| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Shalini Elangovan, R M Damian Holsinge. Cyclical amyloid beta-astrocyte activity induces oxidative stress in Alzheimer's disease. Biochimie. vol 171-172. 2020-12-14. PMID:32061803. |
glial cell involvement in alzheimer's disease (ad) is multi-faceted. |
2020-12-14 |
2023-08-13 |
Not clear |
| Rea Pihlaja, Merja Haaparanta-Solin, Juha O Rinn. The Anti-Inflammatory Effects of Lipoxygenase and Cyclo-Oxygenase Inhibitors in Inflammation-Induced Human Fetal Glia Cells and the Aβ Degradation Capacity of Human Fetal Astrocytes in an Frontiers in neuroscience. vol 11. 2020-10-01. PMID:28611577. |
the anti-inflammatory effects of lipoxygenase and cyclo-oxygenase inhibitors in inflammation-induced human fetal glia cells and the aβ degradation capacity of human fetal astrocytes in an chronic inflammation is a common phenomenon present in the background of multiple neurodegenerative diseases, including alzheimer's disease (ad). |
2020-10-01 |
2023-08-13 |
human |
| Yoo Sung Kim, Hae Myeong Jung, Bo-Eun Yoo. Exploring glia to better understand Alzheimer's disease. Animal cells and systems. vol 22. issue 4. 2020-10-01. PMID:30460100. |
exploring glia to better understand alzheimer's disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Beatriz G Pérez-Nievas, Alberto Serrano-Poz. Editorial: The Role of Glia in Alzheimer's Disease. Frontiers in neurology. vol 9. 2020-10-01. PMID:30692961. |
editorial: the role of glia in alzheimer's disease. |
2020-10-01 |
2023-08-13 |
Not clear |
| Maria Anele Romeo, Alberto Faggioni, Mara Ciron. Could autophagy dysregulation link neurotropic viruses to Alzheimer's disease? Neural regeneration research. vol 14. issue 9. 2020-10-01. PMID:31089040. |
moreover, herpesvirus infection of central nervous system cells such as glia and microglia can increase the production of oxidant species through the alteration of mitochondrial dynamics and promote inflammation, another hallmark of alzheimer's disease. |
2020-10-01 |
2023-08-13 |
human |
| Suvi Pöyhönen, Safak Er, Andrii Domanskyi, Mikko Airavaar. Effects of Neurotrophic Factors in Glial Cells in the Central Nervous System: Expression and Properties in Neurodegeneration and Injury. Frontiers in physiology. vol 10. 2020-10-01. PMID:31105589. |
an increasing amount of evidence points to the critical importance of glia in mediating neurodegeneration in alzheimer's and parkinson's diseases (ad, pd), and in ischemic stroke, where microglia are involved in initial tissue clearance, and astrocytes in the subsequent formation of a glial scar. |
2020-10-01 |
2023-08-13 |
Not clear |
| Maria Rosanna Bronzuoli, Roberta Facchinetti, Marta Valenza, Tommaso Cassano, Luca Steardo, Caterina Scuder. Astrocyte Function Is Affected by Aging and Not Alzheimer's Disease: A Preliminary Investigation in Hippocampi of 3xTg-AD Mice. Frontiers in pharmacology. vol 10. 2020-10-01. PMID:31244658. |
old age is a risk factor for alzheimer's disease (ad), which is characterized by hippocampal impairment together with substantial changes in glial cell functions. |
2020-10-01 |
2023-08-13 |
mouse |
| Pieter Vancamp, Lucile Butruille, Barbara A Demeneix, Sylvie Remau. Thyroid Hormone and Neural Stem Cells: Repair Potential Following Brain and Spinal Cord Injury. Frontiers in neuroscience. vol 14. 2020-10-01. PMID:32982671. |
