| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aaron S Helle. Adding to the neuroimmune network model: A commentary on Nusslock et al. (2024). Journal of child psychology and psychiatry, and allied disciplines. 2024-03-16. PMID:38491727. |
one principal circuit includes the amygdala and prefrontal cortex and is proposed to be involved in threat detection. |
2024-03-16 |
2024-03-19 |
Not clear |
| Michael T Liuzzi, Farah Harb, Kevin Petranu, Ashley A Huggins, E Kate Webb, Jacklynn M Fitzgerald, Jessica L Krukowski, Tara A Miskovich, Terri A deRoon-Cassini, Christine L Larso. The dichotomy of threat and deprivation as subtypes of childhood maltreatment: Differential functional connectivity patterns of threat and reward circuits in an adult trauma sample. Biological psychiatry. Cognitive neuroscience and neuroimaging. 2023-10-23. PMID:37871776. |
childhood maltreatment is associated with reduced activation of the nucleus accumbens, a central region in the reward network, and overactivity in the amygdala, a key region in threat processing. |
2023-10-23 |
2023-11-08 |
Not clear |
| Melek Hande Bulut Demir, Rahime Kaya, Ozgun Ozalay, Damla Isman Haznedaroglu, Yigit Erdogan, Omer Kitis, Tezan Bildik, Ali Saffet Gonul, Mehmet Cagdas Eke. The effects of sexual abuse on female adolescent brain structures. Scandinavian journal of child and adolescent psychiatry and psychology. vol 11. issue 1. 2023-10-11. PMID:37818143. |
we hypothesized that children with sa would have a thinner pfc with larger amygdala and hippocampus that lead to aberrations in threat detection, orientation and response circuit; that would be highly adaptive in a dangerous environment in the short term. |
2023-10-11 |
2023-10-15 |
Not clear |
| Katarina Forkmann, Katja Wiech, Katharina Schmidt, Julia Schmid-Köhler, Ulrike Binge. Neural underpinnings of preferential pain learning and the modulatory role of fear. Cerebral cortex (New York, N.Y. : 1991). 2023-07-06. PMID:37408110. |
these behavioral findings were paralleled by activation of brain regions implicated in threat processing (insula, amygdala) and personal significance (ventromedial prefrontal cortex). |
2023-07-06 |
2023-08-14 |
human |
| Jianjun Zhu, Carl M Anderson, Kyoko Ohashi, Alaptagin Khan, Martin H Teiche. Potential sensitive period effects of maltreatment on amygdala, hippocampal and cortical response to threat. Molecular psychiatry. 2023-03-03. PMID:36869224. |
bold activation fmri response to threatening versus neutral facial images was assessed in key components of the threat detection system (i.e., amygdala, hippocampus, anterior cingulate, inferior frontal gyrus and ventromedial and dorsomedial prefrontal cortices) in 202 healthy, unmedicated, participants (84 m/118 f, 23.2 ± 1.7 years old). |
2023-03-03 |
2023-08-14 |
human |
| Wen Li, Andreas Kei. Sensing fear: fast and precise threat evaluation in human sensory cortex. Trends in cognitive sciences. 2023-02-02. PMID:36732175. |
animal models of threat processing have evolved beyond the amygdala to incorporate a distributed neural network. |
2023-02-02 |
2023-08-14 |
human |
| Melanie Porter, Polina Gavria, Jessica Reeve, Michael Green, Sarah Baracz, Adriana Rossi, Kelsie Boulto. Neuroanatomical correlates of social approach in Williams Syndrome and down syndrome. Neuropsychologia. 2022-09-11. PMID:36088994. |
two brain regions - the amygdala and the orbitofrontal cortex (ofc) - have been implicated in driving this hypersociability in ws, and in the general population and have associations with emotional evaluation, threat detection and social motivation. |
