| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mirko Lehmann, Thomas Plieger, Martin Reuter, UlrichEttinge. Insights into the molecular genetic basis of individual differences in metacognition. Physiology & behavior vol issue 2023 36870383 |
here, an initial step toward resolving this issue was undertaken by investigating functional polymorphisms from three genes of the dopaminergic or serotonergic systems (drd4, comt, and 5-httlpr) in relation to behaviorally assessed metacognition in six paradigms across three cognitive domains. |
2023-03-04 |
2023-03-06 |
Not clear |
| Gerly Tamm, Kairi Kreegipuu, Jaanus Harr. Platelet MAO activity and COMT Val158Met genotype interaction predicts visual working memory updating efficiency. Behavioural brain research vol 407 issue 2021 33745984 |
platelet monoamine oxidase (mao) has been used as a marker for central serotonergic capacity, and catechol-o-methyltransferase (comt) as a marker for central dopaminergic capacity. |
2021-09-02 |
2023-01-26 |
human |
| R Slopie\\xc5\\x84, A R\\xc3\\xb3zycka, A Slopie\\xc5\\x84, M Pawlak, A Warenik-Szymankiewicz, S Sajdak, P Jagodzi\\xc5\\x84sk. The genetic background of climacteric symptoms in women during menopause. Clinical and experimental obstetrics & gynecology vol 43 issue 4 2018 29734534 |
among the candidate genes in the aetiology of depression the following were selected for the research: the serotonergic system receptor genes: 5htr2a, 5htr1b, 5htr2c, tph 1, tph2, and mao-a; the genes of noradrenergic and dopaminergic systems (comt, net), the genes of the gabaergic (gabrbl) system, a gene of the estrogen receptor (esr1), and the genes of the enzymes crucial in the methyl cycle (mthrf, mtr, and mthfd1). |
2018-06-20 |
2023-01-26 |
human |
| Xiaoxue Gao, Jinting Liu, Pingyuan Gong, Junhui Wang, Wan Fang, Hongming Yan, Lusha Zhu, Xiaolin Zho. Identifying new susceptibility genes on dopaminergic and serotonergic pathways for the framing effect in decision-making. Social cognitive and affective neuroscience vol 12 issue 9 2018 28431168 |
this effect has been found to be modulated by the serotonin transporter gene (slc6a4) and the catechol-o-methyltransferase gene (comt) polymorphisms, which are on the dopaminergic and serotonergic pathways and which are associated with affective processing. |
2018-05-24 |
2023-01-26 |
human |
| Vjekoslav Peitl, Mario \\xc5\\xa0tefanovi\\xc4\\x87, Dalibor Karlovi\\xc4\\x8. Depressive symptoms in schizophrenia and dopamine and serotonin gene polymorphisms. Progress in neuro-psychopharmacology & biological psychiatry vol 77 issue 2018 28416295 |
as impaired serotonergic and dopaminergic neurotransmission is implicated in the pathogenesis of depression and schizophrenia this study sought to investigate the putative association between several functional gene polymorphisms (sert 5-httlpr, mao-a vntr, comt val158met and dat vntr) and schizophrenia. |
2018-03-05 |
2023-01-26 |
human |
| Lindsay N Douglas, Austen B McGuire, Ann M Manzardo, Merlin G Butle. High-resolution chromosome ideogram representation of recognized genes for bipolar disorder. Gene vol 586 issue 1 2017 27063557 |
the identified genes impacted a broad range of biological pathways and processes including cellular signaling pathways particularly camp and calcium (e.g., cacna1c, camk2a, camk2d, adcy1, adcy2); glutamatergic (e.g., grik1, grm3, grm7), dopaminergic (e.g., drd2, drd4, comt, maoa) and serotonergic (e.g., htr1a, htr2a, htr3b) neurotransmission; molecular transporters (e.g., slc39a3, slc6a3, slc8a1); and neuronal growth (e.g., bdnf, igfbp1, nrg1, nrg3). |
2017-01-03 |
2023-01-25 |
human |
| Z Naumovska, A K Nestorovska, A Filipce, Z Sterjev, K Brezovska, A Dimovski, L J Suturkov. Pharmacogenetics and antipsychotic treatment response. Prilozi (Makedonska akademija na naukite i umetnostite. Oddelenie za medicinski nauki) vol 36 issue 1 2016 26076775 |