here, we discuss whether th could have beneficial actions in various pathological contexts too, by evaluating recent data obtained in mammalian models of multiple sclerosis (ms; loss of oligodendroglial cells), alzheimer's disease (loss of neuronal cells), stroke and spinal cord injury (neuroglial cell loss). |
2020-10-01 |
2023-08-13 |
Not clear |
| Heejung Chun, Ian Marriott, C Justin Lee, Hansang Ch. Elucidating the Interactive Roles of Glia in Alzheimer's Disease Using Established and Newly Developed Experimental Models. Frontiers in neurology. vol 9. 2020-09-30. PMID:30319529. |
elucidating the interactive roles of glia in alzheimer's disease using established and newly developed experimental models. |
2020-09-30 |
2023-08-13 |
Not clear |
| Carolina Osorio, Tulasi Kanukuntla, Eddie Diaz, Nyla Jafri, Michael Cummings, Adonis Sfer. The Post-amyloid Era in Alzheimer's Disease: Trust Your Gut Feeling. Frontiers in aging neuroscience. vol 11. 2020-09-30. PMID:31297054. |
microbiota-induced senescence is a gradually emerging concept promoted by the discovery of pathogens and their products in alzheimer's disease brains associated with senescent neurons, glia, and endothelial cells. |
2020-09-30 |
2023-08-13 |
Not clear |
| Tuane Bazanella Sampaio, Anne Suely Savall, Maria Eduarda Ziani Gutierrez, Simone Pinto. Neurotrophic factors in Alzheimer's and Parkinson's diseases: implications for pathogenesis and therapy. Neural regeneration research. vol 12. issue 4. 2020-09-29. PMID:28553325. |
based on recent reports, this review discusses the main findings related to the neurotrophic factor support - mainly brain-derived neurotrophic factor and glial cell line-derived neurotrophic factor - in the survival, proliferation and maturation of affected neurons in alzheimer's disease and parkinson's disease as well as their putative application as new therapeutic approach for these diseases management. |
2020-09-29 |
2023-08-13 |
Not clear |
| Ramasamy Thangavel, Duraisamy Kempuraj, Smita Zaheer, Sudhanshu Raikwar, Mohammad E Ahmed, Govindhasamy Pushpavathi Selvakumar, Shankar S Iyer, Asgar Zahee. Glia Maturation Factor and Mitochondrial Uncoupling Proteins 2 and 4 Expression in the Temporal Cortex of Alzheimer's Disease Brain. Frontiers in aging neuroscience. vol 9. 2020-09-29. PMID:28572767. |
glia maturation factor and mitochondrial uncoupling proteins 2 and 4 expression in the temporal cortex of alzheimer's disease brain. |
2020-09-29 |
2023-08-13 |
Not clear |
| Swathi Beladakere Ramaswamy, Sachin M Bhagavan, Harleen Kaur, Gema E Giler, Duraisamy Kempuraj, Ramasamy Thangavel, Mohammad Ejaz Ahmed, Govindhasamy Pushpavathi Selvakumar, Sudhanshu P Raikwar, Smita Zaheer, Shankar S Iyer, Raghav Govindarajan, Asgar Zahee. Glia Maturation Factor in the Pathogenesis of Alzheimer's disease. Open access journal of neurology & neurosurgery. vol 12. issue 3. 2020-09-28. PMID:32775957. |
glia maturation factor in the pathogenesis of alzheimer's disease. |
2020-09-28 |
2023-08-13 |
Not clear |
| Jean-Christophe Delpech, Shawn Herron, Mina B Botros, Tsuneya Ikez. Neuroimmune Crosstalk through Extracellular Vesicles in Health and Disease. Trends in neurosciences. vol 42. issue 5. 2020-09-15. PMID:30926143. |
this review aims to organize recent research highlighting the role of evs in health and neurodegenerative disorders, with a specific focus on neuroimmune interactions between neurons and glia in alzheimer's disease. |
2020-09-15 |
2023-08-13 |
