| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Bente Pakkenberg, Dorte Pelvig, Lisbeth Marner, Mads J Bundgaard, Hans Jørgen G Gundersen, Jens R Nyengaard, Lisbeth Regeu. Aging and the human neocortex. Experimental gerontology. vol 38. issue 1-2. 2003-05-12. PMID:12543266. |
the difference in total number of neurons was found to be less than 10% over the age range from 20 to 90 years, while the glial cell number in six elderly individuals, mean age 89.2 years, showed an average number of 36 billion glial cells, which was not statistically significantly different from the 39 billion glial cells in the neocortex of six young individuals with a mean age of 26.2 years. |
2003-05-12 |
2023-08-12 |
human |
| Thomas A Hasling, Marcin Gierdalski, Beata Jablonska, Sharon L Julian. A radialization factor in normal cortical plate restores disorganized radial glia and disrupted migration in a model of cortical dysplasia. The European journal of neuroscience. vol 17. issue 3. 2003-04-10. PMID:12581165. |
treatment of pregnant ferrets on embryonic day 24 (e24) with the antimitotic methylazoxy methanol (mam) leads to a specific constellation of effects in newborn kits, which include a very thin and poorly laminated neocortex, disruption of radial glial cell morphology with early differentiation into astrocytes, and abnormal positioning of cajal-retzius cells. |
2003-04-10 |
2023-08-12 |
Not clear |
| X S Wang, W Y Ong, J R Conno. A light and electron microscopic study of the iron transporter protein DMT-1 in the monkey cerebral neocortex and hippocampus. Journal of neurocytology. vol 30. issue 4. 2002-05-23. PMID:11875282. |
light to moderate dmt-1 staining was observed in glial cell bodies in the neocortex, the subcortical white matter, and the hippocampus. |
2002-05-23 |
2023-08-12 |
monkey |
| X S Wang, W Y Ong, J R Conno. A light and electron microscopic study of the iron transporter protein DMT-1 in the monkey cerebral neocortex and hippocampus. Journal of neurocytology. vol 30. issue 4. 2002-05-23. PMID:11875282. |
in the neocortex, the glial cell bodies displayed the morphological features of protoplasmic astrocytes. |
2002-05-23 |
2023-08-12 |
monkey |
| S V Westmoreland, X Alvarez, C deBakker, P Aye, M L Wilson, K C Williams, A A Lackne. Developmental expression patterns of CCR5 and CXCR4 in the rhesus macaque brain. Journal of neuroimmunology. vol 122. issue 1-2. 2002-02-21. PMID:11777554. |
ccr5 and cxcr4 were detected by immunohistochemistry and immunofluorescence within the cytoplasm of subpopulations of neurons in the neocortex, hippocampus, basal nuclei, thalamus, brain stem, and cerebellum and by flow cytometry on the surface of neurons and glia. |
2002-02-21 |
2023-08-12 |
monkey |
| H Wichterle, D H Turnbull, S Nery, G Fishell, A Alvarez-Buyll. In utero fate mapping reveals distinct migratory pathways and fates of neurons born in the mammalian basal forebrain. Development (Cambridge, England). vol 128. issue 19. 2001-12-04. PMID:11585802. |
recent studies suggest that neurons born in the developing basal forebrain migrate long distances perpendicularly to radial glia and that many of these cells reach the developing neocortex. |
2001-12-04 |
2023-08-12 |
mouse |
| M Stoltenberg, J A Hogenhuis, J J Hauw, G Dansche. Autometallographic tracing of bismuth in human brain autopsies. Journal of neuropathology and experimental neurology. vol 60. issue 7. 2001-07-19. PMID:11444799. |
histochemical analyses demonstrate that bismuth accumulated in neurons and glia cells in the brain regions examined (neocortex, cerebellum, thalamus, hippocampus). |
2001-07-19 |
2023-08-12 |
human |
| A C Puche, M T Shiple. Radial glia development in the mouse olfactory bulb. The Journal of comparative neurology. vol 434. issue 1. 2001-06-28. PMID:11329125. |
these results showed that olfactory bulb radial glia do not form straight parallel structures as do radial glia in the neocortex but rather have a convoluted trajectory from the ventricle to the bulb surface. |
2001-06-28 |
2023-08-12 |
mouse |
| S C Noctor, A C Flint, T A Weissman, R S Dammerman, A R Kriegstei. Neurons derived from radial glial cells establish radial units in neocortex. Nature. vol 409. issue 6821. 2001-03-08. PMID:11217860. |
the neocortex of the adult brain consists of neurons and glia that are generated by precursor cells of the embryonic ventricular zone. |
2001-03-08 |
2023-08-12 |
Not clear |
| S C Noctor, A C Flint, T A Weissman, R S Dammerman, A R Kriegstei. Neurons derived from radial glial cells establish radial units in neocortex. Nature. vol 409. issue 6821. 2001-03-08. PMID:11217860. |