it highlights the most important findings about the impact of functional polymorphisms in genes coding the cyp450 metabolizing enzymes, abcb1 transporter gene, dopaminergic and serotonergic drug targets (drd2, drd3, drd4, 5-ht1, 5ht-2a, 5ht-2c, 5ht6) as well as genes responsible for metabolism of neurotransmitters and g signalling pathways (5-httlpr, bdnf, comt, rgs4) and points their role as potential biomarkers in everyday clinical practice. |
2016-07-15 |
2023-01-25 |
Not clear |
| A E Gareeva, K O Kinyasheva, D Yu Galaktionova, E T Sabirov, R G Valinourov, A V Chudinov, A S Zasedatelev, T V Nasedkina, E K Khusnutdinov. [Brain neurotransmitter systems gene Polymorphism: the Search for pharmacogenetic markers of efficacy of haloperidol in Russians and Tatars]. Molekuliarnaia biologiia vol 49 issue 6 2016 26710776 |
in this paper, we analyzed the association of nine polymorphic variants of five genes of dopaminergic and serotonergic systems drd4, htr2a, tph1, slc18a1, comt in russian and tatars patients living in the republic of bashkortostan (rb) with the efficiency of a typical antipsychotic haloperidol on the scale of positive and negative systems of panss. |
2016-02-23 |
2023-01-25 |
Not clear |
| Pia Baldinger, Andreas Hahn, Markus Mitterhauser, Georg S Kranz, Marion Friedl, Wolfgang Wadsak, Christoph Kraus, Johanna Ungersb\\xc3\\xb6ck, Annette Hartmann, Ina Giegling, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Impact of COMT genotype on serotonin-1A receptor binding investigated with PET. Brain structure & function vol 219 issue 6 2015 23928748 |
in light of the frequently reported alterations of 5-ht1a binding in anxiety and mood disorders, this study proposes a potential implication of the comt genotype, more specifically the val158met polymorphism, via modulation of the serotonergic neurotransmission. |
2015-07-07 |
2023-01-25 |
human |
| Pia Baldinger, Andreas Hahn, Markus Mitterhauser, Georg S Kranz, Marion Friedl, Wolfgang Wadsak, Christoph Kraus, Johanna Ungersb\\xc3\\xb6ck, Annette Hartmann, Ina Giegling, Dan Rujescu, Siegfried Kasper, Rupert Lanzenberge. Impact of COMT genotype on serotonin-1A receptor binding investigated with PET. Brain structure & function vol 219 issue 6 2015 23928748 |
given the close interactions between serotonergic and dopaminergic neurotransmission, we investigated whether a common single-nucleotide-polymorphism of the catechol-o-methyltransferase (comt) gene (val158met or rs4680) coding for a key enzyme of the dopamine network that is associated with the pathogenesis of mood disorders and antidepressant treatment response, directly affects 5-ht1a receptor binding potential. |
2015-07-07 |
2023-01-25 |
human |
| Edna Gr\\xc3\\xbcnblatt, Tobias U Hauser, Susanne Walitz. Imaging genetics in obsessive-compulsive disorder: linking genetic variations to alterations in neuroimaging. Progress in neurobiology vol 121 issue 2015 25046835 |
the most promising findings of this systematic review point to the involvement of variants in genes involved in the serotonergic (5-httlpr, htr2a), dopaminergic (comt, dat), and glutamatergic (slc1a1, sapap) systems. |
2015-06-02 |
2023-01-25 |
Not clear |
| Sarah Wilker, Thomas Elbert, Iris-Tatjana Kolass. The downside of strong emotional memories: how human memory-related genes influence the risk for posttraumatic stress disorder--a selective review. Neurobiology of learning and memory vol 112 issue 2015 24012801 |
here, we focus on genes involved in noradrenergic (adra2b), serotonergic (slc6a4), and dopaminergic signaling (comt) as well as in the molecular cascades of memory formation (prkca and wwc1). |
2015-02-09 |
2023-01-25 |
human |
| Marta Rodriguez-Arias, Francisco Navarrete, Manuel Daza-Losada, Daniela Navarro, Mar\\xc3\\xada A Aguilar, Pere Berbel, Jos\\xc3\\xa9 Mi\\xc3\\xb1arro, Jorge Manzanare. CB1 cannabinoid receptor-mediated aggressive behavior. Neuropharmacology vol 75 issue 2014 23916480 |
gene expression analyses of monoaminooxidase-a (mao-a), catechol-o-methyl-transferase (comt), 5-hydroxytriptamine transporter (5-htt) and 5-ht1b serotonergic receptor (5ht1br) in the median and dorsal raphe nuclei (mnr and dr, respectively) and in the amygdala (amy) were performed by real time-pcr. |
