglia, the immunocompetent cells in the brain, get highly phagocytic and release pro-inflammatory mediators like nitric oxide (no). 2010-08-16 2023-08-12 mouse
Yan-Qiu Cui, Li-Juan Zhang, Ting Zhang, Ding-Zhen Luo, Yan-Jun Jia, Zi-Xuan Guo, Quan-Bin Zhang, Xuan Wang, Xiao-Min Wan. Inhibitory effect of fucoidan on nitric oxide production in lipopolysaccharide-activated primary microglia. Clinical and experimental pharmacology & physiology. vol 37. issue 4. 2010-08-06. PMID:19843098. inhibitory effect of fucoidan on nitric oxide production in lipopolysaccharide-activated primary microglia. 2010-08-06 2023-08-12 Not clear
Chung-Kwe Wang, Lih-Geeng Chen, Chi-Luan Wen, Wen-Chi Hou, Ling-Fang Hung, Shish-Jung Yen, Yi-Jyun Shen, Shyr-Yi Lin, Yu-Chih Lian. Neuroprotective activity of Vitis thunbergii var. taiwaniana extracts in vitro and in vivo. Journal of medicinal food. vol 13. issue 1. 2010-08-05. PMID:20136452. in this study, we found that the branch and leaf ethanol extracts of vtt significantly inhibited the inducible nitric oxide (no) synthase protein expression and no production in bv2 microglia. 2010-08-05 2023-08-12 Not clear
Jaegyu Hwang, Heehong Hwang, Ho-Won Lee, Kyoungho Su. Microglia signaling as a target of donepezil. Neuropharmacology. vol 58. issue 7. 2010-07-19. PMID:20153342. our conclusion is based on the measurement of nitric oxide and proinflammatory mediators using purified microglia cultures and microglia cell lines: donepezil attenuated microglial production of nitric oxide and tumor necrosis factor (tnf)-alpha, and suppressed the gene expression of inducible nitric oxide synthase, interleukin-1 beta, and tnf-alpha. 2010-07-19 2023-08-12 Not clear