| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Allison Campolo, Reed Pifer, Paul Shannon, Monica Crar. Microbial Adherence to Contact Lenses and Pathogens (Basel, Switzerland). vol 11. issue 11. 2022-11-24. PMID:36422634. |
microbial adherence to contact lenses and microbial keratitis (mk), the infection of the cornea, is a devastating disease and the fifth leading cause of blindness and visual impairment around the world. |
2022-11-24 |
2023-08-14 |
Not clear |
| Devanshu Gupta, Sachin Daigavan. A Clinical Case of Viral Keratitis. Cureus. vol 14. issue 10. 2022-11-21. PMID:36407263. |
the clinical features of this infection may range from pain and redness of the eye to scarring of the cornea or blindness. |
2022-11-21 |
2023-08-14 |
Not clear |
| Jacinta D Cleary, Orsolya Kekesi, Shaheen Hasmat, Tsu-Hui Hubert Low, Nigel H Lovell, Jonathan R Clark, Gregg J Suanin. Overcoming Facial Paralysis with an Implantable Actuator for Restoration of Blink. Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Annual International Conference. vol 2022. 2022-09-10. PMID:36085991. |
the delicate homeostasis of the eye is disrupted, and without frequent intervention, the cornea can become damaged, ultimately resulting in blindness. |
2022-09-10 |
2023-08-14 |
Not clear |
| Mohamadreza Aghamirsalim, Mohammadmahdi Mobaraki, Madjid Soltani, Mohammad Kiani Shahvandi, Mahmoud Jabbarvand, Elham Afzali, Kaamran Raahemifa. 3D Printed Hydrogels for Ocular Wound Healing. Biomedicines. vol 10. issue 7. 2022-07-27. PMID:35884865. |
presently, corneal transplantation is the only way to treat cornea blindness. |
2022-07-27 |
2023-08-14 |
Not clear |
| Steven Karamatic, Rebecca Goode, Niruba Bageswaran, Cali E Willet, Georgina Samaha, Ray Ferguson, Hamutal Mazrier, Claire M Wad. Genome-Wide Association Analysis for Chronic Superficial Keratitis in the Australian Racing Greyhound. Genes. vol 13. issue 8. 2022-07-27. PMID:35893065. |
chronic superficial keratitis (csk) is a progressive inflammatory condition of the eye (cornea) that can cause discomfort and blindness. |
2022-07-27 |
2023-08-14 |
dog |
| Claes Dohlma. The Boston Keratoprosthesis-The First 50 Years: Some Reminiscences. Annual review of vision science. 2022-07-14. PMID:35834821. |
additionally, the availability of donor cornea material can be limited, especially in underdeveloped countries where corneal blindness may also be highly prevalent. |
2022-07-14 |
2023-08-14 |
Not clear |
| Mohammad Mirazul Islam, Alexandru Chivu, Dina B AbuSamra, Amrita Saha, Sumit Chowdhuri, Bapan Pramanik, Claes H Dohlman, Debapratim Das, Pablo Argüeso, Jaya Rajaiya, Hirak K Patra, James Chodos. Crosslinker-free collagen gelation for corneal regeneration. Scientific reports. vol 12. issue 1. 2022-06-01. PMID:35650270. |
development of an artificial cornea can potentially fulfil the demand of donor corneas for transplantation as the number of donors is far less than needed to treat corneal blindness. |
2022-06-01 |
2023-08-13 |
human |
| Kai Wang, Li Jiang, Yueyang Zhong, Yin Zhang, Qichuan Yin, Su Li, Xiaobo Zhang, Haijie Han, Ke Ya. Ferrostatin-1-loaded liposome for treatment of corneal alkali burn via targeting ferroptosis. Bioengineering & translational medicine. vol 7. issue 2. 2022-05-23. PMID:35600640. |
during the progression of alkali burn-induced injury, overwhelmed oxidative stress in the cornea triggers cell damage, including oxidative changes in cellular macromolecules and lipid peroxidation in membranes, leading to impaired corneal transparency, decreased vision, or even blindness. |
2022-05-23 |
2023-08-13 |
Not clear |
| Zekai Cui, Kai Liao, Shenyang Li, Jianing Gu, Yini Wang, Chengcheng Ding, Yonglong Guo, Hon Fai Chan, Jacey Hongjie Ma, Shibo Tang, Jiansu Che. LM22B-10 promotes corneal nerve regeneration through in vitro 3D co-culture model and in vivo corneal injury model. Acta biomaterialia. 2022-05-13. PMID:35562005. |
corneal nerve wounding often causes abnormalities in the cornea and even blindness in severe cases. |
2022-05-13 |
2023-08-13 |
mouse |
| Diana Marie Battaglia, Maria D Sanchez-Pino, Charles D Nichols, Timothy P Foste. Herpes Simplex Virus-1 Induced Serotonin-Associated Metabolic Pathways Correlate With Severity of Virus- and Inflammation-Associated Ocular Disease. Frontiers in microbiology. vol 13. 2022-04-08. PMID:35391733. |
within the normally avascular and immunoprivileged cornea, hsv ocular infection can result in vision-threatening immune-mediated herpetic keratitis, the leading infectious cause of corneal blindness in the industrialized world. |