2022-09-11 |
2023-08-14 |
Not clear |
| Katherine Packard, Maya Openda. Rodent models of early adversity: Impacts on developing social behavior circuitry and clinical implications. Frontiers in behavioral neuroscience. vol 16. 2022-08-22. PMID:35990728. |
we next explore these circuits underlying perturbed social functioning with focus on dopamine (da) and its role in regions implicated in social and threat processing such as the prefrontal cortex (pfc), basolateral amygdala (bla) and the lateral habenula (lhb). |
2022-08-22 |
2023-08-14 |
human |
| Neeti D Mehta, Jennifer S Stevens, Zhihao Li, Negar Fani, Charles F Gillespie, Meghna Ravi, Vasiliki Michopoulos, Jennifer C Felge. Inflammation, Amygdala-Ventromedial Prefrontal Functional Connectivity and Symptoms of Anxiety and PTSD in African American Women Recruited from an Inner-City Hospital: Preliminary Results. Brain, behavior, and immunity. 2022-06-30. PMID:35772683. |
inflammatory stimuli have been shown to impact brain regions involved in threat detection and emotional processing including amygdala and ventromedial prefrontal cortex (vmpfc), and to increase anxiety. |
2022-06-30 |
2023-08-14 |
Not clear |
| Aline W de Borst, Beatrice de Gelde. Threat Detection in Nearby Space Mobilizes Human Ventral Premotor Cortex, Intraparietal Sulcus, and Amygdala. Brain sciences. vol 12. issue 3. 2022-03-25. PMID:35326349. |
threat detection in nearby space mobilizes human ventral premotor cortex, intraparietal sulcus, and amygdala. |
2022-03-25 |
2023-08-13 |
human |
| Mikio Inagaki, Ken-Ichi Inoue, Soshi Tanabe, Kei Kimura, Masahiko Takada, Ichiro Fujit. Rapid processing of threatening faces in the amygdala of nonhuman primates: subcortical inputs and dual roles. Cerebral cortex (New York, N.Y. : 1991). 2022-03-24. PMID:35323915. |
we suggest that the early amygdala responses originating from the colliculo-pulvino-amygdalar pathway play dual roles in threat detection. |
2022-03-24 |
2023-08-13 |
monkey |
| Xianyang Gan, Xinqi Zhou, Jialin Li, Guojuan Jiao, Xi Jiang, Bharat Biswal, Shuxia Yao, Benjamin Klugah-Brown, Benjamin Becke. Common and distinct neurofunctional representations of core and social disgust in the brain: Coordinate-based and network meta-analyses. Neuroscience and biobehavioral reviews. 2022-02-05. PMID:35122784. |
core disgust evoked stronger reactivity in left-lateralized threat detection and defensive response network including amygdala, occipital and frontal regions, while social disgust engaged a right-lateralized superior temporal-frontal network engaged in social cognition. |
2022-02-05 |
2023-08-13 |
Not clear |
| M Alexandra Kredlow, Robert J Fenster, Emma S Laurent, Kerry J Ressler, Elizabeth A Phelp. Prefrontal cortex, amygdala, and threat processing: implications for PTSD. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 47. issue 1. 2021-12-12. PMID:34545196. |
prefrontal cortex, amygdala, and threat processing: implications for ptsd. |
2021-12-12 |
2023-08-13 |
Not clear |
| Yu-Chun Chen, Chenyi Chen, Róger Marcelo Martínez, Yang-Tang Fan, Chia-Chien Liu, Chin-Yau Chen, Yawei Chen. An amygdala-centered hyper-connectivity signature of threatening face processing predicts anxiety in youths with autism spectrum conditions. Autism research : official journal of the International Society for Autism Research. vol 14. issue 11. 2021-11-29. PMID:34423915. |
lay summary: this study identifies a dissociation of amygdala reactivity dependent on explicit and implicit threat processing. |
