| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Christopher J Roberts, Francis A Hopp, Quinn H Hogan, Caron Dea. Anandamide in the dorsal periaqueductal gray inhibits sensory input without a correlation to sympathoexcitation. Neurobiology of pain (Cambridge, Mass.). vol 12. 2022-12-19. PMID:36531614. |
the development of chronic pain has been associated with reduced concentrations of the endogenous cannabinoid anandamide (aea) in the midbrain dorsal periaqueductal gray (dpag), and microinjections of synthetic cannabinoids into the dpag are antinociceptive. |
2022-12-19 |
2023-08-14 |
rat |
| Bryony L Winters, Benjamin K Lau, Christopher W Vaugha. Cannabinoids and Opioids Differentially Target Extrinsic and Intrinsic GABAergic Inputs onto the Periaqueductal Grey Descending Pathway. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 42. issue 41. 2022-11-22. PMID:36414010. |
cannabinoids and opioids differentially target extrinsic and intrinsic gabaergic inputs onto the periaqueductal grey descending pathway. |
2022-11-22 |
2023-08-14 |
rat |
| Wen-Qiang Ge, Ou-Yang Zhan-Mu, Chao Chen, Hong Zhang, Xiao-Yu Wang, Xin Liu, Li Li, Yu-Ye Lan, Chen-Nan Li, Jia-Can Sun, Run-Lin Shi, Zi-Yue Dou, Hui-Lin Pan, Hong-Ping Li, Xiang-Hong Jing, Man L. Electroacupuncture reduces chronic itch Frontiers in pharmacology. vol 13. 2022-09-22. PMID:36133809. |
cannabinoid cb1 receptors in the ventrolateral periaqueductal gray (vlpag) mediate the analgesic effect of ea. |
2022-09-22 |
2023-08-14 |
mouse |
| Zhenhua Jiang, Qun Wang, Jianshuai Zhao, Jiajia Wang, You Li, Wei Dai, Xiao Zhang, Zongping Fang, Wugang Hou, Lize Xion. Sex-specific cannabinoid 1 receptors on GABAergic neurons in the ventrolateral periaqueductal gray mediate analgesia in mice. The Journal of comparative neurology. 2022-06-18. PMID:35716006. |
sex-specific cannabinoid 1 receptors on gabaergic neurons in the ventrolateral periaqueductal gray mediate analgesia in mice. |
2022-06-18 |
2023-08-14 |
mouse |
| Courtney A Bouchet, Amy J Eshleman, Aaron Janowsky, Susan L Ingra. Persistent Inflammation Induces Desensitization of the Presynaptic Cannabinoid 1 Receptor in the Ventrolateral Periaqueductal Gray. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 36 Suppl 1. 2022-05-13. PMID:35552994. |
persistent inflammation induces desensitization of the presynaptic cannabinoid 1 receptor in the ventrolateral periaqueductal gray. |
2022-05-13 |
2023-08-13 |
rat |
| Alvaro Llorente-Berzal, Fiona McGowan, Jessica C Gaspar, Kieran Rea, Michelle Roche, David P Fin. Sexually Dimorphic Expression of Fear-conditioned Analgesia in Rats and Associated Alterations in the Endocannabinoid System in the Periaqueductal Grey. Neuroscience. vol 480. 2021-12-10. PMID:34774710. |
sexually dimorphic expression of fear-conditioned analgesia in rats and associated alterations in the endocannabinoid system in the periaqueductal grey. |
2021-12-10 |
2023-08-13 |
rat |
| Alvaro Llorente-Berzal, Fiona McGowan, Jessica C Gaspar, Kieran Rea, Michelle Roche, David P Fin. Sexually Dimorphic Expression of Fear-conditioned Analgesia in Rats and Associated Alterations in the Endocannabinoid System in the Periaqueductal Grey. Neuroscience. vol 480. 2021-12-10. PMID:34774710. |
the endocannabinoid system within the periaqueductal grey (pag) has been implicated in fear-conditioned analgesia (fca), the profound suppression of pain upon re-exposure to a context previously paired with an aversive stimulus. |
2021-12-10 |
2023-08-13 |