2022-04-08 |
2023-08-13 |
Not clear |
| Charles Costa de Farias, Fernanda Machado Bezerra, Luiz Luciano Lamazales, Walton Nosé, José Álvaro Pereira Gome. KeraKlear Artificial Cornea Implantation Assisted by Femtosecond Laser in Eyes With Aniridia. Cornea. vol 41. issue 5. 2022-04-06. PMID:35383618. |
the purpose of this study was to evaluate the feasibility of treating aniridia-associated keratopathy with a nonpenetrating artificial cornea in 2 patients with corneal blindness secondary to aniridia. |
2022-04-06 |
2023-08-13 |
Not clear |
| Wei Liang, Yingnan Zhang, Liang Zhou, Xiaoqin Lu, Margaret E Finn, Wei Wang, Hui Shao, Douglas C Dean, Lijun Zhang, Yongqing Li. Zeb1 regulation of wound-healing-induced inflammation in alkali-damaged corneas. iScience. vol 25. issue 4. 2022-03-28. PMID:35340433. |
alkali burn could cause severe traumatic damage on the cornea with inflammation and neovascularization (nv), leading to vision reduction and blindness. |
2022-03-28 |
2023-08-13 |
Not clear |
| Yee Ling Wong, Siyin Liu, Andrew Walkde. Current Perspectives on Corneal Transplantation (Part 2). Clinical ophthalmology (Auckland, N.Z.). vol 16. 2022-03-14. PMID:35282168. |
disease of the cornea is the third leading cause of blindness worldwide. |
2022-03-14 |
2023-08-13 |
Not clear |
| Siyin Liu, Yee Ling Wong, Andrew Walkde. Current Perspectives on Corneal Transplantation. Clinical ophthalmology (Auckland, N.Z.). vol 16. 2022-03-14. PMID:35282172. |
disease of the cornea is the third leading cause of blindness worldwide. |
2022-03-14 |
2023-08-13 |
Not clear |
| Shengbo Sang, Yayun Yan, Zhizhong Shen, Yanyan Cao, Qianqian Duan, Min He, Qiang Zhan. Photo-crosslinked hydrogels for tissue engineering of corneal epithelium. Experimental eye research. 2022-03-11. PMID:35276182. |
the vast majority of patients with corneal blindness cannot recover their vision due to the serious shortage of donor cornea. |
2022-03-11 |
2023-08-13 |
human |
| Carlos Daniel Diaz-Palomera, Isaac Alejandro Vidal-Paredes, Jose Navarro-Partida, Margarita Cid-Hernandez, Luis Carlos Rosales-Rivera, Ricardo De la Rosa-Bibiano, Hugo Christian Monroy-Ramirez, Arturo Santos, Juan Armendariz-Borund. Topical Pirfenidone-Loaded Liposomes Ophthalmic Formulation Reduces Haze Development after Corneal Alkali Burn in Mice. Pharmaceutics. vol 14. issue 2. 2022-02-26. PMID:35214048. |
corneal chemical burns (ccbs) frequently result in corneal fibrosis or haze, an opacity of the cornea that obstructs vision and induces corneal blindness. |
2022-02-26 |
2023-08-13 |
mouse |
| Esrin Aydin, Poshmaal Dhar, Moneisha Gokhale, Luke Chong, Serap Azizoglu, Cenk Suphiogl. A Review of Emerging Tear Proteomics Research on the Ocular Surface in Ocular Allergy. Biology. vol 11. issue 2. 2022-02-25. PMID:35205178. |
in keratoconus, the cornea begins to thin and sag over time, leading to progressive vision loss and blindness in severe conditions. |
2022-02-25 |
2023-08-13 |
Not clear |
| Julian Wolf, Rozina Ida Hajdu, Stefaniya Boneva, Anja Schlecht, Thabo Lapp, Katrin Wacker, Hansjürgen Agostini, Thomas Reinhard, Claudia Auw-Hädrich, Günther Schlunck, Clemens Lang. Characterization of the Cellular Microenvironment and Novel Specific Biomarkers in Pterygia Using RNA Sequencing. Frontiers in medicine. vol 8. 2022-02-17. PMID:35174178. |
with a worldwide prevalence of ~12%, pterygium is a common degenerative and environmentally triggered ocular surface disorder characterized by wing-shaped growth of conjunctival tissue onto the cornea that can lead to blindness if left untreated. |
2022-02-17 |
2023-08-13 |
Not clear |
| Prince K Akowuah, Angie De La Cruz, C Wayne Smith, Rolando E Rumbaut, Alan R Burn. An Epithelial Abrasion Model for Studying Corneal Wound Healing. Journal of visualized experiments : JoVE. issue 178. 2022-01-17. PMID:35037655. |
however, due to its external position, the cornea is highly susceptible to a wide variety of injuries that can lead to the loss of corneal transparency and eventual blindness. |
2022-01-17 |
2023-08-13 |
mouse |
| Jia-Horung Hung, Chaw-Ning Lee, Huai-Wen Hsu, I-Son Ng, Chi-Jung Wu, Chun-Keung Yu, Nan-Yao Lee, Yun Chang, Tak-Wah Won. Recent Advances in Photodynamic Therapy against Fungal Keratitis. Pharmaceutics. vol 13. issue 12. 2021-12-28. PMID:34959293. |
fungal keratitis is a serious clinical infection on the cornea caused by fungi and is one of the leading causes of blindness in asian countries. |
2021-12-28 |
2023-08-13 |
Not clear |