| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaoyan Zheng, Wenjia Lin, Yimin Jiang, Kejia Lu, Wenjing Wei, Qingwei Huo, Shaoyang Cui, Xifei Yang, Min Li, Nenggui Xu, Chunzhi Tang, Ju-Xian Son. Electroacupuncture ameliorates beta-amyloid pathology and cognitive impairment in Alzheimer disease via a novel mechanism involving activation of TFEB (transcription factor EB). Autophagy. vol 17. issue 11. 2021-12-11. PMID:33622188. |
tnea reduced app (amyloid beta (a4) precursor protein), c-terminal fragments (ctfs) of app and aβ load, and inhibited glial cell activation in the prefrontal cortex and hippocampus of 5xfad. |
2021-12-11 |
2023-08-13 |
human |
| Célia Lentini, Marie d'Orange, Nicolás Marichal, Marie-Madeleine Trottmann, Rory Vignoles, Louis Foucault, Charlotte Verrier, Céline Massera, Olivier Raineteau, Karl-Klaus Conzelmann, Sylvie Rival-Gervier, Antoine Depaulis, Benedikt Berninger, Christophe Heinric. Reprogramming reactive glia into interneurons reduces chronic seizure activity in a mouse model of mesial temporal lobe epilepsy. Cell stem cell. vol 28. issue 12. 2021-12-06. PMID:34592167. |
using a mtle mouse model, we show that retrovirus-driven expression of ascl1 and dlx2 in reactive hippocampal glia in situ, or in cortical astroglia grafted in the epileptic hippocampus, causes efficient reprogramming into ins exhibiting hallmarks of interneurons. |
2021-12-06 |
2023-08-13 |
mouse |
| Murat Sırrı Akosman, Ruhi Türkmen, Hasan Hüseyin Demire. Investigation of the protective effect of resveratrol in an MK-801-induced mouse model of schizophrenia. Environmental science and pollution research international. vol 28. issue 46. 2021-12-02. PMID:34322799. |
according to the results obtained, this study showed for the first time that resveratrol prevented glial cell infiltration induced in the brain by mk-801 and shrinkage of nerve cell nuclei in the hippocampus and corpus callosum. |
2021-12-02 |
2023-08-13 |
mouse |
| Alish B Palmos, Rodrigo R R Duarte, Demelza M Smeeth, Erin C Hedges, Douglas F Nixon, Sandrine Thuret, Timothy R Powel. Lithium treatment and human hippocampal neurogenesis. Translational psychiatry. vol 11. issue 1. 2021-11-17. PMID:34718328. |
we observed that high-dose lithium treatment in human hippocampal progenitors increased the generation of neuroblasts (p ≤ 0.01), neurons (p ≤ 0.01), and glia (p ≤ 0.001), alongside the expression of genes, which regulate the volume of the molecular layer of the dentate gyrus. |
2021-11-17 |
2023-08-13 |
human |
| Elodie M Richard, Somayeh Bakhtiari, Ashley P L Marsh, Rauan Kaiyrzhanov, Matias Wagner, Sheetal Shetty, Alex Pagnozzi, Sandra M Nordlie, Brandon S Guida, Patricia Cornejo, Helen Magee, James Liu, Bethany Y Norton, Richard I Webster, Lisa Worgan, Hakon Hakonarson, Jiankang Li, Yiran Guo, Mahim Jain, Alyssa Blesson, Lance H Rodan, Mary-Alice Abbott, Anne Comi, Julie S Cohen, Bader Alhaddad, Thomas Meitinger, Dominic Lenz, Andreas Ziegler, Urania Kotzaeridou, Theresa Brunet, Anna Chassevent, Constance Smith-Hicks, Joseph Ekstein, Tzvi Weiden, Andreas Hahn, Nazira Zharkinbekova, Peter Turnpenny, Arianna Tucci, Melissa Yelton, Rita Horvath, Serdal Gungor, Semra Hiz, Yavuz Oktay, Hanns Lochmuller, Marcella Zollino, Manuela Morleo, Giuseppe Marangi, Vincenzo Nigro, Annalaura Torella, Michele Pinelli, Simona Amenta, Ralf A Husain, Benita Grossmann, Marion Rapp, Claudia Steen, Iris Marquardt, Mona Grimmel, Ute Grasshoff, G Christoph Korenke, Marta Owczarek-Lipska, John Neidhardt, Francesca Clementina Radio, Cecilia Mancini, Dianela Judith Claps Sepulveda, Kirsty McWalter, Amber Begtrup, Amy Crunk, Maria J Guillen Sacoto, Richard Person, Rhonda E Schnur, Maria Margherita Mancardi, Florian Kreuder, Pasquale Striano, Federico Zara, Wendy K Chung, Warren A Marks, Clare L van Eyk, Dani L Webber, Mark A Corbett, Kelly Harper, Jesia G Berry, Alastair H MacLennan, Jozef Gecz, Marco Tartaglia, Vincenzo Salpietro, John Christodoulou, Jan Kaslin, Sergio Padilla-Lopez, Kaya Bilguvar, Alexander Munchau, Zubair M Ahmed, Robert B Hufnagel, Michael C Fahey, Reza Maroofian, Henry Houlden, Heinrich Sticht, Shrikant M Mane, Aboulfazl Rad, Barbara Vona, Sheng Chih Jin, Tobias B Haack, Christine Makowski, Yoel Hirsch, Saima Riazuddin, Michael C Krue. Bi-allelic variants in SPATA5L1 lead to intellectual disability, spastic-dystonic cerebral palsy, epilepsy, and hearing loss. American journal of human genetics. vol 108. issue 10. 2021-11-15. PMID:34626583. |