rat |
| Ali Mohammad Pourrahimi, Mehdi Abbasnejad, Maryam Raoof, Saeed Esmaeili-Mahani, Razieh Kooshk. The involvement of orexin 1 and cannabinoid 1 receptors within the ventrolateral periaqueductal gray matter in the modulation of migraine-induced anxiety and social behavior deficits of rats. Peptides. vol 146. 2021-11-26. PMID:34560171. |
the involvement of orexin 1 and cannabinoid 1 receptors within the ventrolateral periaqueductal gray matter in the modulation of migraine-induced anxiety and social behavior deficits of rats. |
2021-11-26 |
2023-08-13 |
rat |
| Adrianne R Wilson-Poe, Beth Wiese, Cherkaouia Kibaly, Lindsay Lueptow, Jeniffer Garcia, Preeti Anand, Catherine Cahill, Jose A Moró. Effects of inflammatory pain on CB1 receptor in the midbrain periaqueductal gray. Pain reports. vol 6. issue 1. 2021-09-29. PMID:33693301. |
the periaqueductal gray (pag) mediates the antinociceptive properties of analgesics, including opioids and cannabinoids. |
2021-09-29 |
2023-08-13 |
Not clear |
| Rayssa C Brianis, Rita C Lima, Fabrício A Moreira, Daniele C Aguia. Anti-aversive effect of 2-arachidonoylglycerol in the dorsolateral periaqueductal gray of male rats in contextual fear conditioning and Vogel tests. Behavioural pharmacology. 2021-06-02. PMID:34074811. |
the endocannabinoid system modulates the stress coping strategies in the dorsolateral periaqueductal grey (dlpag). |
2021-06-02 |
2023-08-13 |
rat |
| Aidan Levine, Erika Liktor-Busa, Kelly L Karlage, Luigi Giancotti, Daniela Salvemini, Todd W Vanderah, Tally M Largent-Milne. DAGLα Inhibition as a Non-invasive and Translational Model of Episodic Headache. Frontiers in pharmacology. vol 11. 2021-04-21. PMID:33584293. |
in models of medication overuse headache induced by sustained administration of sumatriptan or morphine, 2-ag levels were selectively depleted in the periaqueductal gray (pag) and anandamide (aea) increased in the cortex suggesting distinct regulation of the endocannabinoid system during headache pain. |
2021-04-21 |
2023-08-13 |
rat |
| Manuella Machado Godoi, Hélio Zangrossi Junior, Joice Maria da Cunha, Janaina Menezes Zanovel. Mu-opioid and CB1 cannabinoid receptors of the dorsal periaqueductal gray interplay in the regulation of fear response, but not antinociception. Pharmacology, biochemistry, and behavior. vol 194. 2021-03-30. PMID:32376258. |
mu-opioid and cb1 cannabinoid receptors of the dorsal periaqueductal gray interplay in the regulation of fear response, but not antinociception. |
2021-03-30 |
2023-08-13 |
Not clear |
| Udita Datta, Leslie K Kelley, Jason W Middleton, Nicholas W Gilpi. Positive allosteric modulation of the cannabinoid type-1 receptor (CB1R) in periaqueductal gray (PAG) antagonizes anti-nociceptive and cellular effects of a mu-opioid receptor agonist in morphine-withdrawn rats. Psychopharmacology. vol 237. issue 12. 2021-02-03. PMID:32857187. |
positive allosteric modulation of the cannabinoid type-1 receptor (cb1r) in periaqueductal gray (pag) antagonizes anti-nociceptive and cellular effects of a mu-opioid receptor agonist in morphine-withdrawn rats. |
2021-02-03 |
2023-08-13 |
rat |
| Esmaeal Tamaddonfard, Amir Erfanparast, Reza Salighedar, Sina Tamaddonfar. Medial prefrontal cortex diclofenac-induced antinociception is mediated through GPR55, cannabinoid CB1, and mu-opioid receptors of this area and periaqueductal gray. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 3. 2021-01-25. PMID:31641818. |
