All Relations between microglial cell and nitrogen monoxide

Publication Sentence Publish Date Extraction Date Species
Dae Young Jung, Heasuk Lee, Kyoungho Su. Pro-apoptotic activity of N-myc in activation-induced cell death of microglia. Journal of neurochemistry. vol 94. issue 1. 2005-08-08. PMID:15953367. tetracycline-based conditional expression of n-myc sensitized microglia to nitric oxide (no)-induced apoptosis. 2005-08-08 2023-08-12 Not clear
Bianca Marchetti, Pier Andrea Serra, Cataldo Tirolo, Francesca L'episcopo, Salvo Caniglia, Florinda Gennuso, Nuccio Testa, Egidio Miele, Speranza Desole, Nicholas Barden, Maria Concetta Moral. Glucocorticoid receptor-nitric oxide crosstalk and vulnerability to experimental parkinsonism: pivotal role for glia-neuron interactions. Brain research. Brain research reviews. vol 48. issue 2. 2005-07-15. PMID:15850669. the expression of inducible nitric oxide synthase (inos) in astrocytes and microglia and the production of large amounts of nitric oxide (no) are thought to contribute to dopaminergic neuron demise. 2005-07-15 2023-08-12 mouse
Rosario Luna-Medina, Marta Cortes-Canteli, Mercedes Alonso, Angel Santos, Ana Martínez, Ana Perez-Castill. Regulation of inflammatory response in neural cells in vitro by thiadiazolidinones derivatives through peroxisome proliferator-activated receptor gamma activation. The Journal of biological chemistry. vol 280. issue 22. 2005-07-12. PMID:15817469. in addition, thiadiazolidinones inhibited tumor necrosis factor-alpha and nitric oxide production and, concomitantly, protected cortical neurons from cell death induced by the cell-free supernatant from activated microglia. 2005-07-12 2023-08-12 Not clear
Rodrigo Herrera-Molina, Rommy von Bernhard. Transforming growth factor-beta 1 produced by hippocampal cells modulates microglial reactivity in culture. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837578. activated microglia produce superoxide anion (o2-) and nitric oxide (no), both of which can be neurotoxic. 2005-07-12 2023-08-12 Not clear
Claire L Gibson, Teresa C Coughlan, Sean P Murph. Glial nitric oxide and ischemia. Glia. vol 50. issue 4. 2005-06-28. PMID:15846796. understanding how nitric oxide production from microglia and astrocytes contributes to ischemic pathology is important for the development and application of future therapeutics based on inhibiting or amplifying its production in the injured brain. 2005-06-28 2023-08-12 Not clear
Kee-Ching G Jeng, Rolis C W Hou, Jing-Cheng Wang, Ling-In Pin. Sesamin inhibits lipopolysaccharide-induced cytokine production by suppression of p38 mitogen-activated protein kinase and nuclear factor-kappaB. Immunology letters. vol 97. issue 1. 2005-06-21. PMID:15626481. we showed that sesamin and sesamolin, major lignans of sesame oil, regulated lps-induced nitric oxide production in the murine microglia and bv-2 cell line. 2005-06-21 2023-08-12 mouse
Gabino Garrido, René Delgado, Yeny Lemus, Janet Rodríguez, Dagmar García, Alberto J Núñez-Sellé. Protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production on macrophages and microglia by a standard aqueous extract of Mangifera indica L. (VIMANG). Role of mangiferin isolated from the extract. Pharmacological research. vol 50. issue 2. 2005-06-20. PMID:15177305. protection against septic shock and suppression of tumor necrosis factor alpha and nitric oxide production on macrophages and microglia by a standard aqueous extract of mangifera indica l. (vimang). 2005-06-20 2023-08-12 mouse
S Thameem Dheen, Yan Jun, Zhou Yan, Samuel S W Tay, Eng Ang Lin. Retinoic acid inhibits expression of TNF-alpha and iNOS in activated rat microglia. Glia. vol 50. issue 1. 2005-06-16. PMID:15602748. the release of proinflammatory mediators such as tumor necrosis factor-alpha (tnf-alpha) and nitric oxide by microglia has been implicated in neurotoxicity in chronic neurodegenerative diseases such as alzheimer's disease. 2005-06-16 2023-08-12 rat
Michael L Selle. Simvastatin prevents 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine-induced striatal dopamine depletion and protein tyrosine nitration in mice. Brain research. vol 1037. issue 1-2. 2005-06-16. PMID:15777746. simvastatin inhibited the production of tumor necrosis factor (tnf)-alpha, nitric oxide, and superoxide in cultured rat microglia stimulated by lipopolysaccharide. 2005-06-16 2023-08-12 mouse
Nikolay M Filipov, Richard F Seegal, David A Lawrenc. Manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa B-dependent mechanism. Toxicological sciences : an official journal of the Society of Toxicology. vol 84. issue 1. 2005-06-08. PMID:15601679. manganese potentiates in vitro production of proinflammatory cytokines and nitric oxide by microglia through a nuclear factor kappa b-dependent mechanism. 2005-06-08 2023-08-12 Not clear
