| Reference |
Sentence |
Publish Date |
Extraction Date |
Species |
| Zhenhua Yan, Yufang Chen, Xiadong Zhang, Guanghua L. The metabolites could not be ignored: A comparative study of the metabolite norfluoxetine with its parent fluoxetine on zebrafish (Danio rerio). Aquatic toxicology (Amsterdam, Netherlands) vol 257 issue 2023 36870174 |
the functional genes related to serotonergic process (5-ht1aa, 5-ht2c, slc6a4b, and vmat), early growth (egr4), and circadian rhythm (per2) were downregulated by both the norfluoxetine and fluoxetine, indicative of the same mode-of-action of norfluoxetine with its parent in these functions. |
2023-03-04 |
2023-03-06 |
zebrafish |
| Ria Gupta, Sidharth Mehan, Swesha Chhabra, Aditi Giri, Kajal Sherawa. Role of Sonic Hedgehog Signaling Activation in the Prevention of Neurological Abnormalities Associated with Obsessive-Compulsive Disorder. Neurotoxicity research vol issue 2022 36272053 |
the shh ligand activates two main transcriptional factors known as foxa2 and nkx2.2, which again activates another transcriptional factor, gata (gata2 and gata3), in post mitotic precursor cells of serotonergic neurons-following increased expression of pet-1 and lmx1b after gata regulates the expression of many serotonergic enzymes such as tph2, sert, vmat, slc6a4, htr1a, htr1b (serotonin receptor enzymes), and mao that regulate and control the release of serotonin and maintain their neuronal identity after their maturation. |
2022-10-22 |
2023-01-30 |
Not clear |
| V Cunha, P Rodrigues, M M Santos, P Moradas-Ferreira, M Ferreir. Fluoxetine modulates the transcription of genes involved in serotonin, dopamine and adrenergic signalling in zebrafish embryos. Chemosphere vol 191 issue 2018 29145140 |
the transcription levels of serotonergic and dopaminergic transporters (sert and dat) and vmat were down-regulated at environmentally relevant concentration (0.0015\xc2\xa0\xce\xbcm). |
2018-01-10 |
2023-01-26 |
zebrafish |
| Wei Zhang, Sungwon Kim, Robert Settlage, Wyatt McMahon, Lindsay H Sumners, Paul B Siegel, Benjamin J Dorshorst, Mark A Cline, Elizabeth R Gilber. Hypothalamic differences in expression of genes involved in monoamine synthesis and signaling pathways after insulin injection in chickens from lines selected for high and low body weight. Neurogenetics vol 16 issue 2 2015 25582322 |
four were located in genes encoding enzymes associated with serotonergic and dopaminergic pathways, such as ddc, th, and solute carrier family 18, member 2 (vmat). |
2015-11-25 |
2023-01-25 |
chicken |
| H-Y Chang, A Grygoruk, E S Brooks, L C Ackerson, N T Maidment, R J Bainton, D E Krant. Overexpression of the Drosophila vesicular monoamine transporter increases motor activity and courtship but decreases the behavioral response to cocaine. Molecular psychiatry vol 11 issue 1 2006 16189511 |
we show that a drosophila isoform of vmat (dvmat-a) is expressed in both dopaminergic and serotonergic neurons in the adult drosophila brain. |
2006-04-17 |
2023-01-24 |
drosophila_melanogaster |