medial prefrontal cortex diclofenac-induced antinociception is mediated through gpr55, cannabinoid cb1, and mu-opioid receptors of this area and periaqueductal gray. |
2021-01-25 |
2023-08-13 |
Not clear |
| Esmaeal Tamaddonfard, Amir Erfanparast, Reza Salighedar, Sina Tamaddonfar. Medial prefrontal cortex diclofenac-induced antinociception is mediated through GPR55, cannabinoid CB1, and mu-opioid receptors of this area and periaqueductal gray. Naunyn-Schmiedeberg's archives of pharmacology. vol 393. issue 3. 2021-01-25. PMID:31641818. |
in the present study, the possible antinociceptive mechanisms induced by intra-medial prefrontal cortex (intra-mpfc) microinjection of diclofenac were investigated after blockade of gpr55, cannabinoid cb1, and mu-opioid receptors in this area and ventrolateral periaqueductal gray (vlpag). |
2021-01-25 |
2023-08-13 |
Not clear |
| Diego C Mascarenhas, Karina S Gomes, Tatiani Sorregotti, Ricardo L Nunes-de-Souz. Blockade of Cannabinoid CB1 Receptors in the Dorsal Periaqueductal Gray Unmasks the Antinociceptive Effect of Local Injections of Anandamide in Mice. Frontiers in pharmacology. vol 8. 2020-10-01. PMID:29046638. |
blockade of cannabinoid cb1 receptors in the dorsal periaqueductal gray unmasks the antinociceptive effect of local injections of anandamide in mice. |
2020-10-01 |
2023-08-13 |
mouse |
| Maryam Raoof, Mohammad Sofiabadi, Hashem Haghdoost-Yazdi, Razieh Kooshki, Mehdi Abbasneja. Blockage of ventrolateral periaqueductal gray matter cannabinoid 1 receptor increases dental pulp pain and pain-related subsequent learning and memory deficits in rats. Behavioural pharmacology. 2020-09-01. PMID:32483053. |
blockage of ventrolateral periaqueductal gray matter cannabinoid 1 receptor increases dental pulp pain and pain-related subsequent learning and memory deficits in rats. |
2020-09-01 |
2023-08-13 |
rat |
| Ruhan Deniz Topuz, Ozgur Gunduz, Cetin Hakan Karadag, Dikmen Dokmeci, Ahmet Ulugo. Endocannabinoid and N-acylethanolamide levels in rat brain and spinal cord following systemic dipyrone and paracetamol administration. Canadian journal of physiology and pharmacology. vol 97. issue 11. 2020-03-03. PMID:31283890. |
after administration of the highest doses of dipyrone and paracetamol, endocannabinoid (n-arachidonoylethanolamide (aea), 2-arachidonoylglycerol (2-ag)) and n-acylethanolamide (palmitoylethanolamide (pea), oleoylethanolamide (oea)) levels were measured in the periaqueductal gray (pag), rostral ventromedial medulla (rvm), and spinal cords of rats using tandem mass spectrometry with liquid chromatography. |
2020-03-03 |
2023-08-13 |
rat |
| Yi-Hung Chen, Hsin-Jung Lee, Ming Tatt Lee, Ya-Ting Wu, Yen-Hsien Lee, Ling-Ling Hwang, Ming-Shiu Hung, Andreas Zimmer, Ken Mackie, Lih-Chu Chio. Median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray. Proceedings of the National Academy of Sciences of the United States of America. vol 115. issue 45. 2019-05-22. PMID:30348772. |
median nerve stimulation induces analgesia via orexin-initiated endocannabinoid disinhibition in the periaqueductal gray. |
2019-05-22 |
2023-08-13 |
mouse |
| Franklin P Back, Antonio P Carobre. Periaqueductal gray glutamatergic, cannabinoid and vanilloid receptor interplay in defensive behavior and aversive memory formation. Neuropharmacology. vol 135. 2019-02-20. PMID:29596901. |
periaqueductal gray glutamatergic, cannabinoid and vanilloid receptor interplay in defensive behavior and aversive memory formation. |
2019-02-20 |
2023-08-13 |
rat |