| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tzu-Yu Hou, Yun-Chen Chen, Chih-Chien Hs. Rapid resolution of stromal keratitis with the assistance of oral voriconazole in resistant acanthamoeba keratitis. Taiwan journal of ophthalmology. vol 7. issue 4. 2020-10-01. PMID:29296556. |
acanthamoeba keratitis (ak) is an unusual infectious disease of the cornea which sometimes leads to blindness. |
2020-10-01 |
2023-08-13 |
Not clear |
| I Haghani, F Amirinia, K Nowroozpoor-Dailami, T Shokoh. Detection of fungi by conventional methods and semi-nested PCR in patients with presumed fungal keratitis. Current medical mycology. vol 1. issue 2. 2020-09-30. PMID:28680986. |
fungal keratitis is a suppurative, ulcerative, and sight-threatening infection of the cornea that sometimes leads to blindness. |
2020-09-30 |
2023-08-13 |
Not clear |
| E S Saka, K F Monsudi, V Olatuj. TRAUMATIC CORNEAL LACERATION IN NORTHWESTERN NIGERIA. Journal of the West African College of Surgeons. vol 7. issue 4. 2020-09-30. PMID:30479992. |
cornea laceration generally leads to the development of corneal opacity which is a significant cause of blindness worldwide, particularly in developing countries where facility for corneal transplant is not readily available. |
2020-09-30 |
2023-08-13 |
human |
| Kai-Bao Ji, Ling Ling, Qian Zhang, Jing-Jing Chou, Xia-Ling Yang, Zhi-Hong Wang, Li Yin, Shu-Fang Wu, Yi-Feng Y. MicroRNA-296 mediated corneal neovascularization in an animal model of corneal burns after alkali exposures. Experimental and therapeutic medicine. vol 15. issue 1. 2020-09-29. PMID:29399058. |
alkali burns of the cornea may lead to permanent visual impairment or complete blindness. |
2020-09-29 |
2023-08-13 |
mouse |
| Mehrdad Mohammadpour, Zahra Heidari, Hassan Hashem. Updates on Managements for Keratoconus. Journal of current ophthalmology. vol 30. issue 2. 2020-09-28. PMID:29988906. |
keratoconus is a progressive disease of the cornea which can lead to blindness as irregular astigmatism increases. |
2020-09-28 |
2023-08-13 |
Not clear |
| Takuya Miyagawa, Zhi-Yu Chen, Che-Yi Chang, Ko-Hua Chen, Yang-Kao Wang, Guei-Sheung Liu, Ching-Li Tsen. Topical Application of Hyaluronic Acid-RGD Peptide-Coated Gelatin/Epigallocatechin-3 Gallate (EGCG) Nanoparticles Inhibits Corneal Neovascularization Via Inhibition of VEGF Production. Pharmaceutics. vol 12. issue 5. 2020-09-28. PMID:32354067. |
neovascularization (nv) of the cornea disrupts vision which leads to blindness. |
2020-09-28 |
2023-08-13 |
mouse |
| Yuxi Chen, Shengyao Zhi, Puping Liang, Qi Zheng, Mengni Liu, Qi Zhao, Jian Ren, Jun Cui, Junjiu Huang, Yizhi Liu, Zhou Songyan. Single AAV-Mediated CRISPR-SaCas9 Inhibits HSV-1 Replication by Editing ICP4 in Trigeminal Ganglion Neurons. Molecular therapy. Methods & clinical development. vol 18. 2020-09-28. PMID:32577430. |
herpes simplex keratitis (hsk) is the most common cause of corneal blindness in developed nations, caused by primary or recurrent herpes simplex virus 1 (hsv-1) infection of the cornea. |
2020-09-28 |
2023-08-13 |
Not clear |
| Pablo Argües. Galectins as Regulators of Corneal Inflammation. Current opinion in physiology. vol 19. 2020-09-28. PMID:32954114. |
infectious and inflammatory conditions can compromise the structure of the cornea, leading to visual impairment and blindness. |
2020-09-28 |
2023-08-13 |
Not clear |
| Cemile Kilic Bektas, Vasif Hasirc. Cell Loaded GelMA:HEMA IPN hydrogels for corneal stroma engineering. Journal of materials science. Materials in medicine. vol 31. issue 1. 2020-06-09. PMID:31811387. |
stroma is the main refractive element of the cornea and damage to it is one of the main causes of blindness. |
2020-06-09 |
2023-08-13 |
Not clear |
| Ilida Ortega, Robert McKean, Anthony J Ryan, Sheila MacNeil, Frederik Claeyssen. Characterisation and evaluation of the impact of microfabricated pockets on the performance of limbal epithelial stem cells in biodegradable PLGA membranes for corneal regeneration. Biomaterials science. vol 2. issue 5. 2020-06-02. PMID:32481846. |
scarring of the cornea affects thousands of people every year, significantly reducing the quality of life and potentially leading to corneal blindness. |
2020-06-02 |
2023-08-13 |
Not clear |
| A da S Diniz, L M Santo. [Vitamin A deficiency and xerophtalmia] Jornal de pediatria. vol 76 Suppl 3. 2020-04-14. PMID:14676909. |
