All Relations between endogenous cannabinoid system and cannabinoids

Reference Sentence Publish Date Extraction Date Species
Monika Vidlarova, Emil Berta, Petr Prasil, Andrea Prokopova, Sona Gurska, Marta Khoylou, Alona Rehulkova, Pavla Kourilova, Josef Chudacek, Marek Szkorupa, Jiri Klein, Jozef Skarda, Josef Srovnal, Marian Hajduc. Cannabinoid receptor 2 expression in early-stage non-small cell lung cancers identifies patients with good prognosis and longer survival. Translational lung cancer research vol 11 issue 10 2022 36386452 since the endogenous cannabinoid system is involved in both carcinogenesis and anticancer immune defense, we hypothesized that tumor tissue expression of cannabinoid 1 and 2 receptors (cb1 and cb2) may affect survival. 2022-11-17 2022-11-21 Not clear
Wujood Khayat, Christian Lehman. The Endocannabinoid System: A Potential Therapeutic Target for Coagulopathies. Metabolites vol 12 issue 6 2022 35736474 a growing body of evidence has demonstrated blood coagulation abnormalities in association with cannabinoid use, suggesting the involvement of the endogenous cannabinoid system (ecs) in modulating blood coagulation. 2022-06-23 2022-06-27 Not clear
Courtney A Bouchet, Amy J Eshleman, Aaron Janowsky, Susan L Ingra. Persistent Inflammation Induces Desensitization of the Presynaptic Cannabinoid 1 Receptor in the Ventrolateral Periaqueductal Gray. FASEB journal : official publication of the Federation of American Societies for Experimental Biology vol 36 Suppl 1 issue 2022 35552994 the cannabinoid system is highly plastic and sensitive to environmental perturbations, often leading to downregulation of the cannabinoid 1 receptor (cb1r). 2022-05-13 2022-06-13 Not clear
Joshua Lott, Emily M Jutkiewicz, Manojkumar A Puthenveed. The Synthetic Cannabinoid WIN55,212-2 Can Disrupt the Golgi Apparatus Independent of Cannabinoid Receptor-1. Molecular pharmacology vol 101 issue 5 2022 35236771 significance statement: the synthetic cannabinoid win55,212-2 (win), widely used to investigate the cannabinoid system, also shows unique broader effects at cellular and organismal levels compared to endogenous cannabinoids. 2022-04-12 2022-06-13 Not clear
Jiacheng Du, Menglei Xu, Fanchen Kong, Pengfei Zhu, Yubo Mao, Yijie Liu, Hong Zhou, Zhongchen Dong, Zilin Yu, Tong Du, Ye Gu, Xiexing Wu, Dechun Geng, Haiqing Ma. CB2R Attenuates Intervertebral Disc Degeneration by Delaying Nucleus Pulposus Cell Senescence through AMPK/GSK3\\xce\\xb2 Pathway. Aging and disease vol 13 issue 2 2022 35371598 the cannabinoid type 2 receptor (cb2r) is a member of the cannabinoid system and plays an important role in antioxidative stress, anti-inflammatory and antisenescence activities. 2022-04-04 2022-04-14 Not clear
Mengya Wang, Huayuan Liu, Zegang M. Roles of the Cannabinoid System in the Basal Ganglia in Parkinson's Disease. Frontiers in cellular neuroscience vol 16 issue 2022 35264932 here, we have described the function of the cannabinoid system in the basal ganglia and its association with pd in three parts (ecbs, cannabinoid receptors, and factors regulating the cannabinoid metabolism) and summarized the mechanisms of action related to the cannabinoid analogs currently aimed at treating pd. 2022-03-10 2022-04-14 Not clear
Luke J Ney, Kevin M Crombie, Leah M Mayo, Kim L Felmingham, Tim Bowser, Allison Matthew. Translation of animal endocannabinoid models of PTSD mechanisms to humans: Where to next? Neuroscience and biobehavioral reviews vol 132 issue 2021 34838529 here we review how human paradigms can successfully translate animal findings to human subjects, with the view that substantially increased insight into the effect of endocannabinoid signalling on stress responding, emotional and intrusive memories, and fear extinction can be gained using modern paradigms and methods for assessing the state of the endocannabinoid system in ptsd. 2022-02-04 2022-01-13 Not clear