Paul D Storer, Jihong Xu, Janet Chavis, Paul D Dre. Peroxisome proliferator-activated receptor-gamma agonists inhibit the activation of microglia and astrocytes: implications for multiple sclerosis. Journal of neuroimmunology. vol 161. issue 1-2. 2005-05-27. PMID:15748950. the results show that tzds and 15d-pgj(2) are effective in inhibiting production of nitric oxide, the pro-inflammatory cytokines tnf-alpha, il-1beta, and il-6, and the chemokine mcp-1 from microglia and astrocytes. 2005-05-27 2023-08-12 mouse
Xijin Wang, Shengdi Chen, Guozhao Ma, Min Ye, Guoqiang L. Genistein protects dopaminergic neurons by inhibiting microglial activation. Neuroreport. vol 16. issue 3. 2005-05-16. PMID:15706233. genistein also inhibited lipopolysaccharide-induced microglia activation and production of tumor necrosis factor-alpha, nitric oxide and superoxide in mesencephalic neuron-glia cultures and microglia-enriched cultures. 2005-05-16 2023-08-12 rat
Thierry Muller, Luc Grandbarbe, Eleonora Morga, Paul Heuschling, Bang Lu. Tocopherol long chain fatty alcohols decrease the production of TNF-alpha and NO radicals by activated microglial cells. Bioorganic & medicinal chemistry letters. vol 14. issue 24. 2005-04-20. PMID:15546721. specifically, the 2-(12-hydroxy-dodecyl)-2,5,7,8-tetramethyl-chroman-6-ol, the tfa bearing 12 carbon atoms on the side chain (n=12), shows the most potent inhibition of secretion on nitric oxide (no) and tumour necrosis factor-alpha (tnf-alpha) by lipopolysaccharide (lps)-activated microglia. 2005-04-20 2023-08-12 Not clear
Masahiro Banno, Tetsuya Mizuno, Hideki Kato, Guiqin Zhang, Jun Kawanokuchi, Jinyan Wang, Reiko Kuno, Shijie Jin, Hideyuki Takeuchi, Akio Suzumur. The radical scavenger edaravone prevents oxidative neurotoxicity induced by peroxynitrite and activated microglia. Neuropharmacology. vol 48. issue 2. 2005-04-13. PMID:15695167. we examined the effect of edaravone on the production of nitric oxide (no), reactive oxygen species (ros) and proinflammatory cytokines by activated microglia, and we also examined its neuroprotective role in cortical neuronal cultures oxidatively stressed by the peroxynitrite donor n-morpholinosydnonimine (sin-1) or activated microglia. 2005-04-13 2023-08-12 Not clear
Kazuya Takahashi, Christian D P Rochford, Harald Neuman. Clearance of apoptotic neurons without inflammation by microglial triggering receptor expressed on myeloid cells-2. The Journal of experimental medicine. vol 201. issue 4. 2005-04-11. PMID:15728241. knockdown of trem2 in microglia inhibited phagocytosis of apoptotic neurons and increased gene transcription of tumor necrosis factor alpha and nitric oxide synthase-2, whereas overexpression of trem2 increased phagocytosis and decreased microglial proinflammatory responses. 2005-04-11 2023-08-12 Not clear
Kohichi Kawahara, Masataka Mori, Hitoshi Nakayam. [NO-induced apoptosis and ER stress in microglia]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 124. issue 6. 2005-04-05. PMID:15572844. nitric oxide (no) produced by activated microglia is an important contributor to neuronal damage. 2005-04-05 2023-08-12 mouse
M Li, K Pisalyaput, M Galvan, A J Tenne. Macrophage colony stimulatory factor and interferon-gamma trigger distinct mechanisms for augmentation of beta-amyloid-induced microglia-mediated neurotoxicity. Journal of neurochemistry. vol 91. issue 3. 2005-03-24. PMID:15485493. in contrast, no induction of nitric oxide production was detected for microglia treated with mcsf/fa beta. 2005-03-24 2023-08-12 Not clear
Sandra Ebert, Joachim Gerber, Steffi Bader, Frank Mühlhauser, Katrin Brechtel, Timothy J Mitchell, Roland Na. Dose-dependent activation of microglial cells by Toll-like receptor agonists alone and in combination. Journal of neuroimmunology. vol 159. issue 1-2. 2005-03-18. PMID:15652406. upon stimulation with agonists of tlr2, tlr4, and tlr9, nitric oxide (no) and tumor necrosis factor-alpha (tnf-alpha) were released by primary mouse microglial cell cultures. 2005-03-18 2023-08-12 mouse
George Hsiao, Tsorng H Fong, Nien H Tzu, Kuan H Lin, Duen S Chou, Joen R She. A potent antioxidant, lycopene, affords neuroprotection against microglia activation and focal cerebral ischemia in rats. In vivo (Athens, Greece). vol 18. issue 3. 2005-03-07. PMID:15341191. we investigated the effects of a potent antioxidant, lycopene, on the free radical-scavenging activity as evaluated by the dpph test and lipid peroxidation in rat brain homogenates as well as nitric oxide (no) formation in cultured microglia stimulated by lipopolysaccharide. 2005-03-07 2023-08-12 rat
Gilad Twig, Solomon A Graf, Mark A Messerli, Peter J S Smith, Seung H Yoo, Orian S Shiriha. Synergistic amplification of beta-amyloid- and interferon-gamma-induced microglial neurotoxic response by the senile plaque component chromogranin A. American journal of physiology. Cell physiology. vol 288. issue 1. 2005-03-07. PMID:15342341. microglia induce neurodegeneration primarily by secreting nitric oxide (no), tumor necrosis factor-alpha (tnfalpha), and hydrogen peroxide. 2005-03-07 2023-08-12 rat