results: clinical manifestations of xerophthalmia affect the retina (night blindness), the conjunctiva (conjunctival xerosis, with or without bitot spots), and the cornea (corneal xerosis). |
2020-04-14 |
2023-08-12 |
Not clear |
| Rashmi Singh, Noopur Gupta, M Vanathi, Radhika Tando. Corneal transplantation in the modern era. The Indian journal of medical research. vol 150. issue 1. 2020-04-06. PMID:31571625. |
corneal blindness is one of the major causes of reversible blindness, which can be managed with transplantation of a healthy donor cornea. |
2020-04-06 |
2023-08-13 |
human |
| A Enomoto, M Fukuda, K Matsunaga, S Kusaka, Y Shimomura, S Hamad. Contribution to oral and maxillary surgery and surgical technique of osteo-odontokeratoprosthesis in Japan. The British journal of oral & maxillofacial surgery. vol 57. issue 9. 2020-03-30. PMID:31378404. |
patients developed ocular blindness as a result of stevens-johnson syndrome, ocular cicatricial pemphigoid, and chemical and thermal burns to the cornea and ocular surface. |
2020-03-30 |
2023-08-13 |
Not clear |
| Akihisa Yamamoto, Hiroshi Tanaka, Munetoyo Toda, Chie Sotozono, Junji Hamuro, Shigeru Kinoshita, Morio Ueno, Motomu Tanak. A physical biomarker of the quality of cultured corneal endothelial cells and of the long-term prognosis of corneal restoration in patients. Nature biomedical engineering. vol 3. issue 12. 2020-03-09. PMID:31332343. |
dysfunction of the corneal endothelium reduces the transparency of the cornea and can cause blindness. |
2020-03-09 |
2023-08-13 |
Not clear |
| A H M Enayet Hussain, Junnatul Ferdoush, Saidur Rahman Mashreky, A K M Fazlur Rahman, Nahid Ferdausi, Koustuv Dala. Epidemiology of childhood blindness: A community-based study in Bangladesh. PloS one. vol 14. issue 6. 2020-02-03. PMID:31173584. |
the whole globe was the site responsible for binocular blindness (28.0%, 95% confidence interval [ci]: 13.1, 47.7), whereas the cornea was responsible for uniocular blindness (57.8%, 95% ci: 35.3, 78.1). |
2020-02-03 |
2023-08-13 |
Not clear |
| Qin Zhu, Yingting Zhu, Sean Tighe, Yongsong Liu, Min H. Engineering of Human Corneal Endothelial Cells International journal of medical sciences. vol 16. issue 4. 2019-12-02. PMID:31171901. |
currently, the only way to cure blindness caused by corneal endothelial dysfunction is via corneal transplantation of a cadaver donor cornea with healthy corneal endothelium. |
2019-12-02 |
2023-08-13 |
human |
| M Harissi-Dagher, E Sli. [Boston keratoprosthesis type 1]. Journal francais d'ophtalmologie. vol 42. issue 3. 2019-09-16. PMID:30857801. |
for more than two hundred years, researchers have been trying to find the best design of the artificial cornea in order to address these cases of severe corneal blindness. |
2019-09-16 |
2023-08-13 |
Not clear |
| Matthew L Hirsch, Laura M Conatser, Sara M Smith, Jacklyn H Salmon, Jerry Wu, Nicholas E Buglak, Rich Davis, Brian C Gilge. AAV vector-meditated expression of HLA-G reduces injury-induced corneal vascularization, immune cell infiltration, and fibrosis. Scientific reports. vol 7. issue 1. 2019-07-15. PMID:29259248. |
over 1.5 million individuals suffer from cornea vascularization due to genetic and/or environmental factors, compromising visual acuity and often resulting in blindness. |
2019-07-15 |
2023-08-13 |
human |
| M M Juárez, L I Tártara, A G Cid, J P Real, J M Bermúdez, V B Rajal, S D Palm. Acanthamoeba in the eye, can the parasite hide even more? Latest developments on the disease. Contact lens & anterior eye : the journal of the British Contact Lens Association. vol 41. issue 3. 2019-05-21. PMID:29273391. |
acanthamoeba keratitis (ak), a severe and painful eye infection, must be treated as soon as possible to prevent ulceration of the cornea, loss of visual acuity, and eventually blindness or enucleation. |
2019-05-21 |
2023-08-13 |
Not clear |
| Rachel E Riccio, Seo J Park, Richard Longnecker, Sarah J Kop. Characterization of Sex Differences in Ocular Herpes Simplex Virus 1 Infection and Herpes Stromal Keratitis Pathogenesis of Wild-Type and Herpesvirus Entry Mediator Knockout Mice. mSphere. vol 4. issue 2. 2019-05-20. PMID:30918059. |
herpes simplex virus 1 (hsv-1) causes chronic inflammatory disease in the cornea, an immune-privileged tissue, resulting in irreversible damage and blindness in affected individuals (a. rowe, a. st leger, s. jeon, d. k. dhaliwal, et al., prog retin eye res 32:88-101, 2013, https://doi.org/10.1016/j.preteyeres.2012.08.002). |
2019-05-20 |
2023-08-13 |
mouse |