Rachel Kelly, Alexis-Pierre Bemelmans, Charl\\xc3\\xa8ne Jos\\xc3\\xa9phine, Emmanuel Brouillet, Declan P McKernan, Eil\\xc3\\xads Dow. Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of \\xce\\xb1-Synuclein in the Rat Brain. Molecules (Basel, Switzerland) vol 27 issue 2 2022 35056822 cannabinoids are being investigated as potential therapies for parkinson's disease from numerous aspects, but still little is known about the links between the cannabinoid system and the pathogenic \xce\xb1-synuclein protein; understanding these links will be necessary if cannabinoid therapies are to reach the clinic in the future. 2022-01-28 2022-01-27 Not clear
Wanhao Yan, Le Li, Lihua Ge, Fengqiu Zhang, Zhipeng Fan, Lei H. The cannabinoid receptor I (CB1) enhanced the osteogenic differentiation of BMSCs by rescue impaired mitochondrial metabolism function under inflammatory condition. Stem cell research & therapy vol 13 issue 1 2022 35063024 the cannabinoid receptor i (cb1) is the main effector of the endogenous cannabinoid system (ecs), and our previous study verified that cb1 could enhance the osteo/dentinogenic differentiation of dental mscs, which might be a target for alveolar bone regeneration. 2022-01-28 2022-01-27 Not clear
Wanhao Yan, Le Li, Lihua Ge, Fengqiu Zhang, Zhipeng Fan, Lei H. The cannabinoid receptor I (CB1) enhanced the osteogenic differentiation of BMSCs by rescue impaired mitochondrial metabolism function under inflammatory condition. Stem cell research & therapy vol 13 issue 1 2022 35063024 the cannabinoid receptor i (cb1) is the main effector of the endogenous cannabinoid system (ecs), and our previous study verified that cb1 could enhance the osteo/dentinogenic differentiation of dental mscs, which might be a target for alveolar bone regeneration. 2022-01-22 2022-01-27 Not clear
Rachel Kelly, Alexis-Pierre Bemelmans, Charl\\xc3\\xa8ne Jos\\xc3\\xa9phine, Emmanuel Brouillet, Declan P McKernan, Eil\\xc3\\xads Dow. Time-Course of Alterations in the Endocannabinoid System after Viral-Mediated Overexpression of \\xce\\xb1-Synuclein in the Rat Brain. Molecules (Basel, Switzerland) vol 27 issue 2 2022 35056822 cannabinoids are being investigated as potential therapies for parkinson's disease from numerous aspects, but still little is known about the links between the cannabinoid system and the pathogenic \xce\xb1-synuclein protein; understanding these links will be necessary if cannabinoid therapies are to reach the clinic in the future. 2022-01-21 2022-01-27 Not clear
David De Sa Nogueira, Romain Bourdy, Rafael Alcala-Vida, Dominique Filliol, Virginie Andry, Yannick Goumon, Jean Zwiller, Pascal Romieu, Karine Merienne, Mary C Olmstead, Katia Befor. Hippocampal Cannabinoid 1 Receptors Are Modulated Following Cocaine Self-administration in Male Rats. Molecular neurobiology vol issue 2022 35032317 the endogenous cannabinoid system may play a role in this process in that cannabinoid mechanisms modulate drug reward and contribute to cocaine-induced neural adaptations. 2022-01-15 2022-01-27 Not clear
Luke J Ney, Kevin M Crombie, Leah M Mayo, Kim L Felmingham, Tim Bowser, Allison Matthew. Translation of animal endocannabinoid models of PTSD mechanisms to humans: Where to next? Neuroscience and biobehavioral reviews vol 132 issue 2021 34838529 here we review how human paradigms can successfully translate animal findings to human subjects, with the view that substantially increased insight into the effect of endocannabinoid signalling on stress responding, emotional and intrusive memories, and fear extinction can be gained using modern paradigms and methods for assessing the state of the endocannabinoid system in ptsd. 2021-12-11 2022-01-13 Not clear