2021-11-29 |
2023-08-13 |
Not clear |
| Dana M Smith, Mary M Torregross. Valence encoding in the amygdala influences motivated behavior. Behavioural brain research. vol 411. 2021-10-18. PMID:34051230. |
as many reviews have discussed the amygdala's role in threat processing and fear conditioning, this review will focus on how the amygdala encodes positive valence and the mechanisms that allow it to distinguish between stimuli of positive and negative valence. |
2021-10-18 |
2023-08-13 |
Not clear |
| Karen D Rudolph, Megan M Davis, Haley V Skymba, Haina H Modi, Eva H Telze. Social experience calibrates neural sensitivity to social feedback during adolescence: A functional connectivity approach. Developmental cognitive neuroscience. vol 47. 2021-10-13. PMID:33370666. |
moreover, exposure to adversity predicted stronger fc between the amygdala and regions involved in salience detection, social cognition, and emotional memory (e.g., sgacc, precuneus, lingual gyrus, parahippocampal gyrus) during social threat processing. |
2021-10-13 |
2023-08-13 |
Not clear |
| Erica Bell, Phil Boyce, Richard J Porter, Richard A Bryant, Gin S Malh. Irritability in Mood Disorders: Neurobiological Underpinnings and Implications for Pharmacological Intervention. CNS drugs. vol 35. issue 6. 2021-10-01. PMID:34019255. |
a neurobiological model of irritability posits that, in children and adolescents, it is consequent upon deficits in reward and threat processing, involving regions such as the amygdala and frontal cortices. |
2021-10-01 |
2023-08-13 |
Not clear |
| Shuhei Ueda, Masahito Hosokawa, Koji Arikawa, Kiyofumi Takahashi, Mao Fujiwara, Manami Kakita, Taro Fukada, Hiroaki Koyama, Shin-Ichiro Horigane, Keiichi Itoi, Masaki Kakeyama, Hiroko Matsunaga, Haruko Takeyama, Haruhiko Bito, Sayaka Takemoto-Kimur. Distinctive Regulation of Emotional Behaviors and Fear-Related Gene Expression Responses in Two Extended Amygdala Subnuclei With Similar Molecular Profiles. Frontiers in molecular neuroscience. vol 14. 2021-09-21. PMID:34539345. |
the central nucleus of the amygdala (cea) and the lateral division of the bed nucleus of the stria terminalis (bnst) are the two major nuclei of the central extended amygdala that plays essential roles in threat processing, responsible for emotional states such as fear and anxiety. |
2021-09-21 |
2023-08-13 |
Not clear |
| Shuhei Ueda, Masahito Hosokawa, Koji Arikawa, Kiyofumi Takahashi, Mao Fujiwara, Manami Kakita, Taro Fukada, Hiroaki Koyama, Shin-Ichiro Horigane, Keiichi Itoi, Masaki Kakeyama, Hiroko Matsunaga, Haruko Takeyama, Haruhiko Bito, Sayaka Takemoto-Kimur. Distinctive Regulation of Emotional Behaviors and Fear-Related Gene Expression Responses in Two Extended Amygdala Subnuclei With Similar Molecular Profiles. Frontiers in molecular neuroscience. vol 14. 2021-09-21. PMID:34539345. |
these findings provide novel insights into the molecular makeup and differential engagement of distinct subnuclei of the extended amygdala, critical for regulation of threat processing. |
2021-09-21 |
2023-08-13 |
Not clear |
| Robert H Pietrzak, Yiyun Huang, Stefani Corsi-Travali, Ming-Qiang Zheng, Shu-Fei Lin, Shannan Henry, Marc N Potenza, Daniele Piomelli, Richard E Carson, Alexander Neumeiste. Retraction Note: Cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 45. issue 13. 2021-09-20. PMID:32901117. |
retraction note: cannabinoid type 1 receptor availability in the amygdala mediates threat processing in trauma survivors. |
2021-09-20 |
2023-08-13 |
Not clear |