immunofluorescent imaging in rat hippocampal neurons revealed localization of spata5l1 in neuronal and glial cell nuclei and more prominent expression in neurons. |
2021-11-15 |
2023-08-13 |
human |
| Ryota Araki, Hayato Tachioka, Ayami Kita, Hironori Fujiwara, Kazufumi Toume, Kinzo Matsumoto, Takeshi Yab. Kihito prevents corticosterone-induced brain dysfunctions in mice. Journal of traditional and complementary medicine. vol 11. issue 6. 2021-11-13. PMID:34765515. |
hippocampal cell survival, the number of hippocampal new-born immature neurons, hippocampal and accumbal dendritic spine density and mrna levels for neurotrophic factors such as glial cell line-derived neurotrophic factor (gdnf) were decreased in cort-treated mice without kit treatment. |
2021-11-13 |
2023-08-13 |
mouse |
| Elise C Cope, Anna D Zych, Nicole J Katchur, Renée C Waters, Blake J Laham, Emma J Diethorn, Christin Y Park, William R Meara, Elizabeth Goul. Atypical perineuronal nets in the CA2 region interfere with social memory in a mouse model of social dysfunction. Molecular psychiatry. 2021-11-09. PMID:34183768. |
we sought to identify potential mechanisms of social memory dysfunction in the hippocampus by investigating features of neurons, glia, and the extracellular matrix (ecm) of btbr mice, an inbred mouse strain with deficient social memory. |
2021-11-09 |
2023-08-13 |
mouse |
| Allison M Bond, Guo-Li Ming, Hongjun Son. Ontogeny of adult neural stem cells in the mammalian brain. Current topics in developmental biology. vol 142. 2021-11-05. PMID:33706926. |
neural stem cells (nscs) persist into adulthood in the subgranular zone (sgz) of the dentate gyrus in the hippocampus and in the ventricular-subventricular zone (v-svz) of the lateral ventricles, where they generate new neurons and glia cells that contribute to neural plasticity. |
2021-11-05 |
2023-08-13 |
Not clear |
| Luke Parkitny, Mirjana Maletic-Savati. Glial PAMPering and DAMPening of Adult Hippocampal Neurogenesis. Brain sciences. vol 11. issue 10. 2021-10-26. PMID:34679362. |
the hippocampal neurogenic niche hosts neural progenitors, glia, and vasculature, which all respond to intrinsic and environmental cues, helping determine their current state and ultimate fate. |
2021-10-26 |
2023-08-13 |
Not clear |
| Nathan A DeCarolis, Phillip D Rivera, Francisca Ahn, Wellington Z Amaral, Junie A LeBlanc, Shveta Malhotra, Hung-Ying Shih, David Petrik, Neal Melvin, Benjamin P C Chen, Amelia J Eisc. Life sciences in space research. vol 2. 2021-10-21. PMID:25170435. |
given that neurogenesis in the hippocampus has been linked to learning and memory, we investigated the response and recovery of neurogenesis and neural stem cells in the adult mouse hippocampal dentate gyrus after hze particle exposure using two nestin transgenic reporter mouse lines to label and track radial glia stem cells (nestin-gfp and nestin-creer |
2021-10-21 |
2023-08-13 |
mouse |
| Xiao Zhang, Yao Liu, Xiaoqi Hong, Xia Li, Charles K Meshul, Cynthia Moore, Yabing Yang, Yanfei Han, Wei-Guang Li, Xin Qi, Huifang Lou, Shumin Duan, Tian-Le Xu, Xiaoping Ton. NG2 glia-derived GABA release tunes inhibitory synapses and contributes to stress-induced anxiety. Nature communications. vol 12. issue 1. 2021-10-21. PMID:34593806. |
here, we report that ng2 glia form synaptic complexes with hippocampal interneurons and that selective photostimulation of ng2 glia (expressing channelrhodopsin-2) functionally drives gaba release and enhances inhibitory synaptic transmission onto proximal interneurons in a microcircuit. |
2021-10-21 |
2023-08-13 |
Not clear |
| Lushuang Xie, Yi Liu, Ning Zhang, Chenyu Li, Aaron F Sandhu, George Williams, Yan Shen, Hongying Li, Qiaofeng Wu, Shuguang Y. Electroacupuncture Improves M2 Microglia Polarization and Glia Anti-inflammation of Hippocampus in Alzheimer's Disease. Frontiers in neuroscience. vol 15. 2021-10-15. PMID:34646113. |
electroacupuncture improves m2 microglia polarization and glia anti-inflammation of hippocampus in alzheimer's disease. |