Sebastiaan Dalle, Katrien Kopp. Cannabinoid receptor 1 expression is higher in muscle of old vs. young males, and increases upon resistance exercise in older adults. Scientific reports vol 11 issue 1 2021 34526596 here, we explored the role of the cannabinoid system in muscle plasticity through the expression of muscle cannabinoid receptors (cbs) in young and old humans. 2021-12-07 2022-01-13 Not clear
Deepthi Rapaka, Veera Raghavulu Bitra, Siva Reddy Challa, Paul C Adiukw. Potentiation of microglial endocannabinoid signaling alleviates neuroinflammation in Alzheimer's disease. Neuropeptides vol 90 issue 2021 34508923 the activation of cannabinoid receptors/ cannabinoid system modulates inflammatory responses. 2021-11-22 2022-01-13 Not clear
Ondine Lucaciu, Ovidiu Aghiorghiesei, Nausica Bianca Petrescu, Ioana Codruta Mirica, Horea Rare\\xc8\\x99 Ciprian Benea, Drago\\xc8\\x99 Apost. In quest of a new therapeutic approach in COVID-19: the endocannabinoid system. Drug metabolism reviews vol 53 issue 4 2021 33683968 although the cannabinoid system has many mechanisms to provide certain benefits in the treatment of sars-cov-2 infected patients, research in this field is needed for a better understanding of the cannabinoid impact in this situation. 2021-11-15 2022-01-13 Not clear
Mashal Ahmed, Isabelle Boileau, Bernard Le Foll, Andre F Carvalho, Stefan Kloibe. The endocannabinoid system in social anxiety disorder: from pathophysiology to novel therapeutics. Revista brasileira de psiquiatria (Sao Paulo, Brazil : 1999) vol issue 2021 34468550 emerging evidence suggests that the endogenous cannabinoid system, also referred to as the endocannabinoid system (ecs), could play a potential role in the pathophysiology of sad. 2021-09-01 2022-01-14 Not clear
Andrew J Kesner, David M Lovinge. Cannabis use, abuse, and withdrawal: Cannabinergic mechanisms, clinical, and preclinical findings. Journal of neurochemistry vol 157 issue 5 2021 33891706 one of the main components being central action on the cannabinoid type-one receptor and downstream intracellular signaling related to the endogenous cannabinoid system. 2021-08-24 2022-01-13 Not clear
Michelle A Tucci, Yilianys Pride, Suzanne Strickland, Susanna M Salazar Marocho, Ramon J Jackson, Joshua R Jefferson, Alejandro R Chade, Raymond J Grill, Bernadette E Grayso. Delayed Systemic Treatment with Cannabinoid Receptor 2 Agonist Mitigates Spinal Cord Injury-Induced Osteoporosis More Than Acute Treatment Directly after Injury. Neurotrauma reports vol 2 issue 1 2021 34223557 the cannabinoid system modulation of bone metabolism through cannabinoid 1/2 (cb1/2) has been of increasing interest for the preservation of bone mass and density in models of osteoporosis. 2021-08-12 2022-01-13 Not clear
Patricia Rivera, Antonio Vargas, Antoni Pastor, Anna Boronat, Antonio Jes\\xc3\\xbas L\\xc3\\xb3pez-Gambero, Laura S\\xc3\\xa1nchez-Mar\\xc3\\xadn, Dina Medina-Vera, Antonia Serrano, Francisco Javier Pav\\xc3\\xb3n, Rafael de la Torre, Ekaitz Agirregoitia, Mar\\xc3\\xada Isabel Lucena, Fernando Rodr\\xc3\\xadguez de Fonseca, Juan Decara, Juan Su\\xc3\\xa1re. Differential hepatoprotective role of the cannabinoid CB British journal of pharmacology vol 177 issue 14 2021 32167157 differential hepatoprotective role of the cannabinoid cb protective mechanisms of the endogenous cannabinoid system against drug-induced liver injury (dili) are actively being investigated regarding the differential regulatory role of the cannabinoid cb 2021-06-21 2022-01-13 Not clear
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