our results support the concept that a lineage relationship between neurons and proliferative radial glia may underlie the radial organization of neocortex. |
2001-03-08 |
2023-08-12 |
Not clear |
| L Just, F Mörl, C Bärmann, C Olenik, D K Meye. Evidence for cell specific regulation by PACAP38 of the proenkephalin gene expression in neocortical cells. Glia. vol 30. issue 3. 2000-06-09. PMID:10756074. |
during the first postnatal week, glial cell production for the neocortex continues in the neocortical subventricular zone. |
2000-06-09 |
2023-08-12 |
Not clear |
| S W Levison, G M Young, J E Goldma. Cycling cells in the adult rat neocortex preferentially generate oligodendroglia. Journal of neuroscience research. vol 57. issue 4. 1999-09-09. PMID:10440893. |
to determine whether new glial cells in the adult cortex arise from resident progenitors and to determine the glial types to which these progenitors give rise to, cells in the perinatal subventricular zone (svz) were labeled with replication-deficient retroviral vectors, and clonal clusters of glia in the neocortex were examined from 1 week to 8 months of age. |
1999-09-09 |
2023-08-12 |
rat |
| S C Noctor, S L Palmer, T Hasling, S L Julian. Interference with the development of early generated neocortex results in disruption of radial glia and abnormal formation of neocortical layers. Cerebral cortex (New York, N.Y. : 1991). vol 9. issue 2. 1999-07-07. PMID:10220225. |
interference with the development of early generated neocortex results in disruption of radial glia and abnormal formation of neocortical layers. |
1999-07-07 |
2023-08-12 |
Not clear |
| J W Unge. Glial reaction in aging and Alzheimer's disease. Microscopy research and technique. vol 43. issue 1. 1999-06-04. PMID:9829455. |
in normal aging, no global glia proliferation is found morphologically, but reactive gliosis has been described in specific areas of the limbic system and neocortex that undergo selective neuronal or synaptic degeneration in nondemented elderly persons. |
1999-06-04 |
2023-08-12 |
human |
| B R Leavitt, C S Hernit-Grant, J D Mackli. Mature astrocytes transform into transitional radial glia within adult mouse neocortex that supports directed migration of transplanted immature neurons. Experimental neurology. vol 157. issue 1. 1999-06-03. PMID:10222107. |
mature astrocytes transform into transitional radial glia within adult mouse neocortex that supports directed migration of transplanted immature neurons. |
1999-06-03 |
2023-08-12 |
mouse |
| Y Kamei, N Inagaki, M Nishizawa, O Tsutsumi, Y Taketani, M Inagak. Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia. vol 23. issue 3. 1998-08-27. PMID:9633804. |
in the neocortex, mainly radial glia in the ventricular zone, but not their progeny, underwent cell division. |
1998-08-27 |
2023-08-12 |
rat |
| Y Kamei, N Inagaki, M Nishizawa, O Tsutsumi, Y Taketani, M Inagak. Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia. vol 23. issue 3. 1998-08-27. PMID:9633804. |
radial glia in the neocortex divided horizontally, obliquely, and vertically against the ventricular surface. |
1998-08-27 |
2023-08-12 |
rat |
| Y Kamei, N Inagaki, M Nishizawa, O Tsutsumi, Y Taketani, M Inagak. Visualization of mitotic radial glial lineage cells in the developing rat brain by Cdc2 kinase-phosphorylated vimentin. Glia. vol 23. issue 3. 1998-08-27. PMID:9633804. |
thus, the monoclonal antibody 4a4 provides an useful tool to label mitotic glia in the developing brain and revealed different patterns of gliogenesis in the neocortex and cerebellum. |
1998-08-27 |
2023-08-12 |
rat |
| S Ciaroni, O Buffi, P Ambrogini, T Cecchini, P Del Grand. Neuron and glial cells in neocortex after methylazoxymethanol treatment in early development. Mechanisms of ageing and development. vol 100. issue 3. 1998-06-04. PMID:9578117. |
in the neocortex of mam-mice at this numerical uniformity of glial cell density, did not correspond to a similar proportional composition: the frequency of the astrocytes is lower, adapting to the decreased neuron density; the greater oligodendrocyte percentage may be related to disturbed layering and to the hyperinnervation of the hypoplastic cortex; the microglia shows a trend similar to that of the controls. |
1998-06-04 |
2023-08-12 |
mouse |
| E Y Snyder, C Yoon, J D Flax, J D Mackli. Multipotent neural precursors can differentiate toward replacement of neurons undergoing targeted apoptotic degeneration in adult mouse neocortex. Proceedings of the National Academy of Sciences of the United States of America. vol 94. issue 21. 1997-11-24. PMID:9326667. |
in intact and kainic acid-lesioned control adult neocortex, transplanted precursors differentiated exclusively into glia. |
1997-11-24 |
2023-08-12 |
mouse |