2021-10-15 |
2023-08-13 |
Not clear |
| Ying-Shao Lin, Ching-Kuan Liu, Hsiang-Chun Lee, Mei-Chuan Chou, Liang-Yin Ke, Chu-Huang Chen, Shiou-Lan Che. Electronegative very-low-density lipoprotein induces brain inflammation and cognitive dysfunction in mice. Scientific reports. vol 11. issue 1. 2021-10-14. PMID:33727609. |
however, in mice injected with metvldl, plasma and brain tnf-α and aβ-42 levels and glial cell activation in the mpfc and whole hippocampus were higher than those in control mice. |
2021-10-14 |
2023-08-13 |
mouse |
| Orly Lazarov, Richard D Minshall, Marcelo G Bonin. Harnessing neurogenesis in the adult brain-A role in type 2 diabetes mellitus and Alzheimer's disease. International review of neurobiology. vol 155. 2021-10-11. PMID:32854856. |
hippocampal neurogenesis is the generation of new neurons and glia in the adult brain throughout life. |
2021-10-11 |
2023-08-13 |
mouse |
| William Stevenson, Yoshiki Hase, Elle Wilson, Annabel Hollins, Mai Hase, Abdel Ennaceur, Lucy Craggs, Masafumi Ihara, Karen Horsburgh, Raj N Kalari. Long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment. Brain research bulletin. vol 163. 2021-09-29. PMID:32707262. |
long-term effects of experimental carotid stenosis on hippocampal infarct pathology, neurons and glia and amelioration by environmental enrichment. |
2021-09-29 |
2023-08-13 |
mouse |
| Ye Wang, Amy K Y Fu, Nancy Y I. IL-33/ST2 Signaling Regulates Synaptic Plasticity and Homeostasis in the Adult Hippocampal Circuitry. DNA and cell biology. vol 40. issue 9. 2021-09-23. PMID:34297618. |
emerging evidence suggests that the crosstalk between neurons and glia in the adult hippocampus is region specific and that the mechanisms controlling this process are critically dependent on secreted factors. |
2021-09-23 |
2023-08-13 |
Not clear |
| Jiafeng Zhou, Gaoao Liu, Xiaoling Zhang, Chao Wu, Mengjie Ma, Jiarui Wu, Lin Hou, Bin Yin, Boqin Qiang, Pengcheng Shu, Xiaozhong Pen. Comparison of the Spatiotemporal Expression Patterns of Three Cre Lines, Emx1IRES-Cre, D6-Cre and hGFAP-Cre, Commonly Used in Neocortical Development Research. Cerebral cortex (New York, N.Y. : 1991). 2021-09-22. PMID:34550336. |
meanwhile, we used the three cre lines to mediate dicer knockout and observed inconsistent phenotypes, including discrepancies in radial glial cell number, survival and neurogenesis in the neocortex and hippocampus. |
2021-09-22 |
2023-08-13 |
mouse |
| Priscilla Bluemel, Jonathan Wickel, Benedikt Grünewald, Mihai Ceanga, Silke Keiner, Otto W Witte, Christoph Redecker, Christian Geis, Albrecht Kunz. Sepsis promotes gliogenesis and depletes the pool of radial glia like stem cells in the hippocampus. Experimental neurology. vol 338. 2021-09-17. PMID:33387461. |
sepsis promotes gliogenesis and depletes the pool of radial glia like stem cells in the hippocampus. |
2021-09-17 |
2023-08-13 |
Not clear |
| Alireza Torfeh, Zohreh Abdolmaleki, Sepideh Nazarian, Seyed Hamed Shirazi Beheshtih. Modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. Anatomical record (Hoboken, N.J. : 2007). vol 304. issue 9. 2021-09-03. PMID:33345406. |
modafinil-coated nanoparticle increases expressions of brain-derived neurotrophic factor, glial cell line-derived neurotrophic factor and neuronal nuclear protein, and protects against middle cerebral artery occlusion-induced neuron apoptosis in the rat hippocampus. |
2021-09-03 |
2023-08-13 |
human |
| Marie-Claire Ung, Lillian Garrett, Claudia Dalke, Valentin Leitner, Daniel Dragosa, Daniela Hladik, Frauke Neff, Florian Wagner, Horst Zitzelsberger, Gregor Miller, Martin Hrabĕ de Angelis, Ute Rößler, Daniela Vogt Weisenhorn, Wolfgang Wurst, Jochen Graw, Sabine M Hölte. Dose-dependent long-term effects of a single radiation event on behaviour and glial cells. International journal of radiation biology. vol 97. issue 2. 2021-08-27. PMID:33264576. |
therefore, we analysed the long-term effects of a single low-dose irradiation exposure at 10 weeks of age compared to medium and higher doses on locomotor, emotion-related and sensorimotor behaviour in mice as well as on hippocampal glial cell populations. |
2021-08-27 |
2023-08-13 |
mouse |