2014-08-19 |
2023-01-25 |
mouse |
| I Heitland, R S Oosting, J M P Baas, S A A Massar, J L Kenemans, K B E B\\xc3\\xb6cke. Genetic polymorphisms of the dopamine and serotonin systems modulate the neurophysiological response to feedback and risk taking in healthy humans. Cognitive, affective & behavioral neuroscience vol 12 issue 4 2013 22810728 |
here, we studied the effects of dopaminergic (dopamine transporter [dat1], catecholamine-o-methyltransferase val158met [comt]) and serotonergic (serotonin transporter [5httlpr]) polymorphisms on risk taking and brain responses following feedback in 60 healthy female subjects. |
2013-05-03 |
2023-01-25 |
human |
| Emrah Cayla. Biochemical and genetic analyses of childhood attention deficit/hyperactivity disorder. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics vol 159B issue 6 2013 22825876 |
to date, these studies have reported substantial evidence implicating several genes (dopaminergic: drd4, dat1, drd5, comt; noradrenergic: dbh, adra2a; serotonergic: 5-htt, htr1b, htr2a; cholinergic: chrna4, and central nervous system development pathway: snap25, bdnf) in the etiology of adhd. |
2013-04-09 |
2023-01-25 |
Not clear |
| Gabor Varga, Anna Szekely, Peter Antal, Peter Sarkozy, Zsofia Nemoda, Zsolt Demetrovics, Maria Sasvari-Szekel. Additive effects of serotonergic and dopaminergic polymorphisms on trait impulsivity. American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics vol 159B issue 3 2012 22259185 |
here we report an association study of both dopaminergic (comt rs4680, drd4 48\xe2\x80\x89bp vntr, drd2/ankk1 rs1800497) and serotonergic (htr1a rs6925, htr1b rs13212041, slc6a4 5-httlpr) gene polymorphisms and trait impulsivity assessed with the barratt impulsiveness scale (bis-11) in a sample of 687 caucasian young adults. |
2012-10-05 |
2023-01-25 |
Not clear |
| Kenneth Blum, Yijun Liu, Richard Shriner, Mark S Gol. Reward circuitry dopaminergic activation regulates food and drug craving behavior. Current pharmaceutical design vol 17 issue 12 2011 21492092 |
individuals possessing a paucity of serotonergic and/or dopaminergic receptors and an increased rate of synaptic dopamine catabolism, due to high catabolic genotype of the comt gene, are predisposed to self-medicating any substance or behavior that will activate dopamine release including alcohol, opiates, psychostimulants, nicotine, glucose, gambling, sex, and even excessive internet gaming, among others. |
2011-08-30 |
2023-01-25 |
human |
| Katharina Domschke, J\\xc3\\xbcrgen Decker. Genetics. Current topics in behavioral neurosciences vol 2 issue 2011 21309106 |
a particular focus will be on the most robust findings in panic disorder to date in the serotonergic, noradrenergic, and dopaminergic system, such as the catechol-o-methyltransferase (comt) gene. |
2011-03-07 |
2023-01-25 |
Not clear |
| A Heck, R Lieb, A Ellgas, H Pfister, S Lucae, D Roeske, B P\\xc3\\xbctz, B M\\xc3\\xbcller-Myhsok, M Uhr, F Holsboer, M Isin. Investigation of 17 candidate genes for personality traits confirms effects of the HTR2A gene on novelty seeking. Genes, brain, and behavior vol 8 issue 4 2009 19566713 |
to overcome this limitation, we performed an extended genetic association study analyzing 17 serotonergic (slc6a4, htr1a, htr1b, htr2a, htr2c, htr3a, htr6, maoa, tph1, tph2) and dopaminergic genes (slc6a3, drd2, drd3, drd4, comt, maoa, th, dbh), which have been previously reported to be implicated with personality traits. |
2009-09-11 |
2023-01-25 |
Not clear |
| Johanna Hilli, Tuija Heikkinen, Riikka Rontu, Terho Lehtim\\xc3\\xa4ki, Ikuko Kishida, Eleni Aklillu, Leif Bertilsson, Tero Vahlberg, Kari Lain. MAO-A and COMT genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to SSRIs. European neuropsychopharmacology : the journal of the European College of Neuropsychopharmacology vol 19 issue 5 2009 19223155 |
mao-a and comt genotypes as possible regulators of perinatal serotonergic symptoms after in utero exposure to ssris. |
2009-06-05 |
2023-01-25 |
Not clear |