Not clear |
| Arsalan Hashemiaghdam, Magdalena Mrocze. Microglia heterogeneity and neurodegeneration: The emerging paradigm of the role of immunity in Alzheimer's disease. Journal of neuroimmunology. vol 341. 2020-09-03. PMID:32045774. |
recent studies, exposing transcriptomic clusters of disease-related cells and analyzing sequenced rna from sorted myeloid cells, seem to confirm the hypothesis of the central role of glia in the pathogenesis of alzheimer's disease. |
2020-09-03 |
2023-08-13 |
human |
| Yingyue Zhou, Wilbur M Song, Prabhakar S Andhey, Amanda Swain, Tyler Levy, Kelly R Miller, Pietro L Poliani, Manuela Cominelli, Shikha Grover, Susan Gilfillan, Marina Cella, Tyler K Ulland, Konstantin Zaitsev, Akinori Miyashita, Takeshi Ikeuchi, Makoto Sainouchi, Akiyoshi Kakita, David A Bennett, Julie A Schneider, Michael R Nichols, Sean A Beausoleil, Jason D Ulrich, David M Holtzman, Maxim N Artyomov, Marco Colonn. Human and mouse single-nucleus transcriptomics reveal TREM2-dependent and TREM2-independent cellular responses in Alzheimer's disease. Nature medicine. vol 26. issue 1. 2020-04-13. PMID:31932797. |
glia have been implicated in alzheimer's disease (ad) pathogenesis. |
2020-04-13 |
2023-08-13 |
mouse |
| Elodie Martin, Majid Amar, Carine Dalle, Ihsen Youssef, Céline Boucher, Caroline Le Duigou, Matthias Brückner, Annick Prigent, Véronique Sazdovitch, Annett Halle, Jean M Kanellopoulos, Bertrand Fontaine, Benoît Delatour, Cécile Delarass. New role of P2X7 receptor in an Alzheimer's disease mouse model. Molecular psychiatry. vol 24. issue 1. 2020-01-06. PMID:29934546. |
extracellular aggregates of amyloid β (aβ) peptides, which are characteristic of alzheimer's disease (ad), act as an essential trigger for glial cell activation and the release of atp, leading to the stimulation of purinergic receptors, especially the p2x7 receptor (p2x7r). |
2020-01-06 |
2023-08-13 |
mouse |
| Kelly L. Jordan-Sciutto, Kathleen Morgan, Robert Bowse. Increased Cyclin G1 Immunoreactivity During Alzheimer's Disease. Journal of Alzheimer's disease : JAD. vol 1. issue 6. 2019-11-20. PMID:12214116. |
numerous proteins are alternatively expressed in neurons and glia during alzheimer's disease (ad) and may contribute to the regulation of neuronal cell death or function in regenerative responses to neuronal injury. |
2019-11-20 |
2023-08-12 |
human |
| G Bartzoki. Inter-Species Glia Differences: Implications for Successful Translation of Transgenic Rodent Alzheimer's Disease Model Treatment Using Bexarotene. The journal of prevention of Alzheimer's disease. vol 1. issue 1. 2019-11-20. PMID:29261220. |
inter-species glia differences: implications for successful translation of transgenic rodent alzheimer's disease model treatment using bexarotene. |
2019-11-20 |
2023-08-13 |
mouse |
| Jaymie R Voorhees, Matthew T Remy, Coral J Cintrón-Pérez, Eli El Rassi, Michael Z Khan, Laura M Dutca, Terry C Yin, Latisha N McDaniel, Noelle S Williams, Daniel J Brat, Andrew A Piepe. (-)-P7C3-S243 Protects a Rat Model of Alzheimer's Disease From Neuropsychiatric Deficits and Neurodegeneration Without Altering Amyloid Deposition or Reactive Glia. Biological psychiatry. vol 84. issue 7. 2019-10-18. PMID:29246437. |
(-)-p7c3-s243 protects a rat model of alzheimer's disease from neuropsychiatric deficits and neurodegeneration without altering amyloid deposition or reactive glia. |
2019-10-18 |
2023-08